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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 987 products of "Proteases/Proteasome"

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  • AR-H067637

    CAS:
    AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.
    Formula:C21H21ClF2N4O4
    Color and Shape:Solid
    Molecular weight:466.87

    Ref: TM-T26657

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  • Enzyme-IN-1

    CAS:
    Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。
    Formula:C36H50N4O7
    Color and Shape:Solid
    Molecular weight:650.8

    Ref: TM-T74878

    5mg
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    50mg
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  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid

    Ref: TM-T82510

    5mg
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    50mg
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  • Cerpegin

    CAS:
    Cerpegin, a pyridine ketone fused c-lactone, acts as an inhibitor of the 20S proteasome. It possesses pharmacological properties as a neuropsychiatric sedative, anti-inflammatory, analgesic, and exhibits anti-ulcer activity.
    Formula:C10H11NO3
    Color and Shape:Solid
    Molecular weight:193.2

    Ref: TM-TN8223

    10mg
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  • Tiprelestat

    CAS:
    Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.
    Formula:C254H416N72O75S10
    Color and Shape:Solid
    Molecular weight:5999.09

    Ref: TM-T73657

    5mg
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    50mg
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  • ZG36


    ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial
    Color and Shape:Odour Solid

    Ref: TM-T80737

    5mg
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    50mg
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  • Alisporivir

    CAS:
    Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64

    Ref: TM-T14180

    1mg
    177.00€
    5mg
    447.00€
    10mg
    650.00€
    25mg
    1,018.00€
    50mg
    1,369.00€
  • Rivulariapeptolides 988


    Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).
    Formula:C50H68N8O13
    Color and Shape:Solid
    Molecular weight:989.12

    Ref: TM-T75651

    5mg
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    50mg
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  • Carboxypeptidase C

    CAS:
    Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.
    Color and Shape:Solid

    Ref: TM-T76168

    5mg
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    50mg
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  • Micropeptin 478A

    CAS:
    Micropeptin 478A is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
    Formula:C40H62ClN9O15S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:976.49

    Ref: TM-T25810

    25mg
    1,369.00€
  • Sofosbuvir impurity I


    Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C21H27FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.43

    Ref: TM-T12964

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  • Sofosbuvir impurity K

    CAS:
    Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H29ClN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:545.91

    Ref: TM-T12966

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  • Cajaninstilbene acid

    CAS:
    Cajaninstilbene acid is a useful organic compound for research related to life sciences. The catalog number is T124035 and the CAS number is 87402-84-4.
    Formula:C21H22O4
    Color and Shape:Solid
    Molecular weight:338.403

    Ref: TM-T124035

    1mg
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    5mg
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  • MMP-12 Inhibitor

    CAS:

    MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.

    Formula:C19H20N2O7S
    Purity:97.51% - 99.96%
    Color and Shape:Soild
    Molecular weight:420.44

    Ref: TM-T60083

    1mg
    185.00€
    5mg
    425.00€
    10mg
    642.00€
    25mg
    1,096.00€
    50mg
    1,643.00€
    100mg
    2,465.00€
  • Isoleucylvaline

    CAS:
    Isoleucylvaline is a dipeptide.
    Formula:C11H22N2O3
    Color and Shape:Solid
    Molecular weight:230.30

    Ref: TM-T32214

    100mg
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    500mg
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  • GCPII-IN-1

    CAS:

    GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.

    Formula:C12H21N3O7
    Color and Shape:Solid
    Molecular weight:319.314

    Ref: TM-T38420

    5mg
    922.00€
  • N-CBZ-Phe-Arg-AMC

    CAS:
    Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.
    Formula:C33H36N6O6
    Purity:98%
    Color and Shape:White To Off-White Powder
    Molecular weight:612.68

    Ref: TM-TP1013

    100mg
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    500mg
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  • Fibrinopeptide B, human

    CAS:
    Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.
    Formula:C66H93N19O25
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1552.56

    Ref: TM-TP1163

    1mg
    74.00€
    5mg
    268.00€
    10mg
    462.00€
  • Chetoseminudin B

    CAS:
    Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].
    Formula:C17H21N3O3S2
    Color and Shape:Solid
    Molecular weight:379.5

    Ref: TM-T75471

    5mg
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    50mg
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  • Ellipyrone A


    Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53

    Ref: TM-T75492

    5mg
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    50mg
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  • Ac-DEMEEC-OH

    CAS:
    Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.
    Formula:C29H44N6O16S2
    Color and Shape:Solid
    Molecular weight:796.82

    Ref: TM-TP2848

    10mg
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  • NS5A-IN-1


    NS5A-IN-1 is a proagent of the HCV NS5A inhibitor Pibrentasvir (ABT-530).
    Formula:C72H86F5N10O14P
    Color and Shape:Solid
    Molecular weight:1441.48

    Ref: TM-T74403

    5mg
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    50mg
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  • Nostopeptin B

    CAS:
    Nostopeptin B is an inhibitor of elastase.
    Formula:C46H70N8O12
    Color and Shape:Solid
    Molecular weight:927.11

    Ref: TM-T25880

    25mg
    1,444.00€
  • Sofigatran

    CAS:
    Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.
    Formula:C24H44N4O4S
    Color and Shape:Solid
    Molecular weight:484.7

    Ref: TM-T39310

    5mg
    873.00€
  • MMP-9-IN-6

    CAS:
    MMP-9-IN-6: MMP-9 inhibitor, IC50 of 50 µM, anti-ulcer, potential anti-tumor, for tissue repair studies.
    Formula:C25H19NO2
    Purity:98.96%
    Color and Shape:Soild
    Molecular weight:365.42

    Ref: TM-T77617

    1mg
    70.00€
    5mg
    138.00€
    10mg
    195.00€
    25mg
    309.00€
    50mg
    408.00€
    100mg
    562.00€
    200mg
    743.00€
  • AL-611

    CAS:

    AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).

    Formula:C25H33F2N6O8P
    Color and Shape:Solid
    Molecular weight:614.544

    Ref: TM-T39082

    5mg
    922.00€
  • L 659286

    CAS:
    L 659286 is one kind of cephalosporin derivative.
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51

    Ref: TM-T32460

    25mg
    1,369.00€
  • Talabostat isomer mesylate


    Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).
    Formula:C10H23BN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.18

    Ref: TM-T13069

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  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
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    50mg
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  • Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

    CAS:
    Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).
    Formula:C49H68N14O12S
    Color and Shape:Solid
    Molecular weight:1077.22

    Ref: TM-T36360

    1mg
    384.00€
  • Dutogliptin

    CAS:
    Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C10H20BN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.10

    Ref: TM-T11128

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  • Ac-PLVE-FMK

    CAS:
    Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].
    Formula:C25H41FN4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.61

    Ref: TM-T78185

    5mg
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    50mg
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  • Acetyl-Calpastatin(184-210)(human)

    CAS:
    Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.
    Formula:C142H230N36O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3177.65

    Ref: TM-TP2056

    1mg
    1,378.00€
  • TP0597850

    CAS:
    TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].
    Formula:C41H57N9O13S
    Color and Shape:Solid
    Molecular weight:916.01

    Ref: TM-T74714

    5mg
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    50mg
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  • AP-C2

    CAS:
    AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
    Formula:C18H16N4S
    Purity:99.99%
    Color and Shape:Soild
    Molecular weight:320.41

    Ref: TM-T77570

    2mg
    38.00€
    5mg
    59.00€
    10mg
    82.00€
    25mg
    148.00€
    50mg
    245.00€
    100mg
    427.00€
    200mg
    577.00€
  • (-)-Taxifolin

    CAS:
    (-)-Taxifolin, less active enantiomer with anti-tyrosinase, collagenase inhibition (IC50 = 193.3 μM), antifibrotic, antioxidant properties.
    Formula:C15H12O7
    Color and Shape:Solid
    Molecular weight:304.25

    Ref: TM-T38497

    25mg
    1,369.00€
  • Tyrosinase-IN-32


    Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.
    Formula:C15H19NO3
    Color and Shape:Solid
    Molecular weight:261.32

    Ref: TM-TN8160

    10mg
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  • Linagliptin Methyldimer

    CAS:
    Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
    Formula:C50H56N16O4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:945.08

    Ref: TM-T67852

    1mg
    109.00€
    2mg
    158.00€
    5mg
    260.00€
    10mg
    385.00€
    25mg
    628.00€
    50mg
    872.00€
    100mg
    1,153.00€
  • C-telopeptide

    CAS:
    C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.
    Formula:C34H56N14O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:868.9

    Ref: TM-TP1779

    1mg
    109.00€
    5mg
    424.00€
    10mg
    720.00€
  • Aristololactam IIIa

    CAS:
    Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.
    Formula:C16H9NO4
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T75619

    5mg
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    50mg
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  • Histargin

    CAS:
    Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.
    Formula:C14H25N7O4
    Color and Shape:Solid
    Molecular weight:355.39

    Ref: TM-T25504

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  • Rivulariapeptolides 1121


    Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).
    Formula:C56H83N9O15
    Color and Shape:Solid
    Molecular weight:1122.31

    Ref: TM-T75650

    5mg
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    50mg
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  • KKI-5

    CAS:

    KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.

    Formula:C35H55N11O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:773.88

    Ref: TM-TP1792

    1mg
    64.00€
    5mg
    172.00€
    10mg
    299.00€
  • Zetomipzomib maleate

    CAS:
    Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.
    Formula:C34H46N4O12
    Color and Shape:Solid
    Molecular weight:702.758

    Ref: TM-T39653

    5mg
    1,341.00€
  • HCVP-IN-1

    CAS:
    HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.
    Formula:C30H34FN5O3
    Color and Shape:Solid
    Molecular weight:531.632

    Ref: TM-T41002

    5mg
    873.00€
  • Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

    CAS:
    Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect
    Formula:C47H64N14O10
    Color and Shape:Solid
    Molecular weight:985.1

    Ref: TM-T76347

    5mg
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    50mg
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  • NVP-DPP728 dihydrochloride

    CAS:
    NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27

    Ref: TM-T39481

    25mg
    1,369.00€
  • Pirmitegravir

    CAS:

    Pirmitegravir (STP0404) is a potent ALLINI, blocks LEDGF/p75 site, shows antiviral action against HIV.

    Formula:C27H31ClN4O3
    Purity:99.79% - 99.79%
    Color and Shape:Solid
    Molecular weight:495.01

    Ref: TM-T39755

    1mg
    134.00€
    5mg
    321.00€
    10mg
    518.00€
    25mg
    1,035.00€
    50mg
    1,700.00€
    100mg
    2,270.00€
  • PPACK II

    CAS:
    PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .
    Formula:C25H33ClN6O3
    Color and Shape:Solid
    Molecular weight:501.02

    Ref: TM-T73863

    5mg
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    50mg
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  • Benzamidine

    CAS:
    Benzamidine is a reversible competitive inhibitor of trypsin with a Ki of 19 μM. It also exhibits inhibitory activity on an enzyme in homogenized porcine sperm acrosome, with a Ki of 4 μM.
    Formula:C7H8N2
    Color and Shape:Solid
    Molecular weight:120.15

    Ref: TM-T203133

    10mg
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