Inhibitors

IFB-088 acetate targets PPP1R15A-related diseases, including cancers and protein misfolding disorders.

A-83586C, a depsipeptide antibiotic, combats Gram-positive bacteria, hinders beta-catenin/TCF4 in cancer, and suppresses E2F1 and pRb phosphorylation.

Purpactin A is a useful organic compound for research related to life sciences. The catalog number is T126026 and the CAS number is 133806-59-4.

PYRETHRIN is a useful organic compound for research related to life sciences and the catalog number is T126212.

Kirromycin, an antibiotic from Streptomyces, blocks protein synthesis and stunts B. brevis growth by hindering elongation factor Tu in E. coli.

GP4G, from Artemia salina cysts, regulates epithelial cells & hair growth.

Digitoxigenin is a precursor of cardiac glycosides that acts by targeting the metastatic uveal melanoma gene signature.

Phospholipid with stearic acid and 15(S)-HpETE boosts ferroptosis in MEFs upon GPX4 inhibition.

Clopidogrel Related Compound A is a useful organic compound for research related to life sciences.

(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.

Vinformide is a potent cytostatic agent.

(S)-6-methoxychroman-3-carboxylic acid is a synthetic C11H10O5 compound, part of the seven-membered ring chroman family.

1,1,1,3-Tetrachloroacetone forms ozone-chlorine and chloramine DBPs with high bromide when chlorine-treated.

"Cyclohexanoyl CoA (CHCoA) activates CHC in R. palustris, converts to hippuric acid in guinea pig liver."

Simotaxel is a semi-synthetic, orally bioavailable, third-generation taxane derivative and microtubule-stabilizing agent, with potential antineoplastic activity

Ropinirole (SKF 101468) is a D3/D2 receptor agonist with anti-amyotrophic lateral sclerosis properties.

Hexanoyl-L-carnitine is a medium-chain acylcarnitine. It has been used in the synthesis of acylcarnitine benzyl esters.1

Truncated ADR58, with 31 bases, mimics full ADR58's function, blocks OSM binding to gp130, and may aid in rheumatoid arthritis research.

4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is

Vanilmandelic acid is a precursor for synthetic vanilla flavor and a final metabolite of epinephrine and norepinephrine.

Mycalolide-B, from marine sponges, blocks actomyosin ATPase, stopping ATP-triggered contraction without Ca2+.

TLR7/8 agonist 4-PEG10-acid (compound 9) is a potent ADC linker for cancer therapy with a cleavable bond.

Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.

Tribromonitromethane is a member of the class of Halonitromethanes, a newly identified group of disinfection by-products (DBPs) found in drinking water.

4-N-Nonyloxyphenol, kaolinite nanotube photosensitizer, degrades phenolic pesticides, and disrupts endocrine.

Lycopsamine `1-acetate is a bioactive chemical.

3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).

2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).

Alphitonin: a flavonoid in L. leptolepis wood, metabolized from quercetin by E. ramulus in the gut.

Propargyl-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

CAY10606 has a wide range of applications in life science related research.

Neoaureothin, a Streptomyces metabolite, is an AR antagonist with anti-androgen and cytotoxic effects, also active against B. xylophilus.

Thyminalkamine is a biochemical.

2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.

GRKs-IN-1 HCl (14as) strongly inhibits GRK2 (IC50=130nM) & GRK5 (IC50=7.1μM), is a paroxetine derivative with 100x cardiac boost.

SIRT1 activated by CAY10591, mimics caloric restriction, extends lifespan, inhibits apoptosis, suppresses TNF-α, and promotes fat mobilization.

7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs).