Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase(67 products)
- Hedgehog/Smoothened(49 products)
- Hippo pathway(7 products)
- JAK(243 products)
- Porcupine(8 products)
- ROCK(62 products)
- STAT(103 products)
- Stem Cells(129 products)
- TGF-beta/Smad(70 products)
- Wnt/beta-catenin(64 products)
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Found 434 products for "Stem Cell and Derivatives".
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SPL-707
CAS:SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).Formula:C27H28FN5O4Purity:98%Color and Shape:SolidMolecular weight:505.54γ-Secretase modulator 10
CAS:γ-Secretase modulator 10 is a novel γ-secretase modulator.Formula:C25H23F3N4O2Color and Shape:SolidMolecular weight:468.48MMT3-72
CAS:MMT3-72 is a weak JAK1 inhibitor with superior efficacy and reduced p-STAT3 in DSS-induced colitis [1].Formula:C40H42N8O9SMolecular weight:810.87LSKL TFA
CAS:LSKL TFA (H-Leu-Ser-Lys-Leu-NH2 TFA) is a TGF-尾1 antagonist that inhibits TSP-1 binding to LAP and reduces renal interstitial fibrosis and liver fibrosis.Formula:C23H43F3N6O7Purity:99.33%Color and Shape:SolidMolecular weight:572.62Axltide
CAS:Axltide mimics mouse Insulin receptor substrate 1, amino acids 979-989 with sequence KKSRGDYMTMQIG.Formula:C63H107N19O20S2Purity:98%Color and Shape:SolidMolecular weight:1514.77Povorcitinib phosphate
CAS:Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.Formula:C23H25F5N7O5PPurity:99.57%Color and Shape:SolidMolecular weight:605.45Ref: TM-T39113L
1mg46.00€5mg96.00€1mL*10mM (DMSO)128.00€10mg145.00€25mg236.00€50mg339.00€100mg460.00€200mg622.00€Myostatin inhibitory peptide 2 TFA
Myostatin Inhibitory Peptide 2 (compd 2) TFA is a potent inhibitor of muscle growth suppressant with a dissociation constant (Kd) of 35.9 nM. It is utilized in the study of muscle atrophy diseases.Color and Shape:Odour SolidYAP-IN-1
YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 μM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of autophagosomes with lysosomes and decreases autophagy levels without affecting lysosomal function. YAP-IN-1 shows potential for cancer research, including in hepatocellular carcinoma and breast cancer.Color and Shape:Odour SolidJAK1/STAT3-IN-1
JAK1/STAT3-IN-1 (compound 4f) functions as an anti-atopic dermatitis (AD) agent by inhibiting the JAK1/STAT3 signaling pathway. It has an IC50 value of 2.17 μM for inhibiting NO production. Additionally, JAK1/STAT3-IN-1 improves skin conditions in AD-like mice by reducing inflammatory infiltration, suppressing the expression of p-JAK1/JAK1 and p-STAT3/STAT3, and alleviating the hyperimmune response induced by MC903 (Calcipotriol).Formula:C30H33FN4O3SColor and Shape:SolidMolecular weight:548.67PROTAC TYK2 degradation agent1
CAS:PROTAC TYK2 Agent1 selectively degrades TYK2, with a 14 nM DC50, for autoimmune research.Formula:C55H69N13O7SPurity:98%Color and Shape:SolidMolecular weight:1056.28Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Color and Shape:Odour SolidRef: TM-L2200
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireJAK2-IN-10
CAS:JAK2-IN-10 is a potent inhibitor of JAK2v617f, with an IC50 value of ≤10 nM.Formula:C33H33D3FN9O2Color and Shape:SolidMolecular weight:612.71Tubastatin
CAS:Tubastatin inhibits TGF-β1-induced S6K phosphorylation, HIF-1α expression and VEG F expression.Formula:C21H22N2O2Purity:98.23%Color and Shape:SolidMolecular weight:334.41TEAD-IN-16
TEAD-IN-16 (compound BC-011) is a potent inhibitor of TEAD, with an IC50 of 72.43 μM. This compound plays a significant role in cancer research.Formula:C16H14F3NO3Color and Shape:SolidMolecular weight:325.09258Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidRef: TM-L1600
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireFRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFormula:C22H22ClN5O2Color and Shape:SolidMolecular weight:423.9LY2382770
LY2382770 is a human monoclonal antibody (mAb) that specifically targets TGFB1. It is utilized in the study of diabetic nephropathy.PSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.Formula:C20H18ClFN2O3SColor and Shape:SolidMolecular weight:420.885β-Cholanic acid
CAS:5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.Formula:C24H40O2Purity:98.91% - 99.89%Color and Shape:White SolidMolecular weight:360.57Epigenetics Compound Library
A collection of xnum wine components, suitable for high-throughput and high-content screening.Color and Shape:Odour SolidRef: TM-L1200
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquire
