
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(110 products)
- DPP-4(20 products)
- Glutaminase(44 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(95 products)
- Serine Protease(56 products)
- p97(15 products)
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Found 1093 products of "Proteases/Proteasome"
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Roseltide rT1
CAS:Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.Formula:C110H177N31O31S6Color and Shape:SolidMolecular weight:2622.16Histargin
CAS:Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.Formula:C14H25N7O4Color and Shape:SolidMolecular weight:355.39Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormula:C47H64N14O10Color and Shape:SolidMolecular weight:985.1DPP8/9-IN-1
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.Color and Shape:Odour SolidCalpain Inhibitor-1
CAS:Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Formula:C19H17FN6O5SColor and Shape:SolidMolecular weight:460.44HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormula:C14H10N4O4SPurity:99.33%Color and Shape:SolidMolecular weight:330.32midesteine
CAS:Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.Formula:C12H13NO3S3Purity:99.87% - 99.98%Color and Shape:SolidMolecular weight:315.436,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFormula:C30H42N2O4SColor and Shape:SolidMolecular weight:526.73Berotralstat
CAS:Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.Formula:C30H26F4N6OColor and Shape:SolidMolecular weight:562.56EP 171
CAS:EP 171 is a potent agonist of TP-receptors.Formula:C23H29FO5Color and Shape:SolidMolecular weight:404.47ZG36
ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrialColor and Shape:Odour SolidRivulariapeptolides 1155
Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).Formula:C59H81N9O15Color and Shape:SolidMolecular weight:1156.33PR 39 (porcine) acetate
PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.Purity:98%Color and Shape:LiquidMolecular weight:N/AGrazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Formula:C38H49KN6O9SColor and Shape:SolidMolecular weight:805Neutrophil elastase inhibitor 4
Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.Formula:C20H21N3O5Color and Shape:SolidMolecular weight:383.4Leptosphaerodione
CAS:Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.Formula:C21H22O5Color and Shape:SolidMolecular weight:354.4Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Formula:C26H34N4O6Color and Shape:SolidMolecular weight:498.57Obtusifolin-2-O-glucoside
CAS:Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].Formula:C22H22O10Color and Shape:SolidMolecular weight:446.4Cyanopeptolin 954
CAS:Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.Formula:C46H63ClN8O12Purity:98%Color and Shape:SolidMolecular weight:955.5Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Color and Shape:Odour Solid

