Antibacterial

<p>Ionomycin is a calcium ionophore and a Ca2+ -binding antibiotic, increases intracellular Ca 2 + to induce cellular responses. High-Quality, Low-Cost!</p>

<p>Ceftolozane sulfate (FR-264205) is a cephalosporin antibiotic with broad-spectrum antimicrobial activity used in the study of pneumonia.</p>

<p>2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.</p>

<p>Metronidazole Benzoate, a salt of Metronidazole and benzoic acid, treats anaerobic infections with antibacterial and anti-parasitic properties.</p>

<p>Tribromsalan (3,5,4'-Tribromosalicylanilide) is an inhibitor of Mycobacterium tuberculosis and abscess bacillus.</p>

<p>Cefuroxime (Cephuroxime) is a second-generation cephalosporin antibiotic with antimicrobial activity for the study of soft tissue infections.</p>

<p>Chlorobutanol hemihydrate (Chlorbutol hemihydrate) is an antiseptic with antimicrobial activity, inhibiting Gram-positive and fungi.</p>

<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>

<p>PF-04753299: potent LpxC inhibitor, kills gonococcus, fights E. coli/P. aeruginosa/K. pneumoniae; used in gram-negative bacteria research.</p>

<p>Lansoprazole sulfide (AG-177) is an active metabolite of Lansoprazole .Lansoprazole is a proton pump inhibitor and antitubercular agents M.TB.</p>

<p>BC-7013, a pleuromutilin antibiotic, is ued potentially for the treatment of clostridial infection.</p>

<p>Azoxystrobin (Bankit) is a broad-spectrum fungicide blocking electron transfer, causing ROS, apoptosis, and affecting respiration.</p>

<p>Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.</p>

<p>Stability Air Sensitive<br>Applications Levopimaric Acid is a major component of pine oleoresin. It is an abietane-type of diterpene resin acid and has antibacterial, cardiovascular, and antioxidant properties.<br>References Kersten, P. J., et al.: J. Chem. Ecol., 32(12), 2679-85 (2006)<br></p>

<p>5,6-Dihydroxyindole, a melanin precursor, exhibits wide antibacterial, antiviral, antifungal, and antiparasitic properties, and is cytotoxic to pathogens.</p>

<p>3-Formyl rifamycin is a degradation product of Rifampicin, with antibacterial activity.</p>

<p>Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.</p>

<p>Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells and can be used in the study of gastric ulcers.</p>

<p>Propiconazole (PRO) is an orally active brassinosteroid biosynthesis inhibitor and a triazole fungicide with antifungal activity.</p>

<p>Dermabond (2-Octyl cyanoacrylate) is a tissue adhesive commonly used for wound or surgical incision closure, with antibacterial properties.</p>

<p>Tiamulin fumarate (Thiamutilin fumarate) is an antibiotic with antimicrobial activity that inhibits protein synthesis and is used in the study of pneumocystitis</p>

<p>Golotimod (SCV 07) is an antimicrobial active dipeptide with immunomodulatory activity for the study of recurrent genital herpes simplex virus 2 infections.</p>

<p>Florfenicol amine hydrochloride is a veterinary antibiotic with antimicrobial activity that can be used to study diseases caused by Bartonella henselae.</p>

<p>Cetalkonium chloride, an ammonium preservative with anti-inflammatory properties, aids in aphthous ulcer research.</p>

<p>Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli and may be used to study infectious diseases.</p>

<p>Norfloxacin-d8 is a deuterated compound of Norfloxacin. Norfloxacin has a CAS number of 70458-96-7. Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.</p>

<p>Sulfasalazine-d4 is a deuterated compound of Sulfasalazine. Sulfasalazine has a CAS number of 599-79-1. Sulfasalazine is a synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug</p>

<p>Triclosan methyl-d3 (methoxy-d3) is a deuterated compound of Triclosan methyl. Triclosan methyl has a CAS number of 4640-01-1. Triclosan-methyl is a transformation product of triclosan. Triclosan is a bactericide in personal care products such as toothpaste, shampoos, and soaps. Triclosan is also a stabilizing agent in a multitude of detergents and cosmetics.</p>

<p>Ethambutol-d8 is a deuterated compound of Ethambutol. Ethambutol has a CAS number of 74-55-5. Ethambutol is a bacteriostatic antimycobacterial agent obstructed the formation of cell wall by inhibiting arabinosyl transferases.</p>

<p>Penicillin V-d5 is a deuterated compound of Penicillin V. Penicillin V has a CAS number of 87-08-1.</p>

<p>Amoxicillin D4 (Amoxycillin D4) is a deuterium-labeled Amoxicillin. Amoxicillin is an antibiotic with broad-spectrum antimicrobial activity.</p>

<p>Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.</p>

<p>Oxacillin (Oxabel) is an antibiotic of the penicillin class, which exerts bactericidal effects by inhibiting bacterial cell wall synthesis.</p>

<p>Salinazid (Salicylaldehyde isonicotinoyl hydrazone) is a potent Cu(II) ionophore which preferentially kills HepG2 cells over HUVEC cells, and is superior to</p>

<p>β-Chloro-L-alanine (L-β-Chloroalanine), a bacteriostatic amino acid analog, inhibits a number of enzymes, including threonine deaminase and alanine racemase.</p>

<p>Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.</p>

<p>Gremubamab (MEDI3902) is a bivalent humanised monoclonal antibody, binds to PAPcrV protein and Psl extracellular polysaccharide, Pseudomonas aeruginosa.</p>

<p>Panobacumab (KBPA101) is a human IgM/κ monoclonal antibody targeting P. aeruginosa serotype O11 LPS O polysaccharide.</p>

<p>Tosatoxumab (AR-301; KBSA301) is a fully human immunoglobulin-class monoclonal antibody that targets and neutralises S. aureus α-toxin antibiotic-adjuvant</p>

<p>"Sulfacytine, an oral short-acting sulfonamide antibiotic, treats infections by blocking bacterial folic acid synthesis."</p>

<p>Cefaloridine: first-gen cephalosporin derivative, zwitterionic, treats pneumococcal pneumonia, effective against staph and strep.</p>

<p>Acediasulfone is an antibiotic. It is used to treat ear infections.</p>

<p>NSC 31153 is a bioactive chemical.</p>

<p>Edetate Sodium (Trilon B, Na₄EDTA) is a metal chelating agent that binds to divalent and trivalent metal cations, antibacterial and anticoagulant.</p>

<p>Bezlotoxumab is a monoclonal antibody that binds Clostridium difficile toxin B, preventing epithelial damage, colitis, and infection recurrence.</p>

<p>Obiltoxaximab is a monoclonal antibody targeting the free protective antigen (PA) of Bacillus anthracis, inhalational anthrax</p>

<p>1-O-(4-Hydroxybenzoyl)-glycerol is an antibacterial agent that inhibits the growth of Staphylococcus aureus, Escherichia coli, Saccharomyces cerevisiae, and Fusarium culmorum, achieving a maximum inhibition rate of 70% at 20 mM. It exhibits mild skin irritancy.</p>

<p>NSC 31156 is a bioactive chemical.</p>

<p>the primary metabolite of ceftiofur</p>

<p>6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-, derived from 2,3-Bis(bromomethyl)quinoxaline, displays antibacterial properties.</p>

<p>Azlocillin is a semisynthetic ampicillin-derived penicillin belonging to acylureido.</p>

<p>Proflavine dihydrochloride is a topical antiseptic.</p>

<p>Brobactam is a beta lactamase inhibitor with antibacterial activity.</p>

<p>Saccharin sodium is a type of artificial or nonnutritive sweetener. Saccharin sodium is used in the production of various foods and pharmaceutical products.</p>

<p>Omodenbamab (514-G3) is a humanised monoclonal antibody that neutralises SpA (Staphylococcus Protein A), on the cell wall of S. aureus.</p>

<p>Methicillin: Narrow-spectrum beta-lactam, penicillin-type antibiotic for certain gram-positive bacterial infections.</p>

<p>Dihydrostreptomycin is an antibiotic.</p>

<p>Pagibaximab, a chimeric IgG1, targets lipoteichoic acid to prevent staph sepsis from S. aureus/epidermidis.</p>

<p>Suvratoxumab (MEDI4893) is a long-lasting humanized IgG1κ monoclonal antibody targeting S. aureus α-toxin, enhancing survival in pneumonia.</p>

<p>Tosylchloramide sodium salt is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.</p>

<p>Fibracillin is a penicillin antibiotic.</p>

<p>Demecycline is an antibiotic.</p>

<p>FOL7185 is an inhibitor of IspD and IspE enzymes isolated from bacteria.</p>

<p>Clavulanate potassium,β-Lactamase inhibitor with antibiotic activity.</p>

<p>Benzoxiquine (NSC 3951) is a cosmetic biocide that inhibits oral microbial growth and in vitro plaque formation.</p>

<p>Ethyl parahydroxybenzoate-d4 is a deuterated compound of Ethyl parahydroxybenzoate. Ethyl parahydroxybenzoate has a CAS number of 120-47-8. Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.</p>

<p>Propylparaben-d4 is a deuterated compound of Propylparaben. Propylparaben has a CAS number of 94-13-3. Propylparaben is an antimicrobial agent, preservative, flavouring agent</p>

<p>Cortisol-1,2-d2 is a deuterated compound of Cortisol. Cortisol has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.</p>

<p>Sulfathiazole Sodium is an organosulfur compound. It also has been used as a short-acting sulfa drug.</p>

<p>Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.</p>

<p>Sulisatin, a laxative, becomes BHMI in the large intestine, causing its effect.</p>

<p>Sulfiram is an ectoparasiticide and is a drug applied topically to treat scabies.</p>

<p>Benzoylacetone (AI3 10572) exhibits antibacterial activity.</p>

<p>DprE1-IN-10 (hit 2), an inhibitor of Decaprenylphosphoryl-β-D-ribose-2′-epimerase (DprE1), holds potential for the study of tuberculosis.</p>

<p>Bacampicillin is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.</p>

<p>Dodine: fungicide for scab in apples/pears/pecans, peach brown rot, foliar diseases in strawberries/cherries, and as biocide/preservative.</p>

<p>Stearyldiethanolamine (2,2'-(Octadecylazanediyl)diethanol) can be used in studies about antibacterial nonwoven fabric and antibacterial freshness-keeping film.</p>

<p>Olanexidine gluconate is an antiseptic/disinfectant compound with potent bactericidal activity against Gram-negative and Gram-positive bacteria.</p>

<p>PPM1A-IN-1 (Compound IV-4) is an inhibitor of the PP2C Ser/Thr protein phosphatase Mg2+/Mn2+-dependent 1A. It exhibits antibacterial activity against Mycobacterium tuberculosis.</p>

<p>N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone has antibacterial activity.</p>

<p>C18G, a synthetic α-helical peptide derived from human platelet factor IV, exhibits biological activity with pronounced antibacterial properties against</p>

<p>Cephradine monohydrate is a β-lactam cephalosporin antibiotic exhibiting broad-spectrum activity against Gram-positive and Gram-negative pathogens.</p>

<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>

<p>cis-Nerolidol, a sesquiterpene alcohol present in numerous plants, exhibits antioxidant and antibacterial properties.</p>

<p>Saccharin sodium salt hydrate, a sweetener for foods and diabetic diets, has been probed for carcinogenicity.</p>

<p>Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.</p>

<p>BB2-50F is a potent, multi-targeting bioenergetic bactericidal inhibitor of M. tuberculosis that sterilizes both replicating and non-replicating M. tuberculosis. It inhibits succinate oxidation, decreases the activity of the tricarboxylic acid (TCA) cycle, and results in succinate secretion from M. tuberculosis. [1]</p>

<p>Ceftezole: alpha-glucosidase inhibitor, anti-diabetic, broad-spectrum antibiotic for gram-positive/negative bacteria.</p>

<p>Golotimod TFA (SCV 07 TFA) is a dipeptide exhibiting immunomodulatory and antibacterial activity, alleviates radiation-induced oral mucositis.</p>

<p>Ro 20-0657/000 is a metabolite of Trimethoprim, a dihydrofolate reductase inhibitor used as an antibacterial in medicine.</p>

<p>GWP-042 is an effective inhibitor of Mycobacterium alanine dehydrogenase (Ald) Rv2780, with an IC50 of 0.21 μM. It exhibits antibacterial activity against Mycobacterium tuberculosis (M. tuberculosis) infections in vivo.</p>

<p>Trimosulfa is a combination of trimethoprim and sulfamethoxazole, an antibiotic combination. Sulfamethoxazole inhibits dihydropteroate synthase, while trimethoprim inhibits dihydrofolate reductase (dihydrofolate reductase), making it effective for mild to moderate bacterial infections against many Gram-negative and Gram-positive bacteria.</p>

<p>21272541 is a potent FabI protein inhibitor that significantly reduces infections caused by Gram-negative organisms [1].</p>

<p>Chloramphenicol palmitate is a broad-spectrum antibiotic effective against various bacteria and used for bacterial selection in gene studies.</p>

<p>Lapyrium, a biocide/antistatic cationic surfactant in personal care, also treats waste-water/corrosion as chloride salt.</p>

<p>Applications Protected Kanamycin A (K137500). Antibiotic complex produced by Streptomyces kanamyceticus Okami &amp; Umezawa from Japanese soil. Comprised of three components, kanamycin A, the major component, and kanamycins B and C, two minor congeners. Antibacterial.<br>References Ito, et al.: J. Antibiot., 17, 189 (1964), Toda, S., et al.: J. Antibiot., 30, 1002 (1977), Claes, P.J., et al.: Anal. Profiles Drug. Subs., 6, 259 (1977),<br></p>

<p>Norvancomycin hydrochloride (Desmethyl-vancomycin hydrochloride) is used as a treatment for endocarditis, osteomyelitis, pneumonia, sepsis, or soft tissue</p>

<p>Polyquaternium-1: a mild eye-safe preservative that inhibits microbes in multi-dose ophthalmic meds.</p>