CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 928 products for "Proteases/Proteasome".

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Saxagliptin hydrate

    CAS:
    Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).
    Formula:C18H25N3O2·H2O
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:333.43

    Ref: TM-T0178

    1mL*10mM (DMSO)
    33.00€
    10mg
    38.00€
    25mg
    58.00€
    50mg
    89.00€
    100mg
    119.00€
    500mg
    289.00€
  • Barbituric acid

    CAS:
    Barbituric acid is a pyrimidine derivative and the basic skeleton of barbiturate drugs, barbiturate drugs and other heterocyclic compounds.
    Formula:C4H4N2O3
    Purity:99.83%
    Molecular weight:128.09

    Ref: TM-T205940

    50mg
    58.00€
    100mg
    87.00€
  • LXE408 fumarate


    LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:559.51

    Ref: TM-T39214L

    1mg
    299.00€
    2mg
    447.00€
    5mg
    563.00€
    1mL*10mM (DMSO)
    830.00€
    10mg
    897.00€
    25mg
    1,324.00€
    50mg
    1,791.00€
    100mg
    2,412.00€
  • CDD-3290


    CDD-3290 serves as a functional therapeutic tool specifically designed to enable the precise detection and inhibition of the proteolytic activity of PSA which plays a pivotal role in the progression of prostate cancer during strictly monitored laboratory observation periods and molecular investigations to evaluate the pharmacological potential of targeted kallikrein inhibition in specialized preclinical research environments.
    Formula:C17H14N6O2
    Purity:99.06% - 99.13%
    Color and Shape:White Solid
    Molecular weight:334.33

    Ref: TM-T89314

    1mg
    172.00€
  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
    To inquire
    50mg
    To inquire
  • APC-6860

    CAS:
    APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13

    Ref: TM-T39029

    5mg
    873.00€
  • D-DOPA

    CAS:
    D-DOPA, an L-DOPA enantiomer, alters rat dopamine neurons and can modulate Parkinson's symptoms.
    Formula:C9H11NO4
    Color and Shape:Solid
    Molecular weight:197.19

    Ref: TM-T37605

    50mg
    178.00€
    100mg
    349.00€
    250mg
    717.00€
    500mg
    1,161.00€
  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    100.00€
    10mg
    148.00€
    50mg
    545.00€
  • Acetyl-Calpastatin(184-210)(human)

    CAS:
    Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.
    Formula:C142H230N36O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3177.65

    Ref: TM-TP2056

    1mg
    1,378.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
    To inquire
    50mg
    To inquire
  • PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08

    Ref: TM-T24674

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • BPHA

    CAS:
    BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T36712

    1mg
    167.00€
    5mg
    442.00€
    1mL*10mM (DMSO)
    442.00€
    10mg
    620.00€
    25mg
    954.00€
    50mg
    1,305.00€
    100mg
    1,738.00€
    200mg
    2,322.00€
  • Cathepsin D/E Substrate, Fluorogenic


    CathepsinD/E Substrate, Fluorogenic, is an 11-amino acid peptide specifically designed as a substrate for cathepsins D and E, demonstrating selectivity by not acting as a substrate for cathepsins B, H, or L.
    Formula:C83H119N21O18
    Color and Shape:Solid
    Molecular weight:1697.9042

    Ref: TM-TP3302

    10mg
    To inquire
    50mg
    To inquire
  • Grazoprevir potassium salt

    CAS:
    Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805

    Ref: TM-T19948

    50mg
    To inquire
    100mg
    To inquire
  • N-CBZ-Phe-Arg-AMC TFA


    N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.
    Formula:C35H37F3N6O8
    Purity:99.88%
    Color and Shape:White Solid
    Molecular weight:726.7

    Ref: TM-T76010

    1mg
    47.00€
    5mg
    92.00€
    10mg
    147.00€
    25mg
    289.00€
    50mg
    467.00€
  • cis-Lomibuvir

    CAS:
    cis-Lomibuvir is an NS5B polymerase inhibitor (Kd = 17 nM, EC₅₀ = 5.2 nM).
    Formula:C25H35NO4S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:445.61

    Ref: TM-T73814

    1mg
    To inquire
    5mg
    To inquire
    50mg
    To inquire
    10mg
    177.00€
    25mg
    335.00€
    100mg
    785.00€
  • 6,6′-Dihydroxythiobinupharidine

    CAS:
    6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold
    Formula:C30H42N2O4S
    Color and Shape:Solid
    Molecular weight:526.73

    Ref: TM-T79978

    5mg
    To inquire
    50mg
    To inquire
  • Suc-Leu-Leu-Val-Tyr-AMC

    CAS:
    Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic tetrapeptide substrate for 20S proteasome and chymotrypsin-like proteases, used in drug screening.
    Formula:C40H53N5O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:763.88

    Ref: TM-TP1308

    1mg
    51.00€
  • HCV-IN-4

    CAS:
    HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.
    Formula:C52H58FN9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:956.07

    Ref: TM-TP1468

    100mg
    To inquire
    500mg
    To inquire
  • Adamtsostatin 4

    CAS:
    Adamtsostatin 4, an anti-angiogenic peptide, is utilized in research related to angiogenesis inhibition [1].
    Formula:C80H121N27O27S2
    Molecular weight:1957.11

    Ref: TM-T83170

    5mg
    To inquire
    50mg
    To inquire