Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,850 products)
- Apoptosis(6,367 products)
- Cell Cycle/Checkpoint(4,909 products)
- Chromatin/Epigenetics(2,631 products)
- Cytoskeletal Signaling(1,586 products)
- DNA Damage/DNA Repair(2,868 products)
- Endocrinology/Hormones(3,765 products)
- Enzyme(3,673 products)
- GPCR/G-Protein(9,053 products)
- Immunology and Inflammation(3,946 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(417 products)
- MAPK Signaling(1,259 products)
- Membrane Transporter/Ion Channel(3,163 products)
- Metabolism(10,156 products)
- Microbiology/Virology(7,671 products)
- Neuroscience(10,551 products)
- Other Inhibitors(35,855 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,435 products)
- Proteases/Proteasome(1,692 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,989 products)
- Ubiquitination(1,744 products)
Show 16 more subcategories
Found 66515 products of "Inhibitors"
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SARS-CoV-2 3CLpro-IN-2
CAS:SARS-CoV-2 3CLpro-IN-2 is a potent inhibitor of the 3CL protease pair and has shown research potential for SARS-CoV-2 disease.Formula:C21H18F5N5O4Color and Shape:SolidMolecular weight:499.39ZINC475239213
CAS:ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 μM [1].Formula:C21H15N5O2Purity:98%Color and Shape:SolidMolecular weight:369.38Ro 41-5253
CAS:Ro 41-5253 is a RARα antagonist with antitumor activity that inhibits the proliferation of ZR-75.1 estrogen receptor-positive breast cancer cells.Formula:C28H36O5SPurity:98%Color and Shape:SolidMolecular weight:484.65MRS1505
CAS:MRS1505 is a bioactive chemical.Formula:C23H28ClNO3SColor and Shape:SolidMolecular weight:433.99SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Formula:C25H28N4O5SColor and Shape:SolidMolecular weight:496.58Embramine hydrochloride
CAS:Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].Formula:C18H23BrClNOColor and Shape:SolidMolecular weight:384.74l-Primaquine
CAS:l-Primaquine is used to treat and prevent malaria and to treat Pneumocystis pneumonia.Formula:C15H21N3OColor and Shape:SolidMolecular weight:259.35PLK1/BRD4-IN-1
CAS:PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).Formula:C31H43N9O2Color and Shape:SolidMolecular weight:573.73β-cyano-L-Alanine
CAS:β-cyano-L-Alanine (Beta-cyano-l-alanine) is a nitrile of widespread occurrence in higher plants.Formula:C4H6N2O2Purity:99.86% - 99.92%Color and Shape:SolidMolecular weight:114.1Aminooxy CatB-LXR
CAS:Compound 10, Aminooxy CatB-LXR, constitutes an agent-linker conjugate for antibody-drug conjugates (ADC) [1].Formula:C52H66F3N7O11SColor and Shape:SolidMolecular weight:1054.18K-Ras G12C-IN-2
CAS:K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.Formula:C21H27ClN4O3Purity:98%Color and Shape:SolidMolecular weight:418.92NWP-0476
CAS:NWP-0476 is a modified BCL-2/BCL-xL inhibitor with enhanced specificity for BCL-xL, suitable for research on relapsed T-acute lymphoblastic leukemia (T-ALL) [1Formula:C47H53ClN8O8SColor and Shape:SolidMolecular weight:925.49IDP-73152
CAS:IDP-73152 is a peptide deformylase inhibitor.Formula:C28H41F3N4O4Color and Shape:SolidMolecular weight:554.64SUCNR1-IN-1
CAS:SUCNR1-IN-1 (Compound 20) serves as a potent SUCNR1 inhibitor, exhibiting an IC50 of 88 nM against hSUCNR1.Formula:C26H22ClF3N2O4Color and Shape:SolidMolecular weight:518.91Lp-PLA2-IN-9
CAS:Lp-PLA2-IN-9, a tetracyclic pyrimidinone, inhibits rhLp-PLA2 (pIC50: 10.1), promising for neurodegenerative research.Formula:C25H19ClF5N3O4Color and Shape:SolidMolecular weight:555.88(2,4-Dichloro-3,5-dimethoxyphenyl) methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside
CAS:(2,4-Dichloro-3,5-dimethoxyphenyl) methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside, an anticancer agent, inhibits A549 lung cancer cell proliferation with anFormula:C21H30Cl2O13Color and Shape:SolidMolecular weight:561.36PIM1-IN-1
CAS:PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it has anti-cancer properties.Formula:C25H30N8O2Purity:98.59%Color and Shape:SolidMolecular weight:474.56Uplarafenib
CAS:Uplarafenib (B-Raf IN 10), a potent BRAF inhibitor (IC50: 50-100 nM), exhibits antitumor effects on solid cancers.Formula:C22H21F3N4O4SPurity:99.98%Color and Shape:SolidMolecular weight:494.49Ref: TM-T63333
1mg54.00€5mg119.00€1mL*10mM (DMSO)131.00€10mg170.00€25mg359.00€50mg538.00€100mg928.00€JAK-IN-25
CAS:JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3.Formula:C19H17N5O4Purity:98%Color and Shape:SolidMolecular weight:379.37Glucocorticoid receptor-IN-1
CAS:Glucocorticoid receptor-IN-1 selectively modulates GR with anti-inflammatory effects, represses hMMP1 (IC50: 2.11 nM), and activates MMTV (EC50: 5.59 nM).Formula:C24H19F4N7O2Color and Shape:SolidMolecular weight:513.45(-)-Indolactam V
CAS:(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.Formula:C17H23N3O2Purity:98%Color and Shape:SolidMolecular weight:301.38CP-96021 hydrochloride
CAS:CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).Formula:C29H22ClFN4OSPurity:98%Color and Shape:SolidMolecular weight:529.03Duostatin 5
CAS:Duostatin 5 (Duo-5) is a sea hare toxin analog commonly used in the synthesis of ADC compounds.Formula:C40H69N9O6Purity:96.98%Color and Shape:SolidMolecular weight:772.03Ref: TM-T77841
1mg54.00€5mg114.00€1mL*10mM (DMSO)142.00€10mg167.00€25mg313.00€50mg528.00€100mg848.00€UHDBT
CAS:UHDBT acts as an inhibitor of the cytochrome bc1 complex Qo site, utilized in electron transfer research [1].Formula:C18H25NO3SColor and Shape:SolidMolecular weight:335.46JNJ4796
CAS:JNJ4796 is an oral fusion inhibitor that neutralizes influenza A group 1 by blocking HA-mediated fusion, mimicking bnAbs.Formula:C28H27N9O3Purity:98%Color and Shape:SolidMolecular weight:537.57PF-05150122
CAS:PF-05150122 is a novel potent and selective human Nav1.7 blocker.Formula:C24H21ClN6O3S2Purity:99.95%Color and Shape:SolidMolecular weight:541.04YM-08
CAS:YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it acts as an inhibitor of Hsp70 [1].Formula:C19H17N3OS2Purity:98%Color and Shape:SolidMolecular weight:367.49CARM1-IN-3
CAS:CARM1-IN-3 (compound 17b) is a potent, selective inhibitor of co-activator associated arginine methyltransferase (CARM1), exhibiting IC50 values of 0.07 µM forFormula:C24H32N4O2Purity:98%Color and Shape:SolidMolecular weight:408.54(R,R)-CXCR2-IN-2
CAS:'(R,R)-CXCR2-IN-2 is a brain-penetrating diastereoisomer and CXCR2 antagonist with pIC50 of 9 (Tango) and 6.8 (HWB Gro-α/CD11b).'Formula:C18H23ClN2O5SColor and Shape:SolidMolecular weight:414.93-Bromocytisine
CAS:3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Formula:C11H13BrN2OPurity:99.974%Color and Shape:SolidMolecular weight:269.14Ref: TM-T10108
1mg95.00€1mL*10mM (DMSO)178.00€5mg202.00€10mg293.00€25mg494.00€50mg710.00€100mg973.00€200mg1,305.00€HCV-IN-43
CAS:HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].Formula:C26H26FN3O5SColor and Shape:SolidMolecular weight:511.57Rohitukine
CAS:Rohitukine: anticancer, modulates apoptosis, antiadipogenic, antidyslipidemic, gastroprotective, antifertility, antileishmanial.Formula:C16H19NO5Color and Shape:SolidMolecular weight:305.33c-Myc inhibitor 8
CAS:c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.Formula:C19H12BrClF3NO3S2Color and Shape:SolidMolecular weight:538.795′-Guanylyl methylenediphosphonate sodium
CAS:5′-Guanylyl methylenediphosphonate (sodium) serves as a GTP analogue and acts as a specific, competitive inhibitor of the GTP reaction in protein synthesis [1].Formula:C11H15N5Na3O13P3Color and Shape:SolidMolecular weight:587.15PIM1-IN-4
CAS:PIM1-IN-4: strong PIM1 inhibitor, also blocks SGK-1, PKA, CaMK-1, GSK3β, MSK1; promising for cancer studies.Formula:C27H25BrCl2CuN6OPurity:98%Color and Shape:SolidMolecular weight:663.88Cisd2 agonist 1
CAS:Cisd2 agonist 1 is a CISD2) agonist (EC50: 34 nM) with potential anticancer activity and can be used to study non-alcoholic fatty liver disease (NAFLD).Formula:C14H13FN2O3SPurity:99.06%Color and Shape:SolidMolecular weight:308.33Ref: TM-T78093
1mg71.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg485.00€50mg802.00€100mg1,099.00€500mg2,205.00€PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFormula:C19H12F4O2SPurity:98%Color and Shape:SolidMolecular weight:380.36SC 53228
CAS:SC 53228 is a specific leukotriene B4 receptor antagonist.Formula:C31H41NO7Color and Shape:SolidMolecular weight:539.662′-Thioadenosine
CAS:2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM againstFormula:C10H13N5O3SPurity:98%Color and Shape:SolidMolecular weight:283.31JP104
CAS:JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].Formula:C25H30N2O3Purity:98%Color and Shape:SolidMolecular weight:406.52NAS-181 free base
CAS:NAS-181 free base is a 5-HT(1B) receptor antagonist.Formula:C19H26N2O4Color and Shape:SolidMolecular weight:346.42Inz-5
CAS:Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.Formula:C18H14F4N6Color and Shape:SolidMolecular weight:390.34DGKζ-IN-3
CAS:DGKζ-IN-3 is an inhibitor of diacylglycerol kinase zeta (DGK-ζ), employed in the treatment of both liquid and solid cancers, as well as other diseases regulatedFormula:C20H16ClF3N4O3SColor and Shape:SolidMolecular weight:484.88ROMK-IN-32
CAS:ROMK-IN-32 is an inhibitor of the extra-renal medullary potassium channel (ROMK) (IC50: 35 nM) and also inhibits hERG (IC50: 22 μM).Formula:C24H28N4O5Color and Shape:SolidMolecular weight:452.5Darglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Formula:C23H20N2O4SPurity:99.76%Color and Shape:SolidMolecular weight:420.48TRPC3/6-IN-2
CAS:TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].Formula:C18H23F2N5Color and Shape:SolidMolecular weight:347.41CGC 11093
CAS:CGC 11093: A polyamine analog inhibiting human prostate tumor growth in mice; may help regress choroidal neovascularization.Formula:C17H42Cl4N4Color and Shape:SolidMolecular weight:444.35MK-7246
CAS:MK-7246 is a potent and specific CRTH2 antagonist (Ki: 2.5 nM).Formula:C21H21FN2O4SColor and Shape:SolidMolecular weight:416.47AZD1092
CAS:AZD1092 is the glucokinase enzyme activator.Formula:C24H26N4O5Purity:98%Color and Shape:SolidMolecular weight:450.49Antifungal agent 66
CAS:Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects onFormula:C19H25ClO6Color and Shape:SolidMolecular weight:384.85
