PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
NU 7026
CAS:154447-35-5
NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free …
Formula:
C17H15NO3
Purity:
100% - 100%
Color and Shape:
Solid
Molecular weight:
281.31
Ref: TM-T2433
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 444.00 € | ||
| 200mg | 624.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RG13022
CAS:136831-48-6
RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF …
Formula:
C16H14N2O2
Purity:
98.38%
Color and Shape:
Solid
Molecular weight:
266.29
Ref: TM-T3545
| 2mg | 46.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 470.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KY19382
CAS:2226664-93-1
KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may …
Formula:
C17H11Cl2N3O2
Purity:
98.06%
Color and Shape:
Solid
Molecular weight:
360.19
Ref: TM-T9025
| 1mg | 100.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 597.00 € | ||
| 50mg | 849.00 € | ||
| 100mg | 1,142.00 € | ||
| 200mg | 895.00 € | ||
| 500mg | 2,256.00 € | ||
| 1mL*10mM (DMSO) | 245.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WS3
CAS:1421227-52-2
WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase …
Formula:
C28H30F3N7O3
Purity:
97.93% - 98.81%
Color and Shape:
Solid
Molecular weight:
569.58
Ref: TM-T2055
| 5mg | 52.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 386.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CL-387785
CAS:194423-06-8
CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.
Formula:
C18H13BrN4O
Purity:
96.68% - 98.09%
Color and Shape:
Solid
Molecular weight:
381.23
Ref: TM-T2245
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 163.00 € | ||
| 100mg | 255.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Selective PI3Kδ Inhibitor 1
CAS:2088525-31-7
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).
Formula:
C23H20FN7O
Purity:
97.96%
Color and Shape:
Solid
Molecular weight:
429.45
Ref: TM-T5831
| 1mg | 57.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 363.00 € | ||
| 50mg | 495.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 911.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(S)-Sunvozertinib
CAS:2370013-49-1
(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
Formula:
C29H35ClFN7O3
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
584.08
Ref: TM-T9304
| 1mg | 62.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 415.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 878.00 € | ||
| 1mL*10mM (DMSO) | 169.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BI-4020
CAS:2664214-60-0
BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.
Formula:
C30H38N8O2
Purity:
100.00% - 98.44%
Color and Shape:
Solid
Molecular weight:
542.68
Ref: TM-T10534
| 1mg | 164.00 € | ||
| 5mg | 383.00 € | ||
| 10mg | 547.00 € | ||
| 25mg | 817.00 € | ||
| 50mg | 1,089.00 € | ||
| 100mg | 1,455.00 € | ||
| 200mg | 1,985.00 € | ||
| 1mL*10mM (DMSO) | 455.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD 6482
CAS:1173900-33-8
AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 …
Formula:
C22H24N4O4
Purity:
99.79% - 99.95%
Color and Shape:
Solid
Molecular weight:
408.45
Ref: TM-T6087
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 509.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IM-12
CAS:1129669-05-1
IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
Formula:
C22H20FN3O2
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
377.41
Ref: TM-T2261
| 5mg | 53.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 282.00 € | ||
| 100mg | 468.00 € | ||
| 200mg | 391.00 € | ||
| 500mg | 1,016.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG-1557 hydrochloride (189290-58-2(free base))
AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: …
Formula:
C16H15ClIN3O2
Purity:
98.95%
Color and Shape:
Solid
Molecular weight:
443.66
Ref: TM-T4694
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 260.00 € | ||
| 200mg | 381.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Autogramin-1
CAS:2375541-73-2
Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.
Formula:
C23H27N5O5S
Purity:
97.22% - 98.76%
Color and Shape:
Solid
Molecular weight:
485.56
Ref: TM-T10413
| 1mg | 134.00 € | ||
| 5mg | 327.00 € | ||
| 10mg | 458.00 € | ||
| 25mg | 713.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,291.00 € | ||
| 500mg | 2,590.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GNE-317
CAS:1394076-92-6
GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).
Formula:
C19H22N6O3S
Purity:
99.08% - 99.42%
Color and Shape:
Solid
Molecular weight:
414.48
Ref: TM-T6845
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 342.00 € | ||
| 100mg | 426.00 € | ||
| 200mg | 623.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin B44, (+) enantiomer
CAS:133550-37-5
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with …
Formula:
C18H16N2O3
Purity:
97.18%
Color and Shape:
Solid
Molecular weight:
308.33
Ref: TM-T22450
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 266.00 € | ||
| 50mg | 364.00 € | ||
| 100mg | 524.00 € | ||
| 200mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PIK-75 hydrochloride
CAS:372196-77-5
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits …
Formula:
C16H14BrN5O4S·HCl
Purity:
97.82%
Color and Shape:
Solid
Molecular weight:
488.74
Ref: TM-T2287
| 5mg | 42.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 171.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CHIR-99021
CAS:252917-06-9
View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.
Formula:
C22H18Cl2N8
Purity:
97.94% - ≥95%
Color and Shape:
Solid
Molecular weight:
465.34
Ref: TM-T2310
| 2mg | 48.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 409.00 € | ||
| 200mg | 608.00 € | ||
| 500mg | 941.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Compound 401
CAS:168425-64-7
Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets …
Formula:
C16H15N3O2
Purity:
99.19% - 99.76%
Color and Shape:
Solid
Molecular weight:
281.31
Ref: TM-T3586
| 2mg | 34.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 307.00 € | ||
| 200mg | 439.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AMPK activator 2
CAS:2410961-69-0
AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting …
Formula:
C13H18F3N5
Purity:
99.86%
Color and Shape:
Liquid
Molecular weight:
301.31
Ref: TM-T60675
| 1mg | 86.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 296.00 € | ||
| 25mg | 497.00 € | ||
| 50mg | 709.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,838.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Avitinib maleate
CAS:1557268-88-8
Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.
Formula:
C30H30FN7O6
Purity:
98% - 99.77%
Color and Shape:
Solid
Molecular weight:
603.61
Ref: TM-T3721
| 5mg | 72.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Daphnetin
CAS:486-35-1
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR …
Formula:
C9H6O4
Purity:
98.33% - 99.82%
Color and Shape:
Solid
Molecular weight:
178.14
Ref: TM-T2851
| 10mg | 50.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 239.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
