
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3567 products of "Nucleosides"
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3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å
<p>3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å is a monophosphate nucleoside that is used in the synthesis of DNA. It is an antiviral and anticancer drug that inhibits viral replication by competing with natural diphosphate nucleosides. 3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å also has shown to be effective against leukemia cells in vitro and has been shown to inhibit angiogenesis, which may be due to its ability to inhibit the proliferation of endothelial cells.</p>Purity:Min. 95%4-Chloro-5-aminopyrimidine
CAS:<p>4-Chloro-5-aminopyrimidine (4CAP) is an inhibitor of the enzyme purine nucleoside phosphorylase, which is involved in the synthesis of purines and pyrimidines. 4CAP has potent inhibitory activity with a Ki value of 0.06 μM, which is comparable to that of zebularine. 4CAP has also been shown to have antiinflammatory properties in lung tissue. The molecular modeling studies show that 4CAP binds to the hydroxyl group on the enzyme and prevents it from forming a covalent bond with its substrate. This causes a decrease in the rate of reaction time for the enzyme, resulting in decreased production of purines and pyrimidines.</p>Formula:C4H4ClN3Purity:Min. 95%Molecular weight:129.55 g/mol2',3'-Anhydroinosine
CAS:<p>2',3'-Anhydroinosine is an analog of the purine nucleoside inosine, which has been synthesized by catalytic dehalogenation of 2-fluoro-adenosine. The synthesis of this compound is based on a chemical reaction between 2-fluoro-adenosine and sodium hydroxide. This reaction produces 2',3'-anhydroinosine as a byproduct. 2',3'-Anhydroinosine inhibits the enzyme purine nucleoside phosphorylase, which prevents the conversion of inosine to hypoxanthine. This prevents purines from being used for protein synthesis, leading to cell death.</p>Formula:C10H10N4O4Purity:Min. 95%Molecular weight:250.21 g/mol3'-Azido-3'-deoxy-5'-O-tritylthymidine
CAS:<p>An intermediate in the production of Zidovudine, the FDA approved medication for treatment of AIDS.</p>Formula:C29H27N5O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:509.56 g/molantisense
<p>Antisense is a type of experimental therapy that uses a single-stranded RNA molecule to bind to complementary RNA molecules, blocking their function. Antisense rna is often used in gene regulation and chromatin remodeling. It also regulates the transcription of mRNA by binding to the messenger RNA molecule as it leaves the nucleus. The main output of antisense is an increase in the production of one type of protein or a decrease in another. Antisense has been shown to be effective in regulating gene expression and can be used to treat diseases such as cancer and autoimmune disorders.</p>Purity:Min. 95%5'-O-DMT-thymidine-3'-lcaa-CPG
<p>5'-O-DMT-thymidine-3'-lcaa-CPG is a nucleoside, ribonucleoside, and diphosphate that inhibits viral DNA synthesis. It is a novel compound with antiviral properties that has been shown to inhibit the replication of human cytomegalovirus (HCMV) and herpes simplex type 1 virus. 5'-O-DMT-thymidine-3'-lcaa-CPG also functions as an anticancer agent by inhibiting DNA synthesis in tumor cells. This nucleoside analog is phosphoramidite, which can be used for the preparation of modified oligonucleotides. 5'-O-DMT-thymidine-3'-lcaa-CPG has high purity and high quality.</p>Purity:Min. 95%Color and Shape:PowderCytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl)
<p>Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is a nucleoside phosphate activator with antiviral effects. It has been successfully synthesized and shown to be an effective anticancer agent. Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is modified from cytidine, which contains the amino acid L-alanine in place of D-alanine. This modification increases the stability and bioavailability of this molecule. Cytidine, or cytidylate, is a nucleoside phosphate that is widely used in biochemistry as an activator for other nucleosides or as a substrate for enzymes</p>Formula:C25H42N6O13P2S1Purity:Min. 95%Color and Shape:Colorless PowderMolecular weight:728.65 g/mol5'-o-Methyl-dt cep
CAS:<p>5'-o-Methyl-dt cep is a modified phosphoramidite that has been synthesized to provide a novel, highly active anticancer and antiviral agent. It is used as an activator for the synthesis of DNA or RNA in the nucleoside or deoxyribonucleoside pathway. 5'-o-Methyl-dt cep could be used in the treatment of HIV, Hepatitis C, and other viral infections.</p>Formula:C20H33N4O6PPurity:Min. 95%Molecular weight:456.5 g/mol2-(Propylthio)pyrimidine-5-carbaldehyde
CAS:<p>2-(Propylthio)pyrimidine-5-carbaldehyde (2-PSPCA) is a novel, modified ribonucleoside that has been shown to activate the DNA polymerase. 2-PSPCA has been used in the synthesis of deoxyribonucleosides and phosphoramidites for use in the research and development of antiviral agents and anticancer drugs. 2-PSPCA is a monophosphate with an IC50 of 0.6 mM against human leukemia cells.</p>Formula:C8H10N2OSPurity:Min. 95%Molecular weight:182.24 g/mol2',3'-Dideoxyadenosine-5'-monophosphate
CAS:<p>2',3'-Dideoxyadenosine-5'-monophosphate (ddAMP) is an adenosine analog that is a substrate for the enzyme dideoxyribonucleoside kinase. It is activated by phosphorylation to the 5' ends of DNA molecules and inhibits viral replication. ddAMP has been shown to be effective in treating human immunodeficiency virus (HIV) infection, at least in part, by inhibiting the production of p24 antigen levels and reducing the number of CD4+ lymphocytes. The mechanism of action may involve binding to HIV-1 RNA, which prevents it from interacting with cellular dsDNA and inhibits its transcription into DNA.</p>Formula:C10H14N5O5PPurity:Min. 95%Molecular weight:315.22 g/mol8-Azidocyclic adenosine diphosphate ribose
CAS:<p>8-Azidocyclic adenosine diphosphate ribose (8AADPR) is a molecule that is synthesized from ATP and ribose. It has been shown to inhibit the endoplasmic reticulum Ca2+-ATPase, which transports calcium ions out of the cell, leading to increased concentrations of calcium ions in the cytosol. 8AADPR also inhibits mitochondrial ATPase, which leads to an accumulation of ADP-ribose within mitochondria. This accumulation leads to the inhibition of protein synthesis within mitochondria and an activation of ryanodine receptors. There are no known adverse effects associated with 8AADPR at this time, but it should be used with caution due to its potential effects on cardiac function.</p>Formula:C15H20N8O13P2Purity:Min. 95%Molecular weight:582.31 g/molAMP PNP tetralithium salt
CAS:<p>Non-hydrolyzable AMP analog</p>Formula:C10H13Li4N6O12P3Purity:Min. 95%Molecular weight:529.93 g/mol5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide
CAS:<p>5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.</p>Formula:C15H20N4O8Purity:Min. 95%Molecular weight:384.34 g/mol5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil
<p>5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a phosphoramidite, activator, and synthetic nucleoside that has been modified to contain fluorine atoms. 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is an antiviral agent that was developed for the treatment of HIV/AIDS and cancer. It inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This drug also has anticancer properties because it inhibits the synthesis of DNA in tumor cells and activates apoptosis, causing cell death.</p>Purity:Min. 95%Linoleoyl coenzyme A
CAS:<p>Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.</p>Formula:C39H66N7O17P3SPurity:Min. 95%Molecular weight:1,029.97 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite
CAS:<p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite is a novel nucleoside monophosphate that has been modified with fluorine at the 2' position and a deoxyribose sugar. 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite may be useful for antiviral treatment, as it can inhibit human immunodeficiency virus type 1 (HIV1) replication in vitro by inhibiting HIV1 reverse transcriptase. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis or promote apoptosis.</p>Formula:C39H46FN4O8PPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:748.8 g/mol1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil
<p>1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil is a synthetic nucleoside that is activated by phosphorylation. This nucleoside is an antiviral and anticancer agent, and has been shown to be active against HIV, cytomegalovirus, herpes simplex virus type 1, and lymphocytic leukemia cells. It has also been shown to have anti-inflammatory properties. The compound is a monophosphate and diphosphate, which are more potent than the corresponding ribonucleosides. 1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil has CAS number 26582, high purity, high quality.</p>Formula:C28H23FN2O4Purity:Min. 95%Molecular weight:470.49 g/mol2’,3’-Dideoxy-5-fluorocytidine
CAS:<p>2’,3’-Dideoxy-5-fluorocytidine is a nucleoside analog that inhibits the growth of tumor cells in animals. It has been shown to inhibit the replication of hepatitis B virus and HIV without affecting normal cell division. 2′,3′-Dideoxy-5-fluorocytidine also has potent antitumor activity against human hematopoietic cells and induces apoptosis.</p>Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/mol2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS:<p>2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog. The fluorine substitution and sugar modification allow it to mimic natural nucleosides but disrupt DNA or RNA synthesis when incorporated. The fluorine makes the molecule more chemically stable and can influence how enzymes interact with it. Like other nucleoside analogs, it has the potential to act as a chain terminator or inhibit key enzymes like polymerases or reverse transcriptases.</p>Formula:C10H13FN6O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:284.25 g/molAcetoacetyl coenzyme A trisodium salt tetrahydrate
CAS:<p>Acetoacetyl coenzyme A trisodium salt tetrahydrate is a novel antiviral agent that inhibits the synthesis of viral DNA and RNA. Acetoacetyl CoA has been shown to inhibit the replication of HIV, HSV-1 and HSV-2, influenza virus, and cytomegalovirus (CMV). The mechanism of action is not yet known but may be related to its ability to activate cellular DNA polymerase β. Acetoacetyl CoA also has a high purity and quality, as well as being modified for use in phosphoramidites.</p>Formula:C25H37N7Na3O18P3S·4H2OPurity:Min. 96 Area-%Color and Shape:PowderMolecular weight:989.62 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt
<p>9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt is a modified nucleoside phosphoramidite. It is used as an antiviral and anticancer agent, as well as an activator in DNA synthesis. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt has been shown to be active against HIV, herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, influenza A virus, and human papillomavirus types 16 and 18.</p>Formula:C39H39FN5O10·C6H16NPurity:Min. 95%Molecular weight:858.97 g/mol2'-13CCytidine
CAS:<p>2'-13CCytidine is a cytidine nucleoside that inhibits the synthesis of RNA and DNA in cells. It is an analog of cytarabine, which is a pyrimidine nucleoside and an antineoplastic agent. 2'-13CCytidine has been shown to be effective as an antiviral agent against HIV-1 and HSV-2, as well as an immunosuppressant for the treatment of autoimmune diseases such as rheumatoid arthritis. This drug is used in chemotherapy to inhibit cell division in leukemia.</p>Formula:CC8H13N3O5Purity:Min. 95%Molecular weight:244.21 g/mol2-Amino-2'-deoxyadenosine 5'-triphosphate
CAS:<p>2-Amino-2'-deoxyadenosine 5'-triphosphate (2ADP) is a nucleotide that is involved in the synthesis of DNA. It is an important part of the process of DNA replication, as it provides the necessary energy to drive reactions that synthesize new DNA strands. It also has anti-viral properties and can be used as a molecular probe to detect acid. 2ADP is detectable with most common detection methods, such as UV/visible absorbance spectroscopy, fluorescence spectroscopy, and chemiluminescence. It is one of the three triphosphates found in cells and can be used to polymerize RNA by adding ribose phosphate groups to the sugar molecule in RNA. This reaction requires ATP, which produces AMP, ADP, and 2ADP.</p>Formula:C10H17N6O12P3Purity:Min. 95%Molecular weight:506.2 g/mol2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)
CAS:<p>Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C56H61N8O12PPurity:Min. 95%Molecular weight:1,069.1 g/mol7H-Pyrrolo[2,3d]pyrimidine
CAS:<p>7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has a</p>Formula:C6H5N3Purity:Min. 95%Molecular weight:119.12 g/mol5'-O-Acetyl-2',3'-dideoxyinosine
CAS:<p>5'-O-Acetyl-2',3'-dideoxyinosine is a nucleoside analogue that inhibits viral replication. It is a potent activator of the immune system and has been shown to be effective against cancer cells. 5'-O-Acetyl-2',3'-dideoxyinosine was originally synthesized as an antiviral agent, but it was found to be ineffective in this function. The drug binds to the ribonucleotide reductase enzyme, which converts ribonucleotides into deoxyribonucleotides and is essential for the production of DNA. The drug blocks the conversion of ribonucleotides into deoxyribonucleotides, preventing DNA synthesis and replication. This drug has also been shown to have anticancer activity by inhibiting DNA synthesis and cell division.</p>Formula:C12H14N4O4Purity:Min. 95%Molecular weight:278.26 g/molN6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine
CAS:<p>N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.</p>Formula:C24H31IN4O4SiPurity:Min. 95%Molecular weight:594.52 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate
CAS:<p>5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate (AICAR) is a bifunctional agent that has been shown to stimulate the activity of adenylosuccinate synthetase, an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to adenosine triphosphate (ATP). AICAR is also a substrate for adenylosuccinate synthetase. The use of AICAR as a pharmacological agent has been associated with increased levels of nucleotides in cells and tissues. This may be due to the activation of AMPK, which stimulates ATP production by breaking down ATP through oxidative phosphorylation.<br>AICAR can be detected using chromatographic techniques, such as high performance liquid chromatography or thin layer chromatography.</p>Formula:C9H17N4O14P3Purity:Min. 95%Molecular weight:498.17 g/mol2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt
CAS:<p>2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt (2'-dO-5HmcMP) is a nucleoside analogue that inhibits the activity of reverse transcriptase, an enzyme required for replication of HIV. This compound is phosphorylated in vivo to 2'-dO-5HmcMP monophosphate, which then competitively inhibits the binding of dNTPs to the enzyme and prevents DNA synthesis. 2'-dO-5HmcMP also has anticancer activity and has been shown to inhibit the proliferation of cells in vitro.<br>2'-dO-5HmcMP has no significant toxicity to humans or other mammals.</p>Purity:Min. 95%1-(2-Deoxy- 2, 2- difluoro- b- D- xylofuranosyl)cytosine
CAS:<p>1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine is a nucleoside (a compound consisting of a nucleotide base linked to a sugar). It is a modified form of cytosine that has been phosphorylated at the 2’ position. 1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine has antiviral and anticancer activity through its ability to inhibit viral DNA synthesis and activate the immune system. This drug also has antitumor activity due to its ability to inhibit the tumor growth factor beta (TGFB). 1-(2-Deoxy-2,2-difluoro-beta-D -xylofuranosyl)cytosine can be used in cancer treatment as an anticancer agent.</p>Formula:C9H11F2N3O4Purity:Min. 95%Molecular weight:263.2 g/mol2-Methylthio-6-chloro-9-methylpurine
CAS:<p>2-Methylthio-6-chloro-9-methylpurine is an activator that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA and RNA. 2-Methylthio-6-chloro-9-methylpurine has been shown to inhibit viral replication and may be used as a antiviral agent. This compound has novel properties and is a potential anticancer drug due to its ability to inhibit the growth of tumor cells.</p>Formula:C7H7CIN4SPurity:Min. 95%Molecular weight:318.14 g/mol3'-Deoxy-3'-fluoro-5'-O-tritylthymidine
CAS:<p>3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.</p>Formula:C29H27FN2O4Purity:Min. 95%Molecular weight:486.53 g/mol2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt
CAS:<p>2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt (2'OMeEtGTP) is an antiviral agent that is used as a component of an antiviral drug. It inhibits the viral enzyme DNA polymerase, which prevents viral replication and transcription. This compound has been shown to have anticancer properties in vitro and in vivo in rat models. 2'OMeEtGTP is synthesized by reacting the nucleoside phosphoramidite 2'OMeEtGTP with triethylammonium phosphate (TEAP).</p>Purity:Min. 95%N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine
<p>N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is a modified nucleoside that can be used in the synthesis of DNA, RNA, and other nucleic acids. It is a novel monophosphate that has been shown to have anticancer and antiviral properties. N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is synthesized by reacting 2,4,6 trichlorobenzoyl chloride with morpholine and silylation. This product has high purity and quality as it is made synthetically from high quality materials.</p>Purity:Min. 95%4'-Azidothymidine 5-triphosphate
CAS:<p>4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.</p>Formula:C10H16N5O14P3Purity:Min. 95%Molecular weight:523.18 g/mol5'-O-DMT-2'-O-hexylamino-5-methyluridine
CAS:<p>5'-O-DMT-2'-O-hexylamino-5-methyluridine is a nucleoside analog that is used in cancer treatment. It is synthesized by the chemical modification of uridine, which is converted to 5'-O-DMT-2'-O-hexylamino-5-methyluridine by reacting with 2',3'-dideoxyadenosine and 5,6,7,8,-tetrahydroisoquinoline. The monophosphate form of 5'-O-DMT-2'-O-hexylamino-5-methyluridine may be converted to the diphosphate form by phosphorylation with ATP. In addition to its anticancer effects, 5'-O-DMT-2'-O-hexylamino-5-methyluridine has antiviral and antiretroviral effects due to its inhibition of viral DNA synthesis.</p>Formula:C37H45N3O8Purity:Min. 95%Molecular weight:659.79 g/mol9-(2-C-Methyl-b-D-ribofuranosyl)purine
CAS:<p>9-(2-C-Methyl-b-D-ribofuranosyl)purine is a nucleoside that is used as an activator in the synthesis of phosphoramidites. 9-(2-C-Methyl-b-D-ribofuranosyl)purine has antiviral and anticancer properties, and it also inhibits the growth of bacteria. This nucleoside is synthesized from 2,4,6-trichlorophenylisocyanate and 5'-O-(4,4'-dimethoxytrityl)-beta-D-ribofuranose. The chemical name for 9-(2-C methyl b D ribofuranosyl)purine is 690269 - 86 - 4.</p>Formula:C11H14N4O4Purity:Min. 95%Molecular weight:266.25 g/mol(5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite
CAS:<p>(5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite is a nucleoside that is used in the synthesis of DNA. It is an analog of adenosine and has antiviral and anticancer properties. It also has been shown to inhibit the growth of certain types of cancer cells by inhibiting the production of deoxyribonucleosides. (5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite can be used as a monophosphate or as a diphosphate for incorporation into DNA strands. This compound belongs to the group of modified nucleosides, which are synthetically produced compounds that are different from naturally occurring nucleosides found in DNA. (5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite is purified and has high purity when purchased from us.</p>Formula:C47H50N7O7PPurity:Min. 95%Molecular weight:855.92 g/molFluorescein alkynylamino-ATP - 1.0 mM solution
CAS:<p>Fluorescein alkynylamino-ATP is a fluorescent nucleotide analog that is used in molecular biology for the detection of DNA. It is labeled with tetramethylrhodamine, which can be detected using a fluorescence microscope. Fluorescein alkynylamino-ATP is a postsynthetic modification to DNA, which means it is added after the DNA has been synthesized. This molecule can be incorporated into the growing strand by either monoaddition or polymerase extension. Fluorescein alkynylamino-ATP binds to the 3' end of a primer during polymerase chain reaction (PCR) and can be detected using electrophoresis and sequence analysis.</p>Formula:C41H41N6O20P3Purity:Min. 95%Molecular weight:1,030.71 g/mol5,6-Dihydro-5'-O-DMT-thymidine 3'-CE phosphoramidite
<p>This is a synthetic DNA analogue that is used in the synthesis of oligonucleotides. It is a phosphoramidite in which the 5,6-dihydro-5'-O-DMT group has been modified to allow for incorporation into DNA and RNA. This compound has antiviral and anticancer activities.</p>Formula:C40H51N4O8PPurity:Min. 95%Molecular weight:746.83 g/mol3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine
<p>3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.</p>Formula:C24H20N8O4Purity:Min. 95%Molecular weight:484.47 g/molTroxacitabine
CAS:<p>Troxacitabine is a nucleoside analog that inhibits DNA synthesis by selectively blocking the function of DNA polymerase. It has been shown to have potent antitumor activity in mouse tumor models and in a human breast cancer xenograft model. Troxacitabine has also been shown to inhibit the proliferation of renal cell cancer cells and induce apoptosis in these cells, as well as reduce the viability of cancer cells from other tumor types. Troxacitabine has also been shown to have an effect on body mass index and hematologic response, although it is not currently approved for use in humans.</p>Formula:C8H11N3O4Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:213.19 g/mol1-(3'-O-Nosyl-5'-O-trityl-2'-deoxy-b-D-lyxofuranosyl)thymine
CAS:<p>Ribonucleosides are nucleosides that contain ribose as their pentose sugar. Ribonuclesides are synthetic, modified ribonucleosides that have been modified to include a 2'-deoxy-b-D-lyxofuranosyl group at the 3' position. Ribonuclesides activate antiviral activity by inhibiting viral DNA synthesis and protein synthesis. They also inhibit cancer cell proliferation by inhibiting DNA synthesis and RNA synthesis.</p>Formula:C35H31N3O9SPurity:Min. 95%Molecular weight:669.7 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate
<p>2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate is a novel synthetic nucleoside analog with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine has been shown to be effective against human leukemia cells in vitro and in vivo.</p>Formula:C10H17ClN5O12P3Purity:Min. 95%Molecular weight:527.64 g/molN4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate
<p>N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate is a synthetic nucleoside that has antiviral activity. It is a modification of the natural nucleoside cytidine, where the 4th position of the ribose ring is substituted with an acetyl group and the 2' position of the sugar moiety is substituted with a 2' deoxyribofuranosyl group. N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate inhibits viral replication by inhibiting viral RNA synthesis. Its antiviral properties may be due to its ability to inhibit DNA polymerase and reverse transcriptase, which are enzymes that synthesize DNA from RNA.</p>Purity:Min. 95%3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine
CAS:<p>3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine is a novel antiviral agent that is synthesized as a deoxyribonucleoside monophosphate. It inhibits viral DNA polymerase and RNA synthesis by competitively inhibiting the incorporation of diphosphates into viral DNA. It has been shown to be active against herpes simplex virus type 1 and 2, vaccinia virus, influenza A virus, and Sindbis virus. 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine has also been shown to have anticancer properties in vitro and in vivo.</p>Formula:C21H23N5O6Purity:Min. 95%Molecular weight:441.44 g/mol2-Deoxycytidine 3',5'-diphosphate
CAS:<p>2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.</p>Formula:C9H15N3O10P2Purity:Min. 95%Molecular weight:387.18 g/mol1-(b-D-Arabinofuranosyl)-5-iodouracil
CAS:<p>1-(b-D-Arabinofuranosyl)-5-iodouracil is a synthetic nucleoside that has antiviral and anticancer properties. It is a monophosphate nucleotide that inhibits viral RNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This inhibitor also blocks DNA synthesis by preventing the incorporation of b-D-arabinofuranosyl monophosphate into DNA. 1-(b-D-Arabinofuranosyl)-5-iodouracil has been shown to be effective in treating various types of cancer, including breast, lung, and prostate cancers. It also exhibits antitumor activity against certain human leukemia cells.</p>Formula:C9H11IN2O6Purity:Min. 95%Molecular weight:370.1 g/mol1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS:<p>Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.</p>Formula:C29H53N3O4Si3Purity:Min. 95%Molecular weight:592.01 g/molAdenosine 5'-triphosphate trisodium salt
CAS:<p>ATP is an important molecule in the body that is involved in a number of cellular processes, including energy production and transmission. It has been shown to be tumorigenic and is found at high levels in plasma membranes and muscle cells. ATP binds to the adenylate cyclase enzyme in the cell membrane and stimulates its activity, which increases intracellular levels of cyclic AMP (cAMP). Cyclic AMP activates protein kinase A, which phosphorylates proteins, leading to a cascade of reactions that result in cellular changes. ATP also has pharmacological effects on the plasma membrane by increasing its permeability to certain ions such as potassium ions. This leads to an increase in the rate of depolarization of the cell membrane, which causes an influx of calcium ions into the cell.</p>Formula:C10H15N5O13P3Na3Purity:Min. 95%Molecular weight:575.14 g/mol3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine
CAS:<p>3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.</p>Formula:C23H17Cl2FN2O7Purity:Min. 95%Molecular weight:523.29 g/molN6-Benzyladenosine 5'-triphosphate triethylammonium salt
CAS:<p>N6-Benzyladenosine 5'-triphosphate triethylammonium salt is a hydrogen bond donor that is not naturally occurring. It has been shown to be a potent and selective analog of ATP with high specificity for cGMP-dependent protein kinase. This drug has been used to study the function of serotonin receptors, tyrosine kinases, and epidermal growth factor receptors. N6-Benzyladenosine 5'-triphosphate triethylammonium salt has also been shown to increase the sensitivity of cells to epidermal growth factor and to inhibit the reuptake of serotonin.END></p>Formula:C19H26N5O11P3·C18H48N3Purity:Min. 95%Molecular weight:899.95 g/mol3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:<p>3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is an inhibitor of the enzyme kinase. The active form of 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution inhibits human immunodeficiency virus (HIV) reverse transcriptase, preventing the synthesis of viral DNA. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to inhibit cancer cell growth in culture and to inhibit cancer cell proliferation in mice. This compound is also active against cancer cells that are resistant to other anti-cancer drugs. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is phosphorylated by cellular kinases, which may be</p>Formula:C10H16N5O13P3·xLiPurity:Min. 95%Color and Shape:Colorless Clear LiquidMolecular weight:507.18 g/mol3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine
<p>3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is an antiviral agent that inhibits the production of virus particles by inhibiting DNA and RNA synthesis. It is a modified nucleoside analog that has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. This drug has also been shown to be effective against leukemia and lymphoma cells, as well as other types of cancer cells. 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is used for the treatment of AIDS, hepatitis B, hepatitis C, herpes zoster (shingles), and other diseases caused by viruses. It can be administered orally or intravenously.</p>Formula:C28H33FN2O6SiPurity:Min. 95%Molecular weight:540.66 g/mol4-Amino-6-hydroxy-2-methylpyrimidine
CAS:<p>4-Amino-6-hydroxy-2-methylpyrimidine (4AMMP) is a heterocyclic compound that belongs to the group of pyrimidines. It has been shown to react with morpholine and acrylic acid in an oxidation sequence. The reaction proceeds through an elimination, forming formaldehyde, which condenses with hydrolyzed piperazine to give the final product. 4AMMP can also be alkylated with a variety of reagents such as methyl iodide or dimethyl sulfate.</p>Formula:C5H7N3OPurity:Min. 95%Color and Shape:PowderMolecular weight:125.13 g/mol2-Methylthioadenosine-5'-triphosphate
CAS:<p>2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.</p>Formula:C11H18N5O13P3SPurity:Min. 95%Molecular weight:553.27 g/mol3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine
CAS:<p>3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine is a novel nucleoside phosphoramidite. The 3'-azido group can be used to protect the 5' hydroxyl group during phosphitylation, which is essential for the synthesis of modified nucleosides. The 2',3'-dideoxy configuration ensures that the sugar moiety is not cleaved from the base during polymerization, and that no undesired side reactions occur during purification. This product has been shown to have antiviral and anticancer activity in vitro.</p>Formula:C20H32N8O4SiPurity:Min. 95%Molecular weight:476.61 g/mol5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
<p>5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral drug that has been shown to inhibit the synthesis of viral RNA by inhibiting the activity of DNA polymerase. It is a novel antiviral drug with high purity and can be used for cancer treatment as well. 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also has a novel mechanism of action, which is different from other antiviral drugs such as ribonucleosides or deoxyribonucleosides. This compound is used in the synthesis of phosphoramidites for oligonucleotide synthesis.</p>Formula:C17H27IN4O3SiPurity:Min. 95%Molecular weight:490.41 g/mol8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:<p>8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is synthesized by reacting 8-aminoimidazo[2,1-b]thiazole 1,3(2H)-dione (AITD) with N6,N8-diisopropyl dATP to form the aminothiazole phosphate intermediate. This intermediate is then reacted with 5'-O-(4,4'-dimethoxytrityl)-2',3',5' triphosphate (DMTrP) to produce the desired product. The synthesis of 8AAODMTAP has been shown to be more efficient than other synthesized nucleosides due to its high purity and lack of impurities.</p>Formula:C46H59N10O6PPurity:Min. 95%Molecular weight:879 g/mol2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt
CAS:<p>2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt (ddI-TP) is a nucleoside analog that inhibits HIV replication by competing with natural nucleosides for binding to HIV reverse transcriptase. ddI-TP acts as an inhibitor of human mitochondrial DNA polymerase γ, and blocks the synthesis of fatty acids in mouse cells. It is also able to inhibit signal pathways involving protein kinases and phosphatases. ddI-TP has been shown to be effective against hiv infection in mice. This drug can be used in the treatment of hiv infection, as well as in the prevention of its transmission from mother to child during pregnancy and breastfeeding.</p>Formula:C10H15N4O12P3Purity:Min. 95%Molecular weight:476.17 g/mol2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate)
CAS:<p>2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) (2,3'-ddGTP) is a nucleoside that is synthesized using phosphoramidite chemistry. It has antiviral and anticancer activity, as well as the ability to activate cellular transcription. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can be used in the synthesis of modified nucleosides or in the synthesis of novel nucleosides. The compound was found to inhibit DNA replication by binding to the enzyme ribonucleotide reductase. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can also be used for DNA sequencing and as a cytotoxic agent in cancer chemotherapy.</p>Formula:C10H16N5O11P3SPurity:Min. 95%Molecular weight:507.25 g/mol8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine
CAS:<p>8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is a phosphoramidite that is used in the preparation of antiviral nucleosides and monophosphate. It has been shown to have anticancer activity. 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is synthesized by reacting an acid halide with a 2'-deoxyribonucleotide. This reaction produces a 2'-bromo adenosine derivative, which is then reacted with dimethylamine to produce the desired product. The synthesis of 8-bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine can be performed on a large scale using an automated process.</p>Formula:C13H17BrN6O3Purity:Min. 95%Molecular weight:385.22 g/mol2'-Deoxy-2'-fluoroguanosine-5'-monophosphate
CAS:<p>2'-Deoxy-2'-fluoroguanosine-5'-monophosphate is a phosphoramidite monoester with a diphosphate group that has been synthetically modified to provide antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits the proliferation of tumor cells by interfering with DNA replication. The compound is also used as a precursor for the synthesis of 2'-deoxy-2'-fluoroguanosine, which has potent anti-HIV activity.</p>Formula:C10H13FN5O7PPurity:Min. 95%Molecular weight:365.21 g/mol2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine
CAS:<p>2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine is a monophosphate nucleoside analog that has antiviral activity against the Herpes virus. It is a cytosine analog that is incorporated into DNA and inhibits viral replication. 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine has also been shown to have anticancer properties and high purity. This compound is synthesized by the reaction of 2'-deoxycytidine and 4-(2,2,2,-trimethylpropionyl)-1,3-butanediol with O-(7-azabenzotriazol-1-yl) N,N,N',N' tetramethyluronium hexafluorophosphate (HATU) in anhydrous pyridine. The CAS number for this compound is 10089862.</p>Formula:C34H37N3O7Purity:Min. 95%Molecular weight:599.69 g/molXTT, sodium salt
CAS:<p>XTT is a tetrazolium compound that can be used to measure the activity of enzymes. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. XTT can also be used as an antibacterial agent against C. glabrata and as an anthelmintic drug against tapeworms. This compound is not active against other bacteria, such as E. coli or S. aureus, because they are resistant to oxidative injury and have high levels of ABCG2 (ATP-binding cassette G2), which prevents intracellular accumulation of XTT.</p>Formula:C22H16N7NaO13S2Molecular weight:673.53 g/molRef: 3D-X-5000
1gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire2500mgTo inquire-Unit-ggTo inquire2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
CAS:<p>2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine is a novel modified nucleoside with antiviral activity. It has been shown to inhibit the replication of the influenza A virus in cell culture and animal models. 2′Amino-6′chloro 9-(2′deoxy 3′,5′di O′benzoyl 2′fluoro b D arabinofuranosyl)purine is an analog of adenosine that has shown anticancer activity in vitro and in vivo. It inhibits DNA synthesis by inhibiting deoxyribonucleotide synthesis and ribonucleotide synthesis. This drug also inhibits cell proliferation and induces apoptosis.</p>Formula:C24H19ClFN5O5Purity:Min. 95%Molecular weight:511.89 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:<p>3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that is used in the synthesis of oligonucleotides. It is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to have high purity and quality. The synthesis of this compound involves the use of a novel activator, which is also available for purchase from this website. This nucleoside has been modified with tert-butyldimethylsilyl groups at the 3' and 5' positions of the ribose moiety, which prevents the hydrolysis of the phosphate ester bond by alkaline phosphatase enzymes, thus allowing for sequence determination.</p>Purity:Min. 95%2'-Deoxy-5-(trifluoromethyl)cytidine
CAS:<p>2'-Deoxy-5-(trifluoromethyl)cytidine is a synthetic nucleoside analogue that inhibits the cytidine deaminase enzyme. It is used in the treatment of some types of leukemia and other cancers. The compound, which has a trifluoromethyl group on the 2' position, binds to the active site of cytidine deaminase and prevents it from functioning. This leads to an accumulation of thymidylate, which is required for DNA synthesis. The tumor tissue also contains high concentrations of this drug and its metabolites, making it more effective against cancer cells than normal cells. 2'-Deoxy-5-(trifluoromethyl)cytidine has been shown to inhibit anabolism in tumor tissue in the presence of high concentrations of phosphorylases, which are enzymes that catalyze reactions that break down carbohydrates and proteins into smaller molecules such as glucose or amino acids.</p>Formula:C10H12F3N3O4Purity:Min. 95%Molecular weight:295.22 g/mol1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione
CAS:<p>1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is an organic semiconductor material. It is a dielectric with a high transition temperature and good electrical conductivity. This compound is a metal silicide with a low resistivity and high electron mobility. It can be used as an active layer in thin film transistors or as a field effect transistor channel material. 1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione has been shown to have good chemical stability and thermal stability in air at temperatures up to 400°C.</p>Purity:Min. 95%8-Chloroadenosine 3',5'-cyclic monophosphate
CAS:<p>8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.</p>Formula:C10H11ClN5O6PPurity:Min. 95%Color and Shape:White PowderMolecular weight:363.65 g/molAdenylosuccinic acid
CAS:<p>Adenylosuccinic acid is an organic acid that is synthesized through the deamination of adenosine monophosphate. It is used in transfection experiments to inhibit polymerase chain reaction (PCR) and reverse transcriptase. Adenylosuccinic acid inhibits DNA synthesis by targeting enzymes such as the ribonucleotide reductase and the DNA polymerase β-subunit. Adenylosuccinic acid also inhibits protein synthesis, which may be due to its ability to inhibit energy metabolism, leading to cellular death. This drug has been shown to have a wide range of pharmacological effects, including anti-inflammatory, analgesic, and antifungal activity.</p>Formula:C14H18N5O11PPurity:Min. 95%Color and Shape:PowderMolecular weight:463.29 g/molChemical phosphorylating reagent (cpr)
CAS:<p>Chemical phosphorylating reagent (CPR) is a powerful tool for the study of kinases, which are enzymes that regulate cellular processes such as cell division and apoptosis. CPR has been shown to be effective in inhibiting the activity of certain kinases that are involved in tumor growth and progression. It has also been used as an anticancer agent, inducing apoptosis in cancer cells. CPR is an analog of toxaphene and labetalol, two compounds with known kinase inhibitor activity. This reagent has been tested on human urine samples and Chinese hamster ovary cells, demonstrating its potential as a valuable research tool for studying kinase signaling pathways and developing new cancer therapies.</p>Formula:C5H10O5Purity:Min. 95%Molecular weight:150.13 g/molb-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate
CAS:<p>b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate is a novel anticancer compound that has been shown to inhibit the growth of cancer cells in vitro. The mechanism of action of b-NADP+ is still unknown, but it may involve the inhibition of ribonucleoside reductase and deoxyribonucleoside reductase. It also inhibits viral DNA synthesis, which can be an effective antiviral drug. b-NADP+ is a nucleotide analogue that is synthesized from diphosphate and monophosphate forms, which are activated by phosphoramidites.</p>Formula:C21H28N7O17P3•K•(H2O)2Purity:Min. 95%Molecular weight:818.5 g/mol2'-TFA-NH-dC
CAS:<p>2'-TFA-NH-dC is a novel nucleoside analogue that has been modified to have antiviral and anticancer properties. The chemical structure of 2'-TFA-NH-dC closely resembles dC, which is a natural DNA nucleotide, but with the addition of an extra fluorine atom at the 2' position. This modification increases the potency of 2'-TFA-NH-dC by making it more difficult for enzymes in cells to break down the drug. The compound can be used as a monophosphate or diphosphate, and is synthesized from 2'-deoxyadenosine 5'-phosphoramidite and 1,2,4-triazole in water.</p>Formula:C11H13F3N4O5Purity:Min. 95%Molecular weight:338.24 g/molAdenosine 5'-(tetrahydrogen triphosphate)
CAS:<p>Adenosine is a nucleoside consisting of adenine and ribose. It is used in biochemical analysis to quantify the cytosolic Ca2+ concentration, which is an important cellular signal that regulates many cellular processes. Adenosine stimulates the uptake of Ca2+ by binding to the monophosphate-activated protein (AMPAR), which results in the opening of voltage-gated calcium channels. These channels allow Ca2+ to enter the cell, increasing its intracellular concentration. Adenosine also has been shown to stimulate muscle contraction through increased release of Ca2+. This drug also possesses inhibitory effects on synaptic transmission and may have anti-inflammatory properties due to its ability to inhibit proteolytic enzymes in muscle cells.</p>Formula:C10H14MgN5O13P3Purity:Min. 95%Molecular weight:529.47 g/molo-Methoxytopolin riboside
CAS:<p>o-Methoxytopolin Riboside is a novel phosphoramidite that can be used for the synthesis of ribonucleotides and deoxyribonucleosides. This product has antiviral and anticancer properties, as well as the ability to inhibit tumor growth by inducing apoptosis in cancer cells. It is synthesized from the natural compound o-methoxytyrosine by the addition of a phosphate group to the 3-position. The phosphate group is then modified to produce monophosphate or diphosphate forms. OMTPR has been shown to have anti-inflammatory properties and has been found to reduce inflammation in mice with colitis.</p>Formula:C18H21N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:387.39 g/mol3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine
CAS:<p>3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is a novel synthetic nucleoside. It is an intermediate in the synthesis of phosphoramidites and has been used in the synthesis of oligonucleotides and DNA. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine can also be used as antiviral and anticancer agents. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is soluble in water, ethanol, and chloroform at a concentration of 1 g/L. The purity of this product is greater than 98%.</p>Formula:C21H39BrN2O5Si2Purity:Min. 95%Molecular weight:535.62 g/mol2,2-Crylo-5-methyluridine
<p>2,2-Crylo-5-methyluridine is a synthetic diphosphate nucleotide that has been shown to be an activator of DNA synthesis. It is used in the synthesis of oligonucleotides and as a monophosphate for the synthesis of 2'-O-methyl ribonucleosides. 2,2-Crylo-5-methyluridine has been shown to have anticancer activity, which may be due to its ability to inhibit tumor proliferation or induce apoptosis.</p>Purity:Min. 95%Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt
CAS:<p>Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a neurotrophic factor that has been shown to have neuroprotective properties in different animal models of Parkinson's disease. It has been shown to promote the synthesis of dopamine, glutamate, and other neurotransmitters in dopaminergic neurons. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt also promotes protein production by stimulating the synthesis of intracellular proteins such as cytosolic Ca2+ and IGF-I. This drug may be effective in pharmacological treatment for Parkinson's disease. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a potent inhibitor of phosphodiesterase type 4 (PDE4) with a Ki value of 0.07 μM. This inhibition leads to the accumulation of cAMP, which activates protein kinase A (PKA</p>Formula:C10H11N5O5PS·NaPurity:Min. 95%Molecular weight:367.25 g/mol2',3'-Stannyluridine
<p>2',3'-Stannyluridine is a novel modified ribonucleoside. It is synthesized by the condensation of 2'-deoxyuridine and 3'-hydroxy-2-methylpropiophenone. This product has been shown to have anticancer and antiviral activities. 2',3'-Stannyluridine inhibits the synthesis of DNA, RNA, and protein in cells by binding to the ribonucleotide reductase enzyme. It also has an effect on phosphoramidite synthesis, which is an important step in DNA replication. The CAS number for this product is 57824-03-1.</p>Purity:Min. 95%5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite
CAS:<p>5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite is a high purity, novel, modified, antiviral and anticancer nucleotide. It is an analog of thymidine which has the methyl group at the 5' position replaced with a 5' amino group. This modification prevents conversion of the nucleoside to thymine and therefore inhibits DNA synthesis. The phosphoramidite is used as a building block for oligonucleotides in chemical synthesis. The phosphoramidite has shown antiviral activity against HIV by preventing reverse transcription of viral RNA into DNA. It also has been tested for its anticancer effects on human cells in vitro by inhibiting DNA synthesis and inducing apoptosis in cancer cells.</p>Formula:C39H48N5O6PPurity:Min. 95%Molecular weight:713.8 g/mol2',3'-Dideoxy-2',3'-didehydroinosine
CAS:<p>2',3'-Dideoxy-2',3'-didehydroinosine is a synthetic pyrimidine compound that has been shown to inhibit tumor growth in animal models. It is used to prepare 2',3'-dideoxy-2',3'-didehydroinosine-5'-triphosphate, which inhibits the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase. This inhibition leads to cell death by inducing crosslinkers and inhibiting polymerase chain reaction. 2',3'-Dideoxy-2',3'-didehydroinosine can be synthesized from hydrochloric acid and carbonyl compounds such as glyoxal, acetaldehyde, or benzaldehyde.<br>2',3'-Dideoxy-2',3'-didehydroinosine is an important part of phylogenetic tree analysis because it provides information about evolutionary relationships between bacteria.</p>Formula:C10H10N4O3Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:234.21 g/molCyclic diguanosine monophosphate
CAS:<p>Cyclic diguanosine monophosphate (c-di-GMP) is a nucleotide that is involved in bacterial cell signaling. It has been shown to be essential for the formation of bacterial biofilms and plays an important role in the development of infectious diseases. c-di-GMP is synthesized from guanosine triphosphate through a series of enzymatic reactions and then hydrolyzed by cyclic diguanosine monophosphatase, which leads to its termination as a second messenger. c-di-GMP interacts with proteins that regulate the expression of genes involved in biofilm formation, motility, and virulence. The synthesis and hydrolysis of c-di-GMP are regulated by multiple enzymes, including protein phosphatases, that control cellular physiology such as biofilm formation.</p>Formula:C20H24N10O14P2Purity:Min. 95%Molecular weight:690.41 g/mol3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine
CAS:<p>3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine is a novel nucleoside that is used for the synthesis of DNA and RNA. It is a modified nucleoside with antiviral and anticancer properties. 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine has been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in cultured cells. In addition to its antiviral activity against HIV type 1 (HIV-1), 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine also inhibits the growth of cancerous cells by acting as an inhibitor of DNA</p>Formula:C22H40N2O7Si2Purity:Min. 95%Molecular weight:500.73 g/mol3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine
<p>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is a novel nucleoside with antiviral and anticancer properties. It has been shown to inhibit the growth of human tumor cells in culture and induce apoptosis, as well as inhibit viral replication. 3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is an analogue of uridine, which can be used for the synthesis of DNA or RNA. The phosphate group is attached to the 3' carbon on the sugar moiety. This nucleoside has been modified from a natural ribonucleoside by substitution of a tertiary butylphenylsilyl group at the 2' position with an o-methyl group.<br>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is supplied as a white powder with purity greater than 99</p>Purity:Min. 95%6-Propylamino-7-deazapurine
CAS:<p>6-Propylamino-7-deazapurine is a synthetic nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and is modified to have a high quality. 6-Propylamino-7-deazapurine has been shown to be effective against HIV and other viruses in vitro, as well as in animal models, but it is not yet approved for use in humans.6-Propylamino-7-deazapurine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Formula:C9H12N4Purity:Min. 95%Molecular weight:176.22 g/mol2',3'-Di-O-methylguanosine
<p>2',3'-Di-O-methylguanosine is a nucleoside, which is a chemical compound composed of a nitrogenous base, a five-carbon sugar, and one phosphate group. It is an analog of guanosine that has been modified by replacing the 2' hydroxyl group with a methyl group. This modification prevents the phosphorylation of the monophosphate form to the diphosphate form. This modification also makes 2',3'-Di-O-methylguanosine an activator of DNA polymerase and RNA polymerase. The novel features of this compound make it an excellent candidate for anticancer and antiviral treatments.</p>Purity:Min. 95%2-[2-(2-Naphthalenyl)ethoxy]adenosine
CAS:<p>2-[2-(2-Naphthalenyl)ethoxy]adenosine is a structural determinant that belongs to the class of adenosine derivatives. It is an antagonist of adenosine receptors, binding to the A1 receptor with high affinity and blocking the effects of adenosine. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has been shown to have a high affinity for benzyl and thioether groups in its structure, which are important for binding to the A1 receptor. This compound has been used in assays to determine the binding of other compounds with adenosine receptors. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has also been shown as a radioligand for competitive binding studies with human brain membranes.</p>Formula:C22H23N5O5Purity:Min. 95%Molecular weight:437.45 g/mol3'-O-DMT-thymidine
CAS:<p>3'-O-DMT-thymidine is a nucleoside analogue that is synthesized from thymidine. It has been shown to bind to the proviral dna of HIV and inhibit viral replication when present in a complex with the other nucleosides. 3'-O-DMT-thymidine is also stable at high temperatures and binds to carboxamide groups on proteins. This compound has been shown to be effective as a binder for surfaces and membranes, which may be due to its ability to form stable complexes with terminal phosphates. The stability of these complexes can be influenced by the presence of denaturants such as temperature, pH, or ionic strength parameters. 3'-O-DMT-thymidine also forms stable complexes with linkers that are sensitive to thermal denaturation.</p>Formula:C31H32N2O7Purity:Min. 95%Molecular weight:544.6 g/mol2',3',5'-Tri-O-acetyl-N2-dimethylguanosine
CAS:<p>2',3',5'-Tri-O-acetyl-N2-dimethylguanosine is a novel modified nucleoside. It is a monophosphate that has been shown to be an activator of DNA and RNA synthesis, which can lead to the production of cancer cells. 2',3',5'-Tri-O-acetyl-N2-dimethylguanosine also has antiviral and antibacterial properties, as well as anticancer activity. This compound is used as a phosphoramidite in the synthesis of oligonucleotides for use in research and therapeutic applications.</p>Formula:C18H23N5O8Purity:Min. 95%Molecular weight:437.4 g/mol6-O-Benzyl-2'-deoxyguanosine
CAS:<p>6-O-Benzyl-2'-deoxyguanosine is a synthetic nucleoside analog that inhibits the synthesis of DNA. It is used in animal studies as a pancreatic carcinogen, and has been shown to inhibit tumor growth in mice. This drug specifically binds to DNA at the O6 position of guanine and methylates the adjacent cytosine residue, thereby preventing synthesis of DNA. 6-O-Benzyl-2'-deoxyguanosine also inhibits the activity of an enzyme called methyltransferase, which converts S-adenosylmethionine into S-adenosylhomocysteine, an intermediate in one of the pathways that produce methionine from homocysteine. This inhibition leads to an accumulation of methionine and its metabolites, including homocysteine and cystathione beta synthase, which can cause cell death.</p>Formula:C17H19N5O4Purity:Min. 95%Molecular weight:357.36 g/molN4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite
CAS:<p>N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite is a novel nucleoside. It is a monophosphate and cytidine analog that has been shown to be effective in the treatment of cancer. N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite also inhibits viral replication by preventing the synthesis of DNA and RNA. This drug can be used as an activator for synthesis of modified oligonucleotides.</p>Formula:C41H50N5O8PPurity:Min. 95%Molecular weight:771.84 g/molN3-Methyl-2'-O-methyluridine
CAS:<p>2'-O-methyluridine is an antiviral nucleoside that is used as a phosphoramidite in the synthesis of oligonucleotides. It has been shown to inhibit viral replication, and has been found to be effective in treating HIV-1 by inhibiting reverse transcriptase. N3-Methyl-2'-O-methyluridine also inhibits DNA synthesis and cell proliferation, and may be useful for the treatment of cancer. This modified nucleoside has been synthesized from uracil and contains a methyl group at the 3' position. The methyl group prevents 2'-O-methyluridine from being activated by cellular thymidylate synthase, which normally converts deoxyribonucleotides into ribonucleotides. This novel nucleotide has not yet been used in clinical trials but it may provide an alternative to other drugs used for cancer treatments.</p>Formula:C11H16N2O6Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:272.25 g/molN6,5'-O-Dibenzoyl-2'-deoxy-adenosine
<p>N6,5'-O-Dibenzoyl-2'-deoxy-adenosine is a monophosphate nucleoside that is used in the synthesis of DNA. It is synthesized from 2'-deoxyadenosine, which is an antiviral agent against influenza virus and anticancer agent. N6,5'-O-Dibenzoyl-2'-deoxy-adenosine has been shown to be a potent activator of the polymerase chain reaction with high purity and novel properties.</p>Formula:C24H21N5O5Purity:Min. 95%Molecular weight:475.45 g/molL-Ribose NAD
<p>L-Ribose NAD is a nucleoside that belongs to the group of ribonucleosides. It is a novel modified monophosphate and diphosphate nucleotide. L-Ribose NAD has antiviral, anticancer, and immunomodulatory activities. L-Ribose NAD can activate cells with DNA damage by inhibiting the synthesis of deoxyribonucleosides, which are needed for DNA repair. This product has a high purity level and high quality.</p>Purity:Min. 95%Molecular weight:663 g/molN2-DMF-2'-O-methylguanosine
CAS:<p>N2-DMF-2'-O-methylguanosine is a nucleoside that is used as an antiviral agent and anticancer drug. It has been shown to inhibit the growth of human cancer cells in vitro and in vivo. N2-DMF-2'-O-methylguanosine has also been shown to inhibit viral replication by inhibiting DNA synthesis. This nucleoside is a novel compound that can be synthesized using phosphoramidites, which are high quality and yield high purity products.</p>Formula:C14H20N6O5Purity:Min. 95%Molecular weight:352.35 g/mol4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranose
CAS:<p>4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.</p>Formula:C17H19N5O4Purity:Min. 95%Molecular weight:357.36 g/mol5'-O-DMT-2'-O-hexylaminoadenosine
<p>5'-O-DMT-2'-O-hexylaminoadenosine is a modified nucleoside that has antiviral activity. It is the monophosphate form of 5'-O-DMT-2'-O-hexylaminoadenosine, and it is used in the synthesis of phosphoramidites for DNA and RNA. This nucleoside is also an activator for novel antiviral drugs.</p>Formula:C37H44N6O6Purity:Min. 95%Molecular weight:668.8 g/mol5-[(Methylamino)methyl]uridine
CAS:<p>5-[(Methylamino)methyl]uridine is a proton-containing analog of uridine. It is an epigenetic modifier that has been shown to have conformational properties that are similar to those of uridine. 5-[(Methylamino)methyl]uridine has been shown to modify the glycosidic bond and ring structures, which are important for its function in protein synthesis. The compound can also be found as a chemical structure in the ribosomal subunit, where it is involved in protein synthesis and translation. 5-[(Methylamino)methyl]uridine has shown potential as a therapeutic agent for cancer treatment due to its ability to inhibit the expression of oncogenes in cells and induce programmed cell death (apoptosis).</p>Formula:C11H17N3O6Purity:Min. 95%Molecular weight:287.27 g/mol2-Amino-4-methoxypyrimidine
CAS:<p>2-Amino-4-methoxypyrimidine is an organic compound that can be synthesized from 2-amino-4-chloropyrimidine. It is a colorless, water soluble solid with a melting point of 166°C. The UV spectrum of 2-amino-4-methoxypyrimidine exhibits absorption maxima at 240 nm and 280 nm. When 2-amino-4-methoxypyrimidine is exposed to UV light, it emits fluorescent light at 360 nm. The IR spectrum exhibits absorption bands at 3200 cm−1, 1650 cm−1, and 1530 cm−1. Hydrogen bonding interactions occur between the methoxy group and the protonated amine group in the molecule's structure. The yield of this reaction was found to be 65% by GC analysis. This reaction occurs in two steps: first, the imino group reacts with n hexane to form an iminium ion</p>Purity:Min. 95%2'-Deoxy-5'-O-DMT-adenosine
CAS:<p>2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.</p>Formula:C31H31N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:553.61 g/mol[1',2',3',4',5'-13C5]-4-Thiothymidine
<p>[1',2',3',4',5'-13C5]-4-Thiothymidine is an antiviral, anticancer, and activator of DNA synthesis. It is a monophosphate analog of thymidine that has been modified to include a radioactive isotope. [1',2',3',4',5'-13C5]-4-Thiothymidine binds to the active site of the enzyme ribonucleotide reductase which is responsible for the production of DNA from RNA. The incorporation of this radioactively labeled analog into DNA prevents its degradation by nucleases and allows for the detection and quantification of DNA synthesis via autoradiography.</p>Purity:Min. 95%2'-Deoxy-1,N6-dimethyladenosine
<p>2'-Deoxy-1,N6-dimethyladenosine is a nucleoside that is used for the synthesis of DNA and RNA. It has antiviral activity against HIV and herpes simplex virus type 1 (HSV-1). 2'-Deoxy-1,N6-dimethyladenosine binds to viral DNA and inhibits viral replication by preventing the viral DNA from being replicated. It also inhibits the synthesis of viral proteins. This nucleoside is synthesized in a high purity and quality, which makes it an excellent starting material for use in the synthesis of other nucleosides or phosphoramidites.</p>Purity:Min. 95%(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-d
CAS:<p>(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-</p>Formula:C31H26FN3O7Purity:Min. 95%Molecular weight:571.55 g/molInosine-3',5'-cyclic-monophosphate free acid
CAS:<p>Inosine-3',5'-cyclic-monophosphate free acid is an ester of inosine 3',5'-cyclic-monophosphate that is structurally related to adenosine. It has been shown to have a physiological function as a cyclic nucleotide phosphodiesterase inhibitor, and also inhibits voltage-dependent calcium channels. Inosine-3',5'-cyclic-monophosphate free acid has been shown to be effective against infectious diseases, such as Mycobacterium tuberculosis and Galleria mellonella. It has also been shown to reduce the production of peptide hormones, nucleotides, and cyclic AMP (cAMP). Inosine-3',5'-cyclic-monophosphate free acid does not exhibit any pharmacological activity on its own but can modulate the activities of other pharmacological agents.</p>Formula:C10H11N4O7PPurity:Min. 95%Molecular weight:330.19 g/molAFB-guanine
CAS:<p>AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.</p>Formula:C22H17N5O8Purity:Min. 95%Molecular weight:479.4 g/mol5-Methylcytidine HCl
<p>5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.</p>Formula:C10H15N3O5·HClPurity:Min. 95%Molecular weight:293.7 g/mol2-[2-(4-Fluorophenyl)ethoxy]adenosine
CAS:<p>2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.</p>Formula:C18H20FN5O5Purity:Min. 95%Molecular weight:405.38 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a high purity, Ribonuclesides, Anticancer, High quality, Antiviral, Nucleosides, CAS No. 118380-84-0, Deoxyribonucleosides, Modified, monophosphate and Phosphoramidites. It is an important reagent for the synthesis of DNA and RNA oligonucleotides. This product has novel properties as an anticancer drug and antiviral agent.</p>Formula:C52H66N5O9PSiPurity:Min. 95%Color and Shape:PowderMolecular weight:964.19 g/mol2,5'-Anhydro-thymidine
CAS:<p>2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.</p>Formula:C10H12N2O4Purity:Min. 95%Molecular weight:224.21 g/mol2-Methylthio-N6-methyladenosine
CAS:<p>2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.</p>Formula:C12H17N5O4SPurity:Min. 95%Color and Shape:White PowderMolecular weight:327.36 g/mol2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite
<p>2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite is a modified nucleoside monophosphate with antiviral and anticancer activity. It is synthesized by the reaction of 2'-deoxyguanosine 5'-O-DMT (dG) with 4-isopropylphenoxyacetic acid in the presence of triethylamine and tetrazole. The product is purified by crystallization.<br>This compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in human lymphocytes, which may be due to its ability to inhibit the synthesis of DNA, RNA, or both.</p>Formula:C49H59N6O9PPurity:Min. 95%Molecular weight:907.03 g/mol2-Fluoroinosine
CAS:<p>2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis.<br>2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug has</p>Formula:C10H11FN4O5Purity:Min. 95%Molecular weight:286.22 g/mol5'-Amino-2',5'-dideoxyuridine
CAS:<p>5'-Amino-2',5'-dideoxyuridine (5-ADU) is a pyrimidine nucleoside that is structurally similar to thymidylate, which it inhibits. 5-ADU is used in the treatment of viral infections and cancers, as well as in the prevention of radiation injury. It has been shown to be an effective antiviral agent against herpes virus and some DNA viruses, such as adenovirus, vaccinia virus, and poliovirus. 5-ADU also enhances the effects of azauridine and other pyrimidine nucleosides in bacterial enzymes such as E. coli. 5-ADU has not been shown to be active against uninfected cells or tissues.</p>Formula:C9H13N3O4Purity:Min. 95%Molecular weight:227.22 g/mol2-Methanesulfonyl-pyrimidine
CAS:<p>2-Methanesulfonyl-pyrimidine is a thiourea that is used as a catalyst in organic synthesis. It can be prepared by reacting phosphorus oxychloride with malonate and hydrochloric acid at temperatures of about 0°C to 150°C. The chloride anion is replaced by the sulfonyl chloride, which has high affinity for the 2-position of thiourea. This reaction leads to an intermediate that can be hydrolyzed with hydrochloric acid to produce 2-methanesulfonyl-pyrimidine. 2-Methanesulfonyl-pyrimidine is soluble in water and can be used as a catalyst in wastewater treatment processes, such as cyclic oxidation or oxychlorination reactions.</p>Purity:Min. 95%8-Bromo-5'-o-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine
CAS:<p>8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.</p>Formula:C34H35BrN6O6Purity:Min. 95%Molecular weight:703.6 g/mol2'-Deoxy-N6,N6-dimethyladenosine
<p>2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.</p>Purity:Min. 95%2,6-Diamino-9-(3'-amino-2',3'-dideoxy-β-D-ribofuranosyl)purine
CAS:<p>2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is an antiviral agent that inhibits the replication of the viral DNA by binding to the viral DNA and preventing its transcription into RNA. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). 2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is a modified nucleoside that can be used in various areas of research, including antiviral and anticancer activities.</p>Formula:C10H15N7O2Purity:Min. 95%Molecular weight:265.28 g/mol2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
<p>2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0</p>Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.</p>Purity:Min. 95%2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine
CAS:<p>2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.</p>Formula:C19H20N2O7Purity:Min. 95%Molecular weight:388.37 g/mol5'-O-DMT-N2-phenylacetylguanosine
CAS:<p>5'-O-DMT-N2-phenylacetylguanosine is a novel synthetic nucleoside phosphoramidite which can be used for the synthesis of modified oligonucleotides. It has been shown to be an activator, anticancer, and antiviral agent in vitro. 5'-O-DMT-N2-phenylacetylguanosine is also a monophosphate, which can inhibit viral replication by interacting with the ribose sugar moiety of the nucleic acid strand. The antiviral activity has been demonstrated on human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus.</p>Formula:C39H37N5O8Purity:Min. 95%Molecular weight:703.76 g/molAdenosine-5'-carboxylic acid
CAS:<p>Adenosine-5'-carboxylic acid is a pharmaceutical compound that is used as an anti-inflammatory agent. It is a synthetic, non-nucleoside adenine nucleotide analog that has been shown to have potent anti-inflammatory activity in vitro. Adenosine-5'-carboxylic acid inhibits the synthesis of prostaglandins and leukotrienes which are mediators of inflammation. It also inhibits the synthesis of protein kinase C, which plays a role in cell proliferation, differentiation and apoptosis. Adenosine-5'-carboxylic acid has also been found to inhibit the growth of glioma cells in tissue culture and human muscle cells in vivo. The mechanism for this effect may be due to its ability to inhibit DNA synthesis and induce apoptosis.</p>Formula:C10H11N5O5Purity:Min. 95%Molecular weight:281.23 g/mol2-Methylthio-6-chloropurine
CAS:<p>2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.</p>Formula:C6H5CIN4SPurity:Min. 95%Molecular weight:304.11 g/mol5'-O-DMT-2'-fluoro-2'-deoxyinosine
CAS:<p>5'-O-DMT-2'-fluoro-2'-deoxyinosine is a novel nucleoside that has been modified with 2'-fluoro and 2'-deoxy substitutions. It is phosphoramidite, which can be activated by any of the standard methods to make DNA or RNA. 5'-O-DMT-2'-fluoro-2'-deoxyinosine is synthesized from DMT and fluoroacetyl chloride in the presence of triethylamine. This nucleoside has antiviral activity against HIV and influenza A virus, as well as anticancer effects.</p>Formula:C31H29FN4O6Purity:Min. 95%Molecular weight:572.58 g/mol2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine
<p>2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine is a novel ribonucleoside that has been synthesized as a phosphoramidite. It is an anticancer agent with antiviral and antiretroviral properties. The 2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine is a modified nucleoside that has the potential to be used in the treatment of certain cancers. It can also be used to inhibit viral replication by inhibiting RNA synthesis. This compound inhibits the enzyme diphosphate kinase, which converts ATP into ADP and phosphate. This leads to an accumulation of ADP in cells and inhibition of DNA synthesis.</p>Formula:C9H10F2N2O5Purity:Min. 95%Molecular weight:264.18 g/molAdenosine 5'-monophosphate [U-13C10,U-15N5]
CAS:<p>Adenosine 5'-monophosphate (AMP) is a nucleoside that is used in the synthesis of DNA, RNA and other nucleic acids. AMP is also an antiviral and anticancer agent that can be used to activate other drugs. AMP is synthesized from adenosine triphosphate (ATP) by removing one phosphate group, resulting in the formation of adenosine diphosphate (ADP). ADP can then be converted to AMP by adding a phosphate group back on. This synthetic process can be modified to produce novel derivatives of AMP with enhanced properties.</p>Formula:C10H14N5O7PPurity:Min. 95%Molecular weight:362.11 g/mol2',3'-O-Isopropylidene-6-thioinosine
CAS:<p>2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.<br>2',3'-O-Isopropylidene-6-thioinos</p>Formula:C13H16N4O4SPurity:Min. 95%Molecular weight:324.36 g/molDiethyl N-(tert-Butoxycarbonyl)phosphoramidate
CAS:<p>Diethyl N-(tert-Butoxycarbonyl)phosphoramidate is a chemical compound that is used in coupling reactions. It has a magnetic resonance and can be used to detect the presence of certain elements. Diethyl N-(tert-Butoxycarbonyl)phosphoramidate shifts at 12.2 ppm, which is higher than the normal chemical shift for an ester of this type. The magnetic resonance data for Covid-19 pandemic, Covid-19, and 3D-19 are all constant with Covid-19 pandemic being the most intense. Covid-19 pandemic has a structural formula of C8H16O4N2S, which is different from Covid-19 and 3D-19, which have structural formulas of C8H14O4N2S. The three compounds have similar chemical shifts with covid-19 having a slightly higher frequency than covid-19 pandemic</p>Formula:C9H20NO5PPurity:Min. 95%Molecular weight:253.23 g/mol2'-Deoxy-2',2'-difluoroguanosine
CAS:<p>2'-Deoxy-2',2'-difluoroguanosine (DFG) is an analog of guanosine that has been used to study the effect of guanylate kinase on cellular proliferation. This compound has also been shown to have a cytotoxic effect on leukemia cells. DFG has been shown to inhibit the growth of cancer cells and induce apoptosis in HL-60 leukemia cells. It has also been shown to inhibit the synthesis of DNA, RNA, and proteins. These effects are due to inhibition of guanylate kinase activity and may be related to its ability to cause the release of intracellular calcium ions.</p>Formula:C10H11F2N5O4Purity:Min. 95%Molecular weight:303.22 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is a monophosphate nucleoside that is synthetically modified. It has anticancer activity and can be used to treat viral infections. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is also a novel nucleoside that exhibits antiviral and antitumor properties. This compound can be used as an intermediate in the synthesis of DNA, ribonucleosides, and deoxyribonucleosides.</p>Formula:C39H49N4O7PPurity:Min. 95%Molecular weight:716.8 g/mol3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt
<p>3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.</p>Purity:Min. 95%Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt
CAS:<p>Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.</p>Formula:C20H26N7O10P·NH3Purity:Min. 95%Molecular weight:572.47 g/mol3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester
Controlled Product<p>3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester (AZT) is a novel nucleoside compound that is a phosphoramidite. AZT has antiviral activity against various DNA and RNA viruses, including HIV. It is also effective in the treatment of cancer. AZT inhibits viral replication by competitively inhibiting the incorporation of diphosphate into viral DNA or RNA. This process prevents the synthesis of new virus particles and the spread of infection to healthy cells. In addition, AZT may inhibit tumor growth by interfering with cell division and DNA synthesis.</p>Formula:C23H26D3N5O13Purity:Min. 95%Molecular weight:586.52 g/mol5-Bromo-2-(2-methoxyethylamino)pyrimidine
CAS:<p>5-Bromo-2-(2-methoxyethylamino)pyrimidine is a novel, ribonucleoside that exhibits anticancer activity. It inhibits DNA synthesis and viral replication by binding to the ribonucleotide reductase enzyme. 5-Bromo-2-(2-methoxyethylamino)pyrimidine is synthesized from phosphoramidites and has been shown to have antiviral and antifungal activities. The drug inhibits the enzyme's activity by mimicking natural nucleosides and monophosphates. It is also modified with an amino group to increase its stability against chemical degradation.</p>Purity:Min. 95%dATP - 100 mmol solution
CAS:<p>aATP is useful in molecular biology applications including PCR/qPCR, reverse transcription, DNA labelling and DNA sequencing.</p>Formula:C10H16N5O12P3Purity:Min. 95%Molecular weight:491.18 g/mol2',3'-Dideoxyuridine-5'-O-monothiophosphate
CAS:<p>2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.</p>Formula:C9H13N2O6PSPurity:Min. 95%Molecular weight:308.25 g/mol1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one
CAS:<p>1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one is a nucleoside that has been modified to have anticancer properties. The drug is an activator of the enzyme ribonucleotide reductase, which is responsible for making deoxyribonucleotides from ribonuclesides. 1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one inhibits viral replication by inhibiting the activity of DNA polymerase and preventing RNA synthesis. This drug also inhibits human immunodeficiency virus type 1 (HIV) reverse transcriptase and is used as an antiviral agent.</p>Formula:C10H12N2O7Purity:Min. 95%Molecular weight:272.21 g/mol3-Deazaguanosine
CAS:<p>3-Deazaguanosine is a nucleotide that is found in uridine, which is present in the nucleic acids of all cells. It has been shown to be cytotoxic to colorectal adenocarcinoma and carcinoma cell lines, and this cytotoxicity may be due to its ability to inhibit energy metabolism. 3-Deazaguanosine has also been shown to significantly inhibit viral replication, including HIV and herpes simplex virus type 1. It binds with high affinity to monoclonal antibodies that are specific for nucleotide levels. 3-Deazaguanosine inhibits tissue culture enzyme activity and can cause significant changes in adenine nucleotide levels in cell culture.</p>Formula:C11H14N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:282.25 g/molBiotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
<p>Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a monoclonal antibody. It is used in the diagnosis of lung cancer. The antibody binds to markers present on the tumor cells and can be detected by immunohistochemistry (IHC) or immunofluorescence (IF). The antibody may also be used to identify submucosal tumors that are not palpable.</p>Formula:C22H34N5O17P3S·xLiPurity:Min. 95%Molecular weight:765.52 g/mol5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1)
CAS:<p>5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1) is a novel monophosphate nucleoside that has been synthesized and evaluated in vitro as an anticancer agent. It inhibits the proliferation of various human tumor cell lines, including breast cancer cells. This compound is also active against HIV-1 virus but not against other viruses tested. 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1), like other nucleosides, can be modified to suit particular needs and then used for therapeutic purposes.</p>Formula:C31H33N2O9PPurity:Min. 95%Molecular weight:608.58 g/mol3'-Epi gemcitabine
CAS:<p>3'-Epi-GEMCITABINE is a nucleoside phosphoramidite that is used in the synthesis of DNA and RNA. It is an antiviral agent and also has anticancer activity. 3'-Epi-GEMCITABINE inhibits the growth of cells by inhibiting DNA synthesis, which leads to cell death. The chemical name for 3'-epigemcitabine is 2',3'-dideoxyinosine monophosphate. 3'-Epi-GEMCITABINE can be synthesized from 2',3'-dideoxyinosine monophosphate and 5-bromo-2'-deoxyuridine diphosphate.</p>Formula:C9H11F2N3O4Purity:Min. 95%Molecular weight:263.2 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)uridine
CAS:<p>5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.</p>Formula:C33H36N2O9Purity:Min. 95%Molecular weight:604.65 g/mol5-Azauridine
CAS:<p>5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.</p>Formula:C8H11N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:245.19 g/molN4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
<p>N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have anticancer effects in vitro and in vivo by inducing apoptosis and cell cycle arrest. This compound has also been shown to be more potent than other nucleosides, such as cytidine 5'-diphosphate (CDP) or cytidine 5'-monophosphate (CMP). This chemical is not yet commercially available but can be custom synthesized for research purposes.</p>Formula:C52H64N5O10PPurity:Min. 95%Molecular weight:950.07 g/molN4-Acetyl-3'-O-acetyl-2'-deoxycytidine
CAS:<p>N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is a novel, modified nucleoside that contains a phosphoramidate linkage. It has been shown to have anticancer and antiviral properties. N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is also an activator of the immune system and has been shown to be effective against HIV.</p>Purity:Min. 95%2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite
CAS:Controlled Product<p>2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite is a modified nucleoside that is used as an antiviral agent. It is synthesized by modifying the 2'-deoxyribose sugar with a 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyrylguanosine 3' phosphate. This compound has shown anticancer activity in vitro and has been studied in animal models. The synthesis of this compound can be accomplished through the use of diphosphate, which gives it an advantage over natural nucleosides because it does not require ribonucleotides.</p>Formula:C54H57F17N7O8PPurity:Min. 95%Molecular weight:1,286.02 g/molO6-Benzyl-N2,3-etheno guanosine
CAS:<p>O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.</p>Formula:C19H19N5O5Purity:Min. 95%Molecular weight:397.38 g/mol4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid
CAS:<p>4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid is a novel monophosphate and nucleotide analogue, which can activate the HIV reverse transcriptase. It has been shown to be cytotoxic to cancer cells in vitro. 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid has been used for the synthesis of phosphoramidites and DNA and RNA analogues.</p>Formula:C6H4F2N2O3Purity:Min. 95%Molecular weight:190.1 g/molThymidine-3',5'-tetrabenzyldiphosphate
<p>Thymidine-3',5'-tetrabenzyldiphosphate is a monophosphate analog of thymidine. It has been used as a building block for the synthesis of DNA, RNA, and phosphoramidites. Thymidine-3',5'-tetrabenzyldiphosphate is a novel nucleoside compound that has been shown to have anticancer and antiviral activities. This product is intended for research purposes only.</p>Formula:C38H40N2O11P2Purity:Min. 95%Molecular weight:762.68 g/mol2-Chloropyrimidine-4-carboxamide
CAS:<p>2-Chloropyrimidine-4-carboxamide is an activator that is a novel chemical entity of deoxyribonucleosides, phosphoramidites, ribonuclesides, and antiviral nucleosides. It has been shown to have high purity and quality. 2-Chloropyrimidine-4-carboxamide has been used in the synthesis of oligodeoxynucleotides for antiviral activity.</p>Formula:C5H4ClN3OPurity:Min. 95%Molecular weight:157.56 g/mol5-Isopropyl-2'-deoxyuridine
CAS:<p>5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.</p>Formula:C12H18N2O5Purity:Min. 95%Molecular weight:270.28 g/molGuanosine 5'-[β,γ-imido]triphosphate tetralithium hydrate
CAS:<p>Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.</p>Formula:C10H13Li4N6O13P3Purity:Min. 95%Molecular weight:546 g/mol7-Deaza-2-mercaptohypoxanthine
CAS:<p>7-Deaza-2-mercaptohypoxanthine is a nucleoside that has been found to have anticancer activity in vivo. It has also been shown to inhibit the replication of HIV and herpes simplex virus. 7-Deaza-2-mercaptohypoxanthine is an analog of hypoxanthine, which is a nucleoside that can be found in DNA and RNA. In addition, this compound can be used as a phosphoramidite or nucleotide analogue for the synthesis of DNA and RNA. This compound can also be used as an antiviral agent against herpes simplex virus type 1 (HSV1).</p>Formula:C6H5N3OSPurity:Min. 95%Molecular weight:167.19 g/mol5'-O-DMT-inosine
CAS:<p>5'-O-DMT-inosine is a novel monophosphate nucleotide analogue. It is modified by the attachment of an aminooxy group to the 5' position of the pentose. This modification prevents ribonucleotide reductase from converting it into deoxyribonucleotides, which are then incorporated into DNA. 5'-O-DMT-inosine has been shown to be cytotoxic in human leukemia cells due to its ability to inhibit the synthesis of DNA and RNA.</p>Formula:C31H30N4O7Purity:Min. 95%Molecular weight:570.59 g/mol7-Methylinosine
CAS:<p>7-Methylinosine is a versatile compound that has various applications in different fields. It is used as an intermediate in the synthesis of drugs such as azasetron, eletriptan, and fructan. Additionally, it has been shown to have detergent properties that make it useful in cleaning products. 7-Methylinosine also plays a role in cholesterol metabolism and has been implicated in the development of fibrosis. Studies have found that this compound can inhibit the activity of enzymes involved in glucosinolate biosynthesis and may play a role in plant defense against pathogens. Furthermore, 7-Methylinosine has been isolated from Nocardia sp., which suggests its potential use as a source of novel bioactive compounds.</p>Formula:C11H16N4O5Purity:Min. 95%Molecular weight:284.27 g/mol2'-Deoxy-N3-methylcytidine hydroiodide salt
CAS:<p>2'-Deoxy-N3-methylcytidine hydroiodide salt is a nucleoside and phosphoramidite. It is used as an anticancer agent that inhibits DNA synthesis. It also has antiviral and antitumor effects. The chemical name for 2'-deoxy-N3-methylcytidine hydroiodide salt is 2'-deoxy-N3-methylcytidine, monophosphate salt with hydroiodic acid. This drug does not have a CAS number because it's not commercially available.</p>Formula:C10H17N3O4·HIPurity:Min. 95%Color and Shape:PowderMolecular weight:371.17 g/mol2-(2-Cyclohexylethoxy)adenosine
CAS:<p>2-(2-Cyclohexylethoxy)adenosine (CX-5461) is a new chemical entity that has been shown to have an incremental effect on muscle contraction. The mechanism of action of CX-5461 is not fully understood, but it has been shown to be nonselective and to bind to adenosine receptors. This binding produces a response in the cell similar to that of adenosine, which is a small molecule involved in the regulation of blood pressure and heart rate. CX-5461 also binds with platelet membranes at the site of inflammation and causes vasodilation. It has been shown to be effective in animal models of pertussis, where it reduces the severity of muscle spasms and increases the duration before death. These effects are due to CX-5461's ability to lower intracellular calcium concentrations by preventing calcium release from internal stores or from outside sources such as muscle cells or platelets.</p>Formula:C18H27N5O5Purity:Min. 95%Molecular weight:393.44 g/mol7-Deaza-2'-deoxy-O6-methylguanosine
<p>7-Deaza-2'-deoxy-O6-methylguanosine is a novel nucleoside phosphoramidite that is the first of its kind to have been shown to be an antiviral agent. It is also anticancerous and stimulates diphosphate synthesis. 7-Deaza-2'-deoxy-O6-methylguanosine is a highly reactive nucleoside phosphoramidite that reacts with DNA in the same manner as deoxyribonucleotides. The monophosphate form of this compound has been shown to be anticancerous and stimulate diphosphate synthesis. This novel compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in vitro.</p>Formula:C12H16N4O4Purity:Min. 95%Molecular weight:280.28 g/mol7-Deaza-7-iodoguanosine
CAS:<p>7-Deaza-7-iodoguanosine is a novel, synthetic nucleoside analog that has antiviral and anticancer activity. It is modified by the addition of a 7-deaza substituent at the 2′ position of the ribose ring. The phosphoramidite form of this compound can be used to synthesize DNA and RNA for use in research and gene therapy. 7-Deaza-7-iodoguanosine may have anticancer activity due to its ability to inhibit protein synthesis by binding to diphosphate kinase, which prevents ATP production and inhibits protein synthesis.</p>Purity:Min. 95%Uridylyl-2'-5'-uridine ammonium salt
CAS:<p>Uridylyl-2'-5'-uridine ammonium salt is a monophosphate nucleoside that is a synthetic compound of uridine. It is an antiviral agent and has been shown to be effective against DNA viruses such as herpes simplex virus and Epstein-Barr virus. Uridylyl-2'-5'-uridine ammonium salt binds to the viral DNA, preventing the replication process from occurring. This drug also has anticancer properties, which are attributed to its ability to inhibit DNA synthesis in cells.</p>Formula:C18H23N4O14P·NH3Purity:Min. 95%Molecular weight:567.41 g/mol5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine
<p>5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine is a nucleoside analog that is used in the treatment of HIV. It inhibits viral replication by interfering with the viral reverse transcriptase enzyme and preventing it from transcribing the virus's genetic material. 5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine has also been shown to have anticancer properties. This drug has shown activity against cancer cells in vitro, although clinical trials are still needed to determine its effectiveness as a cancer therapy.</p>Formula:C12H16N4O6Purity:Min. 95%Molecular weight:312.28 g/molL-Cystine dihydrochloride
CAS:<p>L-Cystine dihydrochloride is a white crystalline powder that is used to treat acute radiation syndrome. It is an amino acid that contains two cysteine residues linked by a disulfide bond. Cysteine is necessary for the formation of proteins and peptides, which are important in antibody production. L-Cystine dihydrochloride has been shown to increase the uptake of radioactive substances in cells. This drug also increases the amount of bioactive molecules such as glutathione, which protects cells from oxidative damage caused by radiation. The effects of L-cystine dihydrochloride are dose dependent, with higher doses leading to greater cellular death.<br>The unpaired cysteines in L-cystine dihydrochloride can react with each other, forming a new molecule called S-thiolactone. This reaction is catalyzed by porcine pancreatic lipase (PPLL), a membrane protein found in pancreat</p>Formula:C6H14Cl2N2O4S2Purity:Min. 95%Molecular weight:313.2 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine
CAS:<p>3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine is a modified nucleoside that is used as an anticancer agent. This active form has been shown to have antiviral and antitumor activities. The drug is synthesized by reacting 2,4,6-trihydroxybenzoic acid with 2'-deoxyribose and then 2'-fluoroarabinonucleotidase. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine has high purity and high quality, which makes it suitable for use in the synthesis of phosphoramidites.</p>Purity:Min. 95%7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine
CAS:<p>7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.</p>Formula:C16H16F3N5O3Molecular weight:383.33 g/molRef: 3D-J-700297
1gTo inquire50mgTo inquire100mgTo inquire250mgTo inquire500mgTo inquire-Unit-ggTo inquireAdenosine 2',3'-O-phenylboronate
CAS:<p>Adenosine 2',3'-O-phenylboronate is a nucleoside that is used as an antiviral and anticancer drug. It is used in the treatment of AIDS, leukemia, and lymphoma. Adenosine 2',3'-O-phenylboronate inhibits viral replication by preventing the formation of viral DNA. This nucleoside has also been shown to have antitumor properties and can be used to inhibit cancer cell growth.<br>br>br><br>Adenosine 2',3'-O-phenylboronate can be modified with phosphoramidites, which allow for the synthesis of modified adenosine 2',3'-O-phenylboronates. These modifications include substituting one or more hydrogen atoms with a variety of substituents, including fluorines, chlorine, bromines, nitro groups, alkyl groups, alkoxy groups and others. This modification provides for a novel type of anti</p>Formula:C16H16BN5O4Purity:Min. 95%Molecular weight:353.14 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt
<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt is a novel, modified nucleoside analogue that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by competing with natural nucleosides during the process of nucleic acid synthesis. The drug binds to the enzyme ribonucleotide reductase, which is essential for DNA synthesis. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt has been shown to be effective in treating patients with cancer.</p>Purity:Min. 95%4-(Dimethoxymethyl)pyrimidine
CAS:<p>4-(Dimethoxymethyl)pyrimidine is a nitrogen heterocycle that is prepared by the reaction of formamide and nitrate. This compound has been shown to inhibit the replication of viruses such as HIV, herpes simplex virus type 2 (HSV-2), or vesicular stomatitis virus (VSV). 4-(Dimethoxymethyl)pyrimidine also binds to uracil in RNA, inhibiting RNA synthesis and leading to cell death. This compound can also be used as a precursor for the preparation of 2-aminopyrimidine, which is used in the synthesis of other compounds. 4-(Dimethoxymethyl)pyrimidine is used in organic synthesis for the preparation of benzene derivatives, such as nitrobenzene. This compound can also be synthesized by reacting formamide with toluene in an ultrasonic bath.</p>Formula:C7H10N2O2Purity:Min. 95%Molecular weight:154.17 g/molGuanosine hydrate
CAS:<p>Please enquire for more information about Guanosine hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C10H13N5O5·xH2OPurity:Min. 98 Area-%Molecular weight:283.24 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å is a novel and modified nucleoside with anticancer and antiviral properties. Activator is a high purity and quality monophosphate that can be used in the synthesis of ribonucleosides and deoxyribonucleosides. It can also be used as a building block for the synthesis of phosphoramidites, which are important reagents for DNA sequencing, gene therapy, and other applications.</p>Purity:Min. 95%2'-Deoxyxanthosine 5'-monophosphate
CAS:<p>2'-Deoxyxanthosine 5'-monophosphate is a nucleoside which is an activator of the DNA polymerase. It has antiviral activity and is used in the synthesis of oligonucleotides. 2'-Deoxyxanthosine 5'-monophosphate is also used as a phosphoramidite in the chemical synthesis of DNA, and can be modified with fluorine or other atoms to form synthetic analogues.</p>Purity:Min. 95%5'-Ethylcarboxamido-2-iodoadenosine
CAS:<p>5'-Ethylcarboxamido-2-iodoadenosine is a novel antiviral drug that belongs to the class of deoxyribonucleosides. It has been shown to inhibit viral replication at the level of DNA synthesis and RNA transcription. 5'-Ethylcarboxamido-2-iodoadenosine has shown activity against cancer cells as well as antiviral activity against HIV and influenza virus. This compound has also been shown to be an activator of phosphoramidites, which are used in many industrial chemical reactions. 5'-Ethylcarboxamido-2-iodoadenosine is synthesized from 2',3'-dideoxyadenosine by replacing the 3' hydroxyl group with ethyl carboxamide group. It is then reacted with iodine to give the final product, 5'-ethylcarboxamido-2-iodoadenosine.</p>Formula:C12H15IN6O4Purity:Min. 95%Molecular weight:434.19 g/mol2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine
CAS:<p>2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.</p>Formula:C11H8F3N3Purity:Min. 95%Molecular weight:239.2 g/mol2'-Ethylfluoro-5'-O-DMT-5-methylcytidine
<p>2'-Ethylfluoro-5'-O-DMT-5-methylcytidine is a novel antiviral agent that is synthesized from 2'-deoxyribonucleosides. This product has been shown to be an effective activator of the human immune system and has potent anticancer activity. It inhibits DNA synthesis and protein synthesis, which leads to the death of cancer cells. In addition, this product has a high purity and high quality.</p>Purity:Min. 95%N6-2-(4-Aminophenyl)ethyladenosine
CAS:<p>N6-2-(4-Aminophenyl)ethyladenosine is a carbamazepine prodrug that is converted to the active form, carbamazepine, by esterases. It has been shown to inhibit the binding of adenosine to adenosine receptor subtypes and to have an antagonistic effect on the activity of endogenous adenosine at these receptors. N6-2-(4-Aminophenyl)ethyladenosine has also been shown to act as an antagonist at the A3 adenosine receptor. This drug has been shown to reduce bronchoconstrictor responses in animal models and may be used for treating asthma.<br>N6-2-(4-Aminophenyl)ethyladenosine has also been shown in vitro studies using human papillary muscle cells to enhance polymerase chain reactions (PCR).</p>Purity:Min. 95%N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine
<p>N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine is a modified nucleoside with antiviral, anticancer and antiretroviral activity. It is a novel monophosphate that has been shown to be effective against hepatitis B and HIV. N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine inhibits the synthesis of viral DNA by acting as an activator of DNA polymerases.</p>Purity:Min. 95%N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:<p>N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.</p>Formula:C17H22N5O13P3·xNaPurity:Min. 95%Color and Shape:Colorless PowderMolecular weight:597.3 g/molMorpholino A monomer
CAS:<p>Morpholino A is a modified nucleoside amidite used to prepare morpholino oligomers</p>Formula:C38H37ClN7O4PPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:722.17 g/mol2',3',5'-Tri-O-acetyl-8-bromoguanosine
CAS:<p>2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.</p>Formula:C16H18BrN5O8Purity:Min. 95%Color and Shape:Off-White To Light (Or Pale) Yellow SolidMolecular weight:488.25 g/molm-Topolin riboside
CAS:<p>Functionalised adenosine riboside</p>Formula:C17H19N5O5Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:373.36 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt
<p>2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt is a synthetic nucleoside with antiviral and anticancer properties. It is an analog of adenosine 5'-triphosphate (ATP) in which the ribose sugar has been replaced by a 2'-O-(methoxyethyl) moiety. It has shown to be cytotoxic against cancer cells, and it is a potent activator of human telomerase, the enzyme that synthesizes telomeres at the end of chromosomes. This compound has been shown to have high purity and quality and does not have any CAS numbers assigned to it.</p>Formula:C13H18N5O13P3S·4NaPurity:Min. 95%Molecular weight:669.25 g/mol2'-Deoxy-a-adenosine
CAS:<p>2'-Deoxy-a-adenosine is a nucleoside that contains an adenine base. It has been studied for its biological properties, including its reaction with solution and its use as an antimicrobial agent. 2'-Deoxy-a-adenosine has been shown to inhibit the growth of bowel disease in mice by binding to the adenosine A3 receptor on the surface of cells. This nucleoside also binds to nuclear DNA and may be used as a pharmacological agent, but more research is needed to determine whether it would be effective against cancer cells. 2'-Deoxy-a-adenosine may also be useful as a potential drug target for the treatment of cancer due to its ability to bind with dna duplexes, which are found in all cancer cells.</p>Formula:C10H13N5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:251.25 g/molRibavirin 5'-triphosphate triethylammonium salt - 10 mM aqueous solution
CAS:<p>Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.</p>Formula:C8H15N4O14P3•(C6H15N)xPurity:Min. 95 Area-%Color and Shape:Clear LiquidMolecular weight:789.735'-O-Tosylthymidine
CAS:<p>5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.</p>Formula:C17H20N2O7SPurity:Min. 95%Molecular weight:396.42 g/mol2-Amino-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:<p>2-Amino-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analog that has been found to be effective in the treatment of leukemia.</p>Formula:C10H13N5O3Purity:(Hplc) Min. 98.00%Color and Shape:PowderMolecular weight:251.24 g/mol(-)-Emtricitabine triphosphate sodium salt
CAS:<p>Emtricitabine is a nucleoside reverse transcriptase inhibitor with activity against human immunodeficiency virus and hepatitis B virus</p>Formula:C8H9FN3Na4O12P3SPurity:Min. 95%Molecular weight:575.11 g/mol2-Fluoroadenosine
CAS:<p>2-Fluoroadenosine is a nucleoside that has shown high resistance to the enzyme cyclase. This property may be due to its structural and conformational properties, which are different from those of adenosine. 2-Fluoroadenosine has been shown to inhibit the synthesis of ATP in ventricular myocardium and fat cells, as well as increase levels of adenylate kinase in blood. It has also been shown to have potential as a drug target for autoimmune diseases, such as multiple sclerosis. 2-Fluoroadenosine can be used for biochemical and pharmacokinetic studies because it is rapidly metabolized by the liver and excreted in urine.<br>2-Fluoroadenosine can also be used to measure changes in the ratio of adenylate kinase:adenylate kinase reductase (AKAR) in blood plasma.</p>Formula:C10H12FN5O4Purity:Min. 95%Color and Shape:White Slightly Yellow PowderMolecular weight:285.23 g/mol[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:<p>[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate (TMP) is a Ribonucleoside and Deoxyribonucleoside Activator that is synthesized from Thymine (T), Thymidine (Td), and Phosphoramidites. TMP is a novel synthetic derivative of thymine with the ability to activate DNA synthesis reactions. TMP has been shown to provide high quality nucleotides with high purity in a single step reaction.</p>Formula:C31H34ClN4O5PPurity:Min. 95%Color and Shape:White To Light (Or Pale) Red SolidMolecular weight:609.05 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:<p>Inhibitor of adenylyl and guanylyl cyclase</p>Formula:C10H15N4O15P3·xC6H15NPurity:Min. 95%Color and Shape:Colorless PowderMolecular weight:524.17 g/molUridine diphosphate choline (UDPC) sodium
CAS:<p>Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.</p>Formula:C14H25N3O12P2•NaPurity:Min. 95%Color and Shape:PowderMolecular weight:512.3 g/molDMTr-TNA-C(Bz)-amidite
CAS:<p>Please enquire for more information about DMTr-TNA-C(Bz)-amidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C45H50N5O8PMolecular weight:819.9 g/mol2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine
CAS:<p>2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.</p>Formula:C9H10FN3O3Purity:Min. 95%Molecular weight:227.19 g/molGuanosine 5'-diphosphate sodium
CAS:<p>Pyruvate kinase substrate</p>Formula:C10H15N5O11P2•Na2Purity:Min. 95%Color and Shape:PowderMolecular weight:466.19 g/molCaffeoyl-coenzym A
CAS:<p>Please enquire for more information about Caffeoyl-coenzym A including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C30H42N7O19P3SPurity:Min. 95%Molecular weight:929.68 g/molN4-Acetyl-2'-O-tert-butyldimethylsilylcytidine
CAS:<p>N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine is a novel nucleoside that has been extensively studied for its anticancer and antiviral properties. It is a modified nucleoside that inhibits the production of DNA, RNA, and protein. This product is also used as an activator in the synthesis of oligonucleotides. N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine can be used in vitro to study the effects of different cancer cells on DNA replication. It has been shown to inhibit the growth of human leukemia cells in culture.</p>Formula:C17H29N3O6SiPurity:Min. 95%Color and Shape:PowderMolecular weight:399.51 g/molGuanosine5'-diphosphate
CAS:<p>Pyruvate kinase substrate</p>Formula:C10H15N5O11P2Purity:Min. 95%Color and Shape:PowderMolecular weight:443.2 g/mol2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite
<p>2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite is a 5'-3’ “reverse” (or “inverse”) amidite.</p>Formula:C44H54N7O8PPurity:Min. 95%Molecular weight:839.94 g/mol4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester
CAS:<p>Focuses is a chemical compound that does not have any known commercial or industrial uses.</p>Purity:Min. 95%Kinetin riboside-5'-monophosphate sodium salt
CAS:<p>Kinetin riboside-5'-monophosphate sodium salt is a synthetic nucleotide that has been modified to include a phosphate group at the 5' position. Kinetin riboside-5'-monophosphate sodium salt is an activator of DNA synthesis and can be used for the treatment of viral infections. It also shows anticancer activity and is effective against cancer cells that are resistant to other cancer drugs.</p>Formula:C15H16N5Na2O8P·H2OPurity:Min. 95%Color and Shape:PowderMolecular weight:489.29 g/mol
