Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44YS-49
CAS:<p>YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).</p>Formula:C20H20BrNO2Purity:99.65%Color and Shape:SolidMolecular weight:386.28Cyclo(RADfK)
CAS:<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Formula:C28H43N9O7Purity:>99.99%Color and Shape:SolidMolecular weight:617.7Trimethyloctadecylammonium bromide
CAS:<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Formula:C21H46N·BrPurity:99.09%Color and Shape:Solid SolidMolecular weight:392.5E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formula:C17H12N4O2SPurity:98.31% - 99.11%Color and Shape:SolidMolecular weight:336.37CK-636
CAS:<p>CK-636 (CK-0944636), an Arp2/3 complex inhibitor, can inhibit actin polymerization induced by the human, fission yeast and bovine Arp2/3 complex.</p>Formula:C16H16N2OSPurity:98.1% - 98.88%Color and Shape:SolidMolecular weight:284.38BRD9876
CAS:<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Formula:C16H14N2Purity:97.81%Color and Shape:SolidMolecular weight:234.3N-Phenylbenzylamine
CAS:<p>A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization</p>Formula:C13H13NPurity:98.75%Color and Shape:Colorless To Pale Yellow Crystalline PowderMolecular weight:183.25Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formula:C21H24ClN2NaO4SPurity:99.82%Color and Shape:SolidMolecular weight:458.93Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formula:C35H49N11O9S2·xC2H4O2Purity:99.7% - 99.87%Color and Shape:SolidMolecular weight:831.96 (free base)KNK437
CAS:<p>KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).</p>Formula:C13H11NO4Purity:98.90%Color and Shape:SolidMolecular weight:245.23TAS-301
CAS:<p>TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.</p>Formula:C23H19NO3Purity:99.55%Color and Shape:SolidMolecular weight:357.4GNF-7
CAS:<p>GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.</p>Formula:C28H24F3N7O2Purity:97.05% - 99.7%Color and Shape:SolidMolecular weight:547.53Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59Hispidin
CAS:<p>Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties</p>Formula:C13H10O5Purity:98.27%Color and Shape:White Crystalline PowderMolecular weight:246.22Aurothiomalate sodium
CAS:<p>Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.</p>Formula:C4H3AuNa2O4SPurity:99.66%Color and Shape:SoildMolecular weight:390.07KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4Arginine-glycine-aspartic acid
CAS:<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Formula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56Empesertib
CAS:<p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.</p>Formula:C29H26FN5O4SPurity:97.45% - 99.4%Color and Shape:SolidMolecular weight:559.61MAP4343
CAS:<p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>Formula:C22H34O2Purity:97.024%Color and Shape:SolidMolecular weight:330.5HSF1A
CAS:<p>HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.</p>Formula:C21H19N3O2S2Purity:98.89%Color and Shape:SolidMolecular weight:409.52Milnacipran ((1S-cis) hydrochloride)
CAS:<p>Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.</p>Formula:C15H23ClN2OPurity:99.81%Color and Shape:SolidMolecular weight:282.81TNIK-IN-2
CAS:<p>TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.</p>Formula:C22H19N3O3Purity:99.54%Color and Shape:SolidMolecular weight:373.4Curvulin
CAS:<p>Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.</p>Formula:C12H14O5Purity:98.65%Color and Shape:SolidMolecular weight:238.24AMP-945
CAS:<p>AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.</p>Formula:C28H32F3N5O2Purity:99.76%Color and Shape:SolidMolecular weight:527.58TASP0415914
CAS:<p>TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T</p>Formula:C13H17N5O3SPurity:98.14%Color and Shape:SolidMolecular weight:323.37Mavacamten
CAS:<p>Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)</p>Formula:C15H19N3O2Purity:99.53% - 99.98%Color and Shape:SolidMolecular weight:273.33Smurf1-IN-A01
CAS:<p>Smurf1-IN-A01 is a potent Smurf1 inhibitor enhancing BMP-2, with a Kd of 3.664 nM, preventing Smad1/5 degradation.</p>Formula:C22H20ClF3N4O3SPurity:99.46%Color and Shape:SolidMolecular weight:512.93Hydroxy-Dynasore
CAS:<p>Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,</p>Formula:C18H14N2O5Purity:97.60% - >99.99%Color and Shape:SolidMolecular weight:338.31TB500
CAS:<p>TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.</p>Formula:C38H68N10O14Purity:99.51%Color and Shape:SolidMolecular weight:889.01PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Formula:C24H21N5O2Purity:99.33%Color and Shape:SolidMolecular weight:411.46ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Formula:C28H24Cl2FN5O2Purity:97.01% - 98.38%Color and Shape:SolidMolecular weight:552.43HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Formula:C13H15N3O2SPurity:99.44%Color and Shape:Pale Yellow Crystalline SolidMolecular weight:277.34HM03
CAS:<p>HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.</p>Formula:C26H27ClN4O2Purity:97.15%Color and Shape:SolidMolecular weight:462.97CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34Taurolithocholic acid sodium salt
CAS:<p>Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but</p>Formula:C26H44NNaO5SPurity:99.79% - 99.93%Color and Shape:SolidMolecular weight:505.69Multi-kinase inhibitor 1
CAS:<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Formula:C20H17F3N4O3Purity:99.34%Color and Shape:SolidMolecular weight:418.37BAY1125976
CAS:<p>BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)</p>Formula:C23H21N5OPurity:99.28% - ≥98%Color and Shape:SolidMolecular weight:383.45A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4Desmethylglycitein
CAS:<p>Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has</p>Formula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Hexapeptide-10 Acetate
<p>Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.</p>Formula:C30H57N7O10Purity:98.84%Color and Shape:SolidMolecular weight:675.81KW-2478
CAS:<p>KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.</p>Formula:C30H42N2O9Purity:98.68% - 99.52%Color and Shape:SolidMolecular weight:574.66PU-H54
CAS:<p>PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.</p>Formula:C18H19N5SPurity:99.13%Color and Shape:SolidMolecular weight:337.44BIIB021
CAS:<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Formula:C29H48N12O12S2Purity:>99.99%Color and Shape:SolidMolecular weight:820.89Spastazoline
CAS:<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formula:C20H30N8Purity:99.23%Color and Shape:SolidMolecular weight:382.51Clanfenur
CAS:<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Formula:C16H15ClFN3O2Purity:99.93%Color and Shape:SolidMolecular weight:335.76MMAF
CAS:<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Formula:C39H65N5O8Purity:97.00% - 99.88%Color and Shape:SolidMolecular weight:731.96Sovilnesib
CAS:<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Formula:C26H34F2N6O4SPurity:99.57%Color and Shape:SolidMolecular weight:564.65Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Formula:C30H33ClN4O2Purity:98% - 99.09%Color and Shape:SolidMolecular weight:517.06Gap 26
CAS:<p>Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.</p>Formula:C70H107N19O19SPurity:98.26%Color and Shape:SolidMolecular weight:1550.78Dasatinib N-oxide
CAS:<p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>Formula:C22H26ClN7O3SPurity:98.54% - 99.94%Color and Shape:SolidMolecular weight:504PF04929113
CAS:<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Formula:C25H30F3N5O4Purity:99.04%Color and Shape:SolidMolecular weight:521.53XL888
CAS:<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Formula:C29H37N5O3Purity:99.18%Color and Shape:SolidMolecular weight:503.64HM03 trihydrochloride
CAS:<p>HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.</p>Formula:C26H30Cl4N4O2Color and Shape:SolidMolecular weight:572.35H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Formula:C23H38N10O10Purity:>99.99%Color and Shape:SolidMolecular weight:614.61PKC ζ pseudosubstrate acetate
<p>PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.</p>Formula:C78H132N30O18Purity:98.78%Color and Shape:SolidMolecular weight:1778.10ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formula:C30H30F3N5OPurity:99.30%Color and Shape:SolidMolecular weight:533.59CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Formula:C26H32BrN5O6Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:590.47Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Formula:C19H18BrN3OPurity:98.32% - 99.98%Color and Shape:SolidMolecular weight:384.27AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formula:C29H42F3N9O9Purity:98.99% - 99.54%Color and Shape:SolidMolecular weight:717.69Doxepin
CAS:<p>Doxepin: tricyclic antidepressant, inhibits serotonin/norepinephrine reuptake, helps atopic dermatitis/urticaria, cognitive protector, anti-inflammatory.</p>Formula:C19H21NOColor and Shape:SolidMolecular weight:279.38[Ala113]-MBP (104-118) acetate
<p>[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.</p>Formula:C69H108N20O21Purity:97.72%Color and Shape:SolidMolecular weight:1553.74Fingolimod
CAS:<p>Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).</p>Formula:C19H33NO2Purity:99.53% - 99.6%Color and Shape:SolidMolecular weight:307.47Mps1-IN-1 dihydrochloride
CAS:<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Formula:C28H35Cl2N5O4SColor and Shape:SolidMolecular weight:608.58Aficamten
CAS:<p>Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.</p>Formula:C18H19N5O2Purity:99.19% - 99.57%Color and Shape:SolidMolecular weight:337.38MMAD
CAS:<p>MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).</p>Formula:C41H66N6O6SPurity:99.25% - 99.91%Color and Shape:SolidMolecular weight:771.06CK-869
CAS:<p>CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.</p>Formula:C17H16BrNO3SPurity:99.85%Color and Shape:SolidMolecular weight:394.28Imatinib
CAS:<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Formula:C29H31N7OPurity:99.42% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6PIR 3.5
CAS:<p>PIR 3.5 (6,6′-Dithiodi(2-naphthol)) is a negative control of IPA 3 which is a Pak1 inhibitor.</p>Formula:C20H14O2S2Purity:98.08%Color and Shape:SolidMolecular weight:350.45Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Formula:C28H26N4O3Purity:99.24% - 99.82%Color and Shape:Off-White PowderMolecular weight:466.53XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54MitoBloCK-10
CAS:<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Formula:C12H8FN3O3SPurity:99.51%Color and Shape:SolidMolecular weight:293.27TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33Flumatinib
CAS:<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Formula:C29H29F3N8OPurity:99.39% - 99.95%Color and Shape:SolidMolecular weight:562.59OSU-T315
CAS:<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formula:C30H30F3N5OPurity:98.69%Color and Shape:SolidMolecular weight:533.59Onalespib
CAS:<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Formula:C24H31N3O3Purity:98.05% - 99.66%Color and Shape:SolidMolecular weight:409.52TPPB
CAS:<p>TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).</p>Formula:C27H30F3N3O3Purity:97.71% - 98.00%Color and Shape:SolidMolecular weight:501.54Triciribine
CAS:<p>Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.</p>Formula:C13H16N6O4Purity:99.01% - 99.87%Color and Shape:SolidMolecular weight:320.3Tirbanibulin
CAS:<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Albendazole sulfoxide
CAS:<p>Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.</p>Formula:C12H15N3O3SPurity:97.29%Color and Shape:White To Off-White PowderMolecular weight:281.33Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65Flumatinib mesylate
CAS:<p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>Formula:C30H33F3N8O4SPurity:99.82%Color and Shape:SolidMolecular weight:658.69D-64131
CAS:<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Formula:C16H13NO2Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:251.28KBU2046
CAS:<p>KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.</p>Formula:C15H11FO2Purity:99.89%Color and Shape:SolidMolecular weight:242.24Procyanidin A1
CAS:<p>Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.</p>Formula:C30H24O12Purity:99.52%Color and Shape:SolidMolecular weight:576.5HSP27 inhibitor J2
CAS:<p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>Formula:C13H12O4SPurity:99.51%Color and Shape:SolidMolecular weight:264.3GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formula:C43H46F3N7O7SPurity:98.78% - >99.99%Color and Shape:SolidMolecular weight:861.93Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Formula:C18H14N2O4Purity:95.85% - 99.22%Color and Shape:SolidMolecular weight:322.31NRX-252262
CAS:<p>NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50：3.8 nM)</p>Formula:C23H17Cl2F3N2O4SPurity:98.94% - 99.87%Color and Shape:SolidMolecular weight:545.36Borussertib
CAS:<p>Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)</p>Formula:C36H32N6O3Purity:99.00%Color and Shape:SolidMolecular weight:596.68Ingenol
CAS:<p>Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.</p>Formula:C20H28O5Purity:99.78% - 99.87%Color and Shape:SolidMolecular weight:348.43BX517
CAS:<p>BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.</p>Formula:C15H14N4O2Purity:99.26%Color and Shape:SolidMolecular weight:282.32-hydroxy Flutamide
CAS:<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Formula:C11H11F3N2O4Purity:99.45% - 99.82%Color and Shape:SolidMolecular weight:292.21Sotrastaurin
CAS:<p>Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).</p>Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48PF-431396
CAS:<p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>Formula:C22H21F3N6O3SPurity:98.83% - 99.82%Color and Shape:SolidMolecular weight:506.5Decursinol angelate
CAS:<p>Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.</p>Formula:C19H20O5Purity:99.93%Color and Shape:SolidMolecular weight:328.36
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