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Fibroblast Growth Factor Receptor (FGFR)
PD 173074
CAS:219580-11-7
Formula:
C28H41N7O3
Purity:
>95.0%(HPLC)
Color and Shape:
White to Yellow to Orange powder to crystal
Molecular weight:
523.68
Estimated delivery in United States, on Thursday 27 Jan 2022
PD-161570
CAS:192705-80-9
Formula:
C26H35Cl2N7O
Purity:
>98.0%(HPLC)
Color and Shape:
White to Light yellow powder to crystal
Molecular weight:
532.51
Estimated delivery in United States, on Thursday 27 Jan 2022
Regorafenib
CAS:755037-03-7
Formula:
C21H15ClF4N4O3
Purity:
>98.0%(HPLC)
Color and Shape:
White to Light yellow to Light orange powder to crystal
Molecular weight:
482.82
Estimated delivery in United States, on Thursday 27 Jan 2022
CH5183284
CAS:1265229-25-1
CH5183284 is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 …
Formula:
C20H16N6O
Purity:
95.28%
Color and Shape:
solid
Molecular weight:
356.38
Estimated delivery in United States, on Monday 7 Feb 2022
Dovitinib
CAS:405169-16-6
Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 …
Formula:
C21H21FN6O
Purity:
99.78%
Color and Shape:
solid
Molecular weight:
392.43
Estimated delivery in United States, on Monday 7 Feb 2022
PD168393
CAS:194423-15-9
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, …
Formula:
C17H13BrN4O
Purity:
99.04%
Color and Shape:
solid
Molecular weight:
369.22
Estimated delivery in United States, on Monday 7 Feb 2022
FIIN2
CAS:1633044-56-0
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 …
Formula:
C35H38N8O4
Purity:
99.65%
Color and Shape:
Crystalline Solid
Molecular weight:
634.73
Estimated delivery in United States, on Monday 7 Feb 2022
Brivanib Alaninate
CAS:649735-63-7
Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) …
Formula:
C22H24FN5O4
Purity:
99.66%
Color and Shape:
solid
Molecular weight:
441.46
Estimated delivery in United States, on Monday 7 Feb 2022
ZM 323881 hydrochloride
CAS:193000-39-4
ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor.
Formula:
C22H19ClFN3O2
Molecular weight:
411.86
Estimated delivery in United States, on Monday 7 Feb 2022
PD166866
CAS:192705-79-6
PD166866 is a selective FGFR tyrosine kinase inhibitor.
Formula:
C20H24N6O3
Purity:
99.98%
Color and Shape:
solid
Molecular weight:
396.45
Estimated delivery in United States, on Monday 7 Feb 2022
S49076 HCl
CAS:1265966-31-1
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation …
Formula:
C22H18ClN3O5
Purity:
98.0%
Color and Shape:
Solid
Molecular weight:
439.85
Estimated delivery in United States, on Monday 7 Feb 2022
KI8751
CAS:228559-41-9
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
Formula:
C24H18F3N3O4
Purity:
99.73%
Color and Shape:
solid
Molecular weight:
469.41
Estimated delivery in United States, on Monday 7 Feb 2022
S49076
CAS:1265965-22-7
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of …
Formula:
C22H22N4O4S
Purity:
97.40%
Color and Shape:
Solid
Molecular weight:
438.13
Estimated delivery in United States, on Monday 7 Feb 2022
PHA680632
CAS:398493-79-3
PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of …
Formula:
C28H35N7O2
Purity:
99.03%
Molecular weight:
501.62
Estimated delivery in United States, on Monday 7 Feb 2022
LY2874455
CAS:1254473-64-7
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
Formula:
C21H19Cl2N5O2
Purity:
99.46%
Color and Shape:
solid
Molecular weight:
444.31
Estimated delivery in United States, on Monday 7 Feb 2022
SKLB 610
CAS:1125780-41-7
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a …
Formula:
C21H16F3N3O3
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
415.37
Estimated delivery in United States, on Monday 7 Feb 2022
Tyrphostin AG 1296
CAS:146535-11-7
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity …
Formula:
C16H14N2O2
Purity:
99.68%
Color and Shape:
solid
Molecular weight:
266.29
Estimated delivery in United States, on Monday 7 Feb 2022
TAK632
CAS:1228591-30-7
TAK-632 is a potent pan-Raf inhibitor.
Formula:
C27H18F4N4O3S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
554.52
Estimated delivery in United States, on Monday 7 Feb 2022
FIIN3
CAS:1637735-84-2
FIIN-3 is an irreversible inhibitor of FGFR.
Formula:
C34H36Cl2N8O4
Purity:
97.63%
Color and Shape:
Solid
Molecular weight:
691.61
Estimated delivery in United States, on Monday 7 Feb 2022
Dovitinib Dilactic Acid
CAS:852433-84-2
Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a …
Formula:
C21H21FN6O·2C3H6O3
Purity:
98.0%
Color and Shape:
solid
Molecular weight:
572.59
Estimated delivery in United States, on Monday 7 Feb 2022
FGFR4-IN-1
CAS:1708971-72-5
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
Formula:
C24H27N7O5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
493.52
Estimated delivery in United States, on Monday 7 Feb 2022
AG473
CAS:133550-22-8
AG473 is an inhibitor of EGFR in human A431 cells.
Formula:
C16H11NO3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
265.26
Estimated delivery in United States, on Monday 7 Feb 2022
Mubritinib
CAS:366017-09-6
Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
Formula:
C25H23F3N4O2
Purity:
99.57%
Color and Shape:
solid
Molecular weight:
468.47
Estimated delivery in United States, on Monday 7 Feb 2022
PD173074
CAS:219580-11-7
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 …
Formula:
C28H41N7O3
Purity:
99.33%
Color and Shape:
Yellow Solid
Molecular weight:
523.67
Estimated delivery in United States, on Monday 7 Feb 2022
Orantinib
CAS:252916-29-3
TSU-68, a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits …
Formula:
C18H18N2O3
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
310.35
Estimated delivery in United States, on Monday 7 Feb 2022
Pazopanib HCl
CAS:635702-64-6
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, …
Formula:
C21H23N7O2S·HCl
Purity:
99.69%
Color and Shape:
solid
Molecular weight:
473.98
Estimated delivery in United States, on Monday 7 Feb 2022
Brivanib
CAS:649735-46-6
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against …
Formula:
C19H19FN4O3
Purity:
98.0%
Color and Shape:
solid
Molecular weight:
370.38
Estimated delivery in United States, on Monday 7 Feb 2022
Sucralfate
CAS:54182-58-0
Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of …
Formula:
C12H54Al16O75S8
Purity:
98.0%
Color and Shape:
White Amorphous Powder
Molecular weight:
2086.75
Estimated delivery in United States, on Monday 7 Feb 2022
FGFR4-IN-4
CAS:2230973-67-6
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
Formula:
C28H32Cl2N6O5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
603.5
Estimated delivery in United States, on Monday 7 Feb 2022
Derazantinib
CAS:1234356-69-4
Derazantinib (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 …
Formula:
C29H29FN4O
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
468.57
Estimated delivery in United States, on Monday 7 Feb 2022
Infigratinib
CAS:872511-34-7
Infigratinib (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold …
Formula:
C26H31Cl2N7O3
Purity:
98.46%
Color and Shape:
solid
Molecular weight:
560.48
Estimated delivery in United States, on Monday 7 Feb 2022
ASP-5878
CAS:1453208-66-6
ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with …
Formula:
C18H19F2N5O4
Purity:
99.80%
Color and Shape:
solid
Molecular weight:
407.38
Estimated delivery in United States, on Monday 7 Feb 2022
SU5402
CAS:215543-92-3
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 …
Formula:
C17H16N2O3
Purity:
99.08%
Color and Shape:
Yellow-Green Solid
Molecular weight:
296.32
Estimated delivery in United States, on Monday 7 Feb 2022
DGY-06-116
DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value …
Formula:
C32H33ClN8O2
Molecular weight:
597.11
Estimated delivery in United States, on Monday 7 Feb 2022
Sulfatinib
CAS:1816307-67-1
Sulfatinib may be a potent drug for cancer. It inhibits KDR and FGFR1 enzymatic activity. …
Formula:
C24H28N6O3S
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
480.59
Estimated delivery in United States, on Monday 7 Feb 2022
BLU9931
CAS:1538604-68-0
BLU9931 is the first selective small molecule inhibitor of FGFR4.
Formula:
C26H22Cl2N4O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
509.38
Estimated delivery in United States, on Monday 7 Feb 2022
CP-547632 hydrochloride
CAS:252003-71-7
CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases …
Formula:
C20H25BrClF2N5O3S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
568.86
Estimated delivery in United States, on Monday 7 Feb 2022
TAS120
CAS:1448169-71-8
TAS-120 is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.
Formula:
C22H22N6O3
Purity:
97.34%
Color and Shape:
Solid
Molecular weight:
418.45
Estimated delivery in United States, on Monday 7 Feb 2022
Amlexanox
CAS:68302-57-8
Amlexanox is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, …
Formula:
C16H14N2O4
Purity:
98.00%
Color and Shape:
White Crystalline Solid
Molecular weight:
298.29
Estimated delivery in United States, on Monday 7 Feb 2022
ACTB1003
CAS:939805-30-8
ACTB-1003 is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).
Formula:
C27H26F5N7O3
Purity:
99.26%
Color and Shape:
solid
Molecular weight:
591.54
Estimated delivery in United States, on Monday 7 Feb 2022
CHIR98014
CAS:252935-94-7
CHIR-98014 is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in …
Formula:
C20H17Cl2N9O2
Purity:
97.09%
Molecular weight:
486.31
Estimated delivery in United States, on Monday 7 Feb 2022
Danusertib
CAS:827318-97-8
Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Danusertib binds to and inhibits …
Formula:
C26H30N6O3
Purity:
98.44%
Color and Shape:
White Powder
Molecular weight:
474.55
Estimated delivery in United States, on Monday 7 Feb 2022
Dovitinib lactate
CAS:692737-80-7
Dovitinib lactate(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 …
Formula:
C24H27FN6O4
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
482.51
Estimated delivery in United States, on Monday 7 Feb 2022
SSR128129E
CAS:848318-25-2
SSR128129E is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other …
Formula:
C18H15N2O4·Na
Purity:
98.79%
Color and Shape:
solid
Molecular weight:
346.31
Estimated delivery in United States, on Monday 7 Feb 2022
Roblitinib
CAS:1708971-55-4
FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic …
Formula:
C25H30N8O4
Purity:
97.27%
Color and Shape:
Solid
Molecular weight:
506.57
Estimated delivery in United States, on Monday 7 Feb 2022
SU11274
CAS:658084-23-2
SU11274(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFR, EGFR …
Formula:
C28H30CIN5O4S
Purity:
98.62%
Color and Shape:
Orange Powder
Molecular weight:
568.09
Estimated delivery in United States, on Monday 7 Feb 2022
Erdafitinib
CAS:1346242-81-6
Erdafitinib is a quinoxaline derivative compound, acts on FGFR1/2/3/4.
Formula:
C25H30N6O2
Purity:
99.04%
Color and Shape:
solid
Molecular weight:
446.55
Estimated delivery in United States, on Monday 7 Feb 2022
Dovitinib Lactate
CAS:915769-50-5
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly …
Formula:
C24H27FN6O4
Purity:
99.17%
Molecular weight:
482.51
Estimated delivery in United States, on Monday 7 Feb 2022
Ponatinib
CAS:943319-70-8
Ponatinib is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFR, VEGFR2, …
Formula:
C29H27F3N6O
Purity:
99.58%
Color and Shape:
solid
Molecular weight:
532.56
Estimated delivery in United States, on Monday 7 Feb 2022
Nintedanib Ethanesulfonate Salt
CAS:656247-18-6
BIBF 1120 esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFR/
Formula:
C31H33N5O4C2H6O3S
Purity:
99.96%
Color and Shape:
solid
Molecular weight:
649.76
Estimated delivery in United States, on Monday 7 Feb 2022
ODM-203
CAS:1430723-35-5
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor …
Formula:
C26H21F2N5O2S
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
505.54
Estimated delivery in United States, on Monday 7 Feb 2022
SU4984
CAS:186610-89-9
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 …
Formula:
C20H19N3O2
Molecular weight:
333.38
Estimated delivery in United States, on Monday 7 Feb 2022
Formononetin
CAS:485-72-3
Formononetin is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
Formula:
C16H12O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
268.27
Estimated delivery in United States, on Monday 7 Feb 2022
BLU554
CAS:1707289-21-1
BLU-554 is a potent inhibitor of fibroblast growth factor receptor 4 (FGFR4).
Formula:
C24H24Cl2N4O4
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
503.38
Estimated delivery in United States, on Monday 7 Feb 2022
Pemigatinib
CAS:1513857-77-6
Pemigatinib is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 …
Formula:
C24H27F2N5O4
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
487.5
Estimated delivery in United States, on Monday 7 Feb 2022
SSR128129E free acid
CAS:848463-13-8
SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM …
Formula:
C18H16N2O4
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
324.33
Estimated delivery in United States, on Monday 7 Feb 2022
Ferulic Acid
CAS:1135-24-6
Ferulic Acid is a highly abundant phenolic phytochemical and a type of organic compound found …
Formula:
C10H10O4
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
194.19
Estimated delivery in United States, on Monday 7 Feb 2022
Rogaratinib
CAS:1443530-05-9
Rogaratinib is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an …
Formula:
C23H26N6O3S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
466.56
Estimated delivery in United States, on Monday 7 Feb 2022
PHA665752
CAS:477575-56-7
PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for …
Formula:
C32H34Cl2N4O4S
Purity:
99.35%
Color and Shape:
solid
Molecular weight:
641.61
Estimated delivery in United States, on Monday 7 Feb 2022
AZD4547
CAS:1035270-39-3
AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).
Formula:
C26H33N5O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
463.57
Estimated delivery in United States, on Monday 7 Feb 2022
Alofanib
CAS:1612888-66-0
Alofanib is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on …
Formula:
C19H15N3O6S
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
413.4
Estimated delivery in United States, on Monday 7 Feb 2022
PRN1371
CAS:1802929-43-6
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 …
Formula:
C26H30Cl2N6O4
Purity:
99.72%
Color and Shape:
solid
Molecular weight:
561.46
Estimated delivery in United States, on Monday 7 Feb 2022
H3B-6527
CAS:1702259-66-2
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic …
Formula:
C29H34Cl2N8O4
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
629.53
Estimated delivery in United States, on Monday 7 Feb 2022
SUN 11602
CAS:704869-38-5
SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics …
Formula:
C26H37N5O2
Color and Shape:
solid
Molecular weight:
451.61
Estimated delivery in United States, on Monday 7 Feb 2022
Lenvatinib
CAS:417716-92-8
Lenvatinib is a Kinase Inhibitor. The mechanism of action of lenvatinib is as a Receptor …
Formula:
C21H19ClN4O4
Purity:
98.57%
Color and Shape:
solid
Molecular weight:
426.85
Estimated delivery in United States, on Monday 7 Feb 2022
