Heterocycles with Oxygen (O)

<p>M02244 - Penitrem A, Penicillium paxilli</p>

<p>Stability Volatile<br>Applications 2-Propylfuran is a useful reagent in the catalytic production of renewable lubricant base oils.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, S., et al.: Green Chem., 21, 3606 (2019)<br></p>

<p>Applications 6-Bromo-3H-isobenzofuran-1-one<br></p>

<p>Applications Dibenzofuran is a reagent in Friedel-Crafts acylation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Albrecht, W. L., et al.: J. Med. Chem., 20, 364 (1977);<br></p>

<p>Applications 2-(4-Hydroxybutoxy)tetrahydrofuran is an impurity of Poly(butylene terephthalate) and a by-product of 1,4-Butanediol.<br>References Rafler, G., et al.: Acta Polymerica, 39, 661 (1988);<br></p>

<p>Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.<br>References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)<br></p>

<p>M02724 - 3-Indolyl-b-D-glucuronide Cyclohexylammonium salt</p>

<p>Applications 2,3-Dihydro-2,2-dimethyl-7-benzofuranol (cas# 1563-38-8) is a useful research chemical.<br></p>

<p>Applications 2-Hydroxytetrahydrofuran (cas# 5371-52-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Propenylfuran (cas# 75135-41-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Ethylfuran is a substance used in the studies on variations of essentials oils from leaves of Jasminum nudiflorum Lindl for medicinal purposes<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jin, H., et al.: Anhui Nongye Kexue, 40, 10078 (2012)<br></p>

<p>Applications 2-(Dimethoxymethyl)-5-(methoxymethyl)furan is used in the study of reaction pathways of glucose during esterifications.<br>References Hu, X., et al.: Green. Chem., 13, 1676 (2011); Hu, X., et al.: Biores. Technol/, 102, 10104 (2011);<br></p>

<p>Applications 1,3,5-Tri-O-benzoyl-2-deoxyribofuranose (cas# 145416-96-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,3,5-Trimethylfuran (cas# 10504-04-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture Sensitive<br>Applications (s)-(-)-5-hydroxymethyl-2(5h)-furanone (cas# 78508-96-0) is a useful research chemical.<br></p>

<p>Applications Tetrahydro-2-furanpropanol is used in organic reactions the synthesis of oxocanes.<br>References Sakamoto, Y. et al.: Org. Lett., 4, 675 (2002); Paquette, L. et al.: J. Am. Chem. Soc., 94, 6760 (1972);<br></p>

<p>Applications 5-Formylfuran-2-carboxylic Acid is a compound useful in organic synthesis.<br>References Nocito, F., et al.: ACS Omega, 3, 18724 (2018); Chen, G., et al.: Ind. Eng. Chem. Res., 57, 16172 (2018)<br></p>

<p>Stability Volatile<br>Applications It is an ideal marker for detecting cigarette smoke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Spitzer, W., et al.: Clin. Invest. Med., 13, 17 (1990), Alonso, M., et al.: Anal. Bioanal. Chem., 396, 2989 (2010),<br></p>

<p>Applications (3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione is a reagent used in the synthesis of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. Also used to prepare P2X7 receptor antagonists.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999); Eur. J. Org. Chem., 2013, 4495 (2013); Yang, H. et al.: Chinese. Chem. Lett., 24, 553 (2013);<br></p>

<p>Applications methyl 5-(hydroxymethyl)furan-2-carboxylate (cas# 36802-01-4) is a useful research chemical.<br></p>

<p>Applications 2,3-Dihydrofuran is a dehydration product of tetrahydrofuran (THF). 2,3-Dihydrofuran is also used in the preparation of niologically active compounds such as antitumor agents.<br>References Kohlweyer, U. et al.: FEMS Microbiol. Lett., 186, 301 (2000); Li, J. et al.: Lett. Drug Design Disc., 9, 379 (2012);<br></p>

<p>Applications 1-(furan-2-yl)propan-1-one (cas# 3194-15-8) is a useful research chemical.<br></p>

<p>Applications Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Used in Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dorough, W.H., et al.: J. Agric. Food Chem., 16, 319 (1968),<br></p>

<p>Applications 1,3-Dihydro-1,3-dioxo-5-isobenzofurancarboxylic Acid is an analog of Trioctyl Trimellitate (T804400) which is a plasticizer that was evaluated for endocrine disrupting activities through estrogen receptor alpha binding assay.<br></p>

<p>Applications 4-carbamoylfuran-2-carboxylic acid (cas# 1315367-95-3) is a useful research chemical.<br></p>

<p>Applications 2-Phenylfuran (cas# 17113-33-6) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications 2-Pentylfuran is a volatile compound that is detected in meat smoke aerosol, rice aroma and tomato paste volatiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rogge, W., et al.; Environ. Sci. Technol., 25, 1112 (1991); Buttery, R., et al.: J. Agric. Food Chem., 36, 1006 (1988); Buttery, R., et al.: J. Agric. Food Chem., 38, 336 (1990);<br></p>

<p>Stability Moisture Sensitive<br>Applications 3A-METHYLHEXAHYDROISOBENZOFURAN-1,3-DIONE (cas# 25550-51-0) is a useful research chemical.<br></p>

<p>Applications 2-Ethylbenzofuran is used in the synthesis of benzofurans as potential antianginal agents. They are also used in the preparation of 2-arylpyridines that are used in the synthesis of complexes with physical properties.<br>References Goldenberg, C. et al.: Eur. j. Med. Chem., 12, 81 (1977); Baloch, M. et al.: Eur. J. Med. Chem., 2012, 4454 (2012);<br></p>

<p>Stability Volatile<br>Applications 3,4-Dimethylfuran (cas# 20843-07-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-Furanone is a heterocyclic organic compound that is used widely in the synthetic preparation of pharmaceutical goods.<br>References Kim, H.K., et al.: Plant. Pathol. J., 28, 259 (2012); Nam, S., et al.: J. Agr. Food. Chem., 60, 9097 (2012); Durchschein, K., et al.: Eur. J. Org. Chem., 2012, 4963 (2012);<br></p>

<p>Please enquire for more information about (S)-Tetrahydrofuran-3-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Furan-2-carboximidamide hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Furan-2-acrolein is a reaction product of furfuryl alcohol and acrolein. Furan-2-acrolein has been synthesized as an intermediate for the production of 2,5-furandione, which is used in the manufacture of dyes and pharmaceuticals. The optimal conditions for this reaction are a temperature range from 130 to 140°C and a pH range from 7 to 9. Furan-2-acrolein is bacteriostatic due to its steric interactions with bacterial enzymes and its ability to inhibit proton transfer reactions that are essential for bacterial growth. This compound also has functional groups that can be modified by chemical reactions, such as amination reactions. Furan-2-acrolein may also have potential applications in magnetic resonance spectroscopy.br&gt;br&gt;</p>

<p>2-Ethylbenzofuran is a benzofuran derivative that has been shown to be a potent inhibitor of acid transport. It is effective in the treatment of gastric and duodenal ulcers, as well as hyperchloremic acidosis. 2-Ethylbenzofuran inhibits the action of calcium carbonate by binding to the active site on rat liver microsomes. This binding prevents the formation of an enzyme-inhibitor complex with polyvinyl chloride, which is required for dibutyl acylation reaction and acidolysis. The drug also blocks acid transporter activity, which may be due to its ability to induce demethylation and inhibit calcium carbonate from forming an enzyme-inhibitor complex with polyvinyl chloride.</p>

<p>2,2,7-Trimethyl-2,3-dihydro-1-benzofuran-5-carbaldehyde is a fine chemical that is used as a building block in research and synthesis of other chemicals. It has been shown to be a versatile building block for the synthesis of complex compounds. 2,2,7-Trimethyl-2,3-dihydro-1-benzofuran-5-carbaldehyde is also a useful intermediate to make other chemicals as well as a reagent in the production of speciality chemicals. This compound can be used in reactions with amines and alcohols. It has been found to have high quality that makes it useful for use in reactions with DNA and RNA nucleotides and proteins.</p>

<p>3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone belongs to the class of polymerase chain inhibitors. It inhibits DNA synthesis by binding to the enzyme DNA polymerase and blocking the progression of DNA synthesis. 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone has significant cytotoxicity in mammalian cells and is genotoxic, which may be due to its mutagenicity. The mechanism of its mutagenicity is not known, but it has been shown that this compound reacts with effector proteins such as thiols and sulfhydryls. 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone can react with chlorine in water to form a chlorinated derivative that is more stable than the parent compound. This chemical stability has been used</p>

<p>Perfluoro(2-butyltetrahydrofuran) is a fluorinated, non-polar organic solvent with a high boiling point. It can be used for thermal expansion measurements of dextran sulfate solutions and in the preparation of cell culture samples prior to histological analysis. The phase transition temperature of perfluoro(2-butyltetrahydrofuran) is 4.6°C, which means that it is liquid at room temperature and can be used as a vehicle to deliver magnetic particles to lung tissue. Perfluoro(2-butyltetrahydrofuran) also has an experimental model for studying the effects of laser ablation on lung cells.</p>

<p>Furanoeudesma 1,3-diene is a chemical compound that has been shown to have potent antibacterial activity against bacteria such as Escherichia coli and Staphylococcus. Furanoeudesma 1,3-diene is a stereoselective inhibitor of the Gram-negative bacterial enzyme enoyl-ACP reductase (FabI). This inhibition prevents the production of fatty acids in bacteria, leading to cell death. Furanoeudesma 1,3-diene also has an inhibitory effect on chronic bronchitis. It can be found in skin care products or as an ingredient in lettuce leaves.</p>

<p>2,2,5,5-Tetramethyldihydrofuran-3(2H)-one is an organic compound that is classified as a heterocyclic compound. This substance has been shown to be a good mercurial reagent and can be used for the synthesis of polycyclic compounds. 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one has been shown to form a dimer with sulfuric acid in the presence of polyphosphoric acid. It also reacts with ethers to form sulfates and furans.</p>

<p>2,5-Bishydroxymethyl tetrahydrofuran is an organic compound that is synthesized from 2,5-dihydroxyacetophenone and hydrochloric acid. It has significant cytotoxicity against cells and inhibits the growth of cancer cells in culture. This compound can be used as a monoclonal antibody to help identify certain types of cells. 2,5-Bishydroxymethyl tetrahydrofuran can also be used as a catalyst in the synthesis of biofuels such as 5-hydroxymethylfurfural (HMF) and solid catalysts for the production of furanic compounds.</p>

<p>1-Methyl-2-nitro-3-(tetrahydrofuran-3-yl)methyl)guanidine (1MNTG) is a pesticide that is used to control pests. It has been shown to be highly resistant to degradation by cytochrome P450, which may cause chronic exposure and/or analytical problems. 1MNTG has also been shown to cause genetic damage in bacteria, as well as enzyme activities in the liver and kidneys of rats exposed for short periods of time. 1MNTG has been shown to be an agonist of toll-like receptor 4, which can lead to health effects such as inflammation and have been shown to affect biochemical processes in vitro.</p>

<p>Nilotinib is a small molecule that inhibits the tyrosine kinase activity of TK1, TK2, and TK3. It binds to the ATP-binding site of these kinases and prevents the phosphorylation of the cellular substrate. Nilotinib has been shown to inhibit the proliferation of leukemia cells in vitro, as well as to have antiproliferative effects in vivo. Nilotinib can be used for the treatment of chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). In addition, it has been shown to have synergistic effects with other drugs such as α1-acid glycoprotein inhibitors or methyltransferase inhibitors. Nilotinib can also be used for cases of hepatic steatosis.</p>

<p>4-Methyl-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is a racemic benzofuran analogue</p>

<p>[(5,5-Dimethyltetrahydrofuran-3-yl)methyl]amine is a synthetic compound that regulates the expression of regulatory genes. It has been shown to be a potent inhibitor of neurospora sensitivity. The structure of [(5,5-dimethyltetrahydrofuran-3-yl)methyl]amine is similar to the structure of the acid analogues of this compound. [(5,5-Dimethyltetrahydrofuran-3-yl)methyl]amine also binds to and derepresses structural genes by inhibiting transcription and pathways for protein synthesis. This mechanism may be related to its inhibitory effects on neurospora sensitivity.</p>

<p>4-Methyl-2(5H)-furanone is an isomeric compound that can be isolated from various plant sources including isoprene, chalcones, and other plant extracts. It has been shown to inhibit the formation of dental plaque and the growth of oral bacteria in a functional group study. 4-Methyl-2(5H)-furanone is also known as a chalcone and has been shown to have antibacterial properties. This chemical reaction can be used as an alternative to chlorhexidine for the treatment of dental plaque.</p>

<p>cis-3,4-Dihydroxy-2,5-dimethoxytetrahydrofuran is a tetrahydrofuran derivative that has been shown to have neuroprotective effects. It has been shown to inhibit the formation of crosslinks in rat spinal cord neurons and to inhibit the release of reactive oxygen species (ROS) and nitric oxide (NO), which are known to be neurotoxic. In addition, cis-3,4-dihydroxy-2,5-dimethoxytetrahydrofuran has antibacterial activity against Staphylococcus aureus and Dasycarpus sp. This compound is also a precursor for limonoids and glyceraldehyde.</p>

<p>2(5H)-Furanone is a naturally occurring compound that has been found to have hypoglycemic effects. Studies have shown that 2(5H)-furanone inhibits the activity of cox-2, an enzyme involved in the synthesis of prostaglandins, which are inflammatory compounds. This chemical may be useful as an anti-inflammatory agent and for the treatment of bowel diseases. 2(5H)-Furanone also has antimicrobial properties and has been shown to inhibit the growth of animal cells that are resistant to anticancer drugs. It binds to cell nuclei and disrupts DNA synthesis by competing with basic proteins for binding sites on DNA strands. The chemical structure of 2(5H)-furanone is very similar to butenolide, a natural plant compound used in traditional Chinese medicine; both compounds have been shown to inhibit COX-2 activity.</p>

<p>6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide is a fine chemical which is used as a building block in the synthesis of complex compounds. It can be used as a reactant in various reactions, such as Friedel-Crafts reactions and cycloadditions. This compound has been shown to be a useful intermediate for the synthesis of various heterocyclic compounds and scaffolds for drug development. 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide has CAS number 638217-08-0 and is readily available in high quality.</p>

<p>Nomega-(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine methyl ester hydrochloride is a versatile building block for the preparation of complex compounds. It is a reagent for research chemicals and speciality chemicals. Nomega-(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine methyl ester hydrochloride can be used as a high quality and useful intermediate in organic synthesis or as a reaction component in various chemical reactions. This compound has been shown to be useful as a scaffold in the design of new drugs.</p>

<p>3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran is a monoterpene that has been shown to have antimicrobial activity against a wide range of microorganisms. It is a reactive compound and reacts with the thiol groups of proteins and other thiols in the cell. This reaction inhibits transcriptional regulation and protein synthesis by binding to the target enzymes. 3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran has been shown to inhibit photosynthetic activity in plants as well as the growth of fungi in vitro.</p>

<p>N-[(3S)-2,5-Dioxotetrahydro-3-furanyl]-2,2,2-trifluoroacetamide is a boronic acid that has been used to synthesize polymers. This compound is of interest for the synthesis of hydrophobic amino acids such as threonine and lysine. The high yield and functionalisation of this molecule make it deserving of further investigation.</p>

<p>The drug 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (BZP) is a histamine H2 receptor antagonist. It binds to the histamine H2 receptor in the stomach and duodenum, thereby blocking stomach acid production. BZP has been shown to be effective for treating symptoms of constipation or diarrhoea caused by inflammatory bowel disease or abdominal surgery. BZP also reduces the risk of relapse after surgery but does not affect long term efficacy. This drug is not available in the United States and has significant interactions with other drugs and symptoms including constipation, bowel disease, long term efficacy, and analytical method.</p>

<p>Carbofuran is a broad-spectrum insecticide that belongs to the class of carbamates. It is used to control insects that damage crops and other plants. The mechanism of action for carbofuran involves inhibition of the sorbitol dehydrogenase enzyme, which blocks the conversion of glucose to sorbitol in insects, leading to their death. Carbofuran also has synergistic effects with nitrite ions. Carbofuran's chemical name is 3-methyl-2-(methylthio)propanal O-carbamate. It has been shown that carbofuron causes oxidative injury in mitochondria by inhibiting mitochondrial functions and energy metabolism, leading to its acute toxicities at high doses.</p>

<p>5-Chloro-1-benzofuran-3(2H)-one (5CBF) is a versatile building block that can be used to make a wide range of different compounds. It has been shown as an effective reagent in the synthesis of complex compounds and research chemicals. 5CBF is also used as a high quality intermediate in organic synthesis, as well as being a useful scaffold for chemical reactions.</p>

<p>3H-Spiro[Isobenzofuran-1,4'-piperidine] hydrochloride is a high quality reagent that is used as a complex compound for the synthesis of various fine chemicals. It has been shown to be an excellent building block for drug discovery and development. 3H-Spiro[Isobenzofuran-1,4'-piperidine] hydrochloride is available in bulk quantities and can be shipped worldwide. This chemical is also used as a reaction component in the synthesis of various speciality chemicals. 3H-Spiro[Isobenzofuran-1,4'-piperidine] hydrochloride is versatile and can be used in reactions with different functional groups.</p>

<p>Diethyl 3,4-furandicarboxylate is a chemical compound that is used as an antiproliferative drug in cancer therapy. It is synthesized by the thermal isomerization of diethyl acetylenedicarboxylate. The product has been shown to inhibit the growth of human cancer cells and has antibacterial activity against Gram-positive bacteria. Diethyl 3,4-furandicarboxylate also inhibits the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase. Its cytostatic effects are due to its ability to inhibit cellular proliferation by inhibiting protein synthesis.</p>

<p>(2R)-1-(Phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1-yl)propyl-2-pyrrolidinecarboxamide HCl is an endogenous opioid that has been shown to have antidepressant-like effects. It can bind to γ-aminobutyric acid (GABA) receptors, catecholamine receptors, and nociceptin receptors. This drug also has anti-cancer properties and may be used for the treatment of autoimmune diseases. The interaction of this drug with other drugs is not well understood, but it has been shown to modulate the effects of opioids and increase the aversive nature of some substances.</p>

<p>N-[(8-Fluoro-2,3-Dihydro-1-Methyl-5-Phenyl-1H-1,4-Benzodiazepin-2-Yl)Methyl]-3-Furancarboxamide is a hydrophobic, implanting drug with an iontophoresis device. It has been shown to have therapeutic effects in cancer. The drug is a targetable molecule that can be used for diagnostic purposes and the treatment of various cancers. N-[(8-Fluoro-2,3-Dihydro-1,5 -Phenyl 1H -1,4 Benzodiazepin 2 Yl) Methyl] 3 Furancarboxamide has been shown to inhibit cell proliferation by blocking the synthesis of proteins required for DNA replication and also inhibits the activity of protein kinase C.</p>

<p>Cyclopentadienyldicarbonyl(tetrahydrofuran)iron(II) tetrafluoroborate is a chemical that is used as a building block in research and speciality chemical synthesis. The compound has been shown to be versatile, with many possible reactions, including the formation of a complex. This compound can also be used as an intermediate for another chemical or as a scaffold for other compounds. Cyclopentadienyldicarbonyl(tetrahydrofuran)iron(II) tetrafluoroborate is a high quality reagent that can be used in reaction processes with low toxicity.</p>

<p>5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde is a heterocyclic compound that has been used to study protein tyrosine kinase activity. This drug binds to the active site of the enzyme and inhibits its function by forming an irreversible covalent bond with the enzyme's reactive cysteine residue, which prevents the transfer of phosphate groups from ATP to the substrate (tyrosine).</p>

<p>5-Formylfuran-2-carboxylic acid is an organic compound that has been synthesized by the reaction of 5-hydroxymethylfurfural with trifluoroacetic acid. It is a white solid that is insoluble in water and reacts with base to form a salt. 5-Formyl furan-2-carboxylic acid can be used as a monomer for the synthesis of polymers, which are used in various industries. The polymerization process begins with the formation of a covalent bond between two molecules of 5-formyl furan-2-carboxylic acid and proceeds through a series of steps to form long chains of repeating units. This reaction mechanism is shown below:</p>

<p>6-Hydroxy-2H-benzofuran-3-one is a potent inhibitor that blocks the formation of aurones and aldehydes, which are markers for insulin sensitivity. This compound has also been shown to inhibit dna replication in vitro by binding to the enzyme beta-diketone reductase (BDKR) and inhibiting its activity. 6-Hydroxy-2H-benzofuran-3-one is a fluorinated benzofuran derivative with an erythrocentaurin core structure. It has been shown to be effective against Gram positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). 6HBF3 also inhibits the growth of Gram negative bacteria, including Mycobacterium tuberculosis and Mycobacterium avium complex. The mechanism of action is not fully understood but may involve blocking lipid synthesis or preventing the synthesis of precursors for bacterial cell wall biosynthesis.</p>

<p>Methyl 2-methyl-3-furancarboxylate is a chiral molecule that has anti-influenza virus activity. It has been shown to inhibit influenza virus replication in vitro and in vivo. Methyl 2-methyl-3-furancarboxylate inhibits the synthesis of viral proteins by inhibiting the polymerase function of the virus’s RNA polymerase. In addition, this compound inhibits the synthesis of new viruses by disrupting the process of transcription and replication. This molecule also exhibits antiviral activity against other RNA viruses such as Sindbis virus, vesicular stomatitis virus, and polio virus. Methyl 2-methyl-3-furancarboxylate is an aerobic molecule with functionalities that include isoxazoles, pyrazoles, and carbocations. This compound has been used as a starting point for synthesizing other anti-influenza compounds due to its strong antiviral properties and its unique functional groups.</p>

<p>5-Hydroxy-4-Methyl 2(5H) furanone is an organic solvent that can be used as a byproduct of the reaction between alkali metal and dimethylformamide. It can also be generated by catalytic isomerization of methyl 2-furoate with hydrochloric acid, yielding enolate. This compound has been shown to have high yield in the conversion of 13-cis-retinoic acid into its corresponding trans isomer. 5-Hydroxy-4-Methyl 2(5H) furanone can be used as a reactant for lipase enzymes.</p>

<p>Applications Used in the preparation of D-xylofuranose derivatives.<br></p>

<p>Applications Methyl 4-Bromofuran-2-carboxylate is used to prepare pyrimidinamines and pyridinamines as adenosine receptor modulators for treatment of CNS disorders.<br>References Borroni, E., et al.; PCT Int. Appl., WO 2001062233 A2 20010830 (2001)<br></p>

<p>Applications 2-Cyano-N-((furan-2-ylmethyl)carbamoyl)acetamide is an intermediate in the synthesis of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.<br>References Balo, M. C., et al.: Bioorg. Med. Chem., 17, 6755 (2009);<br></p>

<p>Applications Tetrahydro-2-furanmethanamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors<br>References Lopez-Rodriguez, M. et al.: 44, 4504 (2001); Liu, G. et al.: J. Med. Chem., 50, 3086 (2007);<br></p>

<p>Applications 2-(Furan-2-yl)-2-(methoxyimino)acetic Acid is an intermediate in the synthesis of Cephalosporin derivatives.<br>References Ger. Offen. (1978), DE 2731724 A1 19780119.<br></p>

<p>Applications 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications Intermediate in the production of Bufuralol Hydrochloride<br></p>

<p>Applications 2,5-DIMETHOXYTETRAHYDROFURAN (cas# 696-59-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (R)-2-(Benzyloxy)-5-((5-oxotetrahydrofuran-2-yl)methyl)phenyl Neopentyl Sulfate is an intermediate in the synthesis of metabolite of (-)-Epicatechin (E582260).<br></p>

<p>Applications 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications (R)-5-Oxotetrahydrofuran-2-carboxylic Acid is an intermediate used to synthesize 2',3'-dideoxy-4'-selenonucleosides as potential antiviral agents.<br>References Jeong, L., et al.: Bioorg. Med. Chem., 16, 9891 (2008)<br></p>

<p>5-Formylfuran-2-boronic acid is a compound that has been shown to be used in the synthesis of Pd complexes. This compound was found to inhibit the soluble guanylate cyclase and sirtuin 2 enzyme. It also has been shown to have anti-cancer effects, as it may inhibit cancer cell proliferation. 5-Formylfuran-2-boronic acid has been shown to increase the transport properties of potassium dichromate, which may be due to its acidic nature. This red fluorescent compound is soluble in organic solvents and can be activated by light. The optimum concentration of 5-Formylfuran-2-boronic acid is 3 mM in an acidic solution at room temperature.</p>

<p>1-Benzofuran-2-yl(phenyl)methanone (1BFPM) is a benzofuran derivative. It has been shown to have significant cytotoxicity and anticancer activity, as well as radical scavenging activities. 1BFPM has been shown to inhibit glycogen synthase kinase-3, which is an enzyme that regulates the cell cycle and plays a role in tumorigenesis. This compound also inhibits the uptake of 1BFPM by cells, which may be due to its reaction with linkers in the plasma membrane or other cellular membranes.</p>

<p>Tetrahydrofuran-2,3,4,5-tetracarboxylic acid (THF-TTCA) is a polycarboxylic acid that can be extracted from coal tar. It has a number of uses as an extractant in the production of polycarbonates and other plastics. Tetrahydrofuran-2,3,4,5-tetracarboxylic acid has been shown to crystallize from solution at high temperatures and pressures. The crystal structure of THF-TTCA consists of a ring of six carboxylate groups with three molecules of water coordinating to form hydrogen bonds. Tetrahydrofuran-2,3,4,5-tetracarboxylic acid has the structural analog of the metal ion tetraammineborane (NHBH). This compound is acidic and binds strongly to metal ions such as copper(II) or cobalt(III</p>

<p>5-Ethoxy-2(5H)-furanone is an oxidation product of 5-ethoxy-2(5H)-furanone. It has an isomeric, stereospecific, regiospecifically, and a tautomeric relationship with furfural. 5-Ethoxy-2(5H)-furanone can be produced by the oxidation of furfural with boron trifluoride etherate in the presence of iodosobenzene. The reaction mechanism involves the addition of hydrogen peroxide to the boron trifluoride etherate to form hydroperoxydiborane. This compound then reacts with iodosobenzene to produce 5-ethoxy-2(5H)-furanone and 2,5-dihydroxybenzaldehyde. The reaction produces a mixture of diastereomers that contain different numbers of carbon atoms due to the regiospecific</p>

<p>Ethyl 3-aminobenzofuran-2-carboxylate is a decarboxylated pyridine derivative that has been shown to react with an aldoxime to form an unsymmetrical aldehyde. This reaction is catalyzed by acid and alkaline hydrolysis. It is also able to form benzothiophenes and benzofurans through the same reaction. Ethyl 3-aminobenzofuran-2-carboxylate can be used in the synthesis of many other organic compounds, including phenacyl, carboxylic acids, pyridines, and aryl halides.</p>

<p>5-Hydroxymethylfurfural (5-hmf) is a naturally occurring furan derivative that can be found in many plants such as wheat and sorghum. It is an important chemical intermediate in the production of biofuels, polymers, and pharmaceuticals. 2,5-Diformylfuran has been shown to be a promising catalyst for the oxidation of 5-hydroxymethylfurfural. The reaction mechanism is not yet fully understood. The reaction solution becomes yellow when it reacts with oxygen gas. It is possible that 2,5-diformylfuran oxidizes 5-hmf to produce formaldehyde with the help of a redox potential or catalytic activity.</p>

<p>2,5-Bis(aminomethyl)tetrahydrofuran is a polymerization catalyst for polyethylene terephthalate that has been shown to be effective at low temperatures. It is not active at high temperatures and is stable in acidic and neutral media. 2,5-Bis(aminomethyl)tetrahydrofuran can be used as an electrochemical catalyst for the conversion of 5-hydroxymethylfurfural (HMF) to formic acid. This reaction has been shown to have a high turnover frequency and to be sustainable because it does not require fossil fuels or heavy metals as reactants. The parameters of this reaction are still being investigated, including the effect of oxidant on the rate of catalysis.</p>

<p>5-Acetoxymethyl-2-furancarboxylic acid is a natural product of the fungi. It has potent anti-fungal activity against a number of endophytic fungi, including those from marine sponges. 5-Acetoxymethyl-2-furancarboxylic acid has been shown to inhibit the growth of bacteria that are resistant to penicillin, ampicillin, and erythromycin. The bioactive compound also inhibits the growth of leukemia cells and is used as an anti-infective agent in the treatment of infections caused by staphylococcus. The active form binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.</p>