Inhibitors

Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.

MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.

Limocitrol is a flavonol glycoside.

Przewaquinone C is a useful organic compound for research related to life sciences and the catalog number is T123839.

ISA-2011B-P2 is a stereoisomer of ISA-2011B, a potent PIP5K1α inhibitor with antitumor activity.

Fmoc-D-Val-D-Cit-PAB is a cleavable linker for antibody-drug-conjugation (ADC).

trans-Hydroxy Glimepiride, an active sulfonylurea glimepiride metabolite, is primarily synthesized in the liver by CYP2C9.

Sphingomyelins, 2-15% of organ phospholipids, are prevalent in brain and nerve sheaths, regulate cholesterol, and turn into ceramides by hydrolysis.

Mivorilaner is an antineoplastic compound that has shown potential for application in veterinary medicine research (WO2012155676, Example 245).

Fluometuron: herbicide approved in 1974 for cotton and sugarcane in the US; since 1986, only for cotton.

Acemannan can produce cell proliferation and skin wound healing through AKT/mTOR signaling pathway.

GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.

9(S)-HODE cholesteryl ester, from atherosclerotic lesions, has an uncertain origin and serves as a standard for chiral ester analysis.

Azadirone, a limonoid, sensitizes cancer cells to TRAIL by modulating DR4/DR5, survival, and apoptotic proteins.

Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid

D-threo-PPMP, a powerful glucosylceramide (GlcCer) synthase inhibitor, effectively impedes karyokinesis and decreases cyst formation.