PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 231 products of "PI3K"
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Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48Heterophyllin B
CAS:Heterophyllin B hinders esophageal cancer cell adhesion/invasion via PI3K/AKT/β-catenin and gene regulation.Formula:C40H58N8O8Purity:99.12% - 99.85%Color and Shape:SolidMolecular weight:778.94AMG319
CAS:AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.Formula:C21H16FN7Purity:98.9% - 99.24%Color and Shape:Crystalline SolidMolecular weight:385.4P7C3-A20
CAS:P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.Formula:C22H19Br2FN2OPurity:96.83% - ≥98%Color and Shape:SolidMolecular weight:506.21Voxtalisib
CAS:Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.Formula:C13H14N6OPurity:98.21% - 99.69%Color and Shape:SolidMolecular weight:270.29Ref: TM-T7014
1mg35.00€2mg50.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg117.00€25mg226.00€50mg364.00€100mg532.00€Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Formula:C31H24F3N5O3Purity:99.56% - 99.56%Color and Shape:White SolidMolecular weight:571.55Ref: TM-T4976
1mg46.00€2mg62.00€5mg90.00€1mL*10mM (DMSO)114.00€10mg166.00€25mg324.00€50mg425.00€100mg623.00€AZD-8835
CAS:AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).Formula:C22H31N9O3Purity:98.22% - 99.88%Color and Shape:SolidMolecular weight:469.54AS-604850
CAS:AS-604850: ATP-competitive PI3Kγ inhibitor, IC50 250 nM, 18x > PI3Kα, 80x > PI3Kδ/β.Formula:C11H5F2NO4SPurity:99.65%Color and Shape:SolidMolecular weight:285.22PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Formula:C14H16ClN3O4S2Purity:97.72%Color and Shape:SolidMolecular weight:389.88Ref: TM-T2616
1mg42.00€5mg85.00€1mL*10mM (DMSO)94.00€10mg105.00€25mg200.00€50mg305.00€100mg427.00€200mg613.00€CH5132799
CAS:CH5132799 has been used in trials studying the treatment of Solid Tumors.Formula:C15H19N7O3SPurity:99.41% - 99.87%Color and Shape:SolidMolecular weight:377.42Ref: TM-T2619
1mg60.00€2mg92.00€5mg137.00€10mg215.00€25mg399.00€50mg590.00€100mg838.00€500mg1,693.00€Seletalisib
CAS:Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).Formula:C23H14ClF3N6OPurity:99.81%Color and Shape:SolidMolecular weight:482.85Ref: TM-TQ0044
1mg54.00€2mg77.00€5mg114.00€1mL*10mM (DMSO)119.00€10mg178.00€25mg313.00€50mg447.00€100mg625.00€α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Formula:C18H30O2Purity:97.05% - 99.81%Color and Shape:Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:278.43GSK2636771
CAS:GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, andFormula:C22H22F3N3O3Purity:98.58% - ≥95%Color and Shape:SolidMolecular weight:433.42Ref: TM-T2073
1mg40.00€2mg54.00€5mg84.00€1mL*10mM (DMSO)84.00€10mg142.00€25mg240.00€50mg340.00€100mg518.00€Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formula:C21H24ClN7OPurity:97.04%Color and Shape:SolidMolecular weight:425.91Ref: TM-T7015
1mg43.00€2mg56.00€5mg88.00€1mL*10mM (DMSO)96.00€10mg124.00€25mg207.00€50mg333.00€100mg477.00€SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purity:99.42% - 99.99%Color and Shape:SolidMolecular weight:443.85PIK-90
CAS:PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .Formula:C18H17N5O3Purity:98.25% - ≥95%Color and Shape:SolidMolecular weight:351.36A66
CAS:A66 is a specific and effective p110α inhibitor(IC50=32 nM).Formula:C17H23N5O2S2Purity:99.51% - ≥95%Color and Shape:SolidMolecular weight:393.53Ref: TM-T2418
2mg34.00€5mg52.00€1mL*10mM (DMSO)52.00€10mg79.00€25mg137.00€50mg234.00€100mg344.00€200mg485.00€Linperlisib
CAS:Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3KδFormula:C28H37FN6O5SPurity:99.01%Color and Shape:SolidMolecular weight:588.69Ref: TM-T6330
1mg34.00€2mg46.00€5mg66.00€1mL*10mM (DMSO)87.00€10mg90.00€25mg192.00€50mg295.00€100mg462.00€Vps34-IN-4
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formula:C21H25N7OPurity:98.6%Color and Shape:SolidMolecular weight:391.47Ref: TM-T7944
1mg63.00€5mg137.00€1mL*10mM (DMSO)150.00€10mg215.00€25mg378.00€50mg537.00€100mg713.00€200mg982.00€740 Y-P
CAS:740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!Formula:C141H222N43O39PS3Purity:98.3% - 99.87%Color and Shape:SolidMolecular weight:3270.7
