Building Blocks

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>1,3,5,7-Tetrabromoadamantane is a molecule that has been synthesized and introduced as a mediator to introduce oxidants. The introduction of the oxidant is mediated by 1,3,5,7-tetrabromoadamantane. This molecule has been shown to be synthesized in two steps from hexamethylenetetramine (HMT) and iodomethane. The synthesis of this molecule can also be achieved by reacting synthons such as tetraphenylmethane with hydrochloric acid. 1,3,5,7-Tetrabromoadamantane is an equivalence mediator because it can mediate a redox reaction in which the oxidizing agent is reduced and the reducing agent is oxidized.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-4-iodoanisole is an electrophilic intermediate that can be synthetically prepared by regioselective halogenations of 4-iodoanisole. It is also a substrate for sequential halogenations with bromine or iodine. The 2-bromo-4-iodoanisole reacts with aluminum to form an aluminate, which can be used as a catalyst in organic synthesis. 2-Bromo-4-iodoanisole has been shown to react with aromatic rings by electrophilically attacking the ring and adding a second bromine atom to the ring, leading to quenching of the molecule and formation of structurally diverse products.</p>

<p>(4-(tert-Butoxy)phenyl)methanamine (BPMT) is a ligand that binds to the alpha-2 receptor and acts as an antagonist. This compound has been shown to be a molecular target for positron emission tomography imaging, which is used in the diagnosis of tumours. BPMT is also used in the treatment of neuropeptide-associated disorders such as Parkinson's disease. The chiral nature of this compound makes it useful for the production of radiopharmaceuticals and other diagnostic agents with different physical properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Methoxyphenyl)ethyl bromide is an adenosine receptor antagonist that can be used in cancer treatment. It has been shown to inhibit the growth of cancer cells by blocking the binding of adenosine to its receptors and inhibiting phosphodiesterase, which is an enzyme that breaks down the key cellular messenger, cyclic AMP (cAMP). 2-(4-Methoxyphenyl)ethyl bromide also inhibits the production of aphanorphine, a morphine analogue that has been shown to stimulate endoplasmic reticulum stress and apoptosis in cancer cells. This compound has been synthesised and tested on animal models with promising results.</p>

<p>Versatile small molecule scaffold</p>

<p>Thiodiglycolic anhydride is a synthetic reagent that is used in the synthesis of erdosteine. It also has been used in the synthesis of other products, such as magnetic particles for imaging and therapeutic uses. Thiodiglycolic anhydride can be used to synthesize erdosteine, which is a substrate for the enzyme hydroxylase and contains a hydroxy group in its structure. The hydroxyl group on erdosteine reacts with thiodiglycolic anhydride to form acrylonitrile, which then reacts with benzyl groups to form benzylthio-esters. These benzylthio-esters are then converted into acid transporters.</p>

<p>(S)-(-)-1-Phenylpropylamine is a compound that can be synthesized by the asymmetric synthesis of 1-phenylethylamine. It is an amine that is used in the production of other compounds and has been shown to be reactive with a number of different compounds. The chemical profile of (S)-(-)-1-Phenylpropylamine consists mainly of aldehydes, amides, amines, and alkylating agents. This chiral molecule can be used for the production of drugs or as a precursor for other chemicals.</p>

<p>Versatile small molecule scaffold</p>

GSK'547 is a small molecule that can interact with the ferroptosis pathway, which is involved in both acute and chronic kidney injury. GSK'547 has been shown to inhibit ischemia reperfusion-induced renal dysfunction by suppressing inflammation and oxidative stress. GSK'547 also inhibits cancer cell proliferation and acts as an anti-inflammatory agent. In addition, GSK'547 has been shown to be beneficial for treating tuberculosis infections and cavity diseases. The mechanism of action of GSK'547 involves inhibiting bacterial cell wall synthesis by binding to the beta-subunit of DNA gyrase. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division.

<p>Chromane-2-carboxylic acid is an amide with a hydroxy group that has inhibitory effects on alkoxyphenols. It has been shown to have the ability to inhibit the growth of cancer cells in mammalian tissue and has been used in synthesizing nitro compounds. Chromane-2-carboxylic acid also inhibits matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix and are associated with tumor invasion and metastasis. This compound also has radical scavenging activities, which may be due to its ability to form hydrogen bonds or intramolecular hydrogen bonds with aromatic hydrocarbons or fatty acids.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Monomethyl glutarate is a monomer for the synthesis of polymers. It has been used in the past as a precursor for the production of polyacrylic acid and its copolymers. Monomethyl glutarate is synthesized by the reaction of hydrochloric acid, high salt, and an expression plasmid containing glutarate dehydrogenase. This compound is also used as a reagent in kinetic studies of fatty acids and glutaric acid. Monomethyl glutarate is an acidic compound with a pKa value of 3.5 at 25°C. It is rapidly hydrolyzed in water to form monomethyl glutarate acid, which has a pKa value of 2.4 at 25°C. Monomethyl glutarate can be ingested orally or applied topically due to its low energy requirements for hydrolysis in water.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Dibenzylurea is an organic molecule that has been used as a model system for the study of chemical reactions. This compound has been shown to have inhibitory properties against pain in animal studies and has been used to treat bowel disease. 1,3-Dibenzylurea can inhibit the inflammatory response by preventing the oxidative carbonylation of proteins. It also inhibits the production of inflammatory cytokines and chemokines in vitro. Nucleophilic attack by amines on the carbonyl group is a possible reaction pathway for this molecule.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Oxotetrahydrofuran-2-carboxylic acid is a solid phase extraction compound that can be used to extract and purify compounds from biological samples. It is synthesized by an asymmetric synthesis of the acetate ester of 5-hydroxytetrahydrofuran-2-carboxylic acid, which is then hydrolyzed to give the desired product. 5-Oxotetrahydrofuran-2-carboxylic acid has been used in cell culture studies as a diagnostic agent for cancer cells. The reactive nature of this molecule allows it to react with chloride ions and fatty acids, which leads to the death of cancer cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Octyldecanoic acid is a fatty acid that is used as a stabilizer in detergent compositions. This stabilizer is also utilizable at high alkali metal concentrations, which makes it suitable for use in hard water conditions. 2-Octyldecanoic acid has a low viscosity at room temperature, and the nature of its hydrocarbon chain leads to increased stability against decomposition when heated or exposed to carbon tetrachloride. It can be synthesized from an aliphatic hydrocarbon, such as octane, to form a macrocyclic ring structure. 2-Octyldecanoic acid also has optical properties that depend on the configuration of the carbon atoms. The molecule has two chiral centers and can exist in four different forms: erythro (E), threo (T), dithreo (D) and meso (M). The optical activity of 2-octyldecanoic acid depends</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>2-Amino-4-hydroxypyridine (2AH) is a synthetic, isomeric compound that has been synthesized in two different forms: 3-bromo-5-hydroxypyridine and hydroxy group. 2AH has been shown to be chemically stable at room temperature and pH levels of less than 7. It also withstands the loss of membrane fluidity induced by amides, such as 3-amino-2-bromopyridine. 2AH can be used to synthesize oxindole derivatives, which are found in natural gas, and piperidines. This chemical can also be used for aminations with pyrrole or 2 amino 4 hydroxypyridine.</p>

(S)-2-Aminobutyramide hydrochloride is a chiral amide compound, which is utilized primarily in scientific research settings. This compound is typically synthesized through the resolution of racemic mixtures or other specialized chemical processes that ensure the purity and stereospecificity required for research purposes.The mode of action of (S)-2-Aminobutyramide hydrochloride revolves around its role as an intermediate in chemical synthesis, serving as a building block for the production of more complex molecules. It has a noteworthy chiral configuration, which makes it an essential component in the formation of enantiomerically pure substances. This aspect is crucial in fields like pharmaceuticals, where stereochemistry can significantly impact biological activity.Its applications extend to various domains such as the synthesis of therapeutic agents, biochemical research, and the development of novel materials. Researchers value it for its ability to contribute to the fine-tuning of molecular assemblies, making it indispensable in studies focused on the interaction and function of chiral molecules. The hydrochloride form aids in its stability and solubility, which are important attributes for laboratory manipulation and experimentation.

<p>4-Acetamidobenzenesulfonyl azide (4ABS) is a low detection reagent that can be used for the determination of 4-acetamidobenzoic acid. It reacts with the amine group in 4-acetamidobenzoic acid to form a sulfonamide intermediate and releases an azide ion. The linear calibration curve was obtained using vibrational spectroscopy and has a detection sensitivity of 0.03 ppm. This method can also be used to determine the functional groups present in dopamine, which have been shown to affect electrochemical impedance spectroscopy measurements.</p>

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<p>Versatile small molecule scaffold</p>

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<p>1-Phenyl-1-butanol (1PB) is a chiral compound that forms hydrogen bonds with itself. It is a colorless liquid that is soluble in organic solvents and has a boiling point of 61 °C. 1PB has been found to inhibit the growth of Pseudomonas aeruginosa by inhibiting fatty acid synthesis, which may be due to its ability to inhibit β-hydroxylase activity. 1PB also inhibits the growth of some bacteria (e.g., Staphylococcus aureus) by blocking the synthesis of fatty acids, which are important for bacterial cell membrane integrity. The hydroxyl group in 1PB helps it form hydrogen bonds with other molecules, including proteins and DNA strands, which makes it useful for chromatographic separation and as an antioxidant in food preservation.</p>

<p>Organic intermediate</p>

<p>4-Bromobenzaldehyde is a chemical compound that belongs to the group of aromatic compounds. It has been shown to have a potent stimulatory effect on locomotor activity in mice, which may be due to its ability to increase levels of epidermal growth factor and gamma-aminobutyric acid in the brain. 4-Bromobenzaldehyde can be synthesized from 2,4-dibromophenol and anhydrous copper chloride in the presence of sodium hydroxide. The reaction mechanism for this synthesis is believed to involve an intermediate enamine form of 4-bromobenzaldehyde, which can then undergo hydrolysis into 2,4-dibromophenol and benzaldehyde. This product is used as a reagent in organic synthesis because it can be used to form esters with trifluoroacetic acid or hydrochloric acid in high yield.</p>

1-Benzofuran-5-carbaldehyde is a synthetic compound that inhibits the enzyme ido1. It has been shown to have potent cytotoxicity, potent inhibition, and neurotrophic properties in a number of cell lines. 1-Benzofuran-5-carbaldehyde also exhibits inhibitory effects on the enzymes hydrolyzing dopamine, which is involved in the synthesis of norepinephrine and epinephrine. The chemical structure of 1-benzofuran-5-carbaldehyde closely resembles that of dopamine and its derivatives, and can be used for the treatment of neurodegenerative diseases such as Parkinson's disease.

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-4-nitropyridine is a pyridine compound that has been identified as an environmental contaminant. It is used to synthesize other compounds, such as 4-(3-bromopyridin-2-yl)morpholine, which is used in the synthesis of acetonitrile. 3-Bromo-4-nitropyridine undergoes nucleophilic substitution reactions with amines, leading to homoconjugation and bond cleavage. This reaction may be followed by nitration to give 3-(3'-nitro)pyridine. 3-Bromo-4-nitropyridine can be converted into its n-oxide form or into the ionic form by treatment with acetonitrile.</p>

<p>2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile is an antibacterial agent that belongs to the group of nitro compounds. It inhibits bacterial growth by blocking the synthesis of proteins and DNA. 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile has been shown to be active against a wide range of bacteria including Gram positive and Gram negative organisms. This compound also exhibits metal ion chelating properties and can be used for the removal of heavy metals from water. The square planar geometry of 2-[(6-Chloro-3,4-(dihydro)-3-(methyl)-2,4-(dioxo)-1</p>

<p>(R)-tert-Butyl 2-methylpiperazine-1-carboxylate is a versatile building block that can be used for the synthesis of complex compounds. The compound is a reagent, speciality chemical, and useful building block in research. It can be used as a reaction component or scaffold in synthesis. (R)-tert-Butyl 2-methylpiperazine-1-carboxylate has been shown to react with nucleophiles such as amines and alcohols to form stable products. This product has high quality and is useful for chemical reactions involving carbonyl groups.</p>

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2-Bromo-5-hydroxypyridine is an aromatic compound that is used in the synthesis of a variety of pharmaceuticals and other organic compounds. It can be synthesized by the Suzuki coupling reaction from 2-bromobenzaldehyde and 5-aminopyridine. 2-Bromo-5-hydroxypyridine has been shown to be a hepatotoxin in humans, with possible carcinogenic activity. It also has cholinergic properties, as well as being able to cause fluorescence when exposed to halogens. The carbon next to the hydroxyl group is a stereocenter, so there are two different configurations for this molecule. The configuration shown above (R) is the more stable form of this molecule due to its electron withdrawing power on the neighboring oxygen atom.

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<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 6-Bromo-4-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. (S)-1-Boc-3-methylpiperazine also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.</p>

<p>2-Hydroxy-3-(1-methylethyl)-butanedioic acid is an organic compound that is a metabolite of the amino acid methionine. It is formed by the oxidation of the methyl group on the 2 position in methionine. The protein subunits are expressed in liver cells and it has been shown to have antioxidant properties. The analytical methods used for this compound include LC-MS/MS, which separates it into its individual isomers. This method can be used to determine the purity of 2-hydroxy-3-(1-methylethyl)-butanedioic acid. The carbonyl group in this molecule makes it susceptible to steric interactions with other molecules, which may lead to it being oxidized or reduced. It has been found that 2-hydroxy-3-(1-methylethyl)-butanedioic acid shows thermophilic and enterocolitic properties.</p>

<p>1,3-Bis(diphenylphosphino)propane is a chelate ligand that forms complexes with a wide range of transition metal ions. It has been shown to be an effective catalyst for the conversion of aryl halides to acid derivatives. The compound has been found to have an excellent stability in aqueous solutions and does not hydrolyze readily in human serum or water. 1,3-Bis(diphenylphosphino)propane is also used as an additive in many industrial processes, such as the production of nylon and polyester fibers.</p>

Boc-Tyr(tBu)-OH is a chemical compound that is part of the class of lactams. It has been shown to have antitumor activity in vitro and in vivo, but it has not yet been tested for its cytotoxicity. This compound is synthesized by solid-phase synthesis and contains a disulfide bond, which may contribute to its cytotoxicity. Boc-Tyr(tBu)-OH has also been shown to have high affinity for the alpha 2A adrenergic receptor subtype and other receptors with an isosteric carbonyl group.

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<p>Boc-His(Trt)-OH is a chemical compound that has been used in the laboratory to study uptake and binding of compounds. It is stable in complex with albumin, which has led to its use as a model system for studying hepatic steatosis. This chemical can be synthesized by solid-phase synthesis with trifluoroacetic acid and polypeptide synthesis. FT-IR spectroscopy has been used to characterize Boc-His(Trt)-OH, revealing its chemical diversity.</p>

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<p>N,N-bis(Hydroxyethyl)-2-aminoethanesulfonic acid sodium salt is a cross-linking agent for polymers. It has been shown to react with dimethylol propionic acid to form a hydroxyl group and a carboxylate. This reaction yields the product of bis(hydroxyethyl) aminosulfonic acid sodium salt. N,N-bis(Hydroxyethyl)-2-aminoethanesulfonic acid sodium salt can be used as a cross-linking agent in the manufacture of biodegradable polymers that are environmentally friendly and biocompatible. The viscosity of the reaction solution increases with an increase in temperature, which is due to the hydrophobic interaction between molecules.</p>

<p>Versatile small molecule scaffold</p>

<p>6-Bromohexanoic acid methyl ester is a linker that can be used in the synthesis of amides. This compound is synthesized by reaction between 2-bromobutyric acid and malonic acid, followed by hydrolysis with sodium hydroxide. 6-Bromohexanoic acid methyl ester is an efficient method for the preparation of amides. It is biologically active and has been shown to have anti-inflammatory properties in biological studies.</p>

<p>Benzophenone-4,4'-dicarboxylic acid is a reactive compound that can form ethylene. It has been shown to be an ultrafast encapsulation material for organic molecules and metal ions. Benzophenone-4,4'-dicarboxylic acid can be used in simulations to study the molecule's surface properties and densities. The linker also plays an important role in determining the diffraction of the molecule. This compound is susceptible to delamination when exposed to silicon surfaces.</p>

<p>4-(Boc-amino)pyridine is a pyridine derivative that exhibits magnetic properties. It can be used to study the luminescence properties of pyridine rings. 4-(Boc-amino)pyridine inhibits cell proliferation and growth by binding to the kinase receptor in the cytoplasm, which blocks phosphorylation of proteins in the cell. This compound inhibits hCT-116 cells, which are human colorectal carcinoma cells, and has shown promising results in xenograft studies. 4-(Boc-amino)pyridine is an anionic molecule that can be used as a starting material for synthesis of other compounds. It was first synthesized by reacting 2-aminopyridine with boron trichloride in acetonitrile.</p>

<p>(2S)-3-Hydroxy-2-phenylpropanoic acid is an unlabelled, naturally occurring compound. It is the citric acid analog of L-phenylalanine. The structure of (2S)-3-Hydroxy-2-phenylpropanoic acid is a skeleton that consists of one hydroxyl group and one carboxylic acid group. The carboxylic acid group has a double bond in the alpha position to the carboxyl carbon, which gives this molecule an acidic character. The chloride ion is also present in this structure. This molecule can be synthesized by a kinetic reaction that involves fatty acids and brugmansia as catalysts. It can also be synthesized through a catalysed reaction using thionyl chloride as a catalyst.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is a synthetic compound that can be used to discriminate between the left and right hands of the body. It has been shown to have a high affinity for the enzyme kinases with an IC50 of 0.5 μM. 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine has been used as a tool in elucidating the mechanism of action of these enzymes by measuring their kinase activity and identifying their substrate specificity. It also has applications in inflammatory diseases as it shifts immune cells from a proinflammatory state to an antiinflammatory state.</p>

<p>2,6-Diaminopyridine is a heterocyclic compound that is used in analytical chemistry as an indicator for the presence of protonated amines. It is prepared by coupling 2,6-diamino-pyridine with 1,3-benzodioxole-5-carboxylic acid. The nitrogen atoms are electron withdrawing groups and form hydrogen bonding interactions with the protonated amine. This type of interaction leads to a phase transition temperature of about 115°C and a high value for electrochemical impedance spectroscopy (EIS) measurements. The reaction mechanism involves the formation of a protonated amine from 2,6-diaminopyridine and 1,3-benzodioxole-5-carboxylic acid followed by proton transfer to yield the corresponding pyridinium salt.</p>

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Please enquire for more information about 6,​7-​Dichloro-​1-​cyclopropyl-​1,​4-​dihydro-​4-​oxo-3-​quinolinecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>4-Chloropyrimidine-2-carbonitrile is an industrial chemical that belongs to the class of heterocycles. It is commonly used in the synthesis of amines, phenoxy compounds, and halides. This compound is widely used in research laboratories as a building block for the synthesis of various organic compounds. 4-Chloropyrimidine-2-carbonitrile is available in enantiopure form, making it suitable for chiral chemistry applications. It contains cyano and ethoxycarbonyl functional groups, which make it versatile for further derivatization. This compound exhibits solid catalyst properties and can be used as a methyl ether or amide precursor. Its emission properties make it useful in fluorescence-based assays and imaging techniques.</p>

FG-2216 is a peptide that activates the G protein-coupled receptor, leading to increased intracellular calcium. FG-2216 is a potent agonist of the GPRC6A receptor and has been shown to inhibit pain perception in animal models. FG-2216 has been shown to have no effect on ion channels and does not affect cellular proliferation or migration. FG-2216 may be useful as a research tool for studying the function of the GPRC6A receptor in animal models.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>