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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1094 products of "Proteases/Proteasome"

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  • (Rac)-Telmesteine

    CAS:
    <p>(Rac)-Telmesteine (3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester) is an inhibitor of protease and is thus a suitable enzyme stabilizer.</p>
    Formula:C7H11NO4S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:205.23
  • CL-82198

    CAS:
    CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA).
    Formula:C17H22N2O3
    Purity:95.91%
    Color and Shape:Solid
    Molecular weight:302.37
  • RA190

    CAS:
    RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
    Formula:C28H23Cl5N2O2
    Purity:97.7%
    Color and Shape:Solid
    Molecular weight:596.76
  • Incyclinide

    CAS:
    Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor.
    Formula:C19H17NO7
    Purity:97.99%
    Color and Shape:Solid
    Molecular weight:371.34
  • 3-Aminopropionitrile fumarate (2:1)

    CAS:
    3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) is an organic compound and antirheumatic agent used in veterinary medicine.
    Formula:C4H4O4·2C3H6N2
    Purity:99.76% - 99.79%
    Color and Shape:White Crystalline Powder
    Molecular weight:256.26
  • NBD-556

    CAS:
    NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.
    Formula:C17H24ClN3O2
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:337.84
  • Ruzasvir

    CAS:
    Ruzasvir (MK-8408) is a novel and potent pan-genotypic inhibitor of hepatitis C virus NS5A with antiviral activity.
    Formula:C49H55FN10O7S
    Purity:96.87% - 99.93%
    Color and Shape:Solid
    Molecular weight:947.09
  • Trelagliptin

    CAS:
    Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
    Formula:C18H20FN5O2
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:357.38
  • Dabigatran etexilate

    CAS:
    Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.
    Formula:C34H41N7O5
    Purity:98.19% - 99.98%
    Color and Shape:White Powder
    Molecular weight:627.73
  • Levovirin

    CAS:
    <p>Levovirin (L-Ribavirin) is a guanosine nucleoside analog that has immunomodulatory activity and is used in the study of hepatitis C virus infection.</p>
    Formula:C8H12N4O5
    Purity:99.81% - >99.99%
    Color and Shape:Solid
    Molecular weight:244.20
  • ADAM8-IN-1

    CAS:
    <p>ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.</p>
    Formula:C44H44Br4N6O12S2
    Color and Shape:Solid
    Molecular weight:1232.6
  • HCV-IN-4

    CAS:
    HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.
    Formula:C52H58FN9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:956.07
  • APC-6860

    CAS:
    APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13
  • BMS-767778

    CAS:
    BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29
  • BPHA

    CAS:
    BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46
  • MMP-3 Inhibitor

    CAS:
    MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.
    Formula:C27H46N10O9S
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:686.78
  • PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08
  • Neutrophil elastase inhibitor 4


    Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4
  • 6-Acetylnimbandiol

    CAS:
    6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.
    Formula:C28H34O8
    Color and Shape:Solid
    Molecular weight:498.56
  • Tyrosinase-IN-38


    Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.
    Color and Shape:Odour Solid