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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • MMP-7-IN-2

    CAS:
    <p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>
    Formula:C28H40ClF3N6O9S
    Purity:97.82%
    Color and Shape:Solid
    Molecular weight:729.17
  • Proteasome β2c/i-IN-1

    CAS:
    <p>Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].</p>
    Formula:C32H48N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:600.75
  • ND-378

    CAS:
    <p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>
    Formula:C18H19NO4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.48
  • AZD-7295

    CAS:
    <p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>
    Formula:C32H35F3N4O5S
    Color and Shape:Solid
    Molecular weight:644.7
  • PTC725

    CAS:
    <p>PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.</p>
    Formula:C23H18F4N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:518.49
  • EP1013

    CAS:
    <p>EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.</p>
    Formula:C18H23FN2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:382.38
  • HIV-1 protease-IN-12

    CAS:
    <p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>
    Formula:C25H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:489.63
  • GSK-2485852

    CAS:
    <p>GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.</p>
    Formula:C27H25BF2N2O6S
    Color and Shape:Solid
    Molecular weight:554.37
  • MMP13-IN-3

    CAS:
    <p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, &gt;1000x selective, for osteoarthritis treatment.</p>
    Formula:C24H22N4O5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:446.46
  • TP0556351

    CAS:
    <p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>
    Formula:C50H70N10O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1067.15
  • Apratastat

    CAS:
    <p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>
    Formula:C17H22N2O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.5
  • MDL-101146, (R)-

    CAS:
    <p>MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.</p>
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62
  • LU-002i

    CAS:
    <p>LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].</p>
    Formula:C35H52N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:640.81
  • Phe-Pro-Ala-pNA

    CAS:
    <p>Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.</p>
    Formula:C23H27N5O5
    Color and Shape:Solid
    Molecular weight:453.49
  • Flovagatran sodium

    CAS:
    <p>Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.</p>
    Formula:C27H36BN3NaO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:548.4
  • Z-FG-NHO-BzOME

    CAS:
    <p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>
    Formula:C27H27N3O7
    Color and Shape:Solid
    Molecular weight:505.52
  • HIV-1 protease-IN-7

    CAS:
    <p>HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].</p>
    Formula:C68H104N10O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1285.68
  • BAY-320

    CAS:
    <p>BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.</p>
    Formula:C26H26F2N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.52
  • Cyclotheonellazole A

    CAS:
    <p>Cyclotheonellazole A inhibits elastase (IC50=0.034nM) &amp; chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.</p>
    Formula:C44H54N9NaO14S2
    Color and Shape:Solid
    Molecular weight:1020.07
  • JTK-853

    CAS:
    <p>JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).</p>
    Formula:C28H23F7N6O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:704.64