
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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KB-R7785
CAS:<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Formula:C18H27N3O4Color and Shape:SolidMolecular weight:349.42Cipemastat
CAS:<p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>Formula:C22H36N4O5Purity:98%Color and Shape:SolidMolecular weight:436.55Azt-pmap
CAS:<p>AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].</p>Formula:C20H25N6O8PPurity:98%Color and Shape:SolidMolecular weight:508.42XL-784 free base
CAS:<p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>Formula:C21H22ClF2N3O8SPurity:98%Color and Shape:SolidMolecular weight:549.93MDL 27324
CAS:<p>MDL 27324 is an inhibitor of human neutrophil elastase.</p>Formula:C29H38F3N5O6SPurity:98%Color and Shape:SolidMolecular weight:641.7AA74-1
CAS:<p>AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].</p>Formula:C16H28N4O2Purity:98%Color and Shape:SolidMolecular weight:308.42Ro 32-7315
CAS:<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Formula:C22H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:453.6MK-3281
CAS:<p>MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.</p>Formula:C29H37N3O3Color and Shape:SolidMolecular weight:475.62MDL 101146
CAS:<p>MDL 101146 is an orally active neutrophil elastase inhibitor.</p>Formula:C29H37F5N4O6Purity:98%Color and Shape:SolidMolecular weight:632.62JW 480
CAS:<p>JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.</p>Formula:C22H23NO2Purity:99.72%Color and Shape:SolidMolecular weight:333.42MMP-7-IN-2
CAS:<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Formula:C28H40ClF3N6O9SPurity:97.82%Color and Shape:SolidMolecular weight:729.17Proteasome β2c/i-IN-1
CAS:<p>Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].</p>Formula:C32H48N4O7Purity:98%Color and Shape:SolidMolecular weight:600.75ND-378
CAS:<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Formula:C18H19NO4S2Purity:98%Color and Shape:SolidMolecular weight:377.48AZD-7295
CAS:<p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>Formula:C32H35F3N4O5SColor and Shape:SolidMolecular weight:644.7PTC725
CAS:<p>PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.</p>Formula:C23H18F4N6O2SPurity:98%Color and Shape:SolidMolecular weight:518.49EP1013
CAS:<p>EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.</p>Formula:C18H23FN2O6Purity:98%Color and Shape:SolidMolecular weight:382.38HIV-1 protease-IN-12
CAS:<p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63GSK-2485852
CAS:<p>GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.</p>Formula:C27H25BF2N2O6SColor and Shape:SolidMolecular weight:554.37MMP13-IN-3
CAS:<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Formula:C24H22N4O5Purity:99.76%Color and Shape:SolidMolecular weight:446.46TP0556351
CAS:<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Formula:C50H70N10O16Purity:98%Color and Shape:SolidMolecular weight:1067.15Apratastat
CAS:<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Formula:C17H22N2O6S2Purity:98%Color and Shape:SolidMolecular weight:414.5MDL-101146, (R)-
CAS:<p>MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.</p>Formula:C29H37F5N4O6Purity:98%Color and Shape:SolidMolecular weight:632.62LU-002i
CAS:<p>LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].</p>Formula:C35H52N4O7Purity:98%Color and Shape:SolidMolecular weight:640.81Phe-Pro-Ala-pNA
CAS:<p>Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.</p>Formula:C23H27N5O5Color and Shape:SolidMolecular weight:453.49Flovagatran sodium
CAS:<p>Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.</p>Formula:C27H36BN3NaO7Purity:98%Color and Shape:SolidMolecular weight:548.4Z-FG-NHO-BzOME
CAS:<p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>Formula:C27H27N3O7Color and Shape:SolidMolecular weight:505.52HIV-1 protease-IN-7
CAS:<p>HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].</p>Formula:C68H104N10O12SPurity:98%Color and Shape:SolidMolecular weight:1285.68BAY-320
CAS:<p>BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.</p>Formula:C26H26F2N6O2Purity:98%Color and Shape:SolidMolecular weight:492.52Cyclotheonellazole A
CAS:<p>Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.</p>Formula:C44H54N9NaO14S2Color and Shape:SolidMolecular weight:1020.07JTK-853
CAS:<p>JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).</p>Formula:C28H23F7N6O4S2Purity:98%Color and Shape:SolidMolecular weight:704.64Z-PDLDA-NHOH
CAS:<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Formula:C22H32N4O6Color and Shape:SolidMolecular weight:448.51HIV-1 protease-IN-9
CAS:<p>HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a</p>Formula:C37H41N7O4SPurity:98%Color and Shape:SolidMolecular weight:679.83DCLK1-IN-2
CAS:<p>DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell</p>Formula:C26H32N8O3SColor and Shape:SolidMolecular weight:536.65Berotralstat HCl
CAS:<p>Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.</p>Formula:C30H28Cl2F4N6OColor and Shape:SolidMolecular weight:635.4886Z-DEVD-CMK
CAS:<p>Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].</p>Formula:C27H35ClN4O12Color and Shape:SolidMolecular weight:643.04I-XW-053
CAS:<p>I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-</p>Formula:C22H16N2O2Purity:99.05%Color and Shape:SolidMolecular weight:340.37O-Benzoylhydroxylamine
CAS:<p>O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].</p>Formula:C7H7NO2Color and Shape:SolidMolecular weight:137.14Kallikrein-IN-2
CAS:<p>Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>Formula:C28H25F3N4O4Color and Shape:SolidMolecular weight:538.52Neurodegenerative Disorder-Targeting Compound 1
CAS:<p>Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].</p>Formula:C28H28N4O4Purity:98%Color and Shape:SolidMolecular weight:484.55NCI-B16
CAS:<p>NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].</p>Formula:C27H26N8O4Color and Shape:SolidMolecular weight:526.55KCC009
CAS:<p>KCC009 is a potent and selective Transglutaminase 2 Inhibitor.</p>Formula:C21H22BrN3O5Color and Shape:SolidMolecular weight:476.32SQ 32056
CAS:<p>SQ 32056 is a cathepsin E inhibitor.</p>Formula:C37H56N4O5Purity:98%Color and Shape:SolidMolecular weight:636.86BMS-189664 HCl
CAS:<p>BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.</p>Formula:C22H35ClN6O4SPurity:98%Color and Shape:SolidMolecular weight:515.07Ecallantide
CAS:<p>Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.</p>Formula:C305H448N88O91S8Color and Shape:SolidMolecular weight:7059.88Proteasome-IN-4
<p>Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.</p>Formula:C44H58N6O5Color and Shape:SolidMolecular weight:750.97MMP-145
CAS:<p>MMP-145 is used as a protease inhibitor.</p>Formula:C20H20N2O7SPurity:98%Color and Shape:SolidMolecular weight:432.45HIV-1 protease-IN-8
CAS:<p>HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.</p>Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63Human enteropeptidase-IN-1
CAS:<p>Enteropeptidase-IN-1: orally active, potent inhibitor, low systemic exposure, for anti-obesity research.</p>Formula:C20H18N4O7Color and Shape:SolidMolecular weight:426.38MeOSuc-AAPV-CMK
CAS:<p>MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated</p>Formula:C22H35ClN4O7Color and Shape:SolidMolecular weight:502.99NK3201
CAS:<p>NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.</p>Formula:C31H29N5O6Purity:98%Color and Shape:SolidMolecular weight:567.59

