Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,797 products)
- Apoptosis(6,259 products)
- Cell Cycle/Checkpoint(4,836 products)
- Chromatin/Epigenetics(2,592 products)
- Cytoskeletal Signaling(1,534 products)
- DNA Damage/DNA Repair(2,880 products)
- Endocrinology/Hormones(3,748 products)
- Enzyme(3,670 products)
- GPCR/G-Protein(8,985 products)
- Immunology and Inflammation(3,797 products)
- Influenza Virus(299 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,250 products)
- Membrane Transporter/Ion Channel(3,148 products)
- Metabolism(10,144 products)
- Microbiology/Virology(7,591 products)
- Neuroscience(10,345 products)
- Other Inhibitors(35,830 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,421 products)
- Proteases/Proteasome(1,681 products)
- Stem Cell and Derivatives(748 products)
- Tyrosine Kinase/Adaptors(1,961 products)
- Ubiquitination(1,721 products)
Show 16 more subcategories
Found 66564 products of "Inhibitors"
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VDR agonist 1
CAS:Compound 28 is a nonsteroidal VDR agonist with 690 nM potency, inducing cell cycle arrest and apoptosis in MCF-7 cells.Formula:C32H51N3O2Purity:98%Color and Shape:SolidMolecular weight:509.77DG013A
CAS:DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.Formula:C27H37N4O4PColor and Shape:SolidMolecular weight:512.58BTK-IN-7
BTK-IN-7 is a potent inhibitor for BTK with 4.0 nM IC50, highly selective over ITK and EGFR, showing strong antitumor activity.Formula:C30H32N6O4Color and Shape:SolidMolecular weight:540.61Sequoiaflavone
CAS:Sequoiaflavone is a biflavone isolated from Ginkgo biloba.Formula:C31H20O10Color and Shape:SolidMolecular weight:552.48STA-1474
CAS:STA-1474, a soluble prodrug of ganetespib (STA-9090), becomes a strong HSP90 inhibitor effective against canine tumors.Formula:C20H21N4O6PColor and Shape:SolidMolecular weight:444.38BMS-824
CAS:BMS-824: potent HCV NS5A inhibitor, IC50 ~5 nM, therapeutic index >10,000, specific to HCV.Formula:C27H25F3N4O5Color and Shape:SolidMolecular weight:542.51AZD-4121 tert-butylammonium
CAS:AZD-4121 tert-butylammonium is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.Formula:C40H50F2N4O7SColor and Shape:SolidMolecular weight:768.91LASSBio-1632
LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.Formula:C18H20N2O6SColor and Shape:SolidMolecular weight:392.43RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formula:C22H26BrN5O4SColor and Shape:SolidMolecular weight:536.44PRMT5-IN-1
CAS:PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50).Formula:C19H19ClN4O5Purity:98%Color and Shape:SolidMolecular weight:418.83DYRK1-IN-1
CAS:DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.Formula:C12H12N6Color and Shape:SolidMolecular weight:240.26Squalamine
CAS:Squalamine is an aminosterol compound, with potent broad spectrum antiviral activity.Formula:C34H65N3O5SPurity:98%Color and Shape:SolidMolecular weight:627.96Enprostil
CAS:Enprostil: synthetic PGE2 analog, reduces gastric acid, protects mucosa, lowers post-meal gastrin, treats ulcers effectively and safely.Formula:C23H28O6Purity:98%Color and Shape:SolidMolecular weight:400.46Oberadilol
CAS:Oberadilol is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory actionFormula:C25H30ClN5O3Color and Shape:SolidMolecular weight:483.99RO5101576
CAS:RO5101576 is a potent antagonist of LTB4 receptor.Formula:C36H38O8SPurity:98%Color and Shape:SolidMolecular weight:630.75L-97-1
CAS:L-97-1 is an antagonist of the adenosine A1 receptor.Formula:C29H38N6O3Purity:98%Color and Shape:SolidMolecular weight:518.65CXCR4 modulator-1
CAS:CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.Formula:C23H27N5O2Color and Shape:SolidMolecular weight:405.49PF-06273340
CAS:PF-06273340 是一种口服具有活力的、具有选择性的外周限制性Trk 泛抑制剂。Formula:C23H22ClN7O3Purity:98% - 98.00%Color and Shape:SolidMolecular weight:479.92PF1070A
CAS:PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothioneinFormula:C31H44N4O6Color and Shape:SolidMolecular weight:568.7D6808
D6808: selective c-Met inhibitor, IC50=2.9 nM, induces apoptosis and cell cycle arrest, for NSCLC/gastric cancer research.Formula:C30H25F3N6O2Color and Shape:SolidMolecular weight:558.55Glutaminyl Cyclase Inhibitor 3
CAS:Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formula:C24H32N6O2SPurity:98%Color and Shape:SolidMolecular weight:468.61HPK1-IN-16
CAS:HPK1-IN-16, a potent HPK1 inhibitor, useful for cancer research and treatment.Formula:C28H27FN4OColor and Shape:SolidMolecular weight:454.54ERK2 IN-1
CAS:ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.Formula:C36H34FN7O2SPurity:98%Color and Shape:SolidMolecular weight:647.76HDAC6-IN-9
CAS:HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.Formula:C19H16N2O3Purity:98.84%Color and Shape:SolidMolecular weight:320.34BSc5367
CAS:BSc5367 inhibits Nek1 kinase (IC50: 11.5 nM), key in cell cycle, DNA repair, impacting ALS, PKD, cancer.
Formula:C20H15N3O2Color and Shape:SoildMolecular weight:329.35FGFR1 inhibitor-6
FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.Formula:C27H19N5O4S2Color and Shape:SolidMolecular weight:541.6PF-07054894
CAS:PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.Formula:C24H30N6O4Color and Shape:SolidMolecular weight:466.53Butaprost
CAS:Butaprost: EP2 receptor agonist, EC50=33 nM, Ki=2.4 μM (murine), reduces fibrosis via TGF-β/Smad2.Formula:C24H40O5Purity:98%Color and Shape:SolidMolecular weight:408.57PI3K-IN-29
CAS:PI3K-IN-29: Strong PI3K block, inhibits Akt phosphorylation. IC50: U87MG 0.264µM, HeLa 2.04µM, HL60 1.14µM.Formula:C27H22ClN7O3SColor and Shape:SolidMolecular weight:560.03Isobetanin
CAS:Isobetanin is a betacyanin that has been shown to enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells.
Formula:C24H26N2O13Color and Shape:SolidMolecular weight:550.47NTPDase-IN-2
CAS:NTPDase-IN-2 inhibits h-NTPDase-2/-8 (IC50: 0.04, 2.27 µM), non-competitive for h-NTPDase-1/-2 (Km: 74 µM); useful in cancer, immune, bacterial research.Formula:C24H20FN3OS2Color and Shape:SolidMolecular weight:449.56Nipradolol
CAS:Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.Formula:C15H22N2O6Color and Shape:SolidMolecular weight:326.35Anticancer agent 27
Anticancer agent 27 is a promising candidate for the treatment of cancer and deserves further development.Formula:C28H31NO6Color and Shape:SolidMolecular weight:477.55Rimegepant sulfate hydrate
CAS:Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.Formula:C56H64F4N12O13SColor and Shape:SolidMolecular weight:1221.2526CCR7 Ligand 1
CAS:CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.Formula:C22H29N5O5SColor and Shape:SolidMolecular weight:475.56LSD1-IN-16
LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.Formula:C20H18N2OSColor and Shape:SolidMolecular weight:334.43SGK1-IN-3
CAS:SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.Formula:C23H20Cl2N6O3SColor and Shape:SolidMolecular weight:531.414CPX-351
CAS:CPX-351 (Vyxeos) is a liposomal encapsulant of cytarabine and Zoerythromycin with potential antitumor activity.Formula:C36H42N4O15Purity:98.95% - 99.763%Color and Shape:SolidMolecular weight:770.74SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Formula:C32H32N4O3Purity:98%Color and Shape:SolidMolecular weight:520.622R,4R-Sacubitril
CAS:2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.Formula:C24H29NO5Purity:98%Color and Shape:SolidMolecular weight:411.49NAZ2329
CAS:NAZ2329: Cell-permeable, targets R5 RPTPs, inhibits hPTPRZ1 (IC50=7.5 μM) & hPTPRG (IC50=4.8 μM), hampers glioblastoma growth, affects stem cell traits.Formula:C21H18F3NO4S3Color and Shape:SoildMolecular weight:501.56Cdc7-IN-10
CAS:Cdc7-IN-10 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in studies of proliferative diseases.Formula:C20H22F2N4O2SColor and Shape:SolidMolecular weight:420.48MAO-B-IN-6
MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.Color and Shape:SolidRosiptor acetate
CAS:Rosiptor (AQX-1125) activates SHIP1, inhibits Akt, and reduces inflammation and allergy in rodents.Formula:C22H39NO4Purity:98%Color and Shape:Solid PowderMolecular weight:381.55Topoisomerase IIα-IN-4
Topoisomerase IIα-IN-4 (F2) is a non-intercalative ATP-competitive inhibitor of human DNA topoisomerase II, specifically inhibiting TopoIIα with an IC50 valueFormula:C25H21NO2Color and Shape:SolidMolecular weight:367.44PGDM
CAS:PGD2 is involved in allergy, asthma, sleep, temperature regulation, inhibits clotting, and relaxes blood vessels; PGDM, its metabolite, is a biomarker.Formula:C16H24O7Color and Shape:SolidMolecular weight:328.36SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormula:C22H20ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:464.87AZD2353
CAS:AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).Formula:C22H19ClFN3O3Color and Shape:SolidMolecular weight:427.86GSK579289A
CAS:GSK579289A is an inhibitor of benzimidazole thiophene.Formula:C26H27ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:511.04VEGFR-2/DHFR-IN-2
VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.4
