
Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10345 products of "Benzimidazole and Imidazole Derivatives"
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N-(2-Phenethyl)benzamide
CAS:<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formula:C15H15NOPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:225.29 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS:<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formula:C17H17F2N3O4SPurity:Min. 95%Color and Shape:Off-white to yellow powder.Molecular weight:397.4 g/molDi-2-thienylmethanone
CAS:<p>Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.</p>Formula:C9H6OS2Purity:Min. 95%Color and Shape:White PowderMolecular weight:194.28 g/mol2-Hydroxy-2,2-bis(2-thienyl) acetic acid
CAS:<p>2-Hydroxy-2,2-bis(2-thienyl) acetic acid is a long-acting bronchodilator that can be administered by inhalation. It has been used in the clinical development of medicines for the treatment of asthma and chronic obstructive pulmonary disease. 2-Hydroxy-2,2-bis(2-thienyl) acetic acid is chemically related to pyridinium compounds. It is a potent inhibitor of muscarinic receptors and has an anticholinergic profile similar to atropine. The safety profile of this drug seems to be favourable in humans with no major side effects reported so far.</p>Formula:C10H8O3S2Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:240.3 g/molRabeprazole Impurity 2
CAS:<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>Formula:C18H19N3O4Purity:Min. 95%Molecular weight:341.36 g/mol3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one
CAS:<p>3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one is a triazine derivative that is used as an analytical reagent and intermediate. It has been used as a wastewater analysis method to measure the concentration of carbamazepine. 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one has also been shown to be useful in developing analytical methods for clinical trials. 3DCTKP has also been used to test the matrix effect of carbamazepine by analyzing it in different matrices such as water and human plasma.</p>Formula:C9H6Cl2N4OPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:257.08 g/mol5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity)
CAS:<p>5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity) is an analytical standard used as a reference in HPLC assays for donepezil. It is also a metabolite of donepezil and has been found to have pharmacological activity similar to that of the parent compound. This impurity is present in donepezil drug products at levels up to 0.5%.</p>Formula:C17H21NO3Purity:Min. 95%Molecular weight:287.35 g/molOmeprazole impurity F and G
CAS:<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formula:C16H13N3O2SPurity:Min. 95%Color and Shape:Red PowderMolecular weight:311.36 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/mol(R)-5-Hydroxymethyl tolterodine
CAS:<p>(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to</p>Formula:C22H31NO2Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:341.49 g/molN-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
CAS:<p>N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.</p>Formula:C16H9Cl4N5OPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:429.09 g/molN-Desmethyl galanthamine
CAS:Controlled Product<p>N-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.</p>Formula:C16H19NO3Purity:Min. 95%Molecular weight:273.33 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Formula:C17H19N3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:377.42 g/mol2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].</p>Formula:C15H15N3OS2Purity:Min. 95%Molecular weight:317.43 g/molVarenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26Methyl 6-bromo-1H-indazole-3-carboxylate
CAS:Formula:C9H7BrN2O2Purity:95%Color and Shape:SolidMolecular weight:255.0712,4-Dibromo-1H-imidazole
CAS:Formula:C3H2Br2N2Purity:95%Color and Shape:SolidMolecular weight:225.871Methyl 5-amino-1H-benzo[d]imidazole-2-carboxylate hydrochloride
CAS:Formula:C9H10ClN3O2Purity:95%Molecular weight:227.65(1-Methyl-1H-imidazol-2-yl)-oxo-acetic acid ethyl ester
CAS:Formula:C8H10N2O3Purity:98%Molecular weight:182.179Benzoimidazol-1-yl-acetic acid
CAS:Formula:C9H8N2O2Purity:95%Color and Shape:SolidMolecular weight:176.1754-Chloro-3-iodo-1H-indazole
CAS:Formula:C7H4ClIN2Purity:98%Color and Shape:SolidMolecular weight:278.482-Chloromethylbenzimidazole
CAS:Formula:C8H7ClN2Purity:95%Color and Shape:Tan powderMolecular weight:166.61Clotrimazole
CAS:Formula:C22H17ClN2Purity:95+%Color and Shape:Crystalline Powder,PowderMolecular weight:344.84(S)-tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS:Purity:98%Molecular weight:395.0950012(S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate
CAS:Formula:C15H18N2O5Purity:96%Molecular weight:306.3185-Methoxy-1H-benzo[d]imidazole-2-thiol
CAS:Formula:C8H8N2OSPurity:98%Color and Shape:SolidMolecular weight:180.232-((1-Benzyl-1H-indazol-3-yl)oxy)acetic acid
CAS:Formula:C16H14N2O3Purity:95%Color and Shape:SolidMolecular weight:282.299(S)-3-Boc-2,2-Dimethyl-oxazolidine-4-carboxylic acid methyl ester
CAS:Formula:C12H21NO5Purity:98%Color and Shape:LiquidMolecular weight:259.3025-Methyl-1H-indazole-3-carbaldehyde
CAS:Formula:C9H8N2OPurity:97%Color and Shape:Liquid, No data available.Molecular weight:160.1761-[(4S)-4-(1-Methylethyl)-2-thioxo-3-oxazolidinyl]-1-propanone
CAS:Purity:98%Color and Shape:SolidMolecular weight:201.27999886-Chloro-1H-indazol-4-amine
CAS:Formula:C7H6ClN3Purity:95.0%Color and Shape:SolidMolecular weight:167.025Di(1H-imidazol-2-yl)methanimine
CAS:Formula:C7H7N5Purity:95%Color and Shape:SolidMolecular weight:161.168Methyl 2-chlorooxazole-4-carboxylate
CAS:Formula:C5H4ClNO3Purity:98%Color and Shape:SolidMolecular weight:161.541-ethyl-2,3-dimethylimidazolium tetrafluoroborate
CAS:Formula:C7H13BF4N2Purity:97%Molecular weight:2123-(Aminomethyl)-1H-indazole
CAS:Formula:C8H9N3Purity:97%Color and Shape:SolidMolecular weight:147.1811-Ethyl-3-methylimidazolium Acetate
CAS:Formula:C8H14N2O2Purity:95%Color and Shape:Liquid, Clear or HazyMolecular weight:170.212(1-Methyl-1H-indazol-4-yl)boronic acid
CAS:Formula:C8H9BN2O2Purity:98%Color and Shape:SolidMolecular weight:175.987-Bromo-2-methyl-2H-indazole
CAS:Formula:C8H7BrN2Purity:98%Color and Shape:No data available.Molecular weight:211.0621-Methyl-2-(methylthio)-1H-imidazole
CAS:Formula:C5H8N2SPurity:97%Color and Shape:LiquidMolecular weight:128.197-(Diethylamino)-3-(1-methyl-1H-benzo[d]imidazol-2-yl)-2H-chromen-2-one
CAS:Formula:C21H21N3O2Purity:98%Molecular weight:347.4184-Bromo-5-methyl-1H-indazole
CAS:Formula:C8H7BrN2Purity:95%Color and Shape:SolidMolecular weight:211.0624-Methyl-1H-imidazole-2-carboxylic acid
CAS:Formula:C5H6N2O2Purity:97%Color and Shape:Solid, Light grey powderMolecular weight:126.1152-Mercaptobenzimidazole
CAS:Formula:C7H6N2SPurity:95%Color and Shape:Solid, CrystallineMolecular weight:150.2Methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate
CAS:Formula:C9H9N3O2Purity:98%Color and Shape:SolidMolecular weight:191.19tert-Butyl 6-hydroxy-1H-indazole-1-carboxylate
CAS:Formula:C12H14N2O3Purity:97%Color and Shape:Liquid, No data available.Molecular weight:234.2552-Amino-1H-benzo[d]imidazole-5-carboxylic acid
CAS:Formula:C8H7N3O2Purity:95%Color and Shape:SolidMolecular weight:177.1631-Butyl-3-methylimidazolium hydroxide, 20% in ethanol solution
CAS:Purity:70%Color and Shape:LiquidMolecular weight:156.2291,3-Dicyclohexyl-1H-imidazol-3-ium tetrafluoroborate
CAS:Formula:C15H25BF4N2Purity:98%Molecular weight:320.185-Bromo-1-methyl-1H-indazol-3-amine
CAS:Formula:C8H8BrN3Purity:98%Color and Shape:SolidMolecular weight:226.077(4-Imidazol-1-yl-phenyl)methanol
CAS:Formula:C10H10N2OPurity:98%Color and Shape:SolidMolecular weight:174.203(4R,5R)-tert-Butyl 4-cyano-2,2,5-trimethyloxazolidine-3-carboxylate
CAS:Purity:98%Molecular weight:240.30299386-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID
CAS:Purity:95%Color and Shape:SolidMolecular weight:241.0440063(R)-4-Methyloxazolidin-2-one
CAS:Formula:C4H7NO2Purity:95%Color and Shape:SolidMolecular weight:101.105(4S)-2,2-DIMETHYL-3-N-CBZ-4-(HYDROXYMETHYL)OXAZOLIDINE
CAS:Formula:C14H19NO4Purity:96%Molecular weight:265.309(S)-1-Boc-2,2-Dimethyl-4-hydroxymethyl-oxazolidine
CAS:Formula:C11H21NO4Purity:95%Color and Shape:SolidMolecular weight:231.2925-Bromo-1H-indazole-3-carboxylic acid
CAS:Formula:C8H5BrN2O2Purity:95%Color and Shape:SolidMolecular weight:241.044


