Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,687 products)
- Apoptosis(6,097 products)
- Cell Cycle/Checkpoint(4,691 products)
- Chromatin/Epigenetics(2,376 products)
- Cytoskeletal Signaling(1,472 products)
- DNA Damage/DNA Repair(2,921 products)
- Endocrinology/Hormones(3,611 products)
- Enzyme(3,655 products)
- GPCR/G-Protein(8,755 products)
- Immunology and Inflammation(3,765 products)
- Influenza Virus(298 products)
- JAK/STAT signaling(407 products)
- MAPK Signaling(1,230 products)
- Membrane Transporter/Ion Channel(2,947 products)
- Metabolism(9,940 products)
- Microbiology/Virology(7,347 products)
- Neuroscience(10,240 products)
- Other Inhibitors(36,533 products)
- Oxidation-Reduction(43 products)
- PI3K/Akt/mTOR Signaling(1,437 products)
- Proteases/Proteasome(1,675 products)
- Stem Cell and Derivatives(830 products)
- Tyrosine Kinase/Adaptors(2,028 products)
- Ubiquitination(1,682 products)
Show 16 more subcategories
Found 66582 products of "Inhibitors"
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Supercinnamaldehyde
CAS:Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 of 0.8 μM, and induces activation of TRPA1 ionFormula:C12H11NO2Purity:98.89%Color and Shape:SolidMolecular weight:201.22Fluspirilene
CAS:Fluspirilene is a long-acting antipsychotic for schizophrenia, inhibiting L-type calcium channels (IC50: 0.03 μM).Formula:C29H31F2N3OPurity:99.59%Color and Shape:SolidMolecular weight:475.57Nrf2-IN-3
CAS:Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.Formula:C22H26N4O4SPurity:98.07%Color and Shape:SolidMolecular weight:442.53MMV688533
CAS:<p>MMV688533 has antimalarial activity.</p>Formula:C24H15F6N5O2Purity:99.12%Color and Shape:SoildMolecular weight:519.4Holomycin
CAS:<p>Holomycin, a dithiopyrrolidone antibiotic, promotes S2753 biofilm formation and has broad-spectrum antibacterial and antitumor properties.</p>Formula:C7H6N2O2S2Purity:98.76%Color and Shape:SoildMolecular weight:214.26KDM4-IN-4
CAS:KDM4-IN-4 is a KDM4 inhibitor with anticancer activity that inhibits the KDM4A-Tudor structural domain for cancer research.Formula:C16H23NOPurity:99.61%Color and Shape:SolidMolecular weight:245.36H-1152 dihydrochloride
CAS:<p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>Formula:C16H23Cl2N3O2SPurity:99.85%Color and Shape:SolidMolecular weight:392.34ZY-19489
CAS:<p>ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.</p>Formula:C24H32FN9Purity:>99.99%Color and Shape:SoildMolecular weight:465.57R-(+)-EU-1180-453
CAS:R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Formula:C22H21FN2O3Purity:99.63%Color and Shape:SolidMolecular weight:380.41ABR-238901
CAS:<p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>Formula:C11H9BrClN3O4SPurity:98.63% - 98.71%Color and Shape:SolidMolecular weight:394.63Ropsacitinib
CAS:Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).Formula:C20H17N9Purity:99.87%Color and Shape:SolidMolecular weight:383.41CINPA1
CAS:CINPA1 selectively inhibits CAR with IC50 of 70 nM, useful in CAR function studies.Formula:C23H29N3O3Purity:99.98%Color and Shape:SolidMolecular weight:395.49Jarin-1
CAS:Jarin-1: JAR1 inhibitor, blocks bioactive JA production in plants, IC50 3.8 μM.Formula:C28H29N3O4Purity:99.82%Color and Shape:SolidMolecular weight:471.55WAY-639889
CAS:<p>WAY-639889 is a small molecule compound with selective and potent inhibitory effects on neuropeptide Y-5 receptors.</p>Formula:C25H27N5OPurity:99.73%Color and Shape:SolidMolecular weight:413.51Xanthine oxidase-IN-1
CAS:<p>Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM.</p>Formula:C16H8F2N2O3Purity:97.36% - 99.22%Color and Shape:SolidMolecular weight:314.24Aucuparin
CAS:<p>Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity.</p>Formula:C14H14O3Purity:99.98%Color and Shape:SolidMolecular weight:230.26IN-1130
CAS:IN-1130: ALK5 inhibitor, IC50 - 5.3 nM (Smad3), 36 nM (casein), 4.3 μM (p38α MAPK).Formula:C25H20N6OPurity:99.79%Color and Shape:SolidMolecular weight:420.47Tefinostat
CAS:<p>Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor.</p>Formula:C28H37N3O5Purity:99.83%Color and Shape:SolidMolecular weight:495.61RIPK1-IN-4
CAS:<p>RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s</p>Formula:C23H23N5O2Purity:99.94%Color and Shape:SolidMolecular weight:401.46Elobixibat
CAS:Elobixibat (A 3309) blocks IBAT in mice/humans/dogs (IC50: 0.13/0.53/5.8 nM); used for constipation research.Formula:C36H45N3O7S2Purity:97.43% - 98.03%Color and Shape:SolidMolecular weight:695.89PAOPA
CAS:dopamine D2 receptor modulatorFormula:C11H18N4O3Purity:>99.99%Color and Shape:SolidMolecular weight:254.29Ifebemtinib
CAS:Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Formula:C28H28F4N6O4Purity:98.84% - 99.85%Color and Shape:SolidMolecular weight:588.55TAK-441
CAS:TAK-441: oral Hedgehog signal blocker, potent anticancer, IC50=4.4 nM, reduces Gli1 mRNA & tumor growth.Formula:C28H31F3N4O6Purity:99.82%Color and Shape:SolidMolecular weight:576.56Ac-DEVD-CHO
CAS:Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM).Ac-DEVD-CHO has an inhibitory effect in SLNT-induced apoptosis.Formula:C20H30N4O11Purity:98.69%Color and Shape:SolidMolecular weight:502.47Reldesemtiv
CAS:<p>Reldesemtiv (CK-2127107) boosts exercise capacity, targeting fast muscle troponin, EC50 3.4 μM.</p>Formula:C19H18F2N6OPurity:97.27%Color and Shape:SolidMolecular weight:384.38Bupivacaine hydrochloride monohydrate
CAS:Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.Formula:C18H31ClN2O2Purity:99.91%Color and Shape:SolidMolecular weight:342.9ATM-3507
CAS:ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.Formula:C37H46FN5O2Purity:96.77% - 98.81%Color and Shape:SolidMolecular weight:611.79INCB3344
CAS:INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8Formula:C29H34F3N3O6Purity:98% - 98.2%Color and Shape:SolidMolecular weight:577.59MK-8353
CAS:MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)Formula:C37H41N9O3SPurity:96.15% - 97.19%Color and Shape:SolidMolecular weight:691.84Sorivudine
CAS:Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.Formula:C11H13BrN2O6Purity:99.74%Color and Shape:SolidMolecular weight:349.13CeMMEC1
CAS:CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).Formula:C19H16N2O4Purity:98.9% - 99.92%Color and Shape:SolidMolecular weight:336.34PKC-IN-1
CAS:PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Formula:C25H37FN8O2Purity:98% - 98.79%Color and Shape:SolidMolecular weight:500.61AMG2850
CAS:AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).Formula:C19H17F6N3OPurity:99.84%Color and Shape:SolidMolecular weight:417.35PF-04979064
CAS:<p>PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).</p>Formula:C24H26N6O3Purity:98.20% - ≥98%Color and Shape:SolidMolecular weight:446.5Mutant IDH1-IN-2
CAS:Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-Formula:C24H31F2N5O2Purity:99.88%Color and Shape:SolidMolecular weight:459.53PKI-402
CAS:PKI-402 is a potent PI3K and mTOR inhibitor. PKI-402 inhibits PI3Kα, mTOR, PI3Kβ, PI3Kδ and PI3Kγ with IC50s of 2, 3, 7, 14 and 16 nM, respectively.Formula:C29H34N10O3Purity:99.94%Color and Shape:SolidMolecular weight:570.65PXS-5120A
CAS:<p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>Formula:C22H25ClFN3O4SPurity:97.02%Color and Shape:SolidMolecular weight:481.97VBY-825
CAS:VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.Formula:C23H29F4N3O5SPurity:99.91%Color and Shape:SolidMolecular weight:535.55SR 142948
CAS:<p>SR 142948 is a neurotensin (NT) receptor antagonist.</p>Formula:C39H51N5O6Purity:98%Color and Shape:SolidMolecular weight:685.85PSB 1115
CAS:PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.Formula:C14H14N4O5SPurity:98.69% - >99.99%Color and Shape:SolidMolecular weight:350.35Lomibuvir
CAS:<p>Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.</p>Formula:C25H35NO4SPurity:99.83%Color and Shape:SolidMolecular weight:445.61EGFR-IN-8
CAS:<p>EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC</p>Formula:C32H23ClF3N7O4Purity:99.51%Color and Shape:SolidMolecular weight:662.02SB-616234-A
CAS:SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Formula:C32H36ClN5O3Purity:99.72%Color and Shape:SolidMolecular weight:574.11AZ-23
CAS:AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C.Formula:C17H19ClFN7OPurity:99.4%Color and Shape:SolidMolecular weight:391.83HM43239
CAS:HM43239: oral FLT3 inhibitor; IC50: FLT3 WT 1.1nM, ITD 1.8nM, D835Y 1.0nM; blocks p-STAT5/p-ERK; affects SYK, JAK1/2, TAK1; halts leukemia cell growth.Formula:C29H33ClN6Purity:99.7%Color and Shape:SolidMolecular weight:501.07GSK-3 inhibitor 1
CAS:GSK-3 inhibitor 1 is a GSK-3 inhibitor.Formula:C22H17ClFN5O2Purity:98.42%Color and Shape:SolidMolecular weight:437.85GDC-0349
CAS:<p>GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.</p>Formula:C24H32N6O3Purity:96.00% - 98.17%Color and Shape:SolidMolecular weight:452.55MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Formula:C20H22O4Purity:98.57%Color and Shape:SolidMolecular weight:326.39GSK-F1
CAS:GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor.Formula:C27H18F5N5O4SPurity:97.03%Color and Shape:SolidMolecular weight:603.52Src Inhibitor 3
CAS:Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Formula:C34H32ClFN8O4Purity:98.35%Color and Shape:SolidMolecular weight:671.12BMS-986176
CAS:<p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>Formula:C19H23F4N3OPurity:98.58% - 98.7%Color and Shape:SolidMolecular weight:385.4AMG 837 calcium hydrate
CAS:<p>AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM.</p>Formula:C52H44CaF6O8Purity:98.07%Color and Shape:SolidMolecular weight:950.97Pan-RAS-IN-1
CAS:Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.Formula:C36H41Cl2F3N6O2Purity:99.77%Color and Shape:SolidMolecular weight:717.65CAY10781
CAS:<p>CAY10781 inhibits NRP-1/VEGF-A binding by 43% at 12.5μM and blocks VEGFR2 phosphorylation in CAD cells.</p>Formula:C11H9N3O3Purity:99.49%Color and Shape:SolidMolecular weight:231.21Y06137
CAS:<p>Y06137, selective BET inhibitor, Kd 81 nM for BRD4(1), researched for castration-resistant prostate cancer treatment.</p>Formula:C27H32N4O2Purity:99.85%Color and Shape:SolidMolecular weight:444.57PXS-5153A
CAS:PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.Formula:C20H25Cl2FN4O2SPurity:99.58%Color and Shape:SolidMolecular weight:475.41Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formula:C24H28FN3OPurity:99.68% - 99.91%Color and Shape:SolidMolecular weight:393.5Plumbemycin B
CAS:Plumbemycin B is isolated from Streptomyces plumbeus; an L-threonine antagonist.Formula:C12H21N4O8PColor and Shape:SolidMolecular weight:380.29D6808
D6808: selective c-Met inhibitor, IC50=2.9 nM, induces apoptosis and cell cycle arrest, for NSCLC/gastric cancer research.Formula:C30H25F3N6O2Color and Shape:SolidMolecular weight:558.55Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19PDHK-IN-4
PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.Formula:C24H25N5O3Color and Shape:SolidMolecular weight:431.49HER2-IN-10
HER2-IN-10 is a psoralen derivative that induces apoptosis. HER2-IN-10 shows anti-breast cancer activity and light-activated cytotoxicity [1].Formula:C15H13NO5Color and Shape:SolidMolecular weight:287.27Dyrk1A-IN-1
Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.Formula:C23H20N4O3SColor and Shape:SolidMolecular weight:432.49Cathepsin C-IN-5
CAS:<p>Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.</p>Formula:C21H17ClN6OSColor and Shape:SolidMolecular weight:436.92(RS)-AMPA hydrobromide
CAS:AMPAR agonistFormula:C7H11BrN2O4Purity:98%Color and Shape:SolidMolecular weight:267.08Vimirogant hydrochloride
Vimirogant (VTP-43742) HCl: Oral, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM), >1000x selectivity over RORα/β, targets Th17, not Th1/2/Treg.Formula:C27H36ClF3N4O3SColor and Shape:SolidMolecular weight:588.21487Dup-714
CAS:Dup-714 is a thrombin inhibitor.Formula:C21H33BN6O5Purity:98%Color and Shape:SolidMolecular weight:460.33VDR agonist 1
CAS:Compound 28 is a nonsteroidal VDR agonist with 690 nM potency, inducing cell cycle arrest and apoptosis in MCF-7 cells.Formula:C32H51N3O2Purity:98%Color and Shape:SolidMolecular weight:509.77PARP-1-IN-1
<p>PARP-1-IN-1: Selective, oral PARP-1 inhibitor with 0.96 nM IC50; well-tolerated and effective in single-dose MDA-MB-436 model.</p>Formula:C23H25FN4OColor and Shape:SolidMolecular weight:392.47PPO-IN-1
PPO-IN-1 is a potent inhibitor of protoporphyrinogen IX oxidase (PPO) (Ki: 2.5 nM).Formula:C18H10F3N3O4SColor and Shape:SolidMolecular weight:421.35(-)-Cevimeline hydrochloride hemihydrate
(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78D4R antagonist-1
<p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>Formula:C21H25F2NO2Color and Shape:SolidMolecular weight:361.43MA242
CAS:MA242 is a nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy and dual inhibitor of murine double minute 2 (MDM2).Formula:C26H21ClF3N3O5SPurity:98%Color and Shape:SolidMolecular weight:579.98L-I-OddU
CAS:<p>L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).</p>Formula:C8H9IN2O5Color and Shape:SolidMolecular weight:340.07KRAS G12D inhibitor 12
KRAS G12D inhibitor 12 targets Ras protein for cancer research. (Patent WO2021108683A1, Compound 134)Formula:C23H21ClFN5O3Color and Shape:SolidMolecular weight:469.9PNU-248686A
CAS:PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).Formula:C22H18ClNaO5S2Purity:98%Color and Shape:SolidMolecular weight:484.95LY 292728
CAS:LY 292728 is a highly potent antagonist of leukotriene B4 receptor.Formula:C34H29FO9Purity:98%Color and Shape:SolidMolecular weight:600.59Dicetrorelix pamoate
CAS:Cetrorelix pamoate is a synthetic decapeptide that acts as a GnRH antagonist, inhibiting the release of LH and FSH from the pituitary.Formula:C163H200Cl2N34O34Color and Shape:SolidMolecular weight:3250.4920-HEDE
CAS:20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.Formula:C20H36O3Purity:98%Color and Shape:SolidMolecular weight:324.50KRAS inhibitor-8
CAS:KRAS inhibitor-8 is a potent KRAS G12C inhibitor.Formula:C26H24ClF4N5O3Purity:98%Color and Shape:SolidMolecular weight:565.952,3-dinor-11β-Prostaglandin F2α
CAS:2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, whereFormula:C18H30O5Color and Shape:SolidMolecular weight:326.43COX-1/2-IN-2
COX-1/2-IN-2, a potent dual inhibitor, has IC50s: COX-1 at 9.7μM & COX-2 at 4.6μM.Formula:C15H10ClIN2OColor and Shape:SolidMolecular weight:396.61MT-134
MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.Formula:C19H16N4O3Color and Shape:SolidMolecular weight:348.36L-threo-Sphingosine C-18
CAS:L-threo-Sphingosine C-18 is a protein kinase C inhibitor.Formula:C18H37NO2Purity:98%Color and Shape:SolidMolecular weight:299.49PDE4B/7A-IN-1
CAS:5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.Formula:C25H35N3O3Color and Shape:SolidMolecular weight:425.56RORγt inverse agonist 29
RORγt inverse agonist 29 is a potent, selective, orally active RORγt inverse agonist with an IC50 value of 21 nM.Formula:C25H24N2O5SColor and Shape:SolidMolecular weight:464.53Fostriecin (free base)
CAS:Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Formula:C19H27O9PColor and Shape:SolidMolecular weight:430.39HER2-IN-9
<p>HER2-IN-9, an oral HER2 inhibitor (IC50: 0.03 μM), hinders growth and spread of HER2+ breast cancer.</p>Formula:C19H14BrF3N2OColor and Shape:SolidMolecular weight:423.23EGFR/HER2-IN-8
EGFR/HER2-IN-8 inhibits EGFR, HER2, DHFR (IC50: 0.45, 0.244, 5.669 μM); useful in cancer research, safe and selective.Formula:C16H16N4O2SColor and Shape:SolidMolecular weight:328.398(S),15(S)-DiHETE
CAS:<p>8(S),15(S)-DiHETE, from 15(S)-HETE's oxidation by 15-LO, triggers eosinophil movement at 1.5 μM; it counteracts pain and LTB4 effects.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47KRAS G12C inhibitor 44
KRAS G12C inhibitor 44: potent, oral, anti-cancer; halts cell growth in MIA PaCA-2, H358; effective in vivo. IC50: MIA-0.016μM, H358-0.028μM.Formula:C31H36ClFN6O2Color and Shape:SolidMolecular weight:579.11MAFP
CAS:MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.Formula:C21H36FO2PColor and Shape:SolidMolecular weight:370.48Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.672R,4S-Sacubitril
CAS:<p>2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.</p>Formula:C24H28NO51CaPurity:98%Color and Shape:SolidMolecular weight:430.49SP-471
SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.Formula:C33H26BrN5Color and Shape:SolidMolecular weight:572.5BIIE-0246 HCl
CAS:BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.Formula:C49H59Cl2N11O6Color and Shape:SolidMolecular weight:968.972-Methylsorbinol
CAS:2-Methylsorbinol is a bioactive chemical.Formula:C12H11FN2O3Color and Shape:SolidMolecular weight:250.23PTP1B-IN-19
<p>PTP1B-IN-19, a benzimidazole, selectively inhibits protein tyrosine phosphatase 1B with a Ki of 23.3 μM, potential for type 2 diabetes research.</p>Formula:C26H19N3O4SColor and Shape:SolidMolecular weight:469.51AR antagonist 4
<p>AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).</p>Formula:C29H36N4OColor and Shape:SolidMolecular weight:456.62TAK-024
CAS:TAK-024 is an inhibitor of platelet(IC50s of 31, 79 and 51 nM in human, monkey and guinea pig, respectively).Formula:C27H34N10O6Purity:98%Color and Shape:SolidMolecular weight:594.62AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Formula:C32H35ClN6O3Color and Shape:SolidMolecular weight:587.11DC4SMe
CAS:<p>DC4SMe, a prodrug for targeted tumor therapy and ADC synthesis, has IC50s: 1.9 nM (Ramos), 2.9 nM (Namalwa), 1.8 nM (HL60/s).</p>Formula:C35H31ClN5O7PS2Purity:98%Color and Shape:SolidMolecular weight:764.21IRAK4-IN-12
IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 (IC50: 0.015 μM) with cellular pIRAK4 potency (IC50: 0.5 μM).Formula:C24H31FN8OColor and Shape:SolidMolecular weight:466.55ERK1/2 inhibitor 6
CAS:ERK1/2 inhibitor 6 - potent cancer/inflammation treatment from WO2021063335A1.Formula:C27H29ClFN7O5Color and Shape:SolidMolecular weight:586.01LY 178210
CAS:LY 178210 is a 5-hydroxytryptamine receptor agonist.Formula:C18H25N3OColor and Shape:SolidMolecular weight:299.419(S)-HETE
CAS:<p>9(S)-HETE is an enantiomer of (±)9-HETE, not an enzymatic product, and doesn't promote cell adhesion like 12(S)-HETE. Identified by chiral HPLC.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47RET-IN-14
CAS:RET-IN-14 inhibits RET (IC50: <0.51-9.3 nM) & BTK (C481S) (IC50: 9.2-15 nM), promising for tumor research.Formula:C24H23FN8O4Color and Shape:SolidMolecular weight:506.49L-Moses dihydrochloride
<p>L-Moses (L-45) dihydrochloride is the first, potent, selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor (Kd: 126 nM).</p>Formula:C21H26Cl2N6Color and Shape:SolidMolecular weight:433.38LRRK2-IN-5
LRRK2-IN-5 is an oral, BBB-penetrating selective inhibitor for LRRK2 with IC50s: 1.2μM (GS) and 16μM (WT); halts LRRK2 autophosphorylation.Formula:C24H26F2N4O2SColor and Shape:SolidMolecular weight:472.55MI-1851
CAS:<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Formula:C34H53N15O6Color and Shape:SolidMolecular weight:767.88Autophagy-IN-1
Autophagy-IN-1 blocks autophagy in cancer cells, hinders tumor growth in mice, and aids in studying colorectal cancer.Formula:C23H25NO7Color and Shape:SolidMolecular weight:427.45Antibacterial agent 112
Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.Formula:C35H23N5O5Color and Shape:SolidMolecular weight:593.59(±)-J 113397
CAS:(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).Formula:C24H37N3O2Color and Shape:SolidMolecular weight:399.57GLP-1R agonist 8
CAS:<p>GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).</p>Formula:C33H32N4O5Color and Shape:SolidMolecular weight:564.63Isobetanin
CAS:<p>Isobetanin is a betacyanin that has been shown to enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells.</p>Formula:C24H26N2O13Color and Shape:SolidMolecular weight:550.47SARS-CoV-2-IN-6
SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.Formula:C17H13ClN2O2Color and Shape:SolidMolecular weight:312.75ETP-47037
CAS:ETP-47037: strong PI3Kα inhibitor (IC50: 0.99 nM), also targets PI3Kβ, δ, γ; may protect telomeres.Formula:C20H27N9O3SColor and Shape:SolidMolecular weight:473.55Metesind Glucuronate
CAS:Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.Formula:C29H34N4O10SColor and Shape:SolidMolecular weight:630.67Moflomycin
CAS:Moflomycin is an anthracycline derivative. It exhibits a higher antileukemic activity compared to other anthracyclines.Formula:C25H25IO10Purity:98%Color and Shape:SolidMolecular weight:612.36GSK065
CAS:GSK065 is a potent inhibitor of kynurenine-3-monooxygenase (KMO).Formula:C17H15ClN2O4Color and Shape:SolidMolecular weight:346.77LX2761
CAS:LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.Formula:C32H47N3O6SPurity:98%Color and Shape:SolidMolecular weight:601.80Lisuride
CAS:Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Formula:C20H26N4OColor and Shape:SolidMolecular weight:338.45KH-259
KH-259: potent, selective CNS-penetrant HDAC6 inhibitor with 0.26 μM IC50; shows antidepressant effects in mice.Formula:C20H25N3O2Color and Shape:SolidMolecular weight:339.43Leustroducsin B
CAS:Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.Formula:C34H56NO10PColor and Shape:SolidMolecular weight:669.78WM382
CAS:<p>WM382, a potent dual PMIX/X inhibitor, has IC50s of 1.4 nM/0.03 nM and effective against various malaria stages.</p>Formula:C29H36N4O4Color and Shape:SolidMolecular weight:504.62AS2521780
CAS:AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).Formula:C30H41N7OSPurity:98%Color and Shape:SolidMolecular weight:547.76ACT-672125
CAS:ACT-672125: Potent CXCR3 blocker, may treat autoimmunity, safe with dose-dependent efficacy in lung inflammation.Formula:C25H25F3N10O2SColor and Shape:SolidMolecular weight:586.59Methyl Streptonigrin
CAS:Methyl Streptonigrin is an ABCG2 transporter function inhibitor.Formula:C26H24N4O8Purity:98%Color and Shape:SolidMolecular weight:520.49TRPC5-IN-4
CAS:<p>TRPC5-IN-4: Potent, safe inhibitor; IC50 14.07 nM (TRPC5), 65 nM (TRPC4); non-toxic to liver/kidney cells; for CKD research.</p>Formula:C18H11ClF4N4O3Color and Shape:SolidMolecular weight:442.75BRD4 D1-IN-1
BRD4 D1-IN-1 selectively inhibits BRD4 D1 (IC50 <0.092 μM, Kd 18 nM) with >500-fold specificity versus D2.Formula:C32H37F3N6OColor and Shape:SolidMolecular weight:578.67Antitumor agent-43
Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase.Formula:C16H8N2O3Color and Shape:SolidMolecular weight:276.25DYRK1-IN-1
CAS:<p>DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.</p>Formula:C12H12N6Color and Shape:SolidMolecular weight:240.26Carazostatin
CAS:Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor.Formula:C20H25NOPurity:98%Color and Shape:Pale Yellow SolidMolecular weight:295.42Sargachromanol E
CAS:<p>Sargachromanol E is a compound isolated from the marine brown alga, Sargassum horneri. It has been studied for its inhibitory effect on skin ageing.</p>Formula:C27H40O4Color and Shape:SolidMolecular weight:428.6Anti-TSWV agent 1
<p>Anti-TSWV agent 1 is a highly effective inactivator (EC50:144 μg/mL) of tomato spotted wilt virus (TSWV).</p>Formula:C22H27ClN4OS3Color and Shape:SolidMolecular weight:495.12DSP-6952
CAS:DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.Formula:C21H32BrClN4O5Color and Shape:SolidMolecular weight:535.86NU5455
CAS:<p>NU5455 is a potent DNA-PKcs inhibitor, oral, boosts doxorubicin in liver tumors, amplifies topoisomerase inhibitors, no adverse effects.</p>Formula:C34H33N3O5SColor and Shape:SolidMolecular weight:595.71PF-06751979
CAS:PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).Formula:C18H19F2N5O3S2Purity:98%Color and Shape:SolidMolecular weight:455.5M-525
CAS:M-525, a potent first-in-class menin-MLL inhibitor, binds at 3 nM IC50 and curbs MLL leukemia cell growth & gene expression.Formula:C39H51FN6O5SPurity:98%Color and Shape:SolidMolecular weight:734.92UK-370106
CAS:<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Formula:C35H44N2O5Purity:98%Color and Shape:SolidMolecular weight:572.73ZD6021
CAS:ZD6021 is an antagonist of neurokinin 1 receptor.Formula:C35H35Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:632.64Pateamine A
CAS:Pateamine A: marine-sourced macrolide from Mycale hentscheli; anticancer, antiviral, and translation inhibitor.Formula:C31H45N3O4SColor and Shape:SolidMolecular weight:555.77Cas9-IN-1
Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.Formula:C17H11Cl2F3N2O3SColor and Shape:SolidMolecular weight:451.25P-gp modulator 3
<p>P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.</p>Formula:C31H37N3O5Color and Shape:SolidMolecular weight:531.64PI3K-IN-37
CAS:PI3K-IN-37 inhibits PI3K α/β/δ (IC50: 6/8/4 nM) and mTOR (IC50: 4 nM).Formula:C25H26N6O2Color and Shape:SolidMolecular weight:442.51Flurdihydroergotamine
CAS:Flurdihydroergotamine, a serotonin 5HT1 receptor agonist, is used as an antimigraine drug.Formula:C34H36F3N5O5Purity:98%Color and Shape:SolidMolecular weight:651.681,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5GLS1 Inhibitor-5
<p>GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.</p>Color and Shape:SolidLu 26-046
CAS:Lu 26-046 is a muscarinic receptor agonist.Formula:C10H12N2OSColor and Shape:SolidMolecular weight:208.28COX-2/PI3K-IN-2
<p>COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).</p>Formula:C16H17N5O2Color and Shape:SolidMolecular weight:311.34Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Formula:C15H17N3O3SColor and Shape:SolidMolecular weight:319.38GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Formula:C24H21N3O5SColor and Shape:SolidMolecular weight:463.51Irinotecan Carboxylate Sodium Salt
CAS:Irinotecan Carboxylate Sodium Salt is a DNA topoisomerase inhibitor.Formula:C33H39N4NaO7Color and Shape:SolidMolecular weight:626.68ZBH-1205
CAS:<p>ZBH-1205, a camptothecin derivative, shows strong antitumor effects via apoptosis, outperforming cpt-11 and sn38 in topoisomerase-1 inhibition.</p>Formula:C29H31N3O8Color and Shape:SolidMolecular weight:549.57Omaciclovir
CAS:Omaciclovir (ABT-091) is a herpesvirus herpesvirus replication inhibitor with antiviral activity that is used in the study of herpesvirus infections.Formula:C10H15N5O3Purity:99.46% - 99.46%Color and Shape:SolidMolecular weight:253.26Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Formula:C20H12ClN3O5Color and Shape:SolidMolecular weight:409.78Antitumor agent-47
Antitumor agent-47, a silibinin derivative, shows cytotoxicity in NCI-H1299 (IC50: 8.07µM) and HT29 (IC50: 6.27µM) cells.Formula:C30H27NO11Color and Shape:SolidMolecular weight:577.54Anticancer agent 80
Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).Formula:C19H12BrNO5Color and Shape:SolidMolecular weight:414.21Anticancer agent 54
Anticancer agent 54 blocks cell cycle in G0/G1, induces apoptosis, and fights cancer via DNA embedding and ROS.Formula:C33H36N6Color and Shape:SolidMolecular weight:516.68PARP1-IN-5
<p>PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.</p>Formula:C25H24N2O5SColor and Shape:SolidMolecular weight:464.53Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Formula:C18H16Br2O2Color and Shape:SolidMolecular weight:424.13Ketomethylenebestatin
CAS:Ketomethylenebestatin, a weaker carba-analog of aminopeptidase inhibitor bestatin, is 10x less potent.Formula:C17H25NO4Purity:98%Color and Shape:SolidMolecular weight:307.38EGFR-IN-35
CAS:EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.Formula:C25H24ClN7O2Color and Shape:SolidMolecular weight:489.96SphK1-IN-1
<p>SphK1-IN-1: SphK1 ATPase inhibitor, IC50=2.48 μM, potential for cancer research.</p>Formula:C22H22N6O2Color and Shape:SolidMolecular weight:402.45AZD-4121 tert-butylammonium
CAS:AZD-4121 tert-butylammonium is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.Formula:C40H50F2N4O7SColor and Shape:SolidMolecular weight:768.91PROTAC FKBP Degrader-3
CAS:PROTAC FKBP Degrader-3, with FKBP and VHL binding groups linked, is a potent FKBP degrader.Formula:C68H90N6O17SPurity:98%Color and Shape:SolidMolecular weight:1295.54HPK1-IN-16
CAS:HPK1-IN-16, a potent HPK1 inhibitor, useful for cancer research and treatment.Formula:C28H27FN4OColor and Shape:SolidMolecular weight:454.54CDK1-IN-5
CDK1-IN-5 is a selective inhibitor for CDK1 (IC50: 42.19 nM), CDK2, CDK5, halting cancer cell growth.Formula:C27H26ClN5OSColor and Shape:SolidMolecular weight:504.05YCW-E11
CAS:<p>YCW-E11 is an antiapoptotic Bcl-2 family proteins inhibitor.</p>Formula:C25H21Cl2N3O6S2Purity:98%Color and Shape:SolidMolecular weight:594.49Antitumor agent-51
Antitumor agent-51 targets osteosarcoma with 21.9 nM IC50, high selectivity, and low toxicity.Formula:C23H25N5O2SColor and Shape:SolidMolecular weight:435.54Gly-7-MAD-MDCPT
CAS:<p>Gly-7-MAD-MDCPT: anticancer Camptothecin with IC50 of 10-1000 nM against diverse cancers.</p>Formula:C24H22N4O7Color and Shape:SolidMolecular weight:478.45ZLMT-12
<p>ZLMT-12: tacrine derivative, inhibits CDK2/CDK9, weak on AChE/BuChE, anti-proliferative, low toxicity, blocks S/G2/M phase, induces apoptosis.</p>Formula:C26H31ClN6OColor and Shape:SolidMolecular weight:479.02AMXI-5001 hydrochloride
<p>AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.</p>Formula:C25H21ClFN5O3Color and Shape:SolidMolecular weight:493.92SSR 146977
CAS:NK3 receptor antagonistFormula:C35H42Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:621.64Ici D1542
CAS:Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formula:C25H30N2O7Purity:98%Color and Shape:SolidMolecular weight:470.51Triciferol
CAS:Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.Formula:C26H39NO4Color and Shape:SolidMolecular weight:429.591RSV-IN-5
CAS:<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formula:C28H37N7O2Color and Shape:SolidMolecular weight:503.64SK&F 108361
CAS:SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.Formula:C24H48N6O6Color and Shape:SolidMolecular weight:516.67SphK2-IN-1
CAS:<p>SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.</p>Formula:C23H22ClF3N8OColor and Shape:SolidMolecular weight:518.92Vulolisib
CAS:<p>Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.</p>Formula:C18H19F2N5O3SColor and Shape:SolidMolecular weight:423.44MrgprX2 antagonist-7
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.Formula:C24H22ClF3N6O3Color and Shape:SolidMolecular weight:534.92Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formula:C7H14N3NaO8SColor and Shape:SolidMolecular weight:323.26XPO1-IN-1
XPO1-IN-1: an oral MM.1S cell inhibitor (IC50: 24 nM), induces apoptosis, stable metabolism, good pharmacokinetics.Formula:C20H15F6N5O3SColor and Shape:SolidMolecular weight:519.42Dyrk1A-IN-4
CAS:Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.Formula:C14H13F3N6Color and Shape:SolidMolecular weight:322.29MV061194
CAS:MV061194 is a potent and selective cathepsin K (Cat K) inhibitor.Formula:C28H37N5O4SColor and Shape:SolidMolecular weight:539.69Antioxidant agent-3
Antioxidant agent-3 shows strong DPPH and ABTS+ radical scavenging (IC50: 26.58, 30.31 μM). Boosts ROS, SOD, GSH; lowers LDH in H2O2-exposed HepG2 cells.Formula:C18H14O8Color and Shape:SolidMolecular weight:358.3TY 11345
CAS:<p>TY 11345 is a proton pump inhibitor.</p>Formula:C18H18N3NaO2SColor and Shape:SolidMolecular weight:363.41Antioxidant agent-8
<p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.</p>Formula:C13H12O5Color and Shape:SolidMolecular weight:248.23PLP_Snyder530
PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46CXCR2 antagonist 6
CXCR2 antagonist 6: strong CXCR2 affinity (IC50=0.044 μM), hinders calcium mobilization (IC50=0.66 μM).Formula:C17H16F2N4OSColor and Shape:SolidMolecular weight:362.4Tubulin polymerization-IN-9
CAS:Tubulin-IN-9 inhibits tubulin (IC50: 1.82 μM), halts K562 cells in G2/M, induces apoptosis, and has anti-cancer effects.Formula:C19H19NO5SeColor and Shape:SolidMolecular weight:420.32Aniline-MPB-amino-C3-PBD
CAS:Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent.Formula:C42H46N8O6Purity:98%Color and Shape:SolidMolecular weight:758.86MRS2279
CAS:Selective, high affinity competitive antagonist of the P2Y1 receptorFormula:C13H18ClN5O8P2Purity:98%Color and Shape:SolidMolecular weight:469.71BAY-899
CAS:BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.Formula:C25H19F2N5O2Purity:98%Color and Shape:SolidMolecular weight:459.45Rostratin B
CAS:Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.Formula:C18H20N2O6S2Color and Shape:SolidMolecular weight:424.49BChE-IN-5
BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.Formula:C30H42N4OColor and Shape:SolidMolecular weight:474.68FLT3/TrKA-IN-1
FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56URAT1 inhibitor 3
URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.Formula:C14H8Cl2N2O2Color and Shape:SolidMolecular weight:307.13NBTIs-IN-5
CAS:NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48
