Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purity:94.54% - 99.86%Color and Shape:SolidMolecular weight:338.35Ref: TM-T6S1683
5mg42.00€10mg52.00€25mg88.00€50mg149.00€100mg212.00€200mg314.00€1mL*10mM (DMSO)52.00€Cilofexor tromethamine
CAS:Cilofexor (GS-9674), a nonsteroidal FXR agonist, reduces cholestasis and liver damage in PSC, showing safety and efficacy in trials.Formula:C32H33Cl3N4O8Color and Shape:SolidMolecular weight:707.99Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.36Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purity:98.97% - 99.62%Color and Shape:SolidMolecular weight:246.3Ref: TM-TQ0165
1mg84.00€2mg123.00€5mg227.00€10mg341.00€25mg492.00€50mg655.00€100mg982.00€200mg1,314.00€1mL*10mM (DMSO)294.00€Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formula:C15H18O8Purity:98.81% - 99.92%Color and Shape:White SolidMolecular weight:326.30Amsacrine gluconate
CAS:Amsacrine gluconate: an aminoacridine with anticancer properties, possibly works by intercalating DNA and inhibiting topoisomerase II.Formula:C27H31N3O10SColor and Shape:SolidMolecular weight:589.62Apocynin
CAS:Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).Formula:C9H10O3Purity:99.71% - 99.98%Color and Shape:Yellowish To Brown PowderMolecular weight:166.17HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formula:C23H22N4O3S2Purity:99.77% - 99.86%Color and Shape:SolidMolecular weight:466.58Ref: TM-T6855
1mg35.00€2mg48.00€5mg72.00€10mg96.00€25mg187.00€50mg283.00€100mg439.00€1mL*10mM (DMSO)74.00€ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formula:C22H24Cl2N2O4Purity:97.86% - 99.27%Color and Shape:SolidMolecular weight:451.34Binimetinib
CAS:Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formula:C17H15BrF2N4O3Purity:98.03% - >99.99%Color and Shape:SolidMolecular weight:441.23Reparixin
CAS:Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.Formula:C14H21NO3SPurity:98% - 99.89%Color and Shape:SolidMolecular weight:283.39Ref: TM-T4163
5mg48.00€10mg62.00€25mg120.00€50mg187.00€100mg301.00€200mg449.00€1mL*10mM (DMSO)111.00€Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formula:C17H20O5Purity:99.61% - 99.72%Color and Shape:SolidMolecular weight:304.34Ref: TM-TN6735
1mg96.00€5mg205.00€10mg268.00€25mg465.00€50mg662.00€100mg888.00€1mL*10mM (DMSO)203.00€Britannin
CAS:Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.Formula:C19H26O7Purity:98% - 99.98%Color and Shape:SolidMolecular weight:366.41Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purity:95.37% - 99.82%Color and Shape:Dark Green To Black SolidMolecular weight:718.79Ref: TM-T3112
1mg38.00€2mg49.00€5mg80.00€10mg109.00€25mg213.00€50mg346.00€100mg437.00€1mL*10mM (DMSO)114.00€Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74Hydroxyprogesterone caproate
CAS:Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.Formula:C27H40O4Purity:99.70%Color and Shape:White Or Almost White Crystalline PowerMolecular weight:428.60Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69BMS-582949 hydrochloride
CAS:The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).Formula:C22H27ClN6O2Purity:97.57% - 98.75%Color and Shape:SolidMolecular weight:442.95Ref: TM-T3462
1mg34.00€5mg67.00€10mg96.00€25mg161.00€50mg250.00€100mg371.00€200mg523.00€1mL*10mM (DMSO)73.00€Tazarotene
CAS:Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formula:C21H21NO2SPurity:97.01% - 99.14%Color and Shape:White SolidMolecular weight:351.46Ref: TM-T6696
5mg35.00€10mg50.00€25mg84.00€50mg140.00€100mg244.00€200mg315.00€500mg533.00€1mL*10mM (DMSO)52.00€Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purity:96.39% - 99.29%Color and Shape:SolidMolecular weight:394.42BIA 10-2474
CAS:BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formula:C16H20N4O2Purity:99.27%Color and Shape:SolidMolecular weight:300.36Pirarubicin
CAS:Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.Formula:C32H37NO12Purity:97.80% - 99.15%Color and Shape:Red Crystalline PowderMolecular weight:627.64kaempferide
CAS:kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formula:C16H12O6Purity:98.4% - 99.66%Color and Shape:SolidMolecular weight:300.26SR12813
CAS:SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Formula:C24H42O7P2Purity:99.43%Color and Shape:SolidMolecular weight:504.53GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formula:C21H27N7O3Purity:98.07% - 99.77%Color and Shape:SolidMolecular weight:425.48Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurity:99.45%Color and Shape:SolidMolecular weight:474.91Ref: TM-T4398
2mg34.00€5mg50.00€10mg79.00€25mg130.00€50mg216.00€100mg323.00€200mg447.00€1mL*10mM (DMSO)55.00€Cabergoline diphosphate
CAS:Cabergoline, a D2 receptor agonist, treats prolactinomas by normalizing prolactin levels.Formula:C26H43N5O10P2Color and Shape:SolidMolecular weight:647.6PF-4708671
CAS:PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formula:C19H21F3N6Purity:99.48% - 99.98%Color and Shape:SolidMolecular weight:390.41Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83Ref: TM-T3419
2mg34.00€5mg50.00€10mg84.00€25mg145.00€50mg205.00€100mg289.00€200mg432.00€1mL*10mM (DMSO)65.00€BI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formula:C19H23F2N5O2Purity:98.51% - 99.43%Color and Shape:SolidMolecular weight:391.42VLX600
CAS:VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formula:C17H15N7Purity:98.62%Color and Shape:SolidMolecular weight:317.35Ganoderic acid A
CAS:Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formula:C30H44O7Purity:99.31% - ≥95%Color and Shape:SolidMolecular weight:516.67Ref: TM-T6S1141
1mg44.00€5mg92.00€10mg152.00€25mg236.00€50mg354.00€100mg518.00€1mL*10mM (DMSO)104.00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formula:C23H28N4O2Purity:96.78% - 99.76%Color and Shape:SolidMolecular weight:392.49Bromocriptine mesylate
CAS:Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)Formula:C33H44BrN5O8SPurity:99.85% - 99.96%Color and Shape:White SolidMolecular weight:750.7Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purity:98.92% - 99.67%Color and Shape:White Crystal PowderMolecular weight:608.72Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purity:99.56% - >99.99%Color and Shape:SolidMolecular weight:425.42Ref: TM-T6130
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg208.00€50mg313.00€100mg465.00€1mL*10mM (DMSO)87.00€SR9011
CAS:SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).Formula:C23H31ClN4O3SPurity:99.64% - 99.65%Color and Shape:SolidMolecular weight:479.042-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:302.41Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33Ref: TM-T1847
5mg34.00€10mg50.00€25mg78.00€50mg107.00€100mg166.00€200mg236.00€500mg398.00€1mL*10mM (DMSO)50.00€Fendiline
CAS:Fendiline: coronary vasodilator, calcium blocker, potential antiarrhythmic/antianginal.Formula:C23H25NColor and Shape:SolidMolecular weight:315.45DMOG
CAS:DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formula:C38H35N5O6S2Purity:99.80% - >99.99%Color and Shape:White SolidMolecular weight:721.84Ref: TM-T2694
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg207.00€50mg404.00€100mg592.00€1mL*10mM (DMSO)105.00€Adezmapimod
CAS:Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formula:C21H16FN3OSPurity:99.42% - 99.93%Color and Shape:White SolidMolecular weight:377.43Heparin sodium salt
CAS:Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Formula:C9H20N3NaO3Purity:98%Color and Shape:SolidMolecular weight:241.267Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg40.00€2mg52.00€5mg84.00€10mg101.00€25mg202.00€50mg326.00€100mg520.00€1mL*10mM (DMSO)82.00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.50Gambogic Acid
CAS:Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.Formula:C38H44O8Purity:97.16% - 98.67%Color and Shape:SolidMolecular weight:628.75Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:98% - >99.99%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g583.00€5mg49.00€10mg62.00€25mg78.00€50mg92.00€100mg138.00€200mg215.00€500mg395.00€1mL*10mM (DMSO)56.00€Perifosine
CAS:Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formula:C25H52NO4PPurity:99.80 - >99.99%Color and Shape:SolidMolecular weight:461.66Atorvastatin strontium
CAS:Atorvastatin strontium lowers cholesterol, prevents heart disease, and treats dyslipidemia by inhibiting HMG-CoA reductase.Formula:C66H68F2N4O10SrColor and Shape:SolidMolecular weight:1202.9GANT 61
CAS:GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.
Formula:C27H35N5Purity:97.59% - >99.99%Color and Shape:SolidMolecular weight:429.6UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purity:99.82%Color and Shape:SolidMolecular weight:436.58Ref: TM-T17209
1mg34.00€2mg49.00€5mg71.00€10mg113.00€25mg230.00€50mg385.00€100mg575.00€1mL*10mM (DMSO)81.00€Dansylcadaverine
CAS:Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.Formula:C17H25N3O2SPurity:98.33% - 99.6%Color and Shape:SolidMolecular weight:335.46Pemetrexed disodium hemipenta hydrate
CAS:Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formula:C20H21N5O6·2NaH2OPurity:98.76%Color and Shape:SolidMolecular weight:518.43SD 0006
CAS:SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86Ref: TM-T7276
2mg35.00€5mg55.00€10mg86.00€25mg138.00€50mg215.00€100mg319.00€200mg447.00€1mL*10mM (DMSO)62.00€BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purity:95.10% - 99.3% （SEC-HPLC）Color and Shape:LiquidMolecular weight:144.6 kDaDacinostat
CAS:LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.Formula:C22H25N3O3Purity:95.28% - 97.88%Color and Shape:SolidMolecular weight:379.45Ref: TM-T2454
1mg50.00€2mg64.00€5mg104.00€10mg170.00€25mg305.00€50mg462.00€100mg668.00€500mg1,369.00€1mL*10mM (DMSO)104.00€PPQ-102
CAS:PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).Formula:C26H22N4O3Purity:98.80% - ≥95%Color and Shape:SolidMolecular weight:438.48Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
Myristoylated autocamtide-2-related inhibitory peptide acetate is a cell-permeable CaM kinase II inhibitor.Formula:C80H146N22O22Purity:97.03%Color and Shape:SolidMolecular weight:1768.15Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.4% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Ref: TM-T5574
1mg34.00€5mg50.00€10mg93.00€25mg152.00€50mg205.00€100mg289.00€200mg432.00€1mL*10mM (DMSO)55.00€SR-18292
CAS:SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.Formula:C23H30N2O2Purity:99.16% - 99.91%Color and Shape:SolidMolecular weight:366.5Ref: TM-T4353
2mg38.00€5mg57.00€10mg93.00€25mg170.00€50mg268.00€100mg424.00€500mg888.00€1mL*10mM (DMSO)67.00€SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Formula:C19H20FN5OPurity:99.13% - 99.68%Color and Shape:SolidMolecular weight:353.39Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1030.29CA77.1
CAS:CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).Formula:C16H12ClN3OPurity:99.50%Color and Shape:SolidMolecular weight:297.74Deoxypodophyllotoxin
CAS:Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Formula:C22H22O7Purity:99.65% - 99.84%Color and Shape:SolidMolecular weight:398.41Triptonide
CAS:Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formula:C20H22O6Purity:99.11% - 99.64%Color and Shape:White Crystalline PowderMolecular weight:358.39Ref: TM-T5S1058
1mg52.00€2mg74.00€5mg108.00€10mg158.00€25mg268.00€50mg409.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)133.00€Leonurine hydrochloride
CAS:Leonurine hydrochloride (SCM-198 hydrochloride) , a major alkaloid compound extracted from Leonurus japonicas Houtt.Formula:C14H22ClN3O5Purity:99.07% - 99.97%Color and Shape:SolidMolecular weight:347.79Ref: TM-T4080
5mg34.00€10mg50.00€25mg99.00€50mg130.00€100mg167.00€500mgTo inquire1mL*10mM (DMSO)To inquireRhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purity:98.11% - 98.58%Color and Shape:SolidMolecular weight:578.52palovarotene
CAS:Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).
Formula:C27H30N2O2Purity:97.88% - 98.05%Color and Shape:SolidMolecular weight:414.54C646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formula:C24H19N3O6Purity:98% - 99.21%Color and Shape:SolidMolecular weight:445.42Ref: TM-T2452
2mg46.00€5mg65.00€10mg92.00€25mg185.00€50mg360.00€100mg532.00€500mg1,144.00€1mL*10mM (DMSO)65.00€SB 239063
CAS:SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.
Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formula:C19H12ClN3O2Purity:98% - 99.90%Color and Shape:SolidMolecular weight:349.77Ref: TM-T2259
1mg38.00€2mg49.00€5mg80.00€10mg118.00€25mg197.00€50mg313.00€100mg492.00€500mg1,054.00€1mL*10mM (DMSO)88.00€Scriptaid
CAS:Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Formula:C18H18N2O4Purity:96.74% - 99.45%Color and Shape:SolidMolecular weight:326.35Ref: TM-T6980
5mg67.00€10mg92.00€25mg193.00€50mg358.00€100mg537.00€500mg1,134.00€1mL*10mM (DMSO)74.00€GW406108X(Z/E)
CAS:GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21Ref: TM-T9207L
1mg124.00€5mg271.00€10mg408.00€25mg612.00€50mg919.00€100mg1,234.00€1mL*10mM (DMSO)268.00€4E1rcat
CAS:4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formula:C28H18N2O6Purity:99.47%Color and Shape:SolidMolecular weight:478.45Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purity:97.169% - 99.59%Color and Shape:Dark Purple Crystalline PowderMolecular weight:651.94β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Formula:C15H14O3Purity:99.76% - 99.88%Color and Shape:SolidMolecular weight:242.27Alirocumab
CAS:Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.Purity:95% - 97.1% (SDS-PAGE); 96.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.2 kDaDAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formula:C23H26F2N2O4Purity:98.06% - 99.81%Color and Shape:White SolidMolecular weight:432.46Ref: TM-T6202
2mg38.00€5mg55.00€10mg94.00€25mg157.00€50mg264.00€100mg358.00€200mg490.00€1mL*10mM (DMSO)56.00€Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Formula:C54H92O23Purity:99.12% - 99.76%Color and Shape:SolidMolecular weight:1109.29SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Formula:C13H10BrN3O4Purity:98.16% - 99.85%Color and Shape:SolidMolecular weight:352.14Ref: TM-T1955
5mg48.00€10mg63.00€25mg120.00€50mg213.00€100mg383.00€200mg585.00€500mg888.00€1mL*10mM (DMSO)50.00€FC131 TFA (606968-52-9 free base)
CAS:FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hivFormula:C38H48F3N11O8Purity:99.39% - 99.67%Color and Shape:SolidMolecular weight:843.85ATI-2341 acetate(1337878-62-2 free base)
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.Formula:C106H182N26O27S2Purity:97.14%Color and Shape:SolidMolecular weight:2316.87GlyH-101
CAS:GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.Formula:C19H15Br2N3O3Purity:98.71% - 98.78%Color and Shape:SolidMolecular weight:493.15Ref: TM-T2451
1mg34.00€5mg71.00€10mg103.00€25mg210.00€50mg354.00€100mg530.00€200mg755.00€1mL*10mM (DMSO)80.00€MSX-122
CAS:MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).Formula:C16H16N6Purity:98.31% - 98.94%Color and Shape:SolidMolecular weight:292.34Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormula:C16H12O5Purity:96.26% - ≥95%Color and Shape:Pale-Yellow NeedlesMolecular weight:284.26Danirixin
CAS:Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).Formula:C19H21ClFN3O4SPurity:99.78% - >99.99%Color and Shape:SolidMolecular weight:441.9Ref: TM-T5193
1mg58.00€5mg105.00€10mg170.00€25mg318.00€50mg505.00€100mg713.00€200mg982.00€1mL*10mM (DMSO)102.00€Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormula:C21H23N3O5Purity:98% - 99.51%Color and Shape:SolidMolecular weight:397.42Ref: TM-T7130
1mg38.00€5mg80.00€10mg114.00€25mg200.00€50mg299.00€100mg442.00€500mg973.00€1mL*10mM (DMSO)88.00€PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formula:C20H13FN4O2Purity:98.65%Color and Shape:SolidMolecular weight:360.34AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purity:99.39%Color and Shape:SolidMolecular weight:896.07SB-265610
CAS:SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.Formula:C14H9BrN6OPurity:99.5%Color and Shape:SolidMolecular weight:357.16Ref: TM-T16850
1mg52.00€5mg113.00€10mg177.00€25mg356.00€50mg530.00€100mg758.00€500mg1,558.00€1mL*10mM (DMSO)124.00€ML339
CAS:ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.Formula:C26H32ClN3O5Purity:99.9%Color and Shape:SolidMolecular weight:502AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formula:C21H28ClN5Purity:98.38% - 98.57%Color and Shape:SolidMolecular weight:385.93CTCE 9908 acetate
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.Formula:C88H151N27O25Purity:98.47%Color and Shape:SolidMolecular weight:1987.31MSX-127
CAS:MSX-127 elicites positive response in peptide CXCR4.Formula:C16H24N2O4Purity:98.43%Color and Shape:SolidMolecular weight:308.37WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formula:C18H18N4Purity:99.42% - ≥95%Color and Shape:SolidMolecular weight:290.36
