PDGFR
PDGFR (platelet-derived growth factor receptor) inhibitors are compounds that block the signaling of PDGFR, a receptor involved in cell growth, proliferation, and angiogenesis. PDGFR plays a significant role in the development of the blood vessels that supply tumors. Inhibiting PDGFR can therefore prevent angiogenesis, making these inhibitors valuable in cancer therapy. At CymitQuimica, we provide a selection of high-quality PDGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 127 products of "PDGFR"
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N-(p-Coumaroyl) serotonin
CAS:N-(p-Coumaroyl) Serotonin, from safflower seeds, has antioxidant, antitumor properties and improves vascular health.Formula:C19H18N2O3Purity:98.10% - 98.89%Color and Shape:SolidMolecular weight:322.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.
Formula:C17H16N2OPurity:>99.99%Color and Shape:SolidMolecular weight:264.32Seralutinib
CAS:Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Formula:C27H27N5O3Purity:99.09%Color and Shape:SolidMolecular weight:469.54Ref: TM-T8900
1mg47.00€2mg62.00€5mg92.00€10mg137.00€25mg236.00€50mg313.00€100mg497.00€1mL*10mM (DMSO)92.00€PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purity:98.45% - 99.93%Color and Shape:SolidMolecular weight:319.36PD-089828
CAS:PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Formula:C18H18Cl2N6OPurity:97.39%Color and Shape:SolidMolecular weight:405.28Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07% - 99.62%Color and Shape:SolidMolecular weight:510.36Ref: TM-T8482
1mg74.00€2mg97.00€5mg165.00€10mg274.00€25mg432.00€50mg692.00€100mg1,121.00€200mg1,539.00€1mL*10mM (DMSO)202.00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Ref: TM-T8491
1mg101.00€2mg142.00€5mg215.00€10mg340.00€25mg583.00€50mg842.00€100mg1,144.00€200mg1,521.00€1mL*10mM (DMSO)236.00€CP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormula:C24H27N5O2Purity:99.62% - 99.88%Color and Shape:SolidMolecular weight:417.5Ref: TM-T6091
1mg49.00€2mg63.00€5mg90.00€10mg170.00€25mg334.00€50mg512.00€100mg737.00€500mg1,521.00€1mL*10mM (DMSO)108.00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formula:C26H27FN10Purity:96.59% - 99.7%Color and Shape:SolidMolecular weight:498.56Ref: TM-T5109
1mg38.00€5mg80.00€10mg120.00€25mg235.00€50mg354.00€100mg588.00€200mg833.00€1mL*10mM (DMSO)175.00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurity:99.43% - 99.98%Color and Shape:SolidMolecular weight:649.76Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formula:C20H17F3N4O3Purity:99.34%Color and Shape:SolidMolecular weight:418.37Ref: TM-T4191
1mg37.00€2mg52.00€5mg79.00€10mg101.00€25mg177.00€50mg268.00€100mg385.00€1mL*10mM (DMSO)87.00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:98.97% - 99.88%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg44.00€5mg90.00€10mg145.00€25mg268.00€50mg439.00€100mg700.00€200mg954.00€1mL*10mM (DMSO)90.00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:98.13%Color and Shape:SolidMolecular weight:442.48Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formula:C29H29F3N8OPurity:99.39% - 99.95%Color and Shape:SolidMolecular weight:562.59Ref: TM-T4320
1mg34.00€5mg63.00€10mg82.00€25mg120.00€50mg155.00€100mg259.00€200mg388.00€500mg642.00€1mL*10mM (DMSO)82.00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormula:C18H22N2OPurity:98.21% - 99.87%Color and Shape:Yellow SolidMolecular weight:282.38SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurity:99.92%Color and Shape:SolidMolecular weight:532.51Ref: TM-T23127
1mg34.00€5mg96.00€10mg141.00€25mg289.00€50mg465.00€100mg662.00€200mg888.00€1mL*10mM (DMSO)118.00€Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45Sennoside B
CAS:Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.Formula:C42H38O20Purity:92.85% - 98.92%Color and Shape:Light Yellow CrystalMolecular weight:862.74
