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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 984 products of "Proteases/Proteasome"

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  • GSK5852


    GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.
    Formula:C27H27BF2N2O6S
    Color and Shape:Solid
    Molecular weight:556.39

    Ref: TM-T63936

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Tyrosinase-IN-29

    CAS:
    Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.
    Formula:C10H9NO2
    Color and Shape:Solid
    Molecular weight:175.18

    Ref: TM-T88534

    10mg
    To inquire
    50mg
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  • SAR107375

    CAS:
    SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].
    Formula:C24H30ClN5O5S2
    Color and Shape:Solid
    Molecular weight:568.11

    Ref: TM-T87355

    10mg
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    50mg
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  • TG-2-IN-4

    CAS:
    TG-2-IN-4 (compound 8), an inhibitor of transglutaminase 2 (TG2) with an IC 50 value of less than 0.5 mM, is utilized in the study of inflammatory disorders [1].
    Formula:C34H40N6O5
    Color and Shape:Solid
    Molecular weight:612.72

    Ref: TM-T87508

    10mg
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    50mg
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  • JBIR-22

    CAS:
    JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.
    Formula:C23H33NO6
    Color and Shape:Solid
    Molecular weight:419.51

    Ref: TM-T71203

    25mg
    2,448.00€
    50mg
    3,222.00€
    100mg
    4,410.00€
  • BAY-7598

    CAS:
    BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).
    Formula:C28H31N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.56

    Ref: TM-T10474

    25mg
    3,348.00€
    50mg
    4,213.00€
    100mg
    5,580.00€
  • Narlaprevir

    CAS:
    Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.
    Formula:C36H61N5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:707.96

    Ref: TM-T16274

    2mg
    225.00€
  • GW311616 hydrochloride

    CAS:
    GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
    Formula:C19H32ClN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.99

    Ref: TM-T11525L

    1mg
    273.00€
    5mg
    818.00€
    10mg
    1,359.00€
  • AEP-IN-1


    APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.
    Formula:C18H27N3O3
    Color and Shape:Solid
    Molecular weight:333.43

    Ref: TM-T61004

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • SMCypI C31


    SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).
    Formula:C27H30N4O2S
    Color and Shape:Solid
    Molecular weight:474.62

    Ref: TM-T63090

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AMG-222 tosylate

    CAS:
    AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.
    Formula:C39H47N9O6S
    Color and Shape:Solid
    Molecular weight:769.91

    Ref: TM-T71354

    25mg
    3,664.00€
    50mg
    4,843.00€
    100mg
    6,840.00€
  • Cathepsin C-IN-4


    Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).
    Formula:C21H14ClF3N4S
    Color and Shape:Solid
    Molecular weight:446.88

    Ref: TM-T62659

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Freselestat

    CAS:
    Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.
    Formula:C23H28N6O4
    Color and Shape:Solid
    Molecular weight:452.51

    Ref: TM-T31877

    10mg
    396.00€
  • MeO-Suc-Ala-Ala-Pro-Ala-CMK

    CAS:
    MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).
    Formula:C20H31ClN4O7
    Color and Shape:Solid
    Molecular weight:474.936

    Ref: TM-T206832

    10mg
    To inquire
    50mg
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  • Napsagatran hydrate

    CAS:
    Napsagatran hydrate is a novel and specific inhibitor of thrombin.
    Formula:C26H36N6O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:576.66

    Ref: TM-T16273

    25mg
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    50mg
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    100mg
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  • Ciluprevir

    CAS:
    Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.
    Formula:C40H50N6O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:774.93

    Ref: TM-T19627

    25mg
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    50mg
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    100mg
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  • Isobutylamido thiazolyl resorcinol

    CAS:
    Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.
    Formula:C13H14N2O3S
    Color and Shape:Solid
    Molecular weight:278.33

    Ref: TM-T201683

    10mg
    To inquire
    50mg
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  • Piceid 6″-O-azelaic acid ester


    Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.
    Formula:C24H36O10
    Color and Shape:Solid
    Molecular weight:484.54

    Ref: TM-T63219

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • GSK-2878175

    CAS:
    GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.
    Formula:C27H23BClFN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:568.81

    Ref: TM-T27470

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • 3-Aminobenzene-1,2-diol

    CAS:
    3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.
    Formula:C6H7NO2
    Color and Shape:Solid
    Molecular weight:125.13

    Ref: TM-T201595

    10mg
    To inquire
    50mg
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