
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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BR351
CAS:<p>BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Formula:C20H25FN2O5SPurity:98%Color and Shape:SolidMolecular weight:424.49BMS-986094
CAS:<p>INX 08189 is an RNA-directed RNA polymerase (NS5B) inhibitor.</p>Formula:C30H39N6O9PColor and Shape:SolidMolecular weight:658.64(S)-BI-1001
CAS:<p>(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).</p>Formula:C19H15BrClNO3Purity:98%Color and Shape:SolidMolecular weight:420.68JPM-OEt
CAS:<p>JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.</p>Formula:C20H28N2O6Purity:98%Color and Shape:SolidMolecular weight:392.45LB-30057
CAS:<p>LB-30057 is used as an oral thrombin inhibitor.</p>Formula:C26H31N5O3SPurity:98%Color and Shape:SolidMolecular weight:493.62Grazoprevir sodium salt
CAS:<p>Grazoprevir sodium salt is a selective Hepatitis C virus NS3/4a protease inhibitor with broad activity across genotypes and resistant variants.</p>Formula:C38H50N6NaO9SPurity:98%Color and Shape:SolidMolecular weight:789.9Anticancer agent 82
CAS:<p>Anticancer agent 82, a FiVe1 derivative, selectively targets VIM in cancer cells to disrupt mitosis, with improved oral bioavailability.</p>Formula:C19H18Cl2N4OColor and Shape:SolidMolecular weight:389.28U 27391
CAS:<p>U 27391 is a metalloproteinase inhibitor. It acts by inhibits the action of human recombinant interleukin-1beta and glycosaminoglycan synthesis.</p>Formula:C23H36N4O5Purity:98%Color and Shape:SolidMolecular weight:448.56Tyrosinase-IN-4
CAS:<p>Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.</p>Formula:C15H9ClO3Color and Shape:SolidMolecular weight:272.68Gemigliptin Tartrate(911637-19-9 free base)
CAS:<p>Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4).</p>Formula:C22H25F8N5O8Purity:>99.99%Color and Shape:SolidMolecular weight:639.45Cysteine protease inhibitor-2
CAS:<p>Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.</p>Formula:C13H5N5OPurity:98%Color and Shape:SolidMolecular weight:247.21ZD8321
CAS:<p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>Formula:C18H28F3N3O5Purity:98%Color and Shape:SolidMolecular weight:423.43Proteasome-IN-1
CAS:<p>Proteasome-IN-1 is an inhibitor of proteasome.</p>Formula:C42H35N5O3Purity:98%Color and Shape:SolidMolecular weight:657.76Tanomastat
CAS:<p>Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.</p>Formula:C23H19ClO3SPurity:98%Color and Shape:SolidMolecular weight:410.91MDL-101146, (S)-
CAS:<p>MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.</p>Formula:C29H37F5N4O6Purity:98%Color and Shape:SolidMolecular weight:632.62IMB-26
CAS:<p>IMB-26 is an HCV inhibitor (EC50: 2.1 μM) and has shown potent anti-HCV effects.</p>Formula:C20H23BrN2O6Color and Shape:SolidMolecular weight:467.31Tyrosinase-IN-6
CAS:<p>Tyrosinase-IN-6 (4B) is a potent tyrosinase inhibitor (IC50=3.80 μM) with good antioxidant activity.</p>Formula:C24H31N3O2Color and Shape:SolidMolecular weight:393.52ZD-0892
CAS:<p>ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).</p>Formula:C24H32F3N3O5Purity:95% - 99.53%Color and Shape:SolidMolecular weight:499.52SLK/STK10-IN-1
CAS:<p>SLK/STK10-IN-1 is a selective and potent inhibitor of SLK and STK10 with potential antitumor activity.</p>Formula:C17H13ClN2O3Purity:99.34%Color and Shape:SolidMolecular weight:328.75Prodipine hydrochloride
CAS:<p>Prodipine hydrochloride for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit (IC50 of 4.5 μM and 30 μM, respectively).</p>Formula:C20H26ClNPurity:98%Color and Shape:SolidMolecular weight:315.88DTS
CAS:<p>DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.</p>Formula:C14H14S3Purity:98%Color and Shape:SolidMolecular weight:278.46TAPI-1
CAS:<p>TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.</p>Formula:C26H37N5O5Purity:≥95%Color and Shape:SolidMolecular weight:499.6ZYZ-488
CAS:<p>ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.</p>Formula:C20H29N3O11Purity:99.04%Color and Shape:SolidMolecular weight:487.46Desethyl KBT-3022
CAS:<p>Desethyl KBT-3022 is an active metabolite of the antiplatelet compound KBT-3022.</p>Formula:C23H20N2O4SPurity:98%Color and Shape:SolidMolecular weight:420.48ND-322 HCl
CAS:<p>ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.</p>Formula:C15H16ClNO3S2Purity:99.49%Color and Shape:SolidMolecular weight:357.88Cyclophilin inhibitor 3
CAS:<p>Cyclophilin inhibitor 3 (compound 7c), a potent inhibitor of cyclophilin A (CypA), exhibited potent anti-HCV effects with an EC50 value of 4.2 μM.</p>Formula:C34H38N4O6Color and Shape:SolidMolecular weight:598.69STOCK2S-26016
CAS:<p>WNK-IN-B, a cell-permeable diaminoacridine, selectively inhibits WNK signaling in mpkDCT/MOVAS by targeting SPAK/OSR1 CCT domain.</p>Formula:C20H19N3O2Color and Shape:SolidMolecular weight:333.38MMP13-IN-4
CAS:<p>MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].</p>Formula:C21H17BrN4O5Purity:98%Color and Shape:SolidMolecular weight:485.29Efegatran sulfate
CAS:<p>Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.</p>Formula:C21H34N6O7SPurity:≥98% - ≥98%Color and Shape:SolidMolecular weight:514.6Desirudin
CAS:<p>Desirudin (CGP 39393) inhibits thrombin, prevents thrombosis, and is used in thrombocytopenia research.</p>Color and Shape:SolidZ-LLF-CHO
CAS:<p>Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.</p>Formula:C29H39N3O5Purity:98%Color and Shape:SolidMolecular weight:509.64SJA6017
CAS:<p>SJA6017: inhibits calpain-1/2, cathepsins B/L; prevents apoptosis, protects spinal cord, boosts function. IC50s: 7.5-78 nM.</p>Formula:C17H25FN2O4SPurity:98%Color and Shape:SolidMolecular weight:372.45AA9 TG2 inhibitor
CAS:<p>AA9 is a novel transglutaminase (TG2) inhibitor.</p>Formula:C32H36N4O5Color and Shape:SolidMolecular weight:556.65GS-9256
CAS:<p>GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].</p>Formula:C46H56ClF2N6O8PSPurity:98%Color and Shape:SolidMolecular weight:957.46Cysteine Protease inhibitor
CAS:<p>Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine Protease</p>Formula:C18H14N4OPurity:98%Color and Shape:SolidMolecular weight:302.33SQ 32602
CAS:<p>SQ 32602 is a cathepsin E inhibitor.</p>Formula:C32H52N3O7PColor and Shape:SolidMolecular weight:621.74Tyrosinase-IN-8
<p>Tyrosinase-IN-8, a potent inhibitor of tyrosinase, demonstrates an inhibitory concentration (IC 50) value of 1.6 µM and exhibits low cytotoxicity while</p>Formula:C16H12O4Color and Shape:SolidMolecular weight:268.26Alicapistat
CAS:<p>Alicapistat (ABT-957) is a human calpains 1 and 2 inhibitor. It can potentially be used to treat Alzheimer's disease (AD).</p>Formula:C25H27N3O4Purity:98%Color and Shape:SolidMolecular weight:433.5VEL-0230
CAS:<p>VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.</p>Formula:C14H24NNaO5Color and Shape:SolidMolecular weight:309.33JNJ-10329670
CAS:<p>JNJ 10329670 is a highly potent (Ki of approximately 30 nM), nonpeptidic, noncovalent inhibitor of human cathepsin S with immunosuppressive activity.</p>Formula:C30H34ClF3N6O3SColor and Shape:SolidMolecular weight:651.14BMS-488043
CAS:<p>BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+)</p>Formula:C22H22N4O5Purity:99.95%Color and Shape:SolidMolecular weight:422.43BAY-43-9695
CAS:<p>BAY-43-9695 is a non-nucleoside compound with anti-human cytomegalovirus (HCMV) activity. It is the major metabolite of BAY-38-4766.</p>Formula:C22H25N3O4SPurity:99.50% - 99.65%Color and Shape:SolidMolecular weight:427.52BMS-929075
CAS:<p>BMS-929075 is an orally active HCV NS5B replicase (HCV NS5B replicase) palm site variant inhibitor with potency, high oral bioavailability and pharmacokinetic</p>Formula:C31H24F2N4O3Purity:98.44% - 99.94%Color and Shape:SolidMolecular weight:538.54NP-313
CAS:<p>NP-313 (NSC-4264) is a potent antithrombotic that blocks platelet aggregation via thromboxane A2 synthesis inhibition and targets SOCC-mediated Ca2+ efflux.</p>Formula:C12H8ClNO3Purity:98.97%Color and Shape:SolidMolecular weight:249.65TY-51469
CAS:<p>TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).</p>Formula:C20H15FN2O6S4Purity:99.65%Color and Shape:SolidMolecular weight:526.6CZL55
CAS:<p>CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).</p>Formula:C20H22N2O6Purity:98.19%Color and Shape:SolidMolecular weight:386.4(2RS)-FPMPA
CAS:<p>(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).</p>Formula:C9H13FN5O4PPurity:99.9% - >99.99%Color and Shape:SolidMolecular weight:305.2GSK-364735
CAS:<p>GSK-364735 is an HIV-1 IN inhibitor.</p>Formula:C19H18FN3O4Purity:97.73%Color and Shape:SolidMolecular weight:371.36TG2-IN-3h
CAS:<p>TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitor</p>Formula:C21H26N4O4SPurity:99.34% - 99.76%Color and Shape:SolidMolecular weight:430.52UPGL00004
CAS:<p>UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.</p>Formula:C25H26N8O2S2Purity:97.93%Color and Shape:SolidMolecular weight:534.66
