PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
Tideglusib
CAS:865854-05-3
Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory …
Formula:
C19H14N2O2S
Purity:
98.89% - 99.84%
Color and Shape:
Solid
Molecular weight:
334.39
Ref: TM-T3067
| 10mg | 46.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 185.00 € | ||
| 200mg | 279.00 € | ||
| 500mg | 482.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Alpelisib
CAS:1217486-61-7
Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity.
Formula:
C19H22F3N5O2S
Purity:
98% - 99.73%
Color and Shape:
Solid
Molecular weight:
441.47
Ref: TM-T1921
| 1g | 642.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 150.00 € | ||
| 200mg | 261.00 € | ||
| 500mg | 438.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Alflutinib mesylate
CAS:2130958-55-1
Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, …
Formula:
C29H35F3N8O5S
Purity:
97.94% - 99.81%
Color and Shape:
Solid
Molecular weight:
664.7
Ref: TM-T7175
| 1mg | 77.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 388.00 € | ||
| 50mg | 576.00 € | ||
| 100mg | 816.00 € | ||
| 500mg | 1,662.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
7BIO
CAS:916440-85-2
7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:
C16H10BrN3O2
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
356.17
Ref: TM-T22012
| 5mg | 44.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 387.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY2090314
CAS:603288-22-8
LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia …
Formula:
C28H25FN6O3
Purity:
99.03% - 99.88%
Color and Shape:
Solid
Molecular weight:
512.53
Ref: TM-T1755
| 1mg | 48.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 624.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E)-AG 556
CAS:133550-41-1
AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
Formula:
C20H20N2O3
Purity:
99.48%
Color and Shape:
Light Yellow Powder
Molecular weight:
336.38
Ref: TM-T21853
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 146.00 € | ||
| 100mg | 226.00 € | ||
| 200mg | 333.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NSC 228155
CAS:113104-25-9
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and …
Formula:
C11H6N4O4S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
290.25
Ref: TM-T6908
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 484.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Afatinib Dimaleate
CAS:850140-73-7
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR …
Formula:
C32H33ClFN5O11
Purity:
100% - 99.66%
Color and Shape:
Solid
Molecular weight:
718.08
Ref: TM-T1773
| 1g | 460.00 € | ||
| 5mg | 40.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 105.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 184.00 € | ||
| 500mg | 308.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mubritinib
CAS:366017-09-6
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
Formula:
C25H23F3N4O2
Purity:
99.85% - 99.87%
Color and Shape:
Solid
Molecular weight:
468.47
Ref: TM-T6124
| 5mg | 189.00 € | ||
| 10mg | 287.00 € | ||
| 25mg | 544.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 270.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY294002
CAS:154447-36-6
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 …
Formula:
C19H17NO3
Purity:
98% - 99.96%
Color and Shape:
Pale Yellow Solid
Molecular weight:
307.34
Ref: TM-T2008
| 5mg | 39.00 € | ||
| 10mg | 50.00 € | ||
| 50mg | 71.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 121.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG1557
CAS:189290-58-2
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: …
Formula:
C16H14IN3O2
Purity:
98.62% - 99.23%
Color and Shape:
Solid
Molecular weight:
407.21
Ref: TM-T2034
| 10mg | 48.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 182.00 € | ||
| 200mg | 273.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bimiralisib
CAS:1225037-39-7
Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, …
Formula:
C17H20F3N7O2
Purity:
97.58% - 99.88%
Color and Shape:
Solid
Molecular weight:
411.38
Ref: TM-T2265
| 1mg | 35.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
E-4031
CAS:113559-13-0
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by …
Formula:
C21H29Cl2N3O3S
Purity:
97.71% - 99.31%
Color and Shape:
Solid
Molecular weight:
474.44
Ref: TM-T7198
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 570.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin AG 528
CAS:133550-49-9
Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 …
Formula:
C18H14N2O3
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
306.32
Ref: TM-T4528
| 5mg | 51.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 408.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sapanisertib
CAS:1224844-38-5
Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.
Formula:
C15H15N7O
Purity:
100% - 99.34%
Color and Shape:
Solid
Molecular weight:
309.33
Ref: TM-T1838
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 344.00 € | ||
| 500mg | 824.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin A9
CAS:10537-47-0
Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed …
Formula:
C18H22N2O
Purity:
98.21% - 99.36%
Color and Shape:
Yellow Solid
Molecular weight:
282.38
Ref: TM-T2479
| 25mg | 54.00 € | ||
| 50mg | 63.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 169.00 € | ||
| 500mg | 374.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
4-Chloro-2'-bromoacetophenone
CAS:536-38-9
4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).
Formula:
C8H6BrClO
Purity:
99.56%
Color and Shape:
White To Beige Solid
Molecular weight:
233.49
Ref: TM-T8908
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 164.00 € | ||
| 200mg | 238.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PP 3
CAS:5334-30-5
PP 3 is a Negative control for the Src kinase inhibitor PP 2
Formula:
C11H9N5
Purity:
98.92%
Color and Shape:
Whit To Off-White Solid
Molecular weight:
211.22
Ref: TM-T23176
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 302.00 € | ||
| 500mg | 719.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
YKL-06-061
CAS:2172617-15-9
YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 …
Formula:
C30H37N7O2
Purity:
99.52% - 99.79%
Color and Shape:
Solid
Molecular weight:
527.66
Ref: TM-T5576
| 1mg | 35.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 573.00 € | ||
| 500mg | 1,226.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GS87
CAS:919936-70-2
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive …
Formula:
C16H11N5O2S
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
337.36
Ref: TM-T8605
| 1mg | 130.00 € | ||
| 2mg | 185.00 € | ||
| 5mg | 279.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 701.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,332.00 € | ||
| 1mL*10mM (DMSO) | 294.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
