PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
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AS-041164
CAS:6318-41-8
AS-041164: Oral PI3Kγ inhibitor, IC50 70 nM; weaker on PI3Kα/β/δ; anti-inflammatory.
Formula:
C11H7NO4S
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
249.24
Ref: TM-T21938
| 10mg | 44.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 129.00 € | ||
| 100mg | 201.00 € | ||
| 200mg | 266.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
PQR530
CAS:1927857-61-1
PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and …
Formula:
C18H23F2N7O2
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
407.42
Ref: TM-T16567
| 1mg | 34.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
YM-201636
CAS:371942-69-7
YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to …
Formula:
C25H21N7O3
Purity:
93.28% - 98.3%
Color and Shape:
Solid
Molecular weight:
467.48
Ref: TM-T6110
| 1mg | 47.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 785.00 € | ||
| 500mg | 1,607.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Polygalasaponin F
CAS:882664-74-6
Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.
Formula:
C53H86O23
Purity:
98% - 99.83%
Color and Shape:
Solid
Molecular weight:
1091.24
Ref: TM-T3826
| 20mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 118.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Isorhamnetin
CAS:480-19-3
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.
Formula:
C16H12O7
Purity:
92.82% - 98.97%
Color and Shape:
Solid
Molecular weight:
316.26
Ref: TM-T2836
| 1mg | 40.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 386.00 € | ||
| 100mg | 548.00 € | ||
| 500mg | 1,179.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Pilaralisib
CAS:934526-89-3
Pilaralisib (XL-147) is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 …
Formula:
C25H25ClN6O4S
Purity:
98.24% - 99.61%
Color and Shape:
Solid
Molecular weight:
541.02
Ref: TM-T2365
| 2mg | 49.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 388.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
SF2523
CAS:1174428-47-7
SF2523 is a highly selective and potent inhibitor.
Formula:
C19H17NO5S
Purity:
97.78% - 98.06%
Color and Shape:
Solid
Molecular weight:
371.41
Ref: TM-T3986
| 1mg | 37.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 433.00 € | ||
| 100mg | 639.00 € | ||
| 500mg | 1,336.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
LY-294002 hydrochloride
CAS:934389-88-5
LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome …
Formula:
C19H17NO3·HCl
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
343.81
Ref: TM-T4079
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 440.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
DS-7423
CAS:1222104-37-1
DS-7423: a dual PI3K/mTOR inhibitor; IC50s-PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: …
Formula:
C22H27F3N10O2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
520.51
Ref: TM-T36083
| 1mg | 127.00 € | ||
| 5mg | 283.00 € | ||
| 10mg | 433.00 € | ||
| 25mg | 708.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,378.00 € | ||
| 1mL*10mM (DMSO) | 322.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Gedatolisib
CAS:1197160-78-3
Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR …
Formula:
C32H41N9O4
Purity:
98% - 99.48%
Color and Shape:
Solid
Molecular weight:
615.73
Ref: TM-T1970
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 417.00 € | ||
| 100mg | 616.00 € | ||
| 500mg | 1,296.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
KU-0060648
CAS:881375-00-4
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 …
Formula:
C33H34N4O4S
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
582.71
Ref: TM-T6557
| 1mg | 58.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 441.00 € | ||
| 100mg | 631.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Desmethyl-VS-5584
CAS:1246535-95-4
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR …
Formula:
C16H20N8O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T4199
| 1mg | 58.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 148.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 421.00 € | ||
| 50mg | 620.00 € | ||
| 100mg | 884.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Duvelisib
CAS:1201438-56-3
Duvelisib (INK1197, IPI-145) is a selective inhibitor of phosphatidylinositol 3-kinase (PI3K) and p100δ.Cost-effective and quality-assured.
Formula:
C22H17ClN6O
Purity:
99.38% - 99.45%
Color and Shape:
Solid
Molecular weight:
416.86
Ref: TM-T1988
| 2mg | 47.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 50mg | 152.00 € | ||
| 100mg | 238.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
PIK-75
CAS:372196-67-3
PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formula:
C16H14BrN5O4S
Purity:
100% - 99.88%
Color and Shape:
Solid
Molecular weight:
452.28
Ref: TM-T2667
| 5mg | 45.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 276.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Vacuolin-1
CAS:351986-85-1
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.
Formula:
C26H24IN7O
Purity:
98.45% - 99.45%
Color and Shape:
Solid
Molecular weight:
577.42
Ref: TM-T21992
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 341.00 € | ||
| 100mg | 530.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
CZC24832
CAS:1159824-67-5
CZC24832 is a selective inhibitor of PI 3-kinase γ.
Formula:
C15H17FN6O2S
Purity:
99.08% - 99.12%
Color and Shape:
Solid
Molecular weight:
364.4
Ref: TM-T1949
| 1mg | 51.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 234.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Deoxyelephantopin
CAS:29307-03-7
Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.
Formula:
C19H20O6
Purity:
99.6% - 99.69%
Color and Shape:
Solid
Molecular weight:
344.36
Ref: TM-TN1079
| 1mg | 94.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 342.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Acalisib
CAS:870281-34-8
Acalisib (CAL-120) (GS-9820) is a potent and selective inhibitor of PI3Kδ.
Formula:
C21H16FN7O
Purity:
98.99% - ≥95%
Color and Shape:
Solid
Molecular weight:
401.4
Ref: TM-T2682
| 5mg | 50.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 409.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Parsaclisib hydrochloride
CAS:1995889-48-9
Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent …
Formula:
C20H23Cl2FN6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
469.34
Ref: TM-T28297
| 25mg | 1,141.00 € | ||
| 50mg | 1,526.00 € | ||
| 100mg | 2,433.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Umbralisib hydrochloride
CAS:1532533-78-0
Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.
Formula:
C31H25ClF3N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
608.01
Ref: TM-T17066
| 2mg | 57.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
