
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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GSK-A1
CAS:<p>GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression.</p>Formula:C29H27FN6O4SPurity:98.03% - 98.97%Color and Shape:SolidMolecular weight:574.63Carbobenzoxyproline
CAS:<p>Carbobenzoxyproline (Carbobenzoxy-S-proline) is a prolidase inhibitor.</p>Formula:C13H15NO4Purity:99.79%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:249.26PF-00835231
CAS:<p>PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-</p>Formula:C24H32N4O6Purity:97.83%Color and Shape:SolidMolecular weight:472.53CH 5450
CAS:<p>CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) (Z-Ile-Glu-Pro-Phe-Ome) is a short peptide inhibitor of chymase in the human heart</p>Formula:C34H44N4O9Purity:95.93%Color and Shape:SolidMolecular weight:652.73Rusalatide acetate (497221-38-2 free base)
CAS:<p>Rusalatide acetate (TP508 amide acetate), a regenerated peptide, alleviates radiation-induced gastrointestinal injury by activating stem cells.</p>Formula:C99H151N29O37SPurity:>99.99%Color and Shape:SolidMolecular weight:2371.5Hepln-13
CAS:<p>Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.</p>Formula:C17H13BrN2Purity:97.67%Color and Shape:SolidMolecular weight:325.2(Arg)9 TFA (143413-47-2 free base)
CAS:<p>(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.</p>Formula:C56H111F3N36O12Purity:>99.99%Color and Shape:SolidMolecular weight:1537.714-Isopropylcatechol
CAS:<p>4-Isopropylcatechol is a potent depigmenting agent and is of use in the topical therapy of selected patients with hypermelanosis.</p>Formula:C9H12O2Purity:97.93%Color and Shape:SolidMolecular weight:152.19Azvudine
CAS:<p>Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.</p>Formula:C9H11FN6O4Purity:99.76% - >99.99%Color and Shape:SolidMolecular weight:286.22Z-YVAD-FMK
CAS:<p>AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.</p>Formula:C31H39FN4O9Purity:98.00%Color and Shape:SolidMolecular weight:630.66Enfuvirtide acetate
CAS:<p>Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.</p>Formula:C206H305N51O66Purity:99.34%Color and Shape:SolidMolecular weight:4552Diprotin A
CAS:<p>Diprotin A (Ile-Pro-Ile) (Ile-Pro-Ile) is a dipeptidyl peptidase IV (DPP-IV) inhibitor.</p>Formula:C17H31N3O4Purity:99.29%Color and Shape:White PowderMolecular weight:341.45GI254023X
CAS:<p>GI254023X is a MMP9 and ADAM10 inhibitor with IC50 values of 2.5 and 5.3 nM.Cost-effective and quality-assured.</p>Formula:C21H33N3O4Purity:98.21% - 98.56%Color and Shape:SolidMolecular weight:391.5Paritaprevir free base
CAS:<p>Paritaprevir (ABT-450) is an oral HCV NS3/NS4A protease inhibitor with potential against genotype 1, disrupting viral replication.</p>Formula:C40H43N7O7SPurity:95% - 99.26%Color and Shape:SolidMolecular weight:765.89Bictegravir
CAS:<p>Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).</p>Formula:C21H18F3N3O5Purity:97.6% - 99.51%Color and Shape:SolidMolecular weight:449.38ABT530
CAS:<p>ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.</p>Formula:C57H65F5N10O8Purity:99.15% - 99.93%Color and Shape:SolidMolecular weight:1113.18TMC647055 Choline Hydroxide Salt
<p>TMC647055 is a potent HCV NS5B inhibitor with low toxicity and good pharmacokinetics, under clinical evaluation.</p>Formula:C37H53N5O8SPurity:99.44%Color and Shape:SolidMolecular weight:727.91Brensocatib
CAS:<p>Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).</p>Formula:C23H24N4O4Purity:97.55%Color and Shape:SolidMolecular weight:420.46Apelin-17 (human, bovine) acetate
<p>Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).</p>Formula:C98H160N34O22SPurity:99.36%Color and Shape:SolidMolecular weight:2198.63Rilpivirine
CAS:<p>Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment</p>Formula:C22H18N6Purity:97.22% - 98.83%Color and Shape:SolidMolecular weight:366.42CASP3 Activator 1541
CAS:<p>CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.</p>Formula:C24H17N3O4Purity:98.84%Color and Shape:SolidMolecular weight:411.41EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C9H13N3O6Purity:99.14% - 99.73%Color and Shape:SolidMolecular weight:259.22GSK-690693
CAS:<p>GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.</p>Formula:C21H27N7O3Purity:98.07% - 99.77%Color and Shape:SolidMolecular weight:425.483-O-Ethyl-L-ascorbic acid
CAS:<p>3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative.</p>Formula:C8H12O6Purity:97.35% - 99.99%Color and Shape:White To Very Pale Yellow Crystalline Powder Solid PowderMolecular weight:204.18PSI-6130
CAS:<p>PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.</p>Formula:C10H14FN3O4Purity:98.63% - 99.79%Color and Shape:SolidMolecular weight:259.23Asunaprevir
CAS:<p>Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.</p>Formula:C35H46ClN5O9SPurity:99.34% - 99.8%Color and Shape:SolidMolecular weight:748.29PTACH
CAS:<p>PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).</p>Formula:C20H26N2O2S2Purity:87.44% - 99.74%Color and Shape:SolidMolecular weight:390.56Daclatasvir
CAS:<p>Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.</p>Formula:C40H50N8O6Purity:99.81%Color and Shape:SolidMolecular weight:738.88CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Formula:C19H31N3O6Purity:97.26% - 99.58%Color and Shape:SolidMolecular weight:397.47Peptide T acetate(106362-32-7 free base)
<p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>Formula:C37H59N9O18Purity:99.47%Color and Shape:SolidMolecular weight:917.91Letermovir
CAS:<p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>Formula:C29H28F4N4O4Purity:99.85% - 99.87%Color and Shape:SolidMolecular weight:572.55Bemnifosbuvir
CAS:<p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>Formula:C24H33FN7O7PPurity:99.35% - 99.54%Color and Shape:SolidMolecular weight:581.53LY 3000328
CAS:<p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>Formula:C25H29FN4O5Purity:97.83% - 99.54%Color and Shape:SolidMolecular weight:484.524-Butylresorcinol
CAS:<p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>Formula:C10H14O2Purity:98.64% - ≥95%Color and Shape:Light Beige Solid PowderMolecular weight:166.22Daclatasvir dihydrochloride
CAS:<p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>Formula:C40H52Cl2N8O6Purity:99.67%Color and Shape:SolidMolecular weight:811.8Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.12Paritaprevir
CAS:<p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>Formula:C40H43N7O7SPurity:99.72%Color and Shape:SolidMolecular weight:765.88Avatrombopag
CAS:<p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>Formula:C29H34Cl2N6O3S2Purity:99.01% - 99.63%Color and Shape:SolidMolecular weight:649.65S 3304
CAS:<p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>Formula:C24H20N2O4S2Purity:98.09%Color and Shape:SolidMolecular weight:464.56Velpatasvir
CAS:<p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>Formula:C49H54N8O8Purity:99.17% - 99.83%Color and Shape:SolidMolecular weight:883Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Formula:C16H10ClF3N2OPurity:99.86%Color and Shape:SolidMolecular weight:338.71KKI-5 acetate(97145-43-2 free base)
<p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>Formula:C37H59N11O11Purity:99.44%Color and Shape:SolidMolecular weight:833.95Tris(4-aminophenyl)methane
CAS:<p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>Formula:C19H19N3Purity:95.73%Color and Shape:Beige Solid CrystallineMolecular weight:289.37JNJ0966
CAS:<p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>Formula:C16H16N4O2S2Purity:99.46% - 99.62%Color and Shape:SolidMolecular weight:360.45Omarigliptin
CAS:<p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>Formula:C17H20F2N4O3SPurity:99.68% - 99.77%Color and Shape:SolidMolecular weight:398.43Thiamine disulfide
CAS:<p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>Formula:C24H34N8O4S2Purity:99.81%Color and Shape:CoaMolecular weight:562.71Y-29794 Tosylate
CAS:<p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>Formula:C30H42N2O4S3Purity:99.86%Color and Shape:SolidMolecular weight:590.86GK921
CAS:<p>GK921 is a transglutaminase 2 (TGase) inhibitor.</p>Formula:C21H20N4OPurity:97.44% - 99.49%Color and Shape:SolidMolecular weight:344.41HIV-1 Inhibitor 18A
CAS:<p>HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.</p>Formula:C14H11N5O2SPurity:99.79%Color and Shape:SolidMolecular weight:313.33
