
Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase(59 products)
- Hedgehog/Smoothened(45 products)
- Hippo pathway(6 products)
- JAK(246 products)
- Porcupine(9 products)
- ROCK(69 products)
- STAT(98 products)
- Stem Cells(483 products)
- TGF-beta/Smad(58 products)
- Wnt/beta-catenin(66 products)
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Found 693 products of "Stem Cell and Derivatives"
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Upadacitinib tartrate
CAS:<p>Upadacitinib: potent, selective JAK1 inhibitor, 74x preferential to JAK2, effective in rat arthritis.</p>Formula:C21H33F3N6O11Purity:98%Color and Shape:SolidMolecular weight:602.521TCJL37
CAS:<p>TCJL37: potent, selective TYK2 inhibitor (K i 1.6 nM), oral, for IBD research.</p>Formula:C17H11ClF2N4O2Color and Shape:SolidMolecular weight:376.74Tyk2-IN-9
CAS:<p>Tyk2-IN-9: selective Tyk-2 inhibitor, IC50 of 0.076 nM (TYK2-JH2), 1.8 nM (JAK1-JH2), for inflammation/autoimmune research.</p>Formula:C20H17N9Purity:98%Color and Shape:SolidMolecular weight:383.41JAK-IN-17
<p>"JAK-IN-17: Potent JAK inhibitor for studying ocular, skin, and respiratory diseases."</p>Formula:C33H38F2N6O8Color and Shape:SolidMolecular weight:684.69BT-GSI
<p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.</p>Formula:C26H46BrN5O10P2Color and Shape:SolidMolecular weight:730.52JAK-IN-1
CAS:<p>JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.</p>Formula:C20H24N6O2Purity:98%Color and Shape:SolidMolecular weight:380.44Tubulin/JAK2-IN-1
CAS:<p>Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significant</p>Formula:C22H20N6O3Color and Shape:SolidMolecular weight:416.43Yhhu-3792 hydrochloride
CAS:<p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>Formula:C24H25ClN4O2Color and Shape:SolidMolecular weight:436.93STAT3-IN-B9
CAS:<p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>Formula:C20H13NO5SPurity:98.19%Color and Shape:SolidMolecular weight:379.39A 1070722
CAS:A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.Formula:C17H13F3N4O2Purity:99.9%Color and Shape:SolidMolecular weight:362.31JW 67
CAS:<p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>Formula:C21H18N2O6Purity:99.02%Color and Shape:SolidMolecular weight:394.38Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Formula:C42H70O12Purity:98.46% - 99.13%Color and Shape:SolidMolecular weight:767TP0427736
CAS:TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.Formula:C14H10N4S2Purity:97.26%Color and Shape:SolidMolecular weight:298.39ML115
CAS:<p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>Formula:C15H15ClN2O4Purity:99.97%Color and Shape:SolidMolecular weight:322.74MRK-560
CAS:MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.Formula:C19H17ClF5NO4S2Purity:98.87%Color and Shape:SolidMolecular weight:517.92ROCK-IN-1
CAS:<p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>Formula:C20H18FN3OPurity:>99.99%Color and Shape:SolidMolecular weight:335.37GNE-7883
CAS:<p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>Formula:C28H29FN6O2Purity:97.61%Color and Shape:SolidMolecular weight:500.57Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Formula:C30H26O10Purity:96.66%Color and Shape:SolidMolecular weight:546.52H-1152 dihydrochloride
CAS:<p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>Formula:C16H23Cl2N3O2SPurity:99.85%Color and Shape:SolidMolecular weight:392.34STAT6-IN-2
CAS:<p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>Formula:C28H31N5O2Purity:99.67%Color and Shape:SolidMolecular weight:469.58
