CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 1093 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • HIV-1 TAT (48-60) Acetate


    Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.
    Formula:C72H135N35O18
    Purity:99.93%
    Color and Shape:Soild
    Molecular weight:1779.07

    Ref: TM-T75964L

    1mg
    74.00€
    5mg
    150.00€
    10mg
    214.00€
    25mg
    364.00€
    50mg
    536.00€
  • L-Methionine-DL-sulfoximine

    CAS:
    MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.
    Formula:C5H12N2O3S
    Purity:99.56% - ≥98%
    Color and Shape:White Crystalline Powder
    Molecular weight:180.23

    Ref: TM-T41299

    50mg
    42.00€
    100mg
    55.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
    To inquire
    50mg
    To inquire
  • Proteasome-IN-7


    Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.
    Formula:C48H56N6O10S
    Color and Shape:Solid
    Molecular weight:909.06

    Ref: TM-T205355

    10mg
    To inquire
    50mg
    To inquire
  • Chymotrypsinogen

    CAS:
    Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .
    Color and Shape:Solid

    Ref: TM-T76157

    5mg
    To inquire
    50mg
    To inquire
  • Suc-AAP-Abu-pNA

    CAS:
    Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,
    Formula:C25H34N6O9
    Color and Shape:Solid
    Molecular weight:562.57

    Ref: TM-T36351

    1mg
    139.00€
  • Fotagliptin

    CAS:
    Fotagliptin is a dipeptidyl peptidase IV inhibitor.
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37

    Ref: TM-T27353

    5mg
    1,491.00€
    50mg
    3,022.00€
    100mg
    4,085.00€
  • VD2173

    CAS:
    <p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
    To inquire
    50mg
    To inquire
  • VAMP


    <p>VAMP is a tetrapeptide that acts as a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor, exhibiting an IC50 of 1.00 μM and a Kd of 6.89 μM. It effectively targets the DPP-IV-GLP-1 axis and is utilized in the research of type 2 diabetes.</p>
    Formula:C18H32N4O5S
    Color and Shape:Solid
    Molecular weight:416.535

    Ref: TM-TP3084

    10mg
    To inquire
    50mg
    To inquire
  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
    To inquire
    50mg
    To inquire
  • Stevia Powder


    Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.
    Color and Shape:Odour Solid

    Ref: TM-TN8189

    10mg
    To inquire
    50mg
    To inquire
  • TMC647055 Choline salt


    TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91

    Ref: TM-T13170

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Cathepsin C-IN-6


    Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T79496

    5mg
    To inquire
    50mg
    To inquire
  • Sofosbuvir impurity J

    CAS:
    Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H30FN4O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.47

    Ref: TM-T12965

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid

    Ref: TM-T82510

    5mg
    To inquire
    50mg
    To inquire
  • DPP-4-IN-14


    <p>DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.</p>
    Formula:C33H27N7O3
    Color and Shape:Solid
    Molecular weight:569.613

    Ref: TM-T204855

    10mg
    To inquire
    50mg
    To inquire
  • Rivulariapeptolides 988


    Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).
    Formula:C50H68N8O13
    Color and Shape:Solid
    Molecular weight:989.12

    Ref: TM-T75651

    5mg
    To inquire
    50mg
    To inquire
  • PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08

    Ref: TM-T24674

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • PF 00356231

    CAS:
    <p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>
    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T60071

    1mg
    185.00€
    5mg
    415.00€
    10mg
    622.00€
    25mg
    1,119.00€
    50mg
    1,679.00€
    100mg
    2,520.00€
    200mg
    3,780.00€
  • Alisporivir

    CAS:
    Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64

    Ref: TM-T14180

    1mg
    187.00€
    5mg
    472.00€
    10mg
    687.00€
    25mg
    1,074.00€
    50mg
    1,444.00€