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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • PR 39 (porcine) acetate


    <p>PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.</p>
    Purity:98%
    Color and Shape:Liquid
    Molecular weight:N/A
  • 6-Acetylnimbandiol

    CAS:
    <p>6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.</p>
    Formula:C28H34O8
    Color and Shape:Solid
    Molecular weight:498.56
  • Zetomipzomib maleate

    CAS:
    <p>Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.</p>
    Formula:C34H46N4O12
    Color and Shape:Solid
    Molecular weight:702.758
  • Rivulariapeptolides 988


    <p>Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).</p>
    Formula:C50H68N8O13
    Color and Shape:Solid
    Molecular weight:989.12
  • L 659286

    CAS:
    <p>L 659286 is one kind of cephalosporin derivative.</p>
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51
  • Pseudostellarin G

    CAS:
    <p>Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.</p>
    Formula:C42H56N8O9
    Color and Shape:Solid
    Molecular weight:816.94
  • CRA-2059

    CAS:
    <p>CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.</p>
    Formula:C34H46N12O8
    Purity:97.68%
    Color and Shape:Solid
    Molecular weight:750.818
  • Ellipyrone A


    <p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53
  • Leptosin D

    CAS:
    <p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>
    Formula:C25H24N4O3S2
    Color and Shape:Solid
    Molecular weight:492.61
  • Emtricitabine S-oxide

    CAS:
    <p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>
    Formula:C8H10FN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:263.25
  • Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

    CAS:
    <p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>
    Formula:C47H64N14O10
    Color and Shape:Solid
    Molecular weight:985.1
  • Peptide 74

    CAS:
    <p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>
    Formula:C62H107N23O20S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1558.79
  • Fotagliptin

    CAS:
    <p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37
  • Rivulariapeptolides 1121


    <p>Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).</p>
    Formula:C56H83N9O15
    Color and Shape:Solid
    Molecular weight:1122.31
  • E-64d [for Biochemical Research]

    CAS:
    Formula:C17H30N2O5
    Purity:>95.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:342.44

    Ref: 3B-E1337

    5mg
    127.00€
    25mg
    402.00€
  • CTS-1027

    CAS:
    <p>CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has &gt; 1,000 fold selectivity over MMP1.</p>
    Formula:C19H20ClNO6S
    Color and Shape:Solid
    Molecular weight:425.88
  • Tenofovir hydrate

    CAS:
    <p>Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.</p>
    Formula:C9H16N5O5P
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:305.23
  • Ilomastat

    CAS:
    Formula:C20H28N4O4
    Purity:>95.0%(HPLC)(qNMR)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:388.47

    Ref: 3B-I1202

    10mg
    189.00€
  • S-Methylglutathione

    CAS:
    <p>S-Methylglutathione (S-Methyl glutathione) is a 1-chloro-2,4-dinitrobenzene coupling inhibitor, an XOCl scavenger, and inhibitor of glyoxalase 1.</p>
    Formula:C11H19N3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.35
  • Retagliptin

    CAS:
    <p>Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.</p>
    Formula:C19H18F6N4O3
    Color and Shape:Solid
    Molecular weight:464.36
  • PSI-6206 13C,d3

    CAS:
    <p>PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.</p>
    Formula:C10H13FN2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:264.23
  • Tripeptide-32

    CAS:
    <p>Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].</p>
    Formula:C12H22N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:302.33
  • Glutaminase-IN-3

    CAS:
    <p>Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.</p>
    Formula:C19H19F3N6O2S
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:452.45
  • MMP-8 Inhibitor I

    CAS:
    <p>MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.</p>
    Formula:C17H18N2O5S
    Color and Shape:Solid
    Molecular weight:362.4
  • Tilpisertib

    CAS:
    <p>Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).</p>
    Formula:C33H33ClN8O
    Color and Shape:Solid
    Molecular weight:593.13
  • Teneligliptin hydrobromide hydrate

    CAS:
    <p>Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.</p>
    Formula:C22H33BrN6O2S
    Color and Shape:Solid
    Molecular weight:525.51
  • Sitagliptin fenilalanil

    CAS:
    <p>Sitagliptin fenilalanil is a dipeptidyl aminopeptidase (DPP-4) inhibitor.</p>
    Formula:C25H24F6N6O2
    Color and Shape:Solid
    Molecular weight:554.49
  • PKSI-527

    CAS:
    <p>PKSI-527 inhibits plasma kallikrein (Ki=0.81μM), selective vs. glandular kallikrein/thrombin/urokinase/Xa, reduces bradykinin, affects clotting times.</p>
    Formula:C25H32ClN3O4
    Color and Shape:Solid
    Molecular weight:473.99
  • H-Arg-4MβNA

    CAS:
    <p>H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.</p>
    Formula:C17H23N5O2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:329.4
  • BAY-677

    CAS:
    <p>BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.</p>
    Formula:C20H15F3N4O2
    Color and Shape:Solid
    Molecular weight:400.35
  • 5-Amino-8-hydroxyquinoline

    CAS:
    <p>5-Amino-8-hydroxyquinoline(5A8HQ),Proteasome inhibitor. Potential anticancer agent.</p>
    Formula:C9H8N2O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:160.17
  • 6-Chloro-7-deazapurine-2F-β-D-arabinofuranose

    CAS:
    <p>6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.</p>
    Formula:C11H11ClFN3O3
    Color and Shape:Solid
    Molecular weight:287.67
  • (Arg)9

    CAS:
    <p>(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).</p>
    Formula:C54H110N36O10
    Color and Shape:Solid
    Molecular weight:1423.69
  • Ubenimex Hydrochloride [for Biochemical Research]

    CAS:
    Formula:C16H24N2O4·HCl
    Purity:>97.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:344.84

    Ref: 3B-B4000

    25mg
    196.00€
  • Dabigatran ethyl ester

    CAS:
    <p>Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.</p>
    Formula:C27H29N7O3
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:499.56
  • Saquinavir mesylate

    CAS:
    <p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>
    Formula:C39H54N6O8S
    Purity:99.19%
    Color and Shape:White Or Pale Yellow Powder
    Molecular weight:766.9
  • Teneligliptin D8

    CAS:
    <p>Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.</p>
    Formula:C22H30N6OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:434.63
  • PD-166793

    CAS:
    <p>PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.</p>
    Formula:C17H18BrNO4S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:412.3
  • Tomeglovir

    CAS:
    <p>Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).</p>
    Formula:C23H27N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:441.54
  • DMP 777

    CAS:
    <p>DMP 777 is an orally active inhibitor of human leukocyte elastase.</p>
    Formula:C31H40N4O6
    Color and Shape:Solid
    Molecular weight:564.67
  • Thrombin inhibitor 5

    CAS:
    <p>Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.</p>
    Formula:C11H9FN4O3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:264.21
  • H-Pro-Lys-OH TFA


    <p>H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.</p>
    Formula:C13H22F3N3O5
    Color and Shape:Solid
    Molecular weight:357.33
  • 2'-β-C-Ethynyladenosine

    CAS:
    <p>2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.</p>
    Formula:C12H13N5O4
    Color and Shape:Solid
    Molecular weight:291.26
  • Sivelestat Sodium Tetrahydrate

    CAS:
    Formula:C20H21N2NaO7S·4H2O
    Purity:>95.0%(T)(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:528.50

    Ref: 3B-I1240

    25mg
    318.00€
  • Urokinase

    CAS:
    <p>Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.</p>
    Color and Shape:Solid
  • Pentosan Polysulfate Sodium (W/W 43%)

    CAS:
    <p>Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • Anguizole

    CAS:
    <p>Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B.</p>
    Formula:C17H11ClF2N4O2S
    Color and Shape:Solid
    Molecular weight:408.81
  • Pepstatin A

    CAS:
    Formula:C34H63N5O9
    Purity:>90.0%(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:685.90

    Ref: 3B-P3041

    10mg
    102.00€
  • (-)-Gallocatechin Gallate

    CAS:
    Formula:C22H18O11
    Purity:>95.0%(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:458.38

    Ref: 3B-G0628

    25mg
    290.00€
  • Tanaproget

    CAS:
    <p>Tanaproget is an orally available, high-affinity, non-steroidal progesterone receptor (PR) agonist with an IC50 of 1.7 nM for hPR.</p>
    Formula:C16H15N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.38