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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • GSK-A1

    CAS:
    <p>GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression.</p>
    Formula:C29H27FN6O4S
    Purity:98.03% - 98.97%
    Color and Shape:Solid
    Molecular weight:574.63
  • Carbobenzoxyproline

    CAS:
    <p>Carbobenzoxyproline (Carbobenzoxy-S-proline) is a prolidase inhibitor.</p>
    Formula:C13H15NO4
    Purity:99.79%
    Color and Shape:White To Light Yellow Crystal Powder
    Molecular weight:249.26
  • PF-00835231

    CAS:
    <p>PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-</p>
    Formula:C24H32N4O6
    Purity:97.83%
    Color and Shape:Solid
    Molecular weight:472.53
  • CH 5450

    CAS:
    <p>CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) (Z-Ile-Glu-Pro-Phe-Ome) is a short peptide inhibitor of chymase in the human heart</p>
    Formula:C34H44N4O9
    Purity:95.93%
    Color and Shape:Solid
    Molecular weight:652.73
  • Rusalatide acetate (497221-38-2 free base)

    CAS:
    <p>Rusalatide acetate (TP508 amide acetate), a regenerated peptide, alleviates radiation-induced gastrointestinal injury by activating stem cells.</p>
    Formula:C99H151N29O37S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:2371.5
  • Hepln-13

    CAS:
    <p>Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.</p>
    Formula:C17H13BrN2
    Purity:97.67%
    Color and Shape:Solid
    Molecular weight:325.2
  • (Arg)9 TFA (143413-47-2 free base)

    CAS:
    <p>(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.</p>
    Formula:C56H111F3N36O12
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:1537.71
  • 4-Isopropylcatechol

    CAS:
    <p>4-Isopropylcatechol is a potent depigmenting agent and is of use in the topical therapy of selected patients with hypermelanosis.</p>
    Formula:C9H12O2
    Purity:97.93%
    Color and Shape:Solid
    Molecular weight:152.19
  • Azvudine

    CAS:
    <p>Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.</p>
    Formula:C9H11FN6O4
    Purity:99.76% - >99.99%
    Color and Shape:Solid
    Molecular weight:286.22
  • Z-YVAD-FMK

    CAS:
    <p>AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.</p>
    Formula:C31H39FN4O9
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:630.66
  • Enfuvirtide acetate

    CAS:
    <p>Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.</p>
    Formula:C206H305N51O66
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:4552
  • Diprotin A

    CAS:
    <p>Diprotin A (Ile-Pro-Ile) (Ile-Pro-Ile) is a dipeptidyl peptidase IV (DPP-IV) inhibitor.</p>
    Formula:C17H31N3O4
    Purity:99.29%
    Color and Shape:White Powder
    Molecular weight:341.45
  • GI254023X

    CAS:
    <p>GI254023X is a MMP9 and ADAM10 inhibitor with IC50 values ​​of 2.5 and 5.3 nM.Cost-effective and quality-assured.</p>
    Formula:C21H33N3O4
    Purity:98.21% - 98.56%
    Color and Shape:Solid
    Molecular weight:391.5
  • Paritaprevir free base

    CAS:
    <p>Paritaprevir (ABT-450) is an oral HCV NS3/NS4A protease inhibitor with potential against genotype 1, disrupting viral replication.</p>
    Formula:C40H43N7O7S
    Purity:95% - 99.26%
    Color and Shape:Solid
    Molecular weight:765.89
  • Bictegravir

    CAS:
    <p>Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).</p>
    Formula:C21H18F3N3O5
    Purity:97.6% - 99.51%
    Color and Shape:Solid
    Molecular weight:449.38
  • ABT530

    CAS:
    <p>ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.</p>
    Formula:C57H65F5N10O8
    Purity:99.15% - 99.93%
    Color and Shape:Solid
    Molecular weight:1113.18
  • TMC647055 Choline Hydroxide Salt


    <p>TMC647055 is a potent HCV NS5B inhibitor with low toxicity and good pharmacokinetics, under clinical evaluation.</p>
    Formula:C37H53N5O8S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:727.91
  • Brensocatib

    CAS:
    <p>Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).</p>
    Formula:C23H24N4O4
    Purity:97.55%
    Color and Shape:Solid
    Molecular weight:420.46
  • Apelin-17 (human, bovine) acetate


    <p>Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).</p>
    Formula:C98H160N34O22S
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:2198.63
  • Rilpivirine

    CAS:
    <p>Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment</p>
    Formula:C22H18N6
    Purity:97.22% - 98.83%
    Color and Shape:Solid
    Molecular weight:366.42
  • CASP3 Activator 1541

    CAS:
    <p>CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.</p>
    Formula:C24H17N3O4
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:411.41
  • EIDD-1931

    CAS:
    <p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>
    Formula:C9H13N3O6
    Purity:99.14% - 99.73%
    Color and Shape:Solid
    Molecular weight:259.22
  • GSK-690693

    CAS:
    <p>GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.</p>
    Formula:C21H27N7O3
    Purity:98.07% - 99.77%
    Color and Shape:Solid
    Molecular weight:425.48
  • 3-O-Ethyl-L-ascorbic acid

    CAS:
    <p>3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative.</p>
    Formula:C8H12O6
    Purity:97.35% - 99.99%
    Color and Shape:White To Very Pale Yellow Crystalline Powder Solid Powder
    Molecular weight:204.18
  • PSI-6130

    CAS:
    <p>PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.</p>
    Formula:C10H14FN3O4
    Purity:98.63% - 99.79%
    Color and Shape:Solid
    Molecular weight:259.23
  • Asunaprevir

    CAS:
    <p>Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.</p>
    Formula:C35H46ClN5O9S
    Purity:99.34% - 99.8%
    Color and Shape:Solid
    Molecular weight:748.29
  • PTACH

    CAS:
    <p>PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).</p>
    Formula:C20H26N2O2S2
    Purity:87.44% - 99.74%
    Color and Shape:Solid
    Molecular weight:390.56
  • Daclatasvir

    CAS:
    <p>Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.</p>
    Formula:C40H50N8O6
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:738.88
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Formula:C19H31N3O6
    Purity:97.26% - 99.58%
    Color and Shape:Solid
    Molecular weight:397.47
  • Peptide T acetate(106362-32-7 free base)


    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Formula:C37H59N9O18
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:917.91
  • Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Formula:C29H28F4N4O4
    Purity:99.85% - 99.87%
    Color and Shape:Solid
    Molecular weight:572.55
  • Bemnifosbuvir

    CAS:
    <p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>
    Formula:C24H33FN7O7P
    Purity:99.35% - 99.54%
    Color and Shape:Solid
    Molecular weight:581.53
  • LY 3000328

    CAS:
    <p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>
    Formula:C25H29FN4O5
    Purity:97.83% - 99.54%
    Color and Shape:Solid
    Molecular weight:484.52
  • 4-Butylresorcinol

    CAS:
    <p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>
    Formula:C10H14O2
    Purity:98.64% - ≥95%
    Color and Shape:Light Beige Solid Powder
    Molecular weight:166.22
  • Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Formula:C40H52Cl2N8O6
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:811.8
  • Ixazomib citrate

    CAS:
    <p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>
    Formula:C20H23BCl2N2O9
    Purity:98.37% - >99.99%
    Color and Shape:Solid
    Molecular weight:517.12
  • Paritaprevir

    CAS:
    <p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>
    Formula:C40H43N7O7S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:765.88
  • Avatrombopag

    CAS:
    <p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>
    Formula:C29H34Cl2N6O3S2
    Purity:99.01% - 99.63%
    Color and Shape:Solid
    Molecular weight:649.65
  • S 3304

    CAS:
    <p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>
    Formula:C24H20N2O4S2
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:464.56
  • Velpatasvir

    CAS:
    <p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>
    Formula:C49H54N8O8
    Purity:99.17% - 99.83%
    Color and Shape:Solid
    Molecular weight:883
  • Boc-Asp(OMe)-fluoromethyl ketone

    CAS:
    <p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>
    Formula:C11H18FNO5
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:263.26
  • Obefazimod

    CAS:
    <p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>
    Formula:C16H10ClF3N2O
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:338.71
  • KKI-5 acetate(97145-43-2 free base)


    <p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>
    Formula:C37H59N11O11
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:833.95
  • Tris(4-aminophenyl)methane

    CAS:
    <p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>
    Formula:C19H19N3
    Purity:95.73%
    Color and Shape:Beige Solid Crystalline
    Molecular weight:289.37
  • JNJ0966

    CAS:
    <p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>
    Formula:C16H16N4O2S2
    Purity:99.46% - 99.62%
    Color and Shape:Solid
    Molecular weight:360.45
  • Omarigliptin

    CAS:
    <p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>
    Formula:C17H20F2N4O3S
    Purity:99.68% - 99.77%
    Color and Shape:Solid
    Molecular weight:398.43
  • Thiamine disulfide

    CAS:
    <p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>
    Formula:C24H34N8O4S2
    Purity:99.81%
    Color and Shape:Coa
    Molecular weight:562.71
  • Y-29794 Tosylate

    CAS:
    <p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>
    Formula:C30H42N2O4S3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:590.86
  • GK921

    CAS:
    <p>GK921 is a transglutaminase 2 (TGase) inhibitor.</p>
    Formula:C21H20N4O
    Purity:97.44% - 99.49%
    Color and Shape:Solid
    Molecular weight:344.41
  • HIV-1 Inhibitor 18A

    CAS:
    <p>HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.</p>
    Formula:C14H11N5O2S
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:313.33