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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 928 products for "Proteases/Proteasome".

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  • S 2160

    CAS:
    S 2160 is a synthetic chromogenic substrate for thrombin.
    Formula:C33H40N8O6
    Color and Shape:Solid
    Molecular weight:644.72

    Ref: TM-T34461

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • NVP-DPP728 dihydrochloride

    CAS:
    NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27

    Ref: TM-T39481

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • HCV-IN-30

    CAS:
    HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).
    Formula:C36H44N6O4
    Purity:99.6%
    Color and Shape:White Solid
    Molecular weight:624.77

    Ref: TM-T11541

    1mL*10mM (DMSO)
    33.00€
    50mg
    39.00€
    100mg
    58.00€
    500mg
    138.00€
  • Isoleucylvaline

    CAS:
    Isoleucylvaline is a dipeptide.
    Formula:C11H22N2O3
    Color and Shape:Solid
    Molecular weight:230.30

    Ref: TM-T32214

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AGG-523

    CAS:
    AGG-523, an aggrecanase inhibitor, may slow cartilage wear after joint injury by reducing ARG-aggrecan in rats.
    Formula:C28H29FN2O4
    Color and Shape:Solid
    Molecular weight:476.54

    Ref: TM-T68344

    25mg
    1,468.00€
    50mg
    1,972.00€
    100mg
    2,440.00€
  • Cathepsin Inhibitor 1

    CAS:
    Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
    Formula:C20H24ClN5O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:401.89

    Ref: TM-T6015

    1mg
    46.00€
    5mg
    90.00€
    1mL*10mM (DMSO)
    100.00€
    10mg
    144.00€
    25mg
    236.00€
    50mg
    371.00€
    100mg
    522.00€
    200mg
    743.00€
  • Carboxypeptidase G2 (CPG2) Inhibitor

    CAS:
    Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.
    Formula:C13H15NO6S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:313.33

    Ref: TM-T10678

    1mg
    34.00€
    5mg
    71.00€
    10mg
    100.00€
    25mg
    172.00€
    50mg
    249.00€
    100mg
    346.00€
    200mg
    494.00€
  • Chymase-IN-1

    CAS:
    Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
    Formula:C20H15ClNO4PS
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:431.83

    Ref: TM-T10811

    1mg
    146.00€
    5mg
    349.00€
    1mL*10mM (DMSO)
    384.00€
    10mg
    497.00€
    25mg
    745.00€
    50mg
    999.00€
    100mg
    1,341.00€
    500mg
    2,655.00€
  • ER 27319 maleate

    CAS:
    Selective inhibitor of Syk kinase
    Formula:C22H24N2O5
    Purity:98.45%
    Color and Shape:Yellow Solid
    Molecular weight:396.44

    Ref: TM-T22766

    1mg
    56.00€
    5mg
    118.00€
    10mg
    178.00€
    25mg
    371.00€
    50mg
    595.00€
    100mg
    954.00€
  • Diprotin B

    CAS:
    Diprotin B is a dipeptidyl peptidase IV inhibitor.
    Formula:C16H29N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:327.42

    Ref: TM-T25341

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • RLVT-14-02


    RLVT-14-02 is a human monoclonal antibody (mAb) targeting MMP14. It is applicable in the study of neuropathic pain.

    Ref: TM-T9901A-1647

    1mg
    To inquire
    5mg
    To inquire
  • ABX-MA1

    CAS:
    ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.

    Ref: TM-T9901A-1757

    1mg
    To inquire
    5mg
    To inquire
  • Eflumenibep alfa

    CAS:
    Eflumenibep alfa is a kallikrein 5 (Kallikrein5) inhibitor with anti-inflammatory properties. This fusion protein consists of human SPINK2 and the human IgG1 Fc fragment connected at the C-terminus.

    Ref: TM-T9901A-1855

    2mg
    To inquire
    5mg
    To inquire
    10mg
    To inquire
    1mg
    286.00€
  • REGN7999


    REGN7999 is a monoclonal antibody that inhibits TMPRSS6. By suppressing TMPRSS6 activity, REGN7999 prevents HJV cleavage, enhancing BMP6-HJV signaling and increasing serum hepcidin levels. This inhibition aids in alleviating iron overload and impaired erythropoiesis in β-thalassemia mouse models. REGN7999 is applicable for research in β-thalassemia.

    Ref: TM-T9901A-1925

    1mg
    To inquire
    5mg
    To inquire
  • Invobenitug

    CAS:
    Invobenitug is a humanized IgG1κ monoclonal antibody that targets DPP3, with the corresponding isotype control being HumanIgG1kappa, Isotype Control.

    Ref: TM-T9901A-1840

    2mg
    To inquire
    5mg
    To inquire
    10mg
    To inquire
    1mg
    200.00€
  • CM-338


    CM-338 is a human monoclonal antibody (mAb) targeting MASP2. It is useful for research related to IgA nephropathy.

    Ref: TM-T9901A-1698

    2mg
    To inquire
    5mg
    To inquire
    10mg
    To inquire
    1mg
    250.00€
  • Tyrosinase-IN-4

    CAS:
    Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.
    Formula:C15H9ClO3
    Color and Shape:Solid
    Molecular weight:272.68

    Ref: TM-T60484

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • YD-3

    CAS:
    YD-3 is a PAR4 antagonist that significantly inhibits thrombin-induced platelet aggregation in rabbits (IC(50)=28.3 microM). In addition, YD-3 suppresses thrombin-induced proliferation of vascular smooth muscle cells (VSMCs) and reduces neointimal thickening after balloon injury. Through Ras- and ERK1/2-mediated signaling pathways, YD-3 impedes thrombin-driven VSMC proliferation. When analyzed with Western blot, YD-3 primarily inhibits thrombin-induced expression of vascular endothelial growth factor receptor 2 (Flk-1) without affecting extracellular signal-regulated kinase 1/2 phosphorylation. YD-3 could potentially have value in elucidating the pathophysiology of thrombin-induced angiogenesis.
    Formula:C23H20N2O2
    Color and Shape:Solid
    Molecular weight:356.42

    Ref: TM-T202985

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • MyoMed 205

    CAS:
    MyoMed-205 is an inhibitor of MuRF1 (muscle ring finger protein 1) activity. It effectively prevents early diaphragm contractile dysfunction and atrophy following 12 hours of unilateral phrenic nerve denervation. By inhibiting MuRF1, MyoMed-205 reduces muscle protein ubiquitination and subsequent proteasome degradation. It also increases the protein levels of phosphorylated Akt (ser473), an essential signaling molecule for muscle growth and maintenance. MyoMed-205 is applicable in the research and treatment of diaphragm dysfunction and atrophy (DIDD) due to early disuse, particularly in clinical situations such as diaphragm paralysis or mechanical ventilation.
    Formula:C26H25N3O5S
    Color and Shape:Solid
    Molecular weight:491.56

    Ref: TM-T88288

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Tanomastat

    CAS:
    Tanomastat is an oral, non-peptidic MMP inhibitor with Ki values of 11, 143, 301, and 1470 nM for MMP-2, -3, -9, and -13, respectively.
    Formula:C23H19ClO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.91

    Ref: TM-T16986

    1mg
    150.00€