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Stem Cell and Derivatives

Stem Cell and Derivatives

Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.

Subcategories of "Stem Cell and Derivatives"

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Found 693 products of "Stem Cell and Derivatives"

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  • Upadacitinib tartrate

    CAS:
    <p>Upadacitinib: potent, selective JAK1 inhibitor, 74x preferential to JAK2, effective in rat arthritis.</p>
    Formula:C21H33F3N6O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:602.521
  • TCJL37

    CAS:
    <p>TCJL37: potent, selective TYK2 inhibitor (K i 1.6 nM), oral, for IBD research.</p>
    Formula:C17H11ClF2N4O2
    Color and Shape:Solid
    Molecular weight:376.74
  • Tyk2-IN-9

    CAS:
    <p>Tyk2-IN-9: selective Tyk-2 inhibitor, IC50 of 0.076 nM (TYK2-JH2), 1.8 nM (JAK1-JH2), for inflammation/autoimmune research.</p>
    Formula:C20H17N9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:383.41
  • JAK-IN-17


    <p>"JAK-IN-17: Potent JAK inhibitor for studying ocular, skin, and respiratory diseases."</p>
    Formula:C33H38F2N6O8
    Color and Shape:Solid
    Molecular weight:684.69
  • BT-GSI


    <p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma &amp; anti-resorptive for multiple myeloma/bone disease research.</p>
    Formula:C26H46BrN5O10P2
    Color and Shape:Solid
    Molecular weight:730.52
  • JAK-IN-1

    CAS:
    <p>JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.</p>
    Formula:C20H24N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.44
  • Tubulin/JAK2-IN-1

    CAS:
    <p>Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significant</p>
    Formula:C22H20N6O3
    Color and Shape:Solid
    Molecular weight:416.43
  • Yhhu-3792 hydrochloride

    CAS:
    <p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>
    Formula:C24H25ClN4O2
    Color and Shape:Solid
    Molecular weight:436.93
  • STAT3-IN-B9

    CAS:
    <p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>
    Formula:C20H13NO5S
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:379.39
  • A 1070722

    CAS:
    A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.
    Formula:C17H13F3N4O2
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:362.31
  • JW 67

    CAS:
    <p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>
    Formula:C21H18N2O6
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:394.38
  • Ginsenoside Rk1

    CAS:
    <p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>
    Formula:C42H70O12
    Purity:98.46% - 99.13%
    Color and Shape:Solid
    Molecular weight:767
  • TP0427736

    CAS:
    TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.
    Formula:C14H10N4S2
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:298.39
  • ML115

    CAS:
    <p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>
    Formula:C15H15ClN2O4
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:322.74
  • MRK-560

    CAS:
    MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.
    Formula:C19H17ClF5NO4S2
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:517.92
  • ROCK-IN-1

    CAS:
    <p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>
    Formula:C20H18FN3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:335.37
  • GNE-7883

    CAS:
    <p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>
    Formula:C28H29FN6O2
    Purity:97.61%
    Color and Shape:Solid
    Molecular weight:500.57
  • Gossypolone

    CAS:
    <p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>
    Formula:C30H26O10
    Purity:96.66%
    Color and Shape:Solid
    Molecular weight:546.52
  • H-1152 dihydrochloride

    CAS:
    <p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>
    Formula:C16H23Cl2N3O2S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:392.34
  • STAT6-IN-2

    CAS:
    <p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>
    Formula:C28H31N5O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:469.58