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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 921 products for "Proteases/Proteasome".

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  • PSI

    CAS:
    PSI is a proteasome inhibitor.
    Formula:C32H50N4O8
    Purity:97% - 98.33%
    Color and Shape:Solid
    Molecular weight:618.76

    Ref: TM-T21510

    1mg
    93.00€
    5mg
    236.00€
    10mg
    401.00€
    25mg
    650.00€
    50mg
    897.00€
    100mg
    1,198.00€
  • Danoprevir

    CAS:
    Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).
    Formula:C35H46FN5O9S
    Purity:98% - 99.80%
    Color and Shape:Yellow Solid
    Molecular weight:731.83

    Ref: TM-T6025

    1mg
    59.00€
    5mg
    130.00€
    1mL*10mM (DMSO)
    202.00€
    10mg
    222.00€
    25mg
    379.00€
    50mg
    563.00€
    100mg
    800.00€
  • Triton X-45(n=4)

    CAS:
    Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.
    Formula:C22H38O5
    Color and Shape:Solid
    Molecular weight:382.53

    Ref: TM-T39852

    50mg
    To inquire
    100mg
    To inquire
    25mg
    203.00€
  • KZR-504

    CAS:
    KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
    Formula:C21H23N3O6
    Color and Shape:Solid
    Molecular weight:413.42

    Ref: TM-T15678

    1mg
    1,066.00€
    5mg
    2,347.00€
  • (-)-Gallocatechin Gallate

    CAS:
    Formula:C22H18O11
    Purity:>95.0%(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:458.38

    Ref: 3B-G0628

    25mg
    226.00€
  • Nelfinavir Mesylate

    CAS:
    Formula:C32H45N3O4S·CH4O3S
    Purity:>97.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:663.89

    Ref: 3B-N0986

    25mg
    182.00€
    100mg
    493.00€
  • ALLM

    CAS:
    ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].
    Formula:C19H35N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:401.56

    Ref: TM-T14187

    1mg
    78.00€
    5mg
    168.00€
    10mg
    286.00€
    25mg
    475.00€
  • HCV-IN-30

    CAS:
    HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).
    Formula:C36H44N6O4
    Purity:99.6%
    Color and Shape:White Solid
    Molecular weight:624.77

    Ref: TM-T11541

    1mL*10mM (DMSO)
    33.00€
    50mg
    39.00€
    100mg
    58.00€
    500mg
    138.00€
  • AGG-523

    CAS:
    AGG-523, an aggrecanase inhibitor, may slow cartilage wear after joint injury by reducing ARG-aggrecan in rats.
    Formula:C28H29FN2O4
    Color and Shape:Solid
    Molecular weight:476.54

    Ref: TM-T68344

    25mg
    1,468.00€
    50mg
    1,972.00€
    100mg
    2,440.00€
  • NVP-DPP728 dihydrochloride

    CAS:
    NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27

    Ref: TM-T39481

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • S 2160

    CAS:
    S 2160 is a synthetic chromogenic substrate for thrombin.
    Formula:C33H40N8O6
    Color and Shape:Solid
    Molecular weight:644.72

    Ref: TM-T34461

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Carboxypeptidase G2 (CPG2) Inhibitor

    CAS:
    Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.
    Formula:C13H15NO6S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:313.33

    Ref: TM-T10678

    1mg
    34.00€
    5mg
    71.00€
    10mg
    100.00€
    25mg
    172.00€
    50mg
    249.00€
    100mg
    346.00€
    200mg
    494.00€
  • Cathepsin Inhibitor 1

    CAS:
    Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
    Formula:C20H24ClN5O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:401.89

    Ref: TM-T6015

    1mg
    46.00€
    5mg
    90.00€
    1mL*10mM (DMSO)
    100.00€
    10mg
    144.00€
    25mg
    236.00€
    50mg
    371.00€
    100mg
    522.00€
    200mg
    743.00€
  • Flovagatran

    CAS:
    Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.
    Formula:C27H36BN3O7
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:525.4

    Ref: TM-T31806

    1mg
    685.00€
    5mg
    1,431.00€
    10mg
    1,783.00€
    50mg
    2,322.00€
  • ER 27319 maleate

    CAS:
    Selective inhibitor of Syk kinase
    Formula:C22H24N2O5
    Purity:98.45%
    Color and Shape:Yellow Solid
    Molecular weight:396.44

    Ref: TM-T22766

    1mg
    56.00€
    5mg
    118.00€
    10mg
    178.00€
    25mg
    371.00€
    50mg
    595.00€
    100mg
    954.00€
  • Diprotin B

    CAS:
    Diprotin B is a dipeptidyl peptidase IV inhibitor.
    Formula:C16H29N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:327.42

    Ref: TM-T25341

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Tyrosinase-IN-4

    CAS:
    Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.
    Formula:C15H9ClO3
    Color and Shape:Solid
    Molecular weight:272.68

    Ref: TM-T60484

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • YD-3

    CAS:
    YD-3 is a PAR4 antagonist that significantly inhibits thrombin-induced platelet aggregation in rabbits (IC(50)=28.3 microM). In addition, YD-3 suppresses thrombin-induced proliferation of vascular smooth muscle cells (VSMCs) and reduces neointimal thickening after balloon injury. Through Ras- and ERK1/2-mediated signaling pathways, YD-3 impedes thrombin-driven VSMC proliferation. When analyzed with Western blot, YD-3 primarily inhibits thrombin-induced expression of vascular endothelial growth factor receptor 2 (Flk-1) without affecting extracellular signal-regulated kinase 1/2 phosphorylation. YD-3 could potentially have value in elucidating the pathophysiology of thrombin-induced angiogenesis.
    Formula:C23H20N2O2
    Color and Shape:Solid
    Molecular weight:356.42

    Ref: TM-T202985

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • MyoMed 205

    CAS:
    MyoMed-205 is an inhibitor of MuRF1 (muscle ring finger protein 1) activity. It effectively prevents early diaphragm contractile dysfunction and atrophy following 12 hours of unilateral phrenic nerve denervation. By inhibiting MuRF1, MyoMed-205 reduces muscle protein ubiquitination and subsequent proteasome degradation. It also increases the protein levels of phosphorylated Akt (ser473), an essential signaling molecule for muscle growth and maintenance. MyoMed-205 is applicable in the research and treatment of diaphragm dysfunction and atrophy (DIDD) due to early disuse, particularly in clinical situations such as diaphragm paralysis or mechanical ventilation.
    Formula:C26H25N3O5S
    Color and Shape:Solid
    Molecular weight:491.56

    Ref: TM-T88288

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Tanomastat

    CAS:
    Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.
    Formula:C23H19ClO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.91

    Ref: TM-T16986

    500µg
    92.00€
    1mg
    159.00€
    5mg
    487.00€
    10mg
    892.00€