
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
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Found 1045 products of "Proteases/Proteasome"
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(2R,3S)-Emricasan
CAS:<p>(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.</p>Formula:C26H27F4N3O7Color and Shape:SolidMolecular weight:569.5Beclabuvir
CAS:<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Formula:C36H45N5O5SPurity:99.87% - 99.93%Color and Shape:SolidMolecular weight:659.84Immunoproteasome activator 1
CAS:<p>Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.</p>Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.46UK-370106
CAS:<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Formula:C35H44N2O5Purity:98%Color and Shape:SolidMolecular weight:572.73Isobutylamido thiazolyl resorcinol
CAS:<p>Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.</p>Formula:C13H14N2O3SColor and Shape:SolidMolecular weight:278.33LK-732
CAS:<p>LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.</p>Formula:C25H29N5O3SColor and Shape:SolidMolecular weight:479.59Boc3Arg
<p>Boc 3 Arg is a tert-butyl carbamate-protected arginine compound. It serves as an efficient tag that induces degradation by directly targeting proteins to the 20S proteasome.</p>Formula:C21H39N5O7Color and Shape:SolidMolecular weight:473.563-Aminobenzene-1,2-diol
CAS:<p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>Formula:C6H7NO2Color and Shape:SolidMolecular weight:125.13TGase2-IN-1
CAS:<p>TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.</p>Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46Tyrosinase-IN-39
<p>Tyrosinase-IN-39 (compound 5r) is a competitive inhibitor of tyrosinase, with an IC50 of 6.4 μM, and is used in the study of skin diseases.</p>Formula:C23H19N5O4S2Color and Shape:SolidMolecular weight:493.56SCO-792
<p>SCO-792: potent, reversible oral enteropeptidase inhibitor, with slow in vitro dissociation and in vivo protein digestion blocking.</p>Formula:C22H22N4O8·xH2OColor and Shape:SolidPNU-248686A
CAS:<p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>Formula:C22H18ClNaO5S2Purity:98%Color and Shape:SolidMolecular weight:484.95CM-352
CAS:<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Formula:C24H29N3O6SPurity:99.36%Color and Shape:SolidMolecular weight:487.57DPP-4-IN-15
CAS:<p>DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.</p>Formula:C17H14F3N3O2SColor and Shape:SolidMolecular weight:381.372UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formula:C34H43N3O4Purity:98%Color and Shape:SolidMolecular weight:557.72Verducatib
CAS:<p>Verducatib is an inhibitor of cathepsins (cathepsin).</p>Formula:C31H35FN4O3Color and Shape:SolidMolecular weight:530.633Anti-infective agent 10
CAS:<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formula:C26H25N3O7SColor and Shape:SolidMolecular weight:523.56HCV-IN-40
CAS:<p>HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.</p>Formula:C21H26BrFN3O9PColor and Shape:SolidMolecular weight:594.32RBx-0597
CAS:<p>RBx-0597 is a selective DPP-IV inhibitor with IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. It is utilized in research focused on type 2 diabetes.</p>Formula:C19H20F2N4O2Color and Shape:SolidMolecular weight:374.384GB111-NH2
CAS:<p>GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].</p>Formula:C33H39N3O6Color and Shape:SolidMolecular weight:573.68

