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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1094 products of "Proteases/Proteasome"

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  • GSK2818713

    CAS:
    GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
    Formula:C46H56N8O8
    Color and Shape:Solid
    Molecular weight:849.002
  • MK-6169

    CAS:
    MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.
    Formula:C54H62FN9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1016.2
  • APC-6860

    CAS:
    APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13
  • Alisporivir

    CAS:
    Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64
  • Sadopeptins B


    Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18
  • PF 00356231

    CAS:
    <p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>
    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5
  • Ac-PAL-AMC

    CAS:
    Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57
  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07
  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid
  • Sofosbuvir impurity J

    CAS:
    Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H30FN4O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.47
  • C-telopeptide

    CAS:
    C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.
    Formula:C34H56N14O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:868.9
  • Ellipyrone B


    Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57
  • HIV-1 inhibitor-6 

    CAS:
    HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32
  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47
  • Neutrophil elastase inhibitor 4


    Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4
  • Grazoprevir potassium salt

    CAS:
    <p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805
  • PR 39 (porcine) acetate


    PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.
    Purity:98%
    Color and Shape:Liquid
    Molecular weight:N/A
  • Acetyl-Calpastatin(184-210)(human)

    CAS:
    Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.
    Formula:C142H230N36O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3177.65
  • 5-epi-Arvestonate A

    CAS:
    <p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>
    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37