
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
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Found 1045 products of "Proteases/Proteasome"
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PR 39 (porcine) acetate
<p>PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.</p>Purity:98%Color and Shape:LiquidMolecular weight:N/A6-Acetylnimbandiol
CAS:<p>6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.</p>Formula:C28H34O8Color and Shape:SolidMolecular weight:498.56Zetomipzomib maleate
CAS:<p>Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.</p>Formula:C34H46N4O12Color and Shape:SolidMolecular weight:702.758Rivulariapeptolides 988
<p>Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).</p>Formula:C50H68N8O13Color and Shape:SolidMolecular weight:989.12L 659286
CAS:<p>L 659286 is one kind of cephalosporin derivative.</p>Formula:C17H21N5O7S2Color and Shape:SolidMolecular weight:471.51Pseudostellarin G
CAS:<p>Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.</p>Formula:C42H56N8O9Color and Shape:SolidMolecular weight:816.94CRA-2059
CAS:<p>CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.</p>Formula:C34H46N12O8Purity:97.68%Color and Shape:SolidMolecular weight:750.818Ellipyrone A
<p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>Formula:C25H34O8Color and Shape:SolidMolecular weight:462.53Leptosin D
CAS:<p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>Formula:C25H24N4O3S2Color and Shape:SolidMolecular weight:492.61Emtricitabine S-oxide
CAS:<p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>Formula:C8H10FN3O4SPurity:98%Color and Shape:SolidMolecular weight:263.25Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:<p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>Formula:C47H64N14O10Color and Shape:SolidMolecular weight:985.1Peptide 74
CAS:<p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>Formula:C62H107N23O20S2Purity:98%Color and Shape:SolidMolecular weight:1558.79Fotagliptin
CAS:<p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>Formula:C17H19FN6OColor and Shape:SolidMolecular weight:342.37Rivulariapeptolides 1121
<p>Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).</p>Formula:C56H83N9O15Color and Shape:SolidMolecular weight:1122.31E-64d [for Biochemical Research]
CAS:Formula:C17H30N2O5Purity:>95.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:342.44CTS-1027
CAS:<p>CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.</p>Formula:C19H20ClNO6SColor and Shape:SolidMolecular weight:425.88Tenofovir hydrate
CAS:<p>Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.</p>Formula:C9H16N5O5PPurity:99.63%Color and Shape:SolidMolecular weight:305.23Ilomastat
CAS:Formula:C20H28N4O4Purity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:388.47S-Methylglutathione
CAS:<p>S-Methylglutathione (S-Methyl glutathione) is a 1-chloro-2,4-dinitrobenzene coupling inhibitor, an XOCl scavenger, and inhibitor of glyoxalase 1.</p>Formula:C11H19N3O6SPurity:98%Color and Shape:SolidMolecular weight:321.35Retagliptin
CAS:<p>Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.</p>Formula:C19H18F6N4O3Color and Shape:SolidMolecular weight:464.36PSI-6206 13C,d3
CAS:<p>PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.</p>Formula:C10H13FN2O5Purity:98%Color and Shape:SolidMolecular weight:264.23Tripeptide-32
CAS:<p>Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].</p>Formula:C12H22N4O5Purity:98%Color and Shape:SolidMolecular weight:302.33Glutaminase-IN-3
CAS:<p>Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.</p>Formula:C19H19F3N6O2SPurity:98.51%Color and Shape:SolidMolecular weight:452.45MMP-8 Inhibitor I
CAS:<p>MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.</p>Formula:C17H18N2O5SColor and Shape:SolidMolecular weight:362.4Tilpisertib
CAS:<p>Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).</p>Formula:C33H33ClN8OColor and Shape:SolidMolecular weight:593.13Teneligliptin hydrobromide hydrate
CAS:<p>Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.</p>Formula:C22H33BrN6O2SColor and Shape:SolidMolecular weight:525.51Sitagliptin fenilalanil
CAS:<p>Sitagliptin fenilalanil is a dipeptidyl aminopeptidase (DPP-4) inhibitor.</p>Formula:C25H24F6N6O2Color and Shape:SolidMolecular weight:554.49PKSI-527
CAS:<p>PKSI-527 inhibits plasma kallikrein (Ki=0.81μM), selective vs. glandular kallikrein/thrombin/urokinase/Xa, reduces bradykinin, affects clotting times.</p>Formula:C25H32ClN3O4Color and Shape:SolidMolecular weight:473.99H-Arg-4MβNA
CAS:<p>H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.</p>Formula:C17H23N5O2Purity:99.98%Color and Shape:SolidMolecular weight:329.4BAY-677
CAS:<p>BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.</p>Formula:C20H15F3N4O2Color and Shape:SolidMolecular weight:400.355-Amino-8-hydroxyquinoline
CAS:<p>5-Amino-8-hydroxyquinoline(5A8HQ),Proteasome inhibitor. Potential anticancer agent.</p>Formula:C9H8N2OPurity:99.69%Color and Shape:SolidMolecular weight:160.176-Chloro-7-deazapurine-2F-β-D-arabinofuranose
CAS:<p>6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.</p>Formula:C11H11ClFN3O3Color and Shape:SolidMolecular weight:287.67(Arg)9
CAS:<p>(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).</p>Formula:C54H110N36O10Color and Shape:SolidMolecular weight:1423.69Ubenimex Hydrochloride [for Biochemical Research]
CAS:Formula:C16H24N2O4·HClPurity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:344.84Dabigatran ethyl ester
CAS:<p>Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.</p>Formula:C27H29N7O3Purity:99.98%Color and Shape:SolidMolecular weight:499.56Saquinavir mesylate
CAS:<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Formula:C39H54N6O8SPurity:99.19%Color and Shape:White Or Pale Yellow PowderMolecular weight:766.9Teneligliptin D8
CAS:<p>Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.</p>Formula:C22H30N6OSPurity:98%Color and Shape:SolidMolecular weight:434.63PD-166793
CAS:<p>PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.</p>Formula:C17H18BrNO4SPurity:99.86%Color and Shape:SolidMolecular weight:412.3Tomeglovir
CAS:<p>Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).</p>Formula:C23H27N3O4SPurity:98%Color and Shape:SolidMolecular weight:441.54DMP 777
CAS:<p>DMP 777 is an orally active inhibitor of human leukocyte elastase.</p>Formula:C31H40N4O6Color and Shape:SolidMolecular weight:564.67Thrombin inhibitor 5
CAS:<p>Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.</p>Formula:C11H9FN4O3Purity:99.58%Color and Shape:SolidMolecular weight:264.21H-Pro-Lys-OH TFA
<p>H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.</p>Formula:C13H22F3N3O5Color and Shape:SolidMolecular weight:357.332'-β-C-Ethynyladenosine
CAS:<p>2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.</p>Formula:C12H13N5O4Color and Shape:SolidMolecular weight:291.26Sivelestat Sodium Tetrahydrate
CAS:Formula:C20H21N2NaO7S·4H2OPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:528.50Urokinase
CAS:<p>Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.</p>Color and Shape:SolidPentosan Polysulfate Sodium (W/W 43%)
CAS:<p>Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.</p>Purity:98%Color and Shape:SolidMolecular weight:N/AAnguizole
CAS:<p>Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B.</p>Formula:C17H11ClF2N4O2SColor and Shape:SolidMolecular weight:408.81Pepstatin A
CAS:Formula:C34H63N5O9Purity:>90.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:685.90(-)-Gallocatechin Gallate
CAS:Formula:C22H18O11Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:458.38Tanaproget
CAS:<p>Tanaproget is an orally available, high-affinity, non-steroidal progesterone receptor (PR) agonist with an IC50 of 1.7 nM for hPR.</p>Formula:C16H15N3OSPurity:98%Color and Shape:SolidMolecular weight:297.38


