Building Blocks

<p>Applications 3-Chlorotoluene-2,4,6-d3 (CAS# 1219803-79-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,2-Dibromobenzene-d4 (CAS# 1643577-34-7) is a useful isotopically labeled research compound.<br></p>

<p>Stability Not Stable in Solution<br>Applications 4-Amino-5-[(dithiocarboxyamino)methyl]-2-methypyrimidine Ammonium Salt is an intermediate in the synthesis of Thiamine (T344185), an essential nutrient required for carbohydrate metabolism; also involved in nerve function.<br>References Kawaski, T., et al.: Methods Enzymol., 122, 15 (1986), Mascher, H., et al.: J. Pharm. Sci., 82, 56 (1993),<br></p>

<p>Applications 3-Chlorotoluene-d7 (CAS# 1219804-88-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications trans-β-Nitrostyrene, and its derivatives such as 3,4-methylenedioxy-β-nitrostyrene (MNS) and 4-O-benzoyl-3-methoxy-β-nitrostyrene (BMNS), has shown to exhibit potent anti-platelet activities and cytotoxicity.<br>References Hsieh, P. W., et al.: Bioorg. Med. Chem., 18(21), 7621 (2010);<br></p>

<p>Applications 2-(2-Aminoethyl)-1-methylpyrrolidine is used as an electrochemiluminescence probe within microfluidic chip for ECL detection. 2-(2-Aminoethyl)-1-methylpyrrolidine is also used in chemical microarrays to identify ligands that bind pathogenic cells.<br>References Yin, X._B. et al.: J. Chrom. A, 1091, 158 (2005); Barrett, O.J. et al.: ChemBioChem, 7, 1882 (2006);<br></p>

<p>Applications 2-Chloro-1,1,1-trimethoxyethanen is a reactant in the synthesis of α-chloro-β-aminosulfinyl imidates as chiral building blocks<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Col0paert, F., et. al.: J. Org. Chem., 76, 2204 (2011)<br></p>

<p>Applications 2-Aminobenzophenone is a derivative of Benzophenone (B204980), used in the manufacturing of antihistamines, hypnotics, insecticides. 2-Aminobenzophenone was shown to exhibit modulation activity of GABAA receptor-mediated currents in isolated purkinje neurons.<br>References Kopanitsa, M.V., et al.: Neuropharmacol., 43, 764 (2002); Bringmann, G., et al.: J. Neural. Transmiss. Gen. Sec., 101, 169 (1995);<br></p>

<p>Applications A product from the pyrolysis of phenylalanine.<br>References Kim, D., et al.: Bioorg. Med. Chem. Lett., 15, 2129 (2005), Che, W., et al.: Env. Toxicol. Pharmacol., 24, 11 (2007), Heitman, L., et al.: J. Med. Chem., 51, 4724 (2008),<br></p>

<p>Applications Ammonium Formate-d5 (CAS# 65387-23-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications tert-butyl 2-(4-(bromomethyl)phenyl)acetate (cas# 77292-91-2) is a useful research chemical.<br></p>

<p>Applications 4-PIPERAZIN-1-YL-QUINOLINE DIHYDROCHLORIDE (cas# 1350361-89-5) is a useful research chemical.<br></p>

<p>Applications 2-Cyclopenten-1-one is a chemical reagent used in the synthesis of LY354740, an important glutamate receptor agonist with anticonvulsant and anxiolytic properties. Also used in the synthesis of Armillarivin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Monn, J. et al.: J. Med. Chem., 40, 528 (1997); Schwartz, B. et al.: 15, 1934 (2013);<br></p>

<p>Applications Thymine-alpha,alpha,alpha,6-d4 (CAS# 156054-85-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Propylsulfonamide is used in the preparation of different electron donors in luminogenic luciferins and fluorescent dyes.<br>References Sharma, D., et al.: Org. Lett., 21, 1641-1644 (2019)<br></p>

<p>Applications Bromocyclohexane-d11 is used in the synthetic preparation and regioselective bromination of sp3 C-H bonds by organophotoredox catalysis.<br>References Kee, C.W., et al.: Asian. J. Org. Chem., 3, 536 (2014);<br></p>

<p>Applications 1-Bromo-4-chlorobutane is used as a reagent in the synthesis of a novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Czopek, A., et al.: Bioorg. Med. Chem., 23, 3436 (2015)<br></p>

<p>Applications 1-Bromo-4-chlorobutane-d8 (CAS# 1219803-72-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Cyclopentanecarboxylic Acid is an aliphatic cycloalkyl carboxylic acid used in the preparation of amino acids and other biologically active compounds. Cyclopentanecarboxylic Acid was shown to have plant growth regulating activity.<br>References Dimitrova, T. et al.: Dok. Bulg. Akad. Nauk., 50, 103 (1997); Hasegawa, M. et al.: Tetrahedron, 56, 10153 (2000);<br></p>

<p>Applications Tetracosanoic-9,9,10,10-d4 Acid (CAS# 1219794-61-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Bis(6-methylheptyl) Phthalate-3,4,5,6-d4 (CAS# 2209087-06-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 6-Bromo-2-naphthol is a flavonoid molecule that shows steroid hormone activity and may be useful on anticancer therapy.<br>References Zand, R. et al.: Breast. Can. Res. Treat., 62, 35 (2000);<br></p>

<p>Applications A useful intermediates in the preparation of drugs or pesticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 6-Bromo-2-picoline is a halogenated pyridine derivative used is a building block in the preparation of nitrogen containing heterocyclic compounds.<br>References Long, G.V. et al.: J. Chem. Soc. Dalt. Trans. Inorg. Chem., 21, 3175 (1993); Uenishi, J. et al.: J. Org. Chem., 58, 4382 (1993);<br></p>

<p>Stability Volatile<br>Applications 1-Bromo-2-methylpropane is a halogenated alkane used in various synthetic preparations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Noller, C.R., et al.: Org. Syntheses., 13, (1933); Wang, Z.M., et al.: Lett. Org. Chem., 4, 72 (2007);<br></p>

<p>Applications 1-Bromo-2-methylpropane-3,3,3-d3 (CAS# 344299-42-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Propanal Dipropyl Acetal is a useful synthetic compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Ethyl-5-methylphenol (cas# 1687-61-2) is useful for the characterization of bio-​oil from hardwood and softwood lignin via pyrolysis.<br>References Zadeh, Z. E., et al.: Energies (Basel, Switzerland), 13, 887 (2020)<br></p>

<p>Applications n-Propyl-1,1,2,2-d4 Alcohol (CAS# 70907-80-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Nefiracetam improves post-ischemia evoke-nonconvulsive seizure by altering pro-inflammatory cytokines.<br>References Fu, C. et al: Cell. Phys. Biochem., 37, 2023 (2015);<br></p>

<p>Applications Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.<br>References Sun, L. et al.: Cell, 148, 213 (2012);<br></p>

<p>Applications Cyclopentanone-d8 (CAS# 4477-17-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Propyl-1,1-d2 Alcohol (CAS# 40422-04-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications ethyl 2-(methylamino)-2-oxoacetate (cas# 18522-95-7) is a useful research chemical.<br></p>

<p>Applications 6-Methylpyridine-3-amine, is a heterocyclic building block used in the manufacture of various pharmaceutical compounds. It can be used for the synthesis of 2-aminoquinazoline derivatives, as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators (mGluR5), leading toward a drug candidate for the treatment of l-DOPA induced dyskinesia.<br>References Kubas, H., et al.: Bioorg. Med. Chem. Lett., 23 (16), 4493 (2013);<br></p>

<p>Applications 1-Bromo-3,5-dichlorobenzene-d3 (CAS# 1219803-83-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromo-2,3-dimethyl-benzene is a useful synthetic intermediate. It is used as a reagent to synthesize vaniprevir. It can also be used to synthesize various piperidine derivatives, e.g., 4-arylpiperidines and cinnamoylpiperidine, which are 5-HT2C agonist and PAR1 antagonist, respectively.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, Z., et a;.: J. Org. Chem., 76, 9553 (2011); Conway, R., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012); Planty, B., et al.: Bioorg. Med. Chem. Lett., 20, 1735 (2010)<br></p>

<p>Applications 1-Propanethiol-SD (CAS# 64071-73-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-ethyl-3-methyl-1H-pyrazol-5-amine (cas# 151521-79-8) is a useful research chemical.<br></p>

<p>Applications Cyclopentene-d8 (CAS# 6611-46-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications ethyl 4-aminopentanoate hydrochloride (cas# 119396-97-3) is a useful research chemical.<br></p>

<p>Applications Tetracosanoic-12,12,13,13-d4 Acid (CAS# 1219794-59-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methyl-d3-form-d1-amide (CAS# 110505-55-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-(4-Nitrophenyl)propionic acid is a reagent used in the preparation of α-Methylated analogs of triiodothyroalkanoic acids which have interactions with hepatic thyroid receptors.<br>References Zemker, N., et al.: J. Med. Chem., 35, 548 (1992);<br></p>

<p>Applications N-methoxyacetamide (cas# 5806-90-6) is a useful research chemical.<br></p>

<p>Applications 4,5,6,7-tetrahydro-1H-indazole-6-carboxylic acid (cas# 1354950-72-3) is a useful research chemical.<br></p>

<p>Applications 1,3-Propane-d6-sultone is a useful isotopically labeled compound of 1,3-Propanesultone (P760800)<br></p>

<p>Applications Tetrachlorocyclopropene is a useful compound in organic synthesis.<br>References Belding, Lee, et al.: J. of Org. Chem., 83(12), 6489-6497 (2018); Sanchez Garcia, Jessica J., et al.: Pure and App. Chem., 88(12), 1129-1142; (2016)<br></p>

<p>Applications Phenylacetyl disulfide (cas# 15088-78-5) is a useful research chemical.<br></p>

<p>Applications 1-Bromotetradecane-14,14,14-d3 (CAS# 347840-09-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromotetradecane-1,1,2,2-d4 (CAS# 1219798-81-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Bromo-3'-nitroacetophenone is a reagent used the preparation of arylthiazolidinone derivatives which have BRD4 bromodomain inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, L., et al.: J. Med. Chem., 56, 3833 (2013);<br></p>

<p>Applications Tetronic Acid (cas# 4971-56-6) is a useful research chemical.<br></p>

<p>Applications 3-Bromothioanisole (cas# 33733-73-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications tert-Butyl 6-amino-3,4-dihydroquinoline-1(2H)-carboxylate (cas# 1152923-36-8) is a useful research chemical.<br></p>

<p>Applications 2-Bromothiophene (cas# 1003-09-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (S)-(+)-4-Benzylmorpholin-5-one-3-carboxylic Acid (cas# 106910-79-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Benzyl-2-methyl-3-pyrrolidone (cas# 69079-26-1) is a compound useful in organic synthesis.<br>References Iwanami, S., et al.: J. Med. Chem., 24, 1224 (1981),<br></p>

<p>Applications Intermediate in the production of fentanyl analogs<br>References Dumaitre, B., et al.: J. Med. Chem., 39, 1635 (1996),<br></p>

<p>Applications (2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases.<br>References Gessier, F. et al.: J. Med. Chem., 57, 3358 (2014);<br></p>

<p>Applications 4-(Benzyloxy)aniline Hydrochloride is used as a reagent in the synthesis of a series of amino acid derivatives as novel chromogenic enzyme substrates for the detection of aminopeptidase activity in clinically important microorganisms.<br>References Cellier, M., et al.: Bioorg. Med. Chem., 22, 5249 (2014)<br></p>

<p>Applications 3-Benzyloxybenzaldehyde-alpha-d1 (CAS# 1219805-34-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Coumarin-3-carboxylic acid (cas# 531-81-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Bromo-1,3,4-thiadiazole<br></p>

<p>Applications 1-Bromotridecane-10,10,11,11,12,12,13,13,13-d9 is a useful isotopically labeled compound of 1-Bromotridecane (B688365)<br></p>