
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Sucunamostat
CAS:<p>Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.</p>Formula:C22H22N4O8Color and Shape:SolidMolecular weight:470.438Sulodexide
CAS:<p>Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.</p>Color and Shape:SolidTWH106
<p>TWH106 is an inhibitor of the cyclophilin (Cyp) enzyme, exhibiting strong affinity for CypA and CypB with dissociation constants (KD) of 53 nM and 139 nM, respectively. It effectively inhibits the replication of HIV and HCV, demonstrating antiviral activity.</p>Color and Shape:Odour SolidApovincamine
CAS:<p>Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, which is a derivative of Vincamine with vasodilating activity.</p>Formula:C21H24N2O2Purity:98%Color and Shape:SolidMolecular weight:336.44Ecallantide TFA
<p>Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of</p>Color and Shape:Odour SolidGSK2818713
CAS:<p>GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.</p>Formula:C46H56N8O8Color and Shape:SolidMolecular weight:849.002Chymotrypsinogen
CAS:<p>Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .</p>Color and Shape:SolidHistatin 5
CAS:<p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>Formula:C133H195N51O33Purity:98%Color and Shape:SolidMolecular weight:3036.29STK33-IN-1
CAS:<p>STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.</p>Formula:C24H27N7O2Color and Shape:SolidMolecular weight:445.527MK-6169
CAS:<p>MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.</p>Formula:C54H62FN9O8SPurity:98%Color and Shape:SolidMolecular weight:1016.2Suc-AAP-Abu-pNA
CAS:<p>Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,</p>Formula:C25H34N6O9Color and Shape:SolidMolecular weight:562.57PS 915
CAS:<p>PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.</p>Formula:C27H36ClN7O6Purity:98%Color and Shape:SolidMolecular weight:590.08Elastatinal
CAS:<p>Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.</p>Formula:C21H36N8O7Color and Shape:Yellowish SolidMolecular weight:512.56JC-10
CAS:<p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>Formula:C25H29Cl2IN4Purity:95%Color and Shape:SolidMolecular weight:583.34α 1 Antichymotrypsin, Human Plasma
CAS:<p>Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.</p>Color and Shape:SolidHIV-1 TAT (48-60) Acetate
<p>Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.</p>Formula:C72H135N35O18Purity:99.93%Color and Shape:SoildMolecular weight:1779.07Paritaprevir dihydrate
CAS:<p>Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.</p>Formula:C40H47N7O9SColor and Shape:SolidMolecular weight:801.91L-Methionine-DL-sulfoximine
CAS:<p>MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.</p>Formula:C5H12N2O3SPurity:99.56% - ≥98%Color and Shape:White Crystalline PowderMolecular weight:180.23Fotagliptin
CAS:<p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>Formula:C17H19FN6OColor and Shape:SolidMolecular weight:342.37Proteasome-IN-7
<p>Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.</p>Formula:C48H56N6O10SColor and Shape:SolidMolecular weight:909.06Sofosbuvir impurity A
CAS:<p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45MMP-3 Inhibitor
CAS:<p>MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.</p>Formula:C27H46N10O9SPurity:98.87%Color and Shape:SolidMolecular weight:686.78Carboxypeptidase C
CAS:<p>Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.</p>Color and Shape:SolidSofosbuvir impurity H
<p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>Formula:C29H33FN3O10PPurity:98%Color and Shape:SolidMolecular weight:633.56Lonodelestat TFA
<p>Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.</p>Formula:C73H112F3N15O21Color and Shape:SolidMolecular weight:1592.75TAPI1 acetate
<p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>Formula:C28H41N5O7Purity:98.82% - 99.94%Color and Shape:SolidMolecular weight:559.65Tiprelestat
CAS:<p>Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.</p>Formula:C254H416N72O75S10Color and Shape:SolidMolecular weight:5999.09TMC647055 Choline salt
<p>TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).</p>Formula:C37H53N5O8SPurity:98%Color and Shape:SolidMolecular weight:727.91Cathepsin C-IN-6
<p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>Formula:C24H35N5O4·xC2HF3O2Color and Shape:SolidFFAGLDD TFA
<p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>Formula:C39H50F3N7O14Purity:98%Color and Shape:SolidMolecular weight:897.85BMS 180742
CAS:<p>BMS 180742 is an exosite inhibitor of thrombin.</p>Formula:C67H93N11O22Purity:98%Color and Shape:SolidMolecular weight:1404.52Neutrophil elastase inhibitor 4
<p>Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.</p>Formula:C20H21N3O5Color and Shape:SolidMolecular weight:383.4Rivulariapeptolides 1155
<p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>Formula:C59H81N9O15Color and Shape:SolidMolecular weight:1156.33NS5A-IN-4
CAS:<p>NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.</p>Formula:C47H48N8O6Color and Shape:SolidMolecular weight:820.93Alisporivir
CAS:<p>Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.</p>Formula:C63H113N11O12Purity:99.95%Color and Shape:SolidMolecular weight:1216.64Nostopeptin B
CAS:<p>Nostopeptin B is an inhibitor of elastase.</p>Formula:C46H70N8O12Color and Shape:SolidMolecular weight:927.11Sofosbuvir impurity J
CAS:<p>Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Formula:C22H30FN4O8PPurity:98%Color and Shape:SolidMolecular weight:528.47Ac-PAL-AMC
CAS:<p>Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.</p>Formula:C26H34N4O6Color and Shape:SolidMolecular weight:498.57Fibrinopeptide B, human
CAS:<p>Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.</p>Formula:C66H93N19O25Purity:98%Color and Shape:SolidMolecular weight:1552.56GCPII-IN-1
CAS:<p>GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.</p>Formula:C12H21N3O7Color and Shape:SolidMolecular weight:319.314Calpain Inhibitor-1
CAS:<p>Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.</p>Formula:C19H17FN6O5SColor and Shape:SolidMolecular weight:460.44Dutogliptin tartrate
CAS:<p>Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.</p>Formula:C14H26BN3O9Purity:98%Color and Shape:SolidMolecular weight:391.18Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Formula:C27H32N4O6SColor and Shape:SolidMolecular weight:540.64PF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Formula:C25H20N2O3SPurity:99.35%Color and Shape:SolidMolecular weight:428.5CRA-2059 TFA
<p>CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Color and Shape:SolidEP 171
CAS:<p>EP 171 is a potent agonist of TP-receptors.</p>Formula:C23H29FO5Color and Shape:SolidMolecular weight:404.47Ichorcumab
CAS:<p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Color and Shape:LiquidHCV-IN-7 hydrochloride
CAS:<p>HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Formula:C40H50Cl2N8O6SPurity:98%Color and Shape:SolidMolecular weight:841.85HIV-1 inhibitor-6
CAS:<p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>Formula:C14H10N4O4SPurity:99.33%Color and Shape:SolidMolecular weight:330.32CRA-2059 hydrochloride
<p>CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Color and Shape:Solid

