DUB
DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.
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HBX 19818
CAS:1426944-49-1
HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).
Formula:
C25H28ClN3O
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
421.96
Ref: TM-T15464
| 1mg | 37.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 359.00 € | ||
| 200mg | 511.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
IU1-47
CAS:670270-31-2
IU1-47 is an effective and specific USP14 inhibitor (IC50: 0.6 μM). IU1-47 causes tau elimination …
Formula:
C19H23ClN2O
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
330.85
Ref: TM-T15604
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 775.00 € | ||
| 500mg | 1,566.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MF-094
CAS:2241025-68-1
MF-094 is a selective USP30 inhibitor with IC50 of 0.12 μM. MF-094 can increase protein …
Formula:
C30H37N3O4S
Purity:
98.46%
Color and Shape:
Solid
Molecular weight:
535.7
Ref: TM-T12024
| 1mg | 42.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 277.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 642.00 € | ||
| 500mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
C527
CAS:192718-06-2
C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for …
Formula:
C17H8FNO3
Purity:
97.22%
Color and Shape:
Solid
Molecular weight:
293.25
Ref: TM-T14852
| 5mg | 34.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 135.00 € | ||
| 100mg | 208.00 € | ||
| 200mg | 305.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Wu-5
CAS:2630378-05-9
Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown …
Formula:
C15H13NO7S
Purity:
99.29%
Color and Shape:
Soild
Molecular weight:
351.33
Ref: TM-T77763
| 1mg | 82.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 584.00 € | ||
| 50mg | 926.00 € | ||
| 100mg | 1,234.00 € | ||
| 500mg | 2,496.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
OTUB1/USP8-IN-1 HCl
OTUB1/USP8-IN-1 HCL is a potent dual inhibitor of OTUB1 and USP8 with potential antitumour activity, …
Formula:
C22H17Cl2FN2O4
Purity:
99.90%
Color and Shape:
Liquid
Molecular weight:
463.29
Ref: TM-T72784L
| 1mg | 159.00 € | ||
| 5mg | 337.00 € | ||
| 10mg | 405.00 € | ||
| 25mg | 932.00 € | ||
| 50mg | 1,435.00 € | ||
| 100mg | 1,869.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
USP8-IN-2
CAS:2477651-11-7
USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 …
Formula:
C19H20ClF3N4OS
Purity:
98.83%
Color and Shape:
Liquid
Molecular weight:
444.9
Ref: TM-T67876
| 1mg | 95.00 € | ||
| 5mg | 203.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 753.00 € | ||
| 100mg | 997.00 € | ||
| 1mL*10mM (DMSO) | 236.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
USP8-IN-3
CAS:2477651-10-6
USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of …
Formula:
C18H18F3N5O2S
Purity:
99.18%
Color and Shape:
Liquid
Molecular weight:
425.43
Ref: TM-T67873
| 1mg | 35.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 464.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
OTUB2-IN-1
OTUB2-IN-1 is an OTUB2 inhibitor with antitumor activity and can be used to study skin …
Formula:
C19H18N2O6S2
Color and Shape:
Liquid
Molecular weight:
434.49
Ref: TM-T87947
| 1mg | 178.00 € | ||
| 5mg | 441.00 € | ||
| 10mg | 631.00 € | ||
| 25mg | 985.00 € | ||
| 50mg | 1,359.00 € | ||
| 100mg | 1,796.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Vialinin A
CAS:858134-23-3
Vialinin A, a p-terphenyl with antioxidant properties, inhibits TNF-α/USP4/5/SENP1, used in autoimmune/cancer research.
Formula:
C34H26O8
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
562.57
Ref: TM-T22168
| 1mg | 199.00 € | ||
| 5mg | 405.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 919.00 € | ||
| 50mg | 1,275.00 € | ||
| 100mg | 1,657.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
STD1T
CAS:893075-58-6
STD1T is a USP2a inhibitor with anticancer activity that reduces levels of the cell cycle …
Formula:
C19H19N3O4S2
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
417.5
Ref: TM-T36970
| 1mg | 214.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
USP1-IN-2
CAS:2098212-05-4
USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.
Formula:
C26H22F4N6O
Purity:
99.60% - 99.88%
Color and Shape:
Liquid
Molecular weight:
510.486
Ref: TM-T63518
| 1mg | 276.00 € | ||
| 5mg | 679.00 € | ||
| 10mg | 868.00 € | ||
| 25mg | 1,320.00 € | ||
| 50mg | 1,712.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
USP8-IN-1
CAS:2477650-96-5
USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits …
Formula:
C18H21N5O3S
Purity:
98.01%
Color and Shape:
Soild
Molecular weight:
387.46
Ref: TM-T60146
| 1mg | 86.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 445.00 € | ||
| 50mg | 628.00 € | ||
| 100mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 198.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VLX1570
CAS:1431280-51-1
VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM …
Formula:
C23H17F2N3O6
Purity:
98.53% - 99.91%
Color and Shape:
Solid
Molecular weight:
469.39
Ref: TM-T4067
| 1mg | 94.00 € | ||
| 2mg | 151.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 398.00 € | ||
| 25mg | 668.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,277.00 € | ||
| 1mL*10mM (DMSO) | 264.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML-323
CAS:1572414-83-5
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal …
Formula:
C23H24N6
Purity:
99.87% - 99.96%
Color and Shape:
Solid
Molecular weight:
384.48
Ref: TM-T1757
| 5mg | 197.00 € | ||
| 10mg | 315.00 € | ||
| 25mg | 487.00 € | ||
| 50mg | 737.00 € | ||
| 100mg | 1,083.00 € | ||
| 1mL*10mM (DMSO) | 233.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GNE-6640
CAS:2009273-67-8
GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 …
Formula:
C20H18N4O
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
330.38
Ref: TM-T5461
| 1mg | 70.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 762.00 € | ||
| 100mg | 1,060.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
XL177A
CAS:2417089-74-6
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing …
Formula:
C48H57ClN8O5
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
861.47
Ref: TM-T9122
| 1mg | 94.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 292.00 € | ||
| 25mg | 495.00 € | ||
| 50mg | 714.00 € | ||
| 100mg | 1,006.00 € | ||
| 1mL*10mM (DMSO) | 281.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
USP7-IN-8
CAS:2009273-60-1
Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 …
Formula:
C21H21N3O2
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
347.41
Ref: TM-T9217
| 1mg | 46.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 543.00 € | ||
| 200mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SJB2-043
CAS:63388-44-3
SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).
Formula:
C17H9NO3
Purity:
98.44%
Color and Shape:
Solid
Molecular weight:
275.26
Ref: TM-T7678
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 423.00 € | ||
| 200mg | 611.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DUB-IN-2
CAS:924296-19-5
Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.
Formula:
C15H9N5O
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
275.26
Ref: TM-T11111
| 1mg | 135.00 € | ||
| 2mg | 183.00 € | ||
| 5mg | 280.00 € | ||
| 10mg | 403.00 € | ||
| 25mg | 653.00 € | ||
| 50mg | 926.00 € | ||
| 100mg | 1,276.00 € | ||
| 1mL*10mM (DMSO) | 290.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
