
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(46 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(55 products)
- Proteasome(87 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 987 products of "Proteases/Proteasome"
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AR-H067637
CAS:AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.Formula:C21H21ClF2N4O4Color and Shape:SolidMolecular weight:466.87Enzyme-IN-1
CAS:Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。Formula:C36H50N4O7Color and Shape:SolidMolecular weight:650.8Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofColor and Shape:Odour SolidCerpegin
CAS:Cerpegin, a pyridine ketone fused c-lactone, acts as an inhibitor of the 20S proteasome. It possesses pharmacological properties as a neuropsychiatric sedative, anti-inflammatory, analgesic, and exhibits anti-ulcer activity.Formula:C10H11NO3Color and Shape:SolidMolecular weight:193.2Tiprelestat
CAS:Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.Formula:C254H416N72O75S10Color and Shape:SolidMolecular weight:5999.09ZG36
ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrialColor and Shape:Odour SolidAlisporivir
CAS:Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.Formula:C63H113N11O12Purity:99.95%Color and Shape:SolidMolecular weight:1216.64Rivulariapeptolides 988
Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).Formula:C50H68N8O13Color and Shape:SolidMolecular weight:989.12Carboxypeptidase C
CAS:Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.Color and Shape:SolidMicropeptin 478A
CAS:Micropeptin 478A is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.Formula:C40H62ClN9O15SPurity:98%Color and Shape:SolidMolecular weight:976.49Sofosbuvir impurity I
Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C21H27FN3O9PPurity:98%Color and Shape:SolidMolecular weight:515.43Sofosbuvir impurity K
CAS:Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H29ClN3O9PPurity:98%Color and Shape:SolidMolecular weight:545.91Cajaninstilbene acid
CAS:Cajaninstilbene acid is a useful organic compound for research related to life sciences. The catalog number is T124035 and the CAS number is 87402-84-4.Formula:C21H22O4Color and Shape:SolidMolecular weight:338.403MMP-12 Inhibitor
CAS:MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
Formula:C19H20N2O7SPurity:97.51% - 99.96%Color and Shape:SoildMolecular weight:420.44Isoleucylvaline
CAS:Isoleucylvaline is a dipeptide.Formula:C11H22N2O3Color and Shape:SolidMolecular weight:230.30GCPII-IN-1
CAS:GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.
Formula:C12H21N3O7Color and Shape:SolidMolecular weight:319.314N-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Formula:C33H36N6O6Purity:98%Color and Shape:White To Off-White PowderMolecular weight:612.68Fibrinopeptide B, human
CAS:Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formula:C66H93N19O25Purity:98%Color and Shape:SolidMolecular weight:1552.56Chetoseminudin B
CAS:Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].Formula:C17H21N3O3S2Color and Shape:SolidMolecular weight:379.5Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Formula:C25H34O8Color and Shape:SolidMolecular weight:462.53Ac-DEMEEC-OH
CAS:Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.Formula:C29H44N6O16S2Color and Shape:SolidMolecular weight:796.82NS5A-IN-1
NS5A-IN-1 is a proagent of the HCV NS5A inhibitor Pibrentasvir (ABT-530).Formula:C72H86F5N10O14PColor and Shape:SolidMolecular weight:1441.48Nostopeptin B
CAS:Nostopeptin B is an inhibitor of elastase.Formula:C46H70N8O12Color and Shape:SolidMolecular weight:927.11Sofigatran
CAS:Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.Formula:C24H44N4O4SColor and Shape:SolidMolecular weight:484.7MMP-9-IN-6
CAS:MMP-9-IN-6: MMP-9 inhibitor, IC50 of 50 µM, anti-ulcer, potential anti-tumor, for tissue repair studies.Formula:C25H19NO2Purity:98.96%Color and Shape:SoildMolecular weight:365.42AL-611
CAS:AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).
Formula:C25H33F2N6O8PColor and Shape:SolidMolecular weight:614.544L 659286
CAS:L 659286 is one kind of cephalosporin derivative.Formula:C17H21N5O7S2Color and Shape:SolidMolecular weight:471.51Talabostat isomer mesylate
Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).Formula:C10H23BN2O6SPurity:98%Color and Shape:SolidMolecular weight:310.18Ac-Phe-Gly-pNA
CAS:Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .Formula:C19H20N4O5Color and Shape:SolidMolecular weight:384.39Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
CAS:Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).Formula:C49H68N14O12SColor and Shape:SolidMolecular weight:1077.22Dutogliptin
CAS:Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Formula:C10H20BN3O3Purity:98%Color and Shape:SolidMolecular weight:241.10Ac-PLVE-FMK
CAS:Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].Formula:C25H41FN4O7Purity:98%Color and Shape:SolidMolecular weight:528.61Acetyl-Calpastatin(184-210)(human)
CAS:Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.Formula:C142H230N36O44SPurity:98%Color and Shape:SolidMolecular weight:3177.65TP0597850
CAS:TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].Formula:C41H57N9O13SColor and Shape:SolidMolecular weight:916.01AP-C2
CAS:AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.Formula:C18H16N4SPurity:99.99%Color and Shape:SoildMolecular weight:320.41(-)-Taxifolin
CAS:(-)-Taxifolin, less active enantiomer with anti-tyrosinase, collagenase inhibition (IC50 = 193.3 μM), antifibrotic, antioxidant properties.Formula:C15H12O7Color and Shape:SolidMolecular weight:304.25Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formula:C15H19NO3Color and Shape:SolidMolecular weight:261.32Linagliptin Methyldimer
CAS:Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.Formula:C50H56N16O4Purity:99.91%Color and Shape:SolidMolecular weight:945.08C-telopeptide
CAS:C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.Formula:C34H56N14O13Purity:98%Color and Shape:SolidMolecular weight:868.9Aristololactam IIIa
CAS:Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.Formula:C16H9NO4Color and Shape:SolidMolecular weight:279.25Histargin
CAS:Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.Formula:C14H25N7O4Color and Shape:SolidMolecular weight:355.39Rivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).Formula:C56H83N9O15Color and Shape:SolidMolecular weight:1122.31KKI-5
CAS:KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.
Formula:C35H55N11O9Purity:98%Color and Shape:SolidMolecular weight:773.88Zetomipzomib maleate
CAS:Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.Formula:C34H46N4O12Color and Shape:SolidMolecular weight:702.758HCVP-IN-1
CAS:HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.Formula:C30H34FN5O3Color and Shape:SolidMolecular weight:531.632Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormula:C47H64N14O10Color and Shape:SolidMolecular weight:985.1NVP-DPP728 dihydrochloride
CAS:NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.Formula:C15H20Cl2N6OColor and Shape:SolidMolecular weight:371.27Pirmitegravir
CAS:Pirmitegravir (STP0404) is a potent ALLINI, blocks LEDGF/p75 site, shows antiviral action against HIV.
Formula:C27H31ClN4O3Purity:99.79% - 99.79%Color and Shape:SolidMolecular weight:495.01PPACK II
CAS:PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .Formula:C25H33ClN6O3Color and Shape:SolidMolecular weight:501.02Benzamidine
CAS:Benzamidine is a reversible competitive inhibitor of trypsin with a Ki of 19 μM. It also exhibits inhibitory activity on an enzyme in homogenized porcine sperm acrosome, with a Ki of 4 μM.Formula:C7H8N2Color and Shape:SolidMolecular weight:120.15

