Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase(60 products)
- Hedgehog/Smoothened(49 products)
- Hippo pathway(7 products)
- JAK(244 products)
- Porcupine(9 products)
- ROCK(62 products)
- STAT(98 products)
- Stem Cells(232 products)
- TGF-beta/Smad(53 products)
- Wnt/beta-catenin(62 products)
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Found 513 products of "Stem Cell and Derivatives"
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Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
CAS:Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491.Formula:C88H138N20O34P2Purity:98%Color and Shape:SolidMolecular weight:2082.1CIA-1 (Free base)
CAS:CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Formula:C17H19N3O2SPurity:99%Color and Shape:SolidMolecular weight:329.421(R),2(S)-epoxy Cannabidiol
CAS:1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46PROTAC TYK2 degradation agent1
CAS:PROTAC TYK2 Agent1 selectively degrades TYK2, with a 14 nM DC50, for autoimmune research.Formula:C55H69N13O7SPurity:98%Color and Shape:SolidMolecular weight:1056.28AS2553627
CAS:AS2553627 is a JAK inhibitor. AS2553627 prevents chronic rejection in rat cardiac allografts.Formula:C18H19N5OColor and Shape:SolidMolecular weight:321.38JAK1/TYK2-IN-1
CAS:JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).Formula:C18H20F3N7OColor and Shape:SolidMolecular weight:407.401RBPJ Inhibitor-1
CAS:RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cellFormula:C17H14FN3O2Purity:99.79%Color and Shape:SoildMolecular weight:311.31Ref: TM-T35566
1mg38.00€2mg50.00€5mg84.00€10mg130.00€25mg215.00€50mg371.00€100mg537.00€1mL*10mM (DMSO)93.00€JAK-IN-15
CAS:JAK-IN-15 is a JAK inhibitor. WO2016119700A1 (Compound 15).Formula:C22H23FN4O3SColor and Shape:SolidMolecular weight:442.51JAK-STAT Compound Library
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L3700
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireTYK2 activator-1
TYK2activator-1 (16b) is a TYK2 activator with an EC50 value of 1.78 μM. It inhibits JAK2 and JAK3 with IC50 values of 6.8 μM and 6.3 μM, respectively.Formula:C23H21FN4O2Color and Shape:SolidMolecular weight:404.16485JAK3-IN-15
JAK3-IN-15 (compound 22) is a JAK3 inhibitor that reduces the secretion of p-JAK3 induced by LPS. It is utilized in research for rheumatoid arthritis.Color and Shape:Odour SolidGSK3-IN-1
CAS:GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.
Formula:C14H10ClN3OSPurity:99.66%Color and Shape:SolidMolecular weight:303.77FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Color and Shape:LiquidNotch 1 TFA
Notch 1 TFA encodes a member of the NOTCH family of proteins.Formula:C64H98N15F3O25S3Purity:98%Color and Shape:SolidMolecular weight:1614.81SJ10542
CAS:SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.Formula:C41H46N12O5SColor and Shape:SolidMolecular weight:818.95HC-258
CAS:HC-258 is a direct TEAD inhibitor covalent Cys380, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 MDA-MB-231.Formula:C20H24N2O2Color and Shape:SolidMolecular weight:324.42FRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFormula:C22H22ClN5O2Color and Shape:SolidMolecular weight:423.9Epigenetics Compound Library
Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for newColor and Shape:Odour SolidRef: TM-L1200
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireSJ1008030
CAS:SJ1008030, a JAK2 PROTAC, degrades JAK2; EC50: 5.4 nM, IC50: 32.09 nM in MHH-CALL-4 cells for leukemia research.
Formula:C42H43N13O7SColor and Shape:SolidMolecular weight:873.94TGFβRI-IN-7
TGFβRI-IN-7 (compound 16W) is a potent inhibitor of TGFβRI. It effectively inhibits the phosphorylation of SMAD2/3 and reduces the viability of H22 cells, with IC50 values of 12 nM and 65 nM, respectively. In an H22 cell xenograft model, TGFβRI-IN-7 exhibits antitumor efficacy with a TGI of 79.6%.Formula:C27H32N6O2Color and Shape:SolidMolecular weight:472.582
