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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 987 products of "Proteases/Proteasome"

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  • Z-FG-NHO-Bz

    CAS:
    Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].
    Formula:C26H25N3O6
    Color and Shape:Solid
    Molecular weight:475.49

    Ref: TM-T80740

    5mg
    To inquire
    50mg
    To inquire
  • LMP7/LMP2-IN-1

    CAS:
    LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.
    Formula:C16H27BN4O3
    Color and Shape:Soild
    Molecular weight:334.22

    Ref: TM-T88971

    10mg
    To inquire
    50mg
    To inquire
  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
    To inquire
    50mg
    To inquire
  • FFAGLDD


    "FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."
    Formula:C37H49N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:783.82

    Ref: TM-TP1545

    2mg
    71.00€
    5mg
    92.00€
    10mg
    131.00€
    25mg
    229.00€
    50mg
    343.00€
    100mg
    517.00€
  • H-Pro-Lys-OH TFA


    H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.
    Formula:C13H22F3N3O5
    Color and Shape:Solid
    Molecular weight:357.33

    Ref: TM-TP3141

    1mg
    37.00€
    5mg
    To inquire
  • Diprotin A TFA

    CAS:
    Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).
    Formula:C19H32F3N3O6
    Color and Shape:Solid
    Molecular weight:455.47

    Ref: TM-T11049

    2mg
    51.00€
  • Arabinosylhypoxanthine

    CAS:
    Arabinosylhypoxanthine inhibits Ns5b polymerase in hepatitis C virus and can be used in biochemical experiments and organic synthesis.
    Formula:C10H12N4O5
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:268.23

    Ref: TM-TNU1625

    5mg
    46.00€
    10mg
    58.00€
    25mg
    95.00€
    50mg
    124.00€
    100mg
    178.00€
    200mg
    264.00€
  • 2'-β-C-Ethynyladenosine

    CAS:
    2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.
    Formula:C12H13N5O4
    Color and Shape:Solid
    Molecular weight:291.26

    Ref: TM-TNU0474

    1mg
    190.00€
    5mg
    471.00€
  • Saxagliptin hydrochloride

    CAS:
    Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.
    Formula:C18H26ClN3O2
    Color and Shape:Solid
    Molecular weight:351.87

    Ref: TM-T6203L

    5mg
    873.00€
  • Anguizole

    CAS:
    Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B.
    Formula:C17H11ClF2N4O2S
    Color and Shape:Solid
    Molecular weight:408.81

    Ref: TM-T14289

    2mg
    62.00€
  • Sivelestat Sodium Tetrahydrate

    CAS:
    Formula:C20H21N2NaO7S·4H2O
    Purity:>95.0%(T)(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:528.50

    Ref: 3B-I1240

    25mg
    227.00€
  • Tanaproget

    CAS:
    Tanaproget is an orally available, high-affinity, non-steroidal progesterone receptor (PR) agonist with an IC50 of 1.7 nM for hPR.
    Formula:C16H15N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.38

    Ref: TM-T16985

    1mg
    47.00€
    5mg
    To inquire
    10mg
    To inquire
    1mL*10mM (DMSO)
    101.00€
  • Ubenimex

    CAS:
    Formula:C16H24N2O4
    Purity:>98.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:308.38

    Ref: 3B-U0111

    1g
    314.00€
    250mg
    103.00€
  • Alogliptin (13CD3)

    CAS:
    Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.
    Formula:C18H21N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:343.4

    Ref: TM-T10288

    1mg
    513.00€
    5mg
    1,539.00€
    10mg
    2,565.00€
    25mg
    4,753.00€
  • (-)-Gallocatechin Gallate

    CAS:
    Formula:C22H18O11
    Purity:>95.0%(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:458.38

    Ref: 3B-G0628

    25mg
    226.00€
  • Retagliptin

    CAS:
    Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.
    Formula:C19H18F6N4O3
    Color and Shape:Solid
    Molecular weight:464.36

    Ref: TM-T28520

    2mg
    77.00€
  • Urokinase

    CAS:
    Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.
    Color and Shape:Solid

    Ref: TM-T73701

    1mg
    166.00€
    5mg
    402.00€
    10mg
    565.00€
    25mg
    1,235.00€
  • CTS-1027

    CAS:
    CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.
    Formula:C19H20ClNO6S
    Color and Shape:Solid
    Molecular weight:425.88

    Ref: TM-T15015

    2mg
    90.00€
  • LN5P45


    LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1
    Formula:C13H15ClN2O2
    Color and Shape:Solid
    Molecular weight:266.72

    Ref: TM-T78826

    1mg
    180.00€
  • 6-Chloro-7-deazapurine-2F-β-D-arabinofuranose

    CAS:
    6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.
    Formula:C11H11ClFN3O3
    Color and Shape:Solid
    Molecular weight:287.67

    Ref: TM-TNU0055

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
    500mg
    To inquire
  • E-64d [for Biochemical Research]

    CAS:
    Formula:C17H30N2O5
    Purity:>95.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:342.44

    Ref: 3B-E1337

    5mg
    114.00€
    25mg
    361.00€
  • MMP-8 Inhibitor I

    CAS:
    MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
    Formula:C17H18N2O5S
    Color and Shape:Solid
    Molecular weight:362.4

    Ref: TM-T69666

    1mg
    642.00€
  • PSI-6206 13C,d3

    CAS:

    PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.

    Formula:C10H13FN2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:264.23

    Ref: TM-T12571

    1mg
    329.00€
    5mg
    1,415.00€
  • Sitagliptin fenilalanil

    CAS:
    Sitagliptin fenilalanil is a dipeptidyl aminopeptidase (DPP-4) inhibitor.
    Formula:C25H24F6N6O2
    Color and Shape:Solid
    Molecular weight:554.49

    Ref: TM-T63915

    2mg
    60.00€
  • Ubenimex Hydrochloride [for Biochemical Research]

    CAS:
    Formula:C16H24N2O4·HCl
    Purity:>97.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:344.84

    Ref: 3B-B4000

    25mg
    135.00€
  • PKSI-527

    CAS:
    PKSI-527 inhibits plasma kallikrein (Ki=0.81μM), selective vs. glandular kallikrein/thrombin/urokinase/Xa, reduces bradykinin, affects clotting times.
    Formula:C25H32ClN3O4
    Color and Shape:Solid
    Molecular weight:473.99

    Ref: TM-T35579

    2mg
    81.00€
  • Glutaminase-IN-3

    CAS:
    Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.
    Formula:C19H19F3N6O2S
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:452.45

    Ref: TM-T37385

    5mg
    59.00€
    10mg
    84.00€
    25mg
    119.00€
    50mg
    170.00€
    100mg
    251.00€
    1mL*10mM (DMSO)
    73.00€
  • Ilomastat

    CAS:
    Formula:C20H28N4O4
    Purity:>95.0%(HPLC)(qNMR)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:388.47

    Ref: 3B-I1202

    10mg
    119.00€
  • Tomeglovir

    CAS:
    Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).
    Formula:C23H27N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:441.54

    Ref: TM-TQ0030

    2mg
    54.00€
  • Thrombin inhibitor 5

    CAS:
    Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.
    Formula:C11H9FN4O3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:264.21

    Ref: TM-T9845

    2mg
    35.00€
    5mg
    56.00€
    10mg
    86.00€
    25mg
    154.00€
    50mg
    224.00€
    100mg
    320.00€
    200mg
    434.00€
    1mL*10mM (DMSO)
    55.00€
  • Tilpisertib

    CAS:
    Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).
    Formula:C33H33ClN8O
    Color and Shape:Solid
    Molecular weight:593.13

    Ref: TM-T39466

    5mg
    873.00€
  • Dabigatran ethyl ester

    CAS:
    Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.
    Formula:C27H29N7O3
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:499.56

    Ref: TM-T15046

    2mg
    38.00€
    5mg
    51.00€
    10mg
    94.00€
    25mg
    155.00€
    50mg
    261.00€
    100mg
    410.00€
  • BAY-677

    CAS:
    BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.
    Formula:C20H15F3N4O2
    Color and Shape:Solid
    Molecular weight:400.35

    Ref: TM-T10473L

    2mg
    85.00€
  • PD-166793

    CAS:
    PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.
    Formula:C17H18BrNO4S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:412.3

    Ref: TM-T20563

    5mg
    42.00€
    10mg
    60.00€
    25mg
    112.00€
    50mg
    175.00€
    100mg
    261.00€
    200mg
    368.00€
    1mL*10mM (DMSO)
    46.00€
  • H-Arg-4MβNA

    CAS:
    H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.
    Formula:C17H23N5O2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:329.4

    Ref: TM-T19347

    5mg
    33.00€
  • (Arg)9

    CAS:
    (Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).
    Formula:C54H110N36O10
    Color and Shape:Solid
    Molecular weight:1423.69

    Ref: TM-T13976

    100mg
    To inquire
    500mg
    To inquire
  • DMP 777

    CAS:
    DMP 777 is an orally active inhibitor of human leukocyte elastase.
    Formula:C31H40N4O6
    Color and Shape:Solid
    Molecular weight:564.67

    Ref: TM-T15144

    2mg
    88.00€
    5mg
    152.00€
    1mL*10mM (DMSO)
    205.00€
  • ML-345

    CAS:
    ML-345, Selective IDE inhibitor (IC50=188 nM) targeting Cys819, for type 2 diabetes and Alzheimer's research.
    Formula:C21H22FN3O5S2
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:479.55

    Ref: TM-T35802

    1mg
    39.00€
    5mg
    84.00€
    10mg
    120.00€
    25mg
    197.00€
    50mg
    To inquire
    100mg
    434.00€
    1mL*10mM (DMSO)
    To inquire
  • Teneligliptin D8

    CAS:
    Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.
    Formula:C22H30N6OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:434.63

    Ref: TM-T13121

    1mg
    595.00€
    5mg
    1,431.00€
    10mg
    1,963.00€
    25mg
    2,907.00€
  • 5-Amino-8-hydroxyquinoline

    CAS:
    5-Amino-8-hydroxyquinoline(5A8HQ),Proteasome inhibitor. Potential anticancer agent.
    Formula:C9H8N2O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:160.17

    Ref: TM-T60234

    25mg
    34.00€
    50mg
    44.00€
    100mg
    56.00€
    500mg
    113.00€
    1mL*10mM (DMSO)
    44.00€
  • Trisodium Hydrogen Ethylenediaminetetraacetate Hydrate [for Biochemical Research]

    CAS:
    Formula:C10H13N2Na3O8·xH2O
    Purity:>98.0%(T)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:358.19 (as Anhydrous)

    Ref: 3B-T2599

    5g
    22.00€
    25g
    35.00€
  • Pepstatin A

    CAS:
    Formula:C34H63N5O9
    Purity:>90.0%(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:685.90

    Ref: 3B-P3041

    10mg
    102.00€
  • 4-Butylresorcinol

    CAS:
    4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
    Formula:C10H14O2
    Purity:99.48% - ≥95%
    Color and Shape:Light Beige Solid Powder
    Molecular weight:166.22

    Ref: TM-T7125

    200mg
    33.00€
    1mL*10mM (DMSO)
    33.00€
  • Anagliptin hydrochloride

    CAS:
    Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.
    Formula:C19H26ClN7O2
    Color and Shape:Solid
    Molecular weight:419.91

    Ref: TM-T62213

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • GW280264X

    CAS:
    GW280264X (Carbamic acid) is an inhibitor of ADAM17 .
    Formula:C28H41N5O6S
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:575.72

    Ref: TM-T8961

    1mg
    156.00€
    5mg
    319.00€
    10mg
    477.00€
    25mg
    773.00€
    50mg
    1,063.00€
    100mg
    1,431.00€
    1mL*10mM (DMSO)
    404.00€
  • UAMC00039 dihydrochloride

    CAS:
    UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.
    Formula:C16H26Cl3N3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:382.76

    Ref: TM-T4467

    1mg
    42.00€
    5mg
    94.00€
    10mg
    152.00€
    25mg
    295.00€
    50mg
    447.00€
    100mg
    623.00€
    1mL*10mM (DMSO)
    88.00€
  • PSI-6206

    CAS:
    PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.
    Formula:C10H13FN2O5
    Purity:98% - 99.79%
    Color and Shape:Solid
    Molecular weight:260.22

    Ref: TM-T2117

    25mg
    34.00€
    50mg
    39.00€
    100mg
    50.00€
    200mg
    66.00€
    1mL*10mM (DMSO)
    33.00€
  • Daclatasvir dihydrochloride

    CAS:
    Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.
    Formula:C40H52Cl2N8O6
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:811.8

    Ref: TM-T1786

    1g
    230.00€
    5mg
    39.00€
    10mg
    48.00€
    25mg
    57.00€
    50mg
    67.00€
    100mg
    77.00€
    500mg
    161.00€
    1mL*10mM (DMSO)
    49.00€
  • Ledipasvir hydrochloride

    CAS:
    Ledipasvir hydrochloride, a hepatitis C NS5A inhibitor, has EC50 of 34 pM (1a) and 4 pM (1b), also inhibits SARS-CoV 3CL pro (IC50 1.62 µM).
    Formula:C49H55ClF2N8O6
    Color and Shape:Solid
    Molecular weight:925.46

    Ref: TM-T75241

    25mg
    2,178.00€
    50mg
    2,862.00€
    100mg
    3,870.00€
  • T-26c

    CAS:
    T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).
    Formula:C24H21N3O6S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:479.51

    Ref: TM-T5361

    1mg
    48.00€
    2mg
    64.00€
    5mg
    96.00€
    10mg
    153.00€
    25mg
    250.00€
    50mg
    424.00€
    100mg
    613.00€
    1mL*10mM (DMSO)
    97.00€