CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 1093 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Roseltide rT1

    CAS:
    Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.
    Formula:C110H177N31O31S6
    Color and Shape:Solid
    Molecular weight:2622.16

    Ref: TM-TP3226

    10mg
    To inquire
    50mg
    To inquire
  • Histargin

    CAS:
    Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.
    Formula:C14H25N7O4
    Color and Shape:Solid
    Molecular weight:355.39

    Ref: TM-T25504

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

    CAS:
    Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect
    Formula:C47H64N14O10
    Color and Shape:Solid
    Molecular weight:985.1

    Ref: TM-T76347

    5mg
    To inquire
    50mg
    To inquire
  • DPP8/9-IN-1


    DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.
    Color and Shape:Odour Solid

    Ref: TM-T206718

    10mg
    To inquire
    50mg
    To inquire
  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,990.00€
  • HIV-1 inhibitor-6 

    CAS:
    HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32

    Ref: TM-T9854

    1mg
    75.00€
    5mg
    169.00€
    10mg
    284.00€
    25mg
    452.00€
    50mg
    645.00€
    100mg
    867.00€
    500mg
    To inquire
  • midesteine

    CAS:
    Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.
    Formula:C12H13NO3S3
    Purity:99.87% - 99.98%
    Color and Shape:Solid
    Molecular weight:315.43

    Ref: TM-T68099

    1mg
    50.00€
    5mg
    111.00€
    10mg
    165.00€
    25mg
    266.00€
    50mg
    379.00€
    100mg
    540.00€
    200mg
    757.00€
  • 6,6′-Dihydroxythiobinupharidine

    CAS:
    6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold
    Formula:C30H42N2O4S
    Color and Shape:Solid
    Molecular weight:526.73

    Ref: TM-T79978

    5mg
    To inquire
    50mg
    To inquire
  • Berotralstat

    CAS:
    Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.
    Formula:C30H26F4N6O
    Color and Shape:Solid
    Molecular weight:562.56

    Ref: TM-T35869

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • EP 171

    CAS:
    EP 171 is a potent agonist of TP-receptors.
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47

    Ref: TM-T27273

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • ZG36


    ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial
    Color and Shape:Odour Solid

    Ref: TM-T80737

    5mg
    To inquire
    50mg
    To inquire
  • Rivulariapeptolides 1155


    Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).
    Formula:C59H81N9O15
    Color and Shape:Solid
    Molecular weight:1156.33

    Ref: TM-T75648

    5mg
    To inquire
    50mg
    To inquire
  • PR 39 (porcine) acetate


    PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.
    Purity:98%
    Color and Shape:Liquid
    Molecular weight:N/A

    Ref: TM-TP1961L

    1mg
    187.00€
    5mg
    472.00€
    10mg
    708.00€
    25mg
    1,274.00€
    50mg
    1,898.00€
  • Grazoprevir potassium salt

    CAS:
    <p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805

    Ref: TM-T19948

    50mg
    To inquire
    100mg
    To inquire
  • Neutrophil elastase inhibitor 4


    Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T79397

    5mg
    To inquire
    50mg
    To inquire
  • Leptosphaerodione

    CAS:
    Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.
    Formula:C21H22O5
    Color and Shape:Solid
    Molecular weight:354.4

    Ref: TM-T75488

    5mg
    To inquire
    50mg
    To inquire
  • Ac-PAL-AMC

    CAS:
    Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57

    Ref: TM-T37421

    1mg
    255.00€
    5mg
    998.00€
    10mg
    1,758.00€
  • Obtusifolin-2-O-glucoside

    CAS:
    Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].
    Formula:C22H22O10
    Color and Shape:Solid
    Molecular weight:446.4

    Ref: TM-T75572

    5mg
    To inquire
    50mg
    To inquire
  • Cyanopeptolin 954

    CAS:
    Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.
    Formula:C46H63ClN8O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:955.5

    Ref: TM-T25280

    5mg
    To inquire
  • Stevia Powder


    Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.
    Color and Shape:Odour Solid

    Ref: TM-TN8189

    10mg
    To inquire
    50mg
    To inquire