
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(505 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 987 products of "Proteases/Proteasome"
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Z-FG-NHO-Bz
CAS:Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].Formula:C26H25N3O6Color and Shape:SolidMolecular weight:475.49LMP7/LMP2-IN-1
CAS:LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.Formula:C16H27BN4O3Color and Shape:SoildMolecular weight:334.22Ac-Phe-Gly-pNA
CAS:Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .Formula:C19H20N4O5Color and Shape:SolidMolecular weight:384.39FFAGLDD
"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."Formula:C37H49N7O12Purity:98%Color and Shape:SolidMolecular weight:783.82H-Pro-Lys-OH TFA
H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.Formula:C13H22F3N3O5Color and Shape:SolidMolecular weight:357.33Diprotin A TFA
CAS:Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).Formula:C19H32F3N3O6Color and Shape:SolidMolecular weight:455.47Arabinosylhypoxanthine
CAS:Arabinosylhypoxanthine inhibits Ns5b polymerase in hepatitis C virus and can be used in biochemical experiments and organic synthesis.Formula:C10H12N4O5Purity:99.71%Color and Shape:SolidMolecular weight:268.232'-β-C-Ethynyladenosine
CAS:2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.Formula:C12H13N5O4Color and Shape:SolidMolecular weight:291.26Saxagliptin hydrochloride
CAS:Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.Formula:C18H26ClN3O2Color and Shape:SolidMolecular weight:351.87Anguizole
CAS:Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B.Formula:C17H11ClF2N4O2SColor and Shape:SolidMolecular weight:408.81Sivelestat Sodium Tetrahydrate
CAS:Formula:C20H21N2NaO7S·4H2OPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:528.50Tanaproget
CAS:Tanaproget is an orally available, high-affinity, non-steroidal progesterone receptor (PR) agonist with an IC50 of 1.7 nM for hPR.Formula:C16H15N3OSPurity:98%Color and Shape:SolidMolecular weight:297.38Ubenimex
CAS:Formula:C16H24N2O4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:308.38Alogliptin (13CD3)
CAS:Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.Formula:C18H21N5O2Purity:98%Color and Shape:SolidMolecular weight:343.4(-)-Gallocatechin Gallate
CAS:Formula:C22H18O11Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:458.38Retagliptin
CAS:Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.Formula:C19H18F6N4O3Color and Shape:SolidMolecular weight:464.36Urokinase
CAS:Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.Color and Shape:SolidCTS-1027
CAS:CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.Formula:C19H20ClNO6SColor and Shape:SolidMolecular weight:425.88LN5P45
LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1Formula:C13H15ClN2O2Color and Shape:SolidMolecular weight:266.726-Chloro-7-deazapurine-2F-β-D-arabinofuranose
CAS:6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.Formula:C11H11ClFN3O3Color and Shape:SolidMolecular weight:287.67Ref: TM-TNU0055
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire500mgTo inquireE-64d [for Biochemical Research]
CAS:Formula:C17H30N2O5Purity:>95.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:342.44MMP-8 Inhibitor I
CAS:MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.Formula:C17H18N2O5SColor and Shape:SolidMolecular weight:362.4PSI-6206 13C,d3
CAS:PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.
Formula:C10H13FN2O5Purity:98%Color and Shape:SolidMolecular weight:264.23Sitagliptin fenilalanil
CAS:Sitagliptin fenilalanil is a dipeptidyl aminopeptidase (DPP-4) inhibitor.Formula:C25H24F6N6O2Color and Shape:SolidMolecular weight:554.49Ubenimex Hydrochloride [for Biochemical Research]
CAS:Formula:C16H24N2O4·HClPurity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:344.84PKSI-527
CAS:PKSI-527 inhibits plasma kallikrein (Ki=0.81μM), selective vs. glandular kallikrein/thrombin/urokinase/Xa, reduces bradykinin, affects clotting times.Formula:C25H32ClN3O4Color and Shape:SolidMolecular weight:473.99Glutaminase-IN-3
CAS:Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.Formula:C19H19F3N6O2SPurity:98.51%Color and Shape:SolidMolecular weight:452.45Ilomastat
CAS:Formula:C20H28N4O4Purity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:388.47Tomeglovir
CAS:Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).Formula:C23H27N3O4SPurity:98%Color and Shape:SolidMolecular weight:441.54Thrombin inhibitor 5
CAS:Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.Formula:C11H9FN4O3Purity:99.58%Color and Shape:SolidMolecular weight:264.21Ref: TM-T9845
2mg35.00€5mg56.00€10mg86.00€25mg154.00€50mg224.00€100mg320.00€200mg434.00€1mL*10mM (DMSO)55.00€Tilpisertib
CAS:Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).Formula:C33H33ClN8OColor and Shape:SolidMolecular weight:593.13Dabigatran ethyl ester
CAS:Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formula:C27H29N7O3Purity:99.98%Color and Shape:SolidMolecular weight:499.56BAY-677
CAS:BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.Formula:C20H15F3N4O2Color and Shape:SolidMolecular weight:400.35PD-166793
CAS:PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.Formula:C17H18BrNO4SPurity:99.86%Color and Shape:SolidMolecular weight:412.3Ref: TM-T20563
5mg42.00€10mg60.00€25mg112.00€50mg175.00€100mg261.00€200mg368.00€1mL*10mM (DMSO)46.00€H-Arg-4MβNA
CAS:H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.Formula:C17H23N5O2Purity:99.98%Color and Shape:SolidMolecular weight:329.4(Arg)9
CAS:(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).Formula:C54H110N36O10Color and Shape:SolidMolecular weight:1423.69DMP 777
CAS:DMP 777 is an orally active inhibitor of human leukocyte elastase.Formula:C31H40N4O6Color and Shape:SolidMolecular weight:564.67ML-345
CAS:ML-345, Selective IDE inhibitor (IC50=188 nM) targeting Cys819, for type 2 diabetes and Alzheimer's research.Formula:C21H22FN3O5S2Purity:99.21%Color and Shape:SolidMolecular weight:479.55Ref: TM-T35802
1mg39.00€5mg84.00€10mg120.00€25mg197.00€50mgTo inquire100mg434.00€1mL*10mM (DMSO)To inquireTeneligliptin D8
CAS:Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.Formula:C22H30N6OSPurity:98%Color and Shape:SolidMolecular weight:434.635-Amino-8-hydroxyquinoline
CAS:5-Amino-8-hydroxyquinoline(5A8HQ),Proteasome inhibitor. Potential anticancer agent.Formula:C9H8N2OPurity:99.69%Color and Shape:SolidMolecular weight:160.17Trisodium Hydrogen Ethylenediaminetetraacetate Hydrate [for Biochemical Research]
CAS:Formula:C10H13N2Na3O8·xH2OPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:358.19 (as Anhydrous)Pepstatin A
CAS:Formula:C34H63N5O9Purity:>90.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:685.904-Butylresorcinol
CAS:4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Formula:C10H14O2Purity:99.48% - ≥95%Color and Shape:Light Beige Solid PowderMolecular weight:166.22Anagliptin hydrochloride
CAS:Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.Formula:C19H26ClN7O2Color and Shape:SolidMolecular weight:419.91GW280264X
CAS:GW280264X (Carbamic acid) is an inhibitor of ADAM17 .Formula:C28H41N5O6SPurity:99.51%Color and Shape:SolidMolecular weight:575.72Ref: TM-T8961
1mg156.00€5mg319.00€10mg477.00€25mg773.00€50mg1,063.00€100mg1,431.00€1mL*10mM (DMSO)404.00€UAMC00039 dihydrochloride
CAS:UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.Formula:C16H26Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:382.76PSI-6206
CAS:PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.Formula:C10H13FN2O5Purity:98% - 99.79%Color and Shape:SolidMolecular weight:260.22Daclatasvir dihydrochloride
CAS:Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.Formula:C40H52Cl2N8O6Purity:99.67%Color and Shape:SolidMolecular weight:811.8Ref: TM-T1786
1g230.00€5mg39.00€10mg48.00€25mg57.00€50mg67.00€100mg77.00€500mg161.00€1mL*10mM (DMSO)49.00€Ledipasvir hydrochloride
CAS:Ledipasvir hydrochloride, a hepatitis C NS5A inhibitor, has EC50 of 34 pM (1a) and 4 pM (1b), also inhibits SARS-CoV 3CL pro (IC50 1.62 µM).Formula:C49H55ClF2N8O6Color and Shape:SolidMolecular weight:925.46T-26c
CAS:T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).Formula:C24H21N3O6SPurity:>99.99%Color and Shape:SolidMolecular weight:479.51Ref: TM-T5361
1mg48.00€2mg64.00€5mg96.00€10mg153.00€25mg250.00€50mg424.00€100mg613.00€1mL*10mM (DMSO)97.00€


