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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • Garenoxacin mesylate hydrate

    CAS:
    <p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>
    Formula:C23H20F2N2O4·CH4O3S·H2O
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:540.53
  • NSC 617145

    CAS:
    <p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>
    Formula:C13H10Cl4N2O4
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:400.04
  • Gemcitabine hydrochloride

    CAS:
    <p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>
    Formula:C9H11F2N3O4·HCl
    Purity:99.28% - 99.98%
    Color and Shape:White Crystalline Granular Odorless
    Molecular weight:299.66
  • Isoindigotin

    CAS:
    <p>Isoindigotin is used in the therapy of Y.</p>
    Formula:C16H10N2O2
    Purity:98.14% - ≥95%
    Color and Shape:Solid
    Molecular weight:262.26
  • Pyridostatin Trihydrochloride

    CAS:
    <p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>
    Formula:C31H35Cl3N8O5
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:706.02
  • Quinizarin

    CAS:
    <p>Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product</p>
    Formula:C14H8O4
    Purity:95.02%
    Color and Shape:Leaves Yellow Red And Needles Dark Red Solid Leaves Or Needles
    Molecular weight:240.21
  • O6-Benzylguanine

    CAS:
    <p>O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.</p>
    Formula:C12H11N5O
    Purity:98.9%
    Color and Shape:Solid Crystalline
    Molecular weight:241.25
  • Deoxycytidine triphosphate

    CAS:
    <p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>
    Formula:C9H16N3O13P3
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:467.16
  • GS-441524

    CAS:
    <p>GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.</p>
    Formula:C12H13N5O4
    Purity:98.78% - 99.75%
    Color and Shape:Solid
    Molecular weight:291.26
  • Methotrexate disodium

    CAS:
    <p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>
    Formula:C20H20N8Na2O5
    Purity:99.77% - 99.96%
    Color and Shape:Solid
    Molecular weight:498.4
  • Pyridostatin TFA

    CAS:
    <p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>
    Formula:C37H35F9N8O11
    Purity:97.09% - 99.84%
    Color and Shape:Solid
    Molecular weight:938.71
  • L189

    CAS:
    <p>L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).</p>
    Formula:C11H10N4OS
    Purity:97.37%
    Color and Shape:Solid
    Molecular weight:246.29
  • TH588

    CAS:
    <p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>
    Formula:C13H12Cl2N4
    Purity:96.05% - 99.82%
    Color and Shape:Solid
    Molecular weight:295.17
  • PfDHODH-IN-1

    CAS:
    <p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>
    Formula:C14H11F3N2O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:296.24
  • NSAH

    CAS:
    <p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>
    Formula:C18H14N2O3
    Purity:99.27%
    Color and Shape:Solid
    Molecular weight:306.32
  • Triciribine

    CAS:
    <p>Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.</p>
    Formula:C13H16N6O4
    Purity:99.01% - 99.87%
    Color and Shape:Solid
    Molecular weight:320.3
  • Levofloxacin hydrochloride

    CAS:
    <p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>
    Formula:C18H21ClFN3O4
    Purity:99.78% - 99.98%
    Color and Shape:Solid
    Molecular weight:397.8
  • CeMMEC13

    CAS:
    <p>CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).</p>
    Formula:C19H16N2O4
    Purity:98.52%
    Color and Shape:Solid
    Molecular weight:336.34
  • SCR130

    CAS:
    <p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂,可诱导细胞凋亡并,具有抗癌活性。 它特异性依赖连接酶 IV,抑制 DNA 的末端连接。</p>
    Formula:C19H13Cl2N3O2S
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:418.3
  • 360A

    CAS:
    <p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>
    Formula:C27H23N5O2
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:449.5
  • PCNA-I1

    CAS:
    <p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>
    Formula:C17H14N2O2S
    Purity:97.64%
    Color and Shape:Solid
    Molecular weight:310.37
  • 6-AZATHYMINE

    CAS:
    <p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>
    Formula:C4H5N3O2
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:127.1
  • RI-2

    CAS:
    <p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>
    Formula:C21H18Cl2N2O4
    Purity:99.63% - 99.86%
    Color and Shape:Solid
    Molecular weight:433.28
  • AT-130

    CAS:
    <p>AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.</p>
    Formula:C22H22BrN3O5
    Purity:97.81%
    Color and Shape:Solid
    Molecular weight:488.33
  • CRT0044876

    CAS:
    <p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>
    Formula:C9H6N2O4
    Purity:98.27% - 98.98%
    Color and Shape:Brown Powder
    Molecular weight:206.15
  • Ro5-3335

    CAS:
    <p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>
    Formula:C13H10ClN3O
    Purity:99.42% - 99.87%
    Color and Shape:Solid
    Molecular weight:259.69
  • Favipiravir

    CAS:
    <p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>
    Formula:C5H4FN3O2
    Purity:97.32% - 99.90%
    Color and Shape:Solid
    Molecular weight:157.1
  • Quarfloxin

    CAS:
    <p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>
    Formula:C35H33FN6O3
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:604.67
  • Madrasin

    CAS:
    <p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>
    Formula:C16H17N5O2
    Purity:99.06% - 99.61%
    Color and Shape:Solid
    Molecular weight:311.34
  • Nimustine Hydrochloride

    CAS:
    <p>Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.</p>
    Formula:C9H14Cl2N6O2
    Purity:98.80%
    Color and Shape:Solid
    Molecular weight:309.15
  • Cidofovir

    CAS:
    <p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>
    Formula:C8H14N3O6P
    Purity:99.24% - 99.76%
    Color and Shape:Fluffy White Powder
    Molecular weight:279.19
  • RAD51-IN-1

    CAS:
    <p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>
    Formula:C22H16ClN3O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:373.83
  • 3-Hydroxy-2-methylpyridine

    CAS:
    <p>3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.</p>
    Formula:C6H7NO
    Purity:98.96% - 99.03%
    Color and Shape:Beige-Brown Powder
    Molecular weight:109.13
  • NITD-2

    CAS:
    <p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>
    Formula:C23H19N3O4S
    Purity:98.03% - 99.46%
    Color and Shape:Solid
    Molecular weight:433.48
  • CBFβ Inhibitor

    CAS:
    <p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>
    Formula:C12H14N2OS
    Purity:96.50%
    Color and Shape:Solid
    Molecular weight:234.32
  • CX-5461

    CAS:
    <p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C27H27N7O2S
    Purity:95.44% - 99.25%
    Color and Shape:Solid
    Molecular weight:513.61
  • BVDV-IN-1

    CAS:
    <p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>
    Formula:C20H22N4O
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:334.41
  • Danofloxacin

    CAS:
    <p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>
    Formula:C19H20FN3O3
    Purity:99.77% - 99.8%
    Color and Shape:Solid
    Molecular weight:357.38
  • Cynaroside

    CAS:
    <p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>
    Formula:C21H20O11
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:448.38
  • Levofloxacin

    CAS:
    <p>Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.</p>
    Formula:C18H20FN3O4
    Purity:98.14% - 99.80%
    Color and Shape:Off-White To Yellow Crystals
    Molecular weight:361.37
  • Zoliflodacin

    CAS:
    <p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>
    Formula:C22H22FN5O7
    Purity:99.82% - 99.93%
    Color and Shape:Solid
    Molecular weight:487.44
  • Tubercidin

    CAS:
    <p>Tubercidin, an adenosine analogue nucleoside antibiotic, hinders DNA/RNA synthesis and possesses antifungal and antiviral properties.</p>
    Formula:C11H14N4O4
    Purity:98.66% - >99.99%
    Color and Shape:Solid
    Molecular weight:266.25
  • Branaplam

    CAS:
    <p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>
    Formula:C22H27N5O2
    Purity:98.28% - 99.72%
    Color and Shape:Solid
    Molecular weight:393.48
  • 5-Methylcytosine

    CAS:
    <p>5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.</p>
    Formula:C5H7N3O
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:125.13
  • N-Nitrosodiethylamine

    CAS:
    <p>N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine.</p>
    Formula:C4H10N2O
    Purity:99.26% - 99.88%
    Color and Shape:Solid
    Molecular weight:102.14
  • Bractoppin

    CAS:
    <p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>
    Formula:C25H23FN4O
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:414.47
  • ML264

    CAS:
    <p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>
    Formula:C17H21ClN2O4S
    Purity:99.33% - 99.45%
    Color and Shape:Solid
    Molecular weight:384.88
  • Didox

    CAS:
    <p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>
    Formula:C7H7NO4
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:169.13
  • (S)-crizotinib

    CAS:
    <p>(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>
    Formula:C21H22Cl2FN5O
    Purity:98.52% - 99.47%
    Color and Shape:Solid
    Molecular weight:450.34
  • COH29

    CAS:
    <p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>
    Formula:C22H16N2O5S
    Purity:97.04% - 98.92%
    Color and Shape:Solid
    Molecular weight:420.44
  • Tempo

    CAS:
    <p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>
    Formula:C9H18NO
    Purity:98.35%
    Color and Shape:Orange Crystals Or Powder
    Molecular weight:156.25
  • Fialuridine

    CAS:
    <p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>
    Formula:C9H10FIN2O5
    Purity:99.71% - 99.88%
    Color and Shape:Less Crystals Colourless Crystals
    Molecular weight:372.09
  • TH287 hydrochloride

    CAS:
    <p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>
    Formula:C11H11Cl3N4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:305.59
  • Neobavaisoflavone

    CAS:
    <p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>
    Formula:C20H18O4
    Purity:99.31% - 99.87%
    Color and Shape:Solid
    Molecular weight:322.35
  • 5-Bromouridine

    CAS:
    <p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>
    Formula:C9H11BrN2O6
    Purity:99.89%
    Color and Shape:White Powder
    Molecular weight:323.1
  • PolQi2

    CAS:
    <p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>
    Formula:C21H16ClN5O3S
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:453.9
  • 2'-O-(2-Methoxyethyl)adenosine

    CAS:
    <p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.</p>
    Formula:C13H19N5O5
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:325.32
  • VVD-214

    CAS:
    <p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>
    Formula:C20H21F2N3O4S
    Purity:99.24%
    Color and Shape:Soild
    Molecular weight:437.46
  • Metribuzin

    CAS:
    <p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>
    Formula:C8H14N4OS
    Purity:99.07%
    Color and Shape:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)
    Molecular weight:214.29
  • Locked nucleic acid 1

    CAS:
    <p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>
    Formula:C32H32N2O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:572.61
  • GSK4418959

    CAS:
    <p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>
    Formula:C31H30F4N4O5S
    Purity:99.141%
    Color and Shape:Soild
    Molecular weight:646.65
  • DHX9-IN-8

    CAS:
    <p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>
    Formula:C18H16N2O3S2
    Color and Shape:Solid
    Molecular weight:372.46
  • 2'-Azido-2'-deoxyuridine

    CAS:
    <p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>
    Formula:C9H11N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:269.21
  • RI(dl)-2 TFA

    CAS:
    RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.
    Formula:C19H17N3
    Color and Shape:Solid
    Molecular weight:287.36
  • E-982

    CAS:
    <p>E-982 is derived from the reference compound.</p>
    Formula:C25H31NO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:473.58
  • Halofuginone

    CAS:
    <p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>
    Formula:C16H17BrClN3O3
    Purity:99.53%
    Color and Shape:Off-White Solid
    Molecular weight:414.68
  • E3330

    CAS:
    <p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>
    Formula:C21H30O6
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:378.46
  • 3,4-Dihydroxybenzylamine hydrobromide

    CAS:
    <p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>
    Formula:C7H10BrNO2
    Purity:98.49%
    Color and Shape:Light Beige Crystalline Powder
    Molecular weight:220.06
  • Picoplatin

    CAS:
    <p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>
    Formula:C6H10Cl2N2Pt
    Purity:98%
    Color and Shape:Solid
    Molecular weight:376.14
  • HHL-6

    CAS:
    <p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>
    Formula:C19H26N2O3
    Color and Shape:Solid
    Molecular weight:330.42
  • DHX9-IN-1

    CAS:
    <p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>
    Formula:C21H21F2N5O3S
    Color and Shape:Solid
    Molecular weight:461.49
  • Crisnatol

    CAS:
    <p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>
    Formula:C23H23NO2
    Color and Shape:Solid
    Molecular weight:345.43
  • BzDANP

    CAS:
    <p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>
    Formula:C18H24N6
    Color and Shape:Solid
    Molecular weight:324.42
  • SPC-839

    CAS:
    <p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>
    Formula:C18H14N4O3S
    Color and Shape:Solid
    Molecular weight:366.39
  • SEC inhibitor KL-2

    CAS:
    <p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>
    Formula:C17H13ClFNO3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:333.74
  • MTH1-IN-2

    CAS:
    <p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>
    Formula:C24H27N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.55
  • AM-TS23

    CAS:
    <p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>
    Formula:C17H12N2O3S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:388.48
  • ML366

    CAS:
    <p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>
    Formula:C17H19N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:329.35
  • Meturedepa

    CAS:
    <p>Meturedepa is an antineoplastic agent.</p>
    Formula:C11H22N3O3P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:275.28
  • 8-Azido-ADP disodium

    CAS:
    <p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>
    Formula:C10H13N8NaO10P2
    Color and Shape:Solid
    Molecular weight:490.197
  • S-(N-PhenethylthiocarbaMoyl)-L-cysteine

    CAS:
    <p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>
    Formula:C12H16N2O2S2
    Color and Shape:Solid
    Molecular weight:284.4
  • DENV-IN-4

    CAS:
    <p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50&gt;100 μM), and strong selectivity (SI&gt;20.9); suppresses DENV2 and RdRp.</p>
    Formula:C28H32N4O4Si
    Color and Shape:Solid
    Molecular weight:516.66
  • CTP Synthetase-IN-1

    CAS:
    <p>CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.</p>
    Formula:C20H19F3N6O3S2
    Purity:98.11% - 99.18%
    Color and Shape:Solid
    Molecular weight:512.53
  • Direct Black 38 free acid

    CAS:
    <p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>
    Formula:C34H27N9O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:737.77
  • 2-Keto-D-galactose

    CAS:
    <p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>
    Formula:C6H10O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:178.14
  • Codon readthrough inducer 1

    CAS:
    <p>Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.</p>
    Formula:C15H11N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:313.26
  • MS0017509

    CAS:
    <p>MS0017509 is a DNA damage repair inhibitor.</p>
    Formula:C11H10N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:198.22
  • JNJ-9676

    CAS:
    <p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>
    Formula:C28H21F2N5O2
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:497.5
  • TDRL-X80

    CAS:
    <p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>
    Formula:C23H15ClN2O6
    Color and Shape:Solid
    Molecular weight:450.83
  • 3'-Deoxyuridine-5'-triphosphate

    CAS:
    <p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I &amp; II, with a Ki of 2.0 µM.</p>
    Formula:C9H15N2O14P3
    Color and Shape:Solid
    Molecular weight:468.14
  • Beaucage reagent

    CAS:
    <p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>
    Formula:C7H4O3S2
    Purity:98.50%
    Color and Shape:White To Off-White Powder
    Molecular weight:200.23
  • ST7612AA1

    CAS:
    <p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>
    Formula:C20H27N3O4S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:405.51
  • MLAF50

    CAS:
    <p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>
    Formula:C15H12I2O4
    Color and Shape:Solid
    Molecular weight:510.06
  • JFN05510

    CAS:
    <p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>
    Formula:C50H68N7O9PSi
    Color and Shape:Solid
    Molecular weight:970.18
  • Zelpolib

    CAS:
    <p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>
    Formula:C22H21N3O5S2
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:471.55
  • Homocarbonyltopsentin

    CAS:
    <p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>
    Formula:C21H14N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:370.36
  • Triaziquone

    CAS:
    <p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>
    Formula:C12H13N3O2
    Color and Shape:Solid
    Molecular weight:231.25
  • Phelorphan

    CAS:
    <p>Phelorphan is an inhibitor of enkephalinase.</p>
    Formula:C20H22N2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.46
  • HBV-IN-4

    CAS:
    <p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>
    Formula:C24H19ClFN5O3
    Color and Shape:Solid
    Molecular weight:479.89
  • Thiarabine

    CAS:
    <p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>
    Formula:C9H13N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:259.28
  • BMH-22

    CAS:
    <p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Formula:C16H17N3
    Color and Shape:Solid
    Molecular weight:251.33
  • Phen-DC3

    CAS:
    <p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>
    Formula:C34H26N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:550.61
  • Apricitabine

    CAS:
    <p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>
    Formula:C8H11N3O3S
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:229.26
  • Werner syndrome RecQ helicase-IN-4

    CAS:
    <p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>
    Formula:C32H33F3N8O5
    Purity:98.27%
    Color and Shape:Solid
    Molecular weight:666.65
  • DDD100097

    CAS:
    <p>DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.</p>
    Formula:C22H30Cl2F2N4O2S
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:523.47
  • CM03

    CAS:
    <p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>
    Formula:C34H44N6O6
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:632.75
  • AS-136A

    CAS:
    <p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>
    Formula:C17H19F3N4O3S
    Purity:98.52%
    Color and Shape:Solid
    Molecular weight:416.42
  • Nitracrine

    CAS:
    <p>Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.</p>
    Formula:C18H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38
  • Laromustine

    CAS:
    <p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>
    Formula:C6H14ClN3O5S2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:307.78
  • 10-Formyl-5,8-dideazafolic acid

    CAS:
    <p>10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.</p>
    Formula:C22H21N5O7
    Purity:96.04%
    Color and Shape:Solid
    Molecular weight:467.43
  • CID 5951923

    CAS:
    <p>CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.</p>
    Formula:C16H18N2O7S
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:382.39
  • CGP 53353

    CAS:
    <p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>
    Formula:C20H13F2N3O2
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:365.33
  • Synucleozid

    CAS:
    <p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>
    Formula:C22H20N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.43
  • Glucocorticoid receptor modulator 1

    CAS:
    <p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>
    Formula:C24H23ClN2O4S
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:470.97
  • Bofumustine

    CAS:
    <p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>
    Formula:C18H21ClN4O9
    Color and Shape:Solid
    Molecular weight:472.83
  • BMVC

    CAS:
    <p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>
    Formula:C28H25I2N3
    Color and Shape:Solid
    Molecular weight:657.33
  • Werner syndrome RecQ helicase-IN-3

    CAS:
    <p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>
    Formula:C31H30ClF3N8O5
    Color and Shape:Solid
    Molecular weight:687.07
  • Crisnatol mesylate

    CAS:
    <p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>
    Formula:C24H27NO5S
    Color and Shape:Solid
    Molecular weight:441.54
  • 2-Fluoroadenine

    CAS:
    <p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>
    Formula:C5H4FN5
    Purity:98.84% - 99.62%
    Color and Shape:White To Light Yellow Crystal Powder
    Molecular weight:153.12
  • D-Xylofuranose, 1,2,3,5-tetraacetate

    CAS:
    <p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>
    Formula:C13H18O9
    Color and Shape:Solid
    Molecular weight:318.28
  • HBV-IN-16

    CAS:
    <p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>
    Formula:C22H20ClNO4
    Color and Shape:Solid
    Molecular weight:397.85
  • GW8510

    CAS:
    <p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>
    Formula:C21H15N5O3S2
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:449.51
  • REV7/REV3L-IN-1

    CAS:
    <p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>
    Formula:C19H21N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:371.45
  • AB-182

    CAS:
    <p>AB-182 is an aziridine derivative with antitumor activity.</p>
    Formula:C11H22N3O4P
    Color and Shape:Solid
    Molecular weight:291.28
  • BPIC

    CAS:
    <p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>
    Formula:C27H20N2O5
    Color and Shape:Solid
    Molecular weight:452.46
  • HBV-IN-22

    CAS:
    <p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>
    Formula:C26H29N3O2S2
    Color and Shape:Solid
    Molecular weight:479.66
  • Braco-19 trihydrochloride

    CAS:
    <p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>
    Formula:C35H46Cl3N7O2
    Purity:98.74%
    Color and Shape:Solid
    Molecular weight:703.14
  • UIAA-II-232

    CAS:
    <p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>
    Formula:C20H24FN5O3
    Color and Shape:Solid
    Molecular weight:401.43
  • Datelliptium chloride

    CAS:
    <p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>
    Formula:C23H28ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.94
  • RHI002-Me

    CAS:
    <p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>
    Formula:C18H19N3O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.49
  • Antitumor agent-84


    <p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>
    Formula:C24H31N7
    Color and Shape:Solid
    Molecular weight:417.55
  • HIV-1 inhibitor-43

    CAS:
    <p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), &lt;0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>
    Formula:C24H21ClN2O4S
    Color and Shape:Solid
    Molecular weight:468.95
  • HIPP

    CAS:
    <p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>
    Formula:C9H9NO3
    Color and Shape:Solid
    Molecular weight:179.17
  • IDD388

    CAS:
    <p>IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.</p>
    Formula:C16H12BrClFNO4
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:416.63
  • Cylindrospermopsin

    CAS:
    <p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>
    Formula:C15H21N5O7S
    Color and Shape:Solid
    Molecular weight:415.42
  • EGFR/HER2/TS-IN-2

    CAS:
    <p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 &amp; TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>
    Formula:C26H21N7OS2
    Color and Shape:Solid
    Molecular weight:511.62
  • FLDP-5

    CAS:
    <p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>
    Formula:C21H21NO5
    Color and Shape:Solid
    Molecular weight:367.4
  • BAY-707

    CAS:
    <p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>
    Formula:C15H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:288.34
  • 15(S)-HpETE

    CAS:
    <p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>
    Formula:C20H32O4
    Color and Shape:Solid
    Molecular weight:336.47
  • HBV-IN-21

    CAS:
    <p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>
    Formula:C17H17FN4OS2
    Color and Shape:Solid
    Molecular weight:376.47
  • CAY10760

    CAS:
    <p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>
    Formula:C28H24ClN3O3
    Color and Shape:Solid
    Molecular weight:485.96
  • 360A iodide

    CAS:
    <p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>
    Formula:C27H23I2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:703.31
  • ERCC1-XPF-IN-1

    CAS:
    <p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>
    Formula:C28H32ClN5O2
    Color and Shape:Solid
    Molecular weight:506.04
  • BMH-23

    CAS:
    <p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Formula:C15H15N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:237.3
  • cp028

    CAS:
    <p>cp028 inhibits pre-mRNA splicing in vitro.</p>
    Formula:C23H17FN2O4
    Color and Shape:Solid
    Molecular weight:404.39
  • Halofuginone hydrobromide

    CAS:
    <p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>
    Formula:C16H17BrClN3O3·HBr
    Purity:97.01% - 99.73%
    Color and Shape:Solid
    Molecular weight:495.59
  • Enocitabine

    CAS:
    <p>Enocitabine is a nucleoside analog.</p>
    Formula:C31H55N3O6
    Purity:97.22%
    Color and Shape:Solid
    Molecular weight:565.78
  • IACS-4759

    CAS:
    <p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>
    Formula:C10H17N3O2
    Color and Shape:Solid
    Molecular weight:211.26
  • 5,10-Dideazaaminopterin

    CAS:
    <p>5,10-Dideazaaminopterin is an antileukemic drug.</p>
    Formula:C21H22N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.44
  • HBV-IN-14

    CAS:
    <p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>
    Formula:C22H21ClN2O5
    Color and Shape:Solid
    Molecular weight:428.87
  • MMV688845

    CAS:
    <p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>
    Formula:C24H25N3O3S
    Color and Shape:Solid
    Molecular weight:435.54
  • CB 3717

    CAS:
    <p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>
    Formula:C24H23N5O6
    Color and Shape:Solid
    Molecular weight:477.47
  • NPD9948

    CAS:
    <p>NPD9948 is a competitive inhibitor of MTH1.</p>
    Formula:C13H14N6
    Color and Shape:Solid
    Molecular weight:254.29
  • BMVC2

    CAS:
    <p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>
    Formula:C28H25I2N3
    Color and Shape:Solid
    Molecular weight:657.33
  • Antitumor agent-85


    <p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>
    Formula:C24H33N7
    Color and Shape:Solid
    Molecular weight:419.57
  • CBL 0100 free base

    CAS:
    <p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>
    Formula:C24H26N2O2
    Purity:98.18% - 98.86%
    Color and Shape:Solid
    Molecular weight:374.48
  • Antibacterial agent 124

    CAS:
    <p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>
    Formula:C16H17ClFN3O2
    Color and Shape:Solid
    Molecular weight:337.78
  • NSC666715

    CAS:
    <p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>
    Formula:C15H13Cl2N5O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.33
  • HBV-IN-15

    CAS:
    <p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>
    Formula:C24H23ClO6
    Color and Shape:Solid
    Molecular weight:442.89
  • ML372

    CAS:
    <p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>
    Formula:C18H20N2O4S
    Color and Shape:Solid
    Molecular weight:360.43
  • Fozivudine tidoxil

    CAS:
    <p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>
    Formula:C35H64N5O8PS
    Color and Shape:Solid
    Molecular weight:745.95
  • 6-Hydroxy-DOPA

    CAS:
    <p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>
    Formula:C9H11NO5
    Purity:97.78% - 97.95%
    Color and Shape:Solid
    Molecular weight:213.19
  • Cytembena

    CAS:
    <p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>
    Formula:C11H8BrNaO4
    Purity:99.35%
    Color and Shape:White Powder
    Molecular weight:307.07
  • SMN-C2

    CAS:
    <p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>
    Formula:C24H27N5O2
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:417.5
  • Galocitabine

    CAS:
    <p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>
    Formula:C19H22FN3O8
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:439.39
  • D-I03

    CAS:
    <p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>
    Formula:C23H36N6S
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:428.64
  • CHD1Li 6.11

    CAS:
    <p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>
    Formula:C21H22BrN5OS
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:472.4
  • Talviraline

    CAS:
    <p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>
    Formula:C15H20N2O3S2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:340.46
  • ERCC1-XPF-IN-2

    CAS:
    <p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>
    Formula:C15H13Cl2NO3
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:326.17
  • 116-9e

    CAS:
    <p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>
    Formula:C31H32N2O5
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:512.6
  • TTP-8307

    CAS:
    <p>TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.</p>
    Formula:C27H21FN4O
    Purity:98.95%
    Color and Shape:Solid
    Molecular weight:436.48
  • Caracemide

    CAS:
    <p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>
    Formula:C6H11N3O4
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:189.17
  • ZIM

    CAS:
    <p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>
    Formula:C20H19N3O3
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:349.38
  • RP-6685

    CAS:
    <p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>
    Formula:C22H14F7N5O
    Purity:99.65%
    Color and Shape:Soild
    Molecular weight:497.37
  • Anticancer agent 73

    CAS:
    <p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>
    Formula:C14H15NO4
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:261.27
  • DDRI-18

    CAS:
    <p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>
    Formula:C26H20N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:416.48
  • Galidesivir hydrochloride

    CAS:
    <p>Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.</p>
    Formula:C11H16ClN5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:301.73
  • DNA polymerase-IN-3

    CAS:
    <p>DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in</p>
    Formula:C13H12O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:232.23
  • Votoplam

    CAS:
    <p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>
    Formula:C21H25N9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.48
  • 5,6,7,8-Tetrahydro-8-deazahomofolic acid

    CAS:
    <p>5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>
    Formula:C21H26N6O6
    Color and Shape:Solid
    Molecular weight:458.47
  • 5-DACTHF

    CAS:
    <p>5,11-methenyltetrahydrohomofolate blocks GAR &amp; AIR transformylase; used as an anti-purine drug.</p>
    Formula:C19H24N6O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:432.43
  • Diazoketone methotrexate

    CAS:
    <p>Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.</p>
    Formula:C21H22N10O4
    Color and Shape:Solid
    Molecular weight:478.46
  • WRN inhibitor 3

    CAS:
    <p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>
    Formula:C20H20N2O5S
    Color and Shape:Solid
    Molecular weight:400.45
  • TAS-114

    CAS:
    <p>TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.</p>
    Formula:C21H29N3O6S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:451.54
  • UNC-2170

    CAS:
    <p>UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.</p>
    Formula:C14H21BrN2O
    Purity:97.44%
    Color and Shape:Solid
    Molecular weight:313.23
  • BVDU 5′-Triphosphate

    CAS:
    <p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>
    Formula:C11H16BrN2O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:573.08
  • WRN inhibitor 1

    CAS:
    <p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>
    Formula:C16H13FN2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.35
  • 8-Azahypoxanthine

    CAS:
    <p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>
    Formula:C4H3N5O
    Purity:99.66%
    Color and Shape:Light Yellow To Light Beige Fine Crystalline
    Molecular weight:137.1
  • 9-Deazaguanine

    CAS:
    <p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>
    Formula:C6H6N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:150.14
  • UNC2170 maleate

    CAS:
    <p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>
    Formula:C14H21BrN2OC4H4O4
    Color and Shape:Solid
    Molecular weight:429.31
  • DAM-IN-1

    CAS:
    <p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>
    Formula:C16H17NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:287.31
  • Pencitabine

    CAS:
    <p>Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.</p>
    Formula:C15H20F3N3O6
    Color and Shape:Solid
    Molecular weight:395.33
  • COH1

    CAS:
    <p>COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].</p>
    Formula:C11H10N2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:250.27
  • WRN inhibitor 2

    CAS:
    <p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>
    Formula:C15H11F3N2O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:420.38
  • H3B-968

    CAS:
    <p>H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease</p>
    Formula:C22H18F6N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:548.46
  • AVG-233

    CAS:
    <p>AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.</p>
    Formula:C26H22ClN5O3
    Purity:99%
    Color and Shape:Solid
    Molecular weight:487.94
  • hDHODH-IN-1

    CAS:
    <p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>
    Formula:C17H14N2O2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:278.31
  • RNA polymerase II-IN-1

    CAS:
    <p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>
    Formula:C38H53N11O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:887.96
  • DHX9-IN-6

    CAS:
    <p>DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.</p>
    Formula:C23H18ClFN4O4S2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:533
  • DHX9-IN-4

    CAS:
    <p>DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.</p>
    Formula:C21H22ClN5O4S2
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:508.01