
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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MMP-7-IN-2
CAS:<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Formula:C28H40ClF3N6O9SPurity:97.82%Color and Shape:SolidMolecular weight:729.17Proteasome β2c/i-IN-1
CAS:<p>Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].</p>Formula:C32H48N4O7Purity:98%Color and Shape:SolidMolecular weight:600.75ND-378
CAS:<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Formula:C18H19NO4S2Purity:98%Color and Shape:SolidMolecular weight:377.48AZD-7295
CAS:<p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>Formula:C32H35F3N4O5SColor and Shape:SolidMolecular weight:644.7PTC725
CAS:<p>PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.</p>Formula:C23H18F4N6O2SPurity:98%Color and Shape:SolidMolecular weight:518.49EP1013
CAS:<p>EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.</p>Formula:C18H23FN2O6Purity:98%Color and Shape:SolidMolecular weight:382.38HIV-1 protease-IN-12
CAS:<p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63GSK-2485852
CAS:<p>GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.</p>Formula:C27H25BF2N2O6SColor and Shape:SolidMolecular weight:554.37MMP13-IN-3
CAS:<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Formula:C24H22N4O5Purity:99.76%Color and Shape:SolidMolecular weight:446.46TP0556351
CAS:<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Formula:C50H70N10O16Purity:98%Color and Shape:SolidMolecular weight:1067.15Apratastat
CAS:<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Formula:C17H22N2O6S2Purity:98%Color and Shape:SolidMolecular weight:414.5MDL-101146, (R)-
CAS:<p>MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.</p>Formula:C29H37F5N4O6Purity:98%Color and Shape:SolidMolecular weight:632.62LU-002i
CAS:<p>LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].</p>Formula:C35H52N4O7Purity:98%Color and Shape:SolidMolecular weight:640.81Phe-Pro-Ala-pNA
CAS:<p>Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.</p>Formula:C23H27N5O5Color and Shape:SolidMolecular weight:453.49Flovagatran sodium
CAS:<p>Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.</p>Formula:C27H36BN3NaO7Purity:98%Color and Shape:SolidMolecular weight:548.4Z-FG-NHO-BzOME
CAS:<p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>Formula:C27H27N3O7Color and Shape:SolidMolecular weight:505.52HIV-1 protease-IN-7
CAS:<p>HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].</p>Formula:C68H104N10O12SPurity:98%Color and Shape:SolidMolecular weight:1285.68BAY-320
CAS:<p>BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.</p>Formula:C26H26F2N6O2Purity:98%Color and Shape:SolidMolecular weight:492.52Cyclotheonellazole A
CAS:<p>Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.</p>Formula:C44H54N9NaO14S2Color and Shape:SolidMolecular weight:1020.07JTK-853
CAS:<p>JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).</p>Formula:C28H23F7N6O4S2Purity:98%Color and Shape:SolidMolecular weight:704.64

