
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(51 products)
- Cysteine Protease(139 products)
- DPP-4(91 products)
- Glutaminase(48 products)
- HIV Protease(501 products)
- PAI-1(31 products)
- Protease Inhibitors(49 products)
- Protease-activated Receptor(57 products)
- Proteasome(71 products)
- Serine Protease(81 products)
- p97(15 products)
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Found 928 products for "Proteases/Proteasome".
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S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Formula:C33H40N8O6Color and Shape:SolidMolecular weight:644.72NVP-DPP728 dihydrochloride
CAS:NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.Formula:C15H20Cl2N6OColor and Shape:SolidMolecular weight:371.27HCV-IN-30
CAS:HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Formula:C36H44N6O4Purity:99.6%Color and Shape:White SolidMolecular weight:624.77Isoleucylvaline
CAS:Isoleucylvaline is a dipeptide.Formula:C11H22N2O3Color and Shape:SolidMolecular weight:230.30AGG-523
CAS:AGG-523, an aggrecanase inhibitor, may slow cartilage wear after joint injury by reducing ARG-aggrecan in rats.Formula:C28H29FN2O4Color and Shape:SolidMolecular weight:476.54Cathepsin Inhibitor 1
CAS:Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.Formula:C20H24ClN5O2Purity:99.78%Color and Shape:SolidMolecular weight:401.89Ref: TM-T6015
1mg46.00€5mg90.00€1mL*10mM (DMSO)100.00€10mg144.00€25mg236.00€50mg371.00€100mg522.00€200mg743.00€Carboxypeptidase G2 (CPG2) Inhibitor
CAS:Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.Formula:C13H15NO6SPurity:99.96%Color and Shape:SolidMolecular weight:313.33Chymase-IN-1
CAS:Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).Formula:C20H15ClNO4PSPurity:99.17%Color and Shape:SolidMolecular weight:431.83Ref: TM-T10811
1mg146.00€5mg349.00€1mL*10mM (DMSO)384.00€10mg497.00€25mg745.00€50mg999.00€100mg1,341.00€500mg2,655.00€ER 27319 maleate
CAS:Selective inhibitor of Syk kinaseFormula:C22H24N2O5Purity:98.45%Color and Shape:Yellow SolidMolecular weight:396.44Diprotin B
CAS:Diprotin B is a dipeptidyl peptidase IV inhibitor.Formula:C16H29N3O4Purity:98%Color and Shape:SolidMolecular weight:327.42RLVT-14-02
RLVT-14-02 is a human monoclonal antibody (mAb) targeting MMP14. It is applicable in the study of neuropathic pain.ABX-MA1
CAS:ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.Eflumenibep alfa
CAS:Eflumenibep alfa is a kallikrein 5 (Kallikrein5) inhibitor with anti-inflammatory properties. This fusion protein consists of human SPINK2 and the human IgG1 Fc fragment connected at the C-terminus.REGN7999
REGN7999 is a monoclonal antibody that inhibits TMPRSS6. By suppressing TMPRSS6 activity, REGN7999 prevents HJV cleavage, enhancing BMP6-HJV signaling and increasing serum hepcidin levels. This inhibition aids in alleviating iron overload and impaired erythropoiesis in β-thalassemia mouse models. REGN7999 is applicable for research in β-thalassemia.Invobenitug
CAS:Invobenitug is a humanized IgG1κ monoclonal antibody that targets DPP3, with the corresponding isotype control being HumanIgG1kappa, Isotype Control.CM-338
CM-338 is a human monoclonal antibody (mAb) targeting MASP2. It is useful for research related to IgA nephropathy.Tyrosinase-IN-4
CAS:Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.Formula:C15H9ClO3Color and Shape:SolidMolecular weight:272.68YD-3
CAS:YD-3 is a PAR4 antagonist that significantly inhibits thrombin-induced platelet aggregation in rabbits (IC(50)=28.3 microM). In addition, YD-3 suppresses thrombin-induced proliferation of vascular smooth muscle cells (VSMCs) and reduces neointimal thickening after balloon injury. Through Ras- and ERK1/2-mediated signaling pathways, YD-3 impedes thrombin-driven VSMC proliferation. When analyzed with Western blot, YD-3 primarily inhibits thrombin-induced expression of vascular endothelial growth factor receptor 2 (Flk-1) without affecting extracellular signal-regulated kinase 1/2 phosphorylation. YD-3 could potentially have value in elucidating the pathophysiology of thrombin-induced angiogenesis.Formula:C23H20N2O2Color and Shape:SolidMolecular weight:356.42MyoMed 205
CAS:MyoMed-205 is an inhibitor of MuRF1 (muscle ring finger protein 1) activity. It effectively prevents early diaphragm contractile dysfunction and atrophy following 12 hours of unilateral phrenic nerve denervation. By inhibiting MuRF1, MyoMed-205 reduces muscle protein ubiquitination and subsequent proteasome degradation. It also increases the protein levels of phosphorylated Akt (ser473), an essential signaling molecule for muscle growth and maintenance. MyoMed-205 is applicable in the research and treatment of diaphragm dysfunction and atrophy (DIDD) due to early disuse, particularly in clinical situations such as diaphragm paralysis or mechanical ventilation.Formula:C26H25N3O5SColor and Shape:SolidMolecular weight:491.56Tanomastat
CAS:Tanomastat is an oral, non-peptidic MMP inhibitor with Ki values of 11, 143, 301, and 1470 nM for MMP-2, -3, -9, and -13, respectively.Formula:C23H19ClO3SPurity:98%Color and Shape:SolidMolecular weight:410.91

