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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 985 products of "Proteases/Proteasome"

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  • (1R,4S)-Yimitasvir diphosphate

    CAS:
    Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).
    Formula:C49H64N8O14P2
    Color and Shape:Solid
    Molecular weight:1051.03

    Ref: TM-T78669

    5mg
    To inquire
    50mg
    To inquire
  • MeOSuc-AAPV-CMK

    CAS:
    MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated
    Formula:C22H35ClN4O7
    Color and Shape:Solid
    Molecular weight:502.99

    Ref: TM-T78633

    5mg
    To inquire
    50mg
    To inquire
  • Ecallantide

    CAS:
    Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.
    Formula:C305H448N88O91S8
    Color and Shape:Solid
    Molecular weight:7059.88

    Ref: TM-T78572

    5mg
    To inquire
    50mg
    To inquire
  • LU-002i

    CAS:
    LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].
    Formula:C35H52N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:640.81

    Ref: TM-T81909

    5mg
    To inquire
    50mg
    To inquire
  • Z-DEVD-CMK

    CAS:
    Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].
    Formula:C27H35ClN4O12
    Color and Shape:Solid
    Molecular weight:643.04

    Ref: TM-T80660

    5mg
    To inquire
    50mg
    To inquire
  • ABP 25

    CAS:
    ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.
    Formula:C55H66ClN5O3
    Color and Shape:Solid
    Molecular weight:880.6

    Ref: TM-T74154

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • DCLK1-IN-2

    CAS:
    DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell
    Formula:C26H32N8O3S
    Color and Shape:Solid
    Molecular weight:536.65

    Ref: TM-T79421

    5mg
    To inquire
    50mg
    To inquire
  • MK-0674

    CAS:
    MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.
    Formula:C26H27F6N3O2
    Purity:97.3% - 99.91%
    Color and Shape:Solid
    Molecular weight:527.5

    Ref: TM-T16089

    1mg
    264.00€
    5mg
    610.00€
    10mg
    827.00€
    25mg
    1,224.00€
  • ZED-1227

    CAS:

    ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas

    Formula:C26H36N6O6
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:528.6

    Ref: TM-T17289

    1mg
    248.00€
    5mg
    553.00€
    10mg
    847.00€
    25mg
    1,549.00€
    50mg
    2,670.00€
  • BMS-212122

    CAS:
    BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.
    Formula:C43H36F6N4O2
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:754.76

    Ref: TM-T30506

    1mg
    315.00€
    5mg
    745.00€
    10mg
    1,018.00€
    25mg
    1,431.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
    500mg
    4,410.00€
  • HIV-1 inhibitor-54

    CAS:
    HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.
    Formula:C27H30N6O4S
    Purity:98.05% - 99.39%
    Color and Shape:Soild
    Molecular weight:534.63

    Ref: TM-T67833

    1mg
    89.00€
    5mg
    172.00€
    10mg
    254.00€
    25mg
    393.00€
    50mg
    562.00€
    100mg
    778.00€
    200mg
    1,035.00€
  • γ-Glu-Tyr

    CAS:
    gamma-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide against dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.
    Formula:C14H18N2O6
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:310.3

    Ref: TM-T78223

    2mg
    To inquire
    5mg
    50.00€
    10mg
    79.00€
    25mg
    133.00€
    50mg
    197.00€
    100mg
    290.00€
  • Aderamastat

    CAS:
    Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.
    Formula:C21H18N2O4S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:394.44

    Ref: TM-T83168

    1mg
    94.00€
    5mg
    222.00€
    10mg
    356.00€
    25mg
    713.00€
    50mg
    1,153.00€
    100mg
    1,783.00€
  • Collagen proline hydroxylase inhibitor-1

    CAS:
    Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。
    Formula:C24H21N5O4
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:443.45

    Ref: TM-T10861

    1mg
    86.00€
    5mg
    180.00€
    10mg
    245.00€
    25mg
    374.00€
    50mg
    504.00€
    100mg
    662.00€
    200mg
    875.00€
  • Nesbuvir

    CAS:
    Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.
    Formula:C22H23FN2O5S
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:446.49

    Ref: TM-TQ0090

    1mg
    60.00€
    2mg
    88.00€
    5mg
    133.00€
    10mg
    173.00€
    25mg
    301.00€
    50mg
    442.00€
    100mg
    577.00€
    200mg
    780.00€
    1mL*10mM (DMSO)
    147.00€
  • VBY-825

    CAS:
    VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
    Formula:C23H29F4N3O5S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:535.55

    Ref: TM-T13288

    1mg
    250.00€
    2mg
    371.00€
    5mg
    620.00€
    10mg
    882.00€
    25mg
    1,314.00€
    50mg
    1,765.00€
    100mg
    2,385.00€
  • Cathepsin C-IN-5

    CAS:
    Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.
    Formula:C21H17ClN6OS
    Color and Shape:Solid
    Molecular weight:436.92

    Ref: TM-T62494

    25mg
    768.00€
    50mg
    999.00€
    100mg
    1,449.00€
  • DPP-4-IN-15

    CAS:
    DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.
    Formula:C17H14F3N3O2S
    Color and Shape:Solid
    Molecular weight:381.372

    Ref: TM-T205036

    10mg
    To inquire
    50mg
    To inquire
  • HCV-IN-7

    CAS:
    HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H48N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:768.92

    Ref: TM-T11548

    25mg
    2,313.00€
    50mg
    3,042.00€
    100mg
    4,140.00€
  • Idraparinux Na

    CAS:
    Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor
    Formula:C38H55Na9O49S7
    Color and Shape:Solid
    Molecular weight:1727.14

    Ref: TM-T70536

    25mg
    6,094.00€
    50mg
    8,082.00€
    100mg
    11,700.00€