Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Found 79473 products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
CAS:Formula:C34H33N3O5Molecular weight:563.65Decylaminoquat Impurity of Colesevelam
CAS:Formula:C19H43N2BrHBrMolecular weight:299.57 : 79.90 : 80.91Nicotine Ditartrate Dihydrate
CAS:Formula:C10H14N2(C4H6O6)(H2O)Molecular weight:162.24 : 2(150.09) : 2(18.02)Lanicemine dihydrochloride
CAS:<p>Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is an NMDA channel blocker with antidepressant activity and can be used to study neurological diseases.</p>Formula:C13H16Cl2N2Purity:98.37%Color and Shape:SolidMolecular weight:271.19Ro 25-6981 Maleate
CAS:<p>Ro 25-6981 Maleate is an NMDA receptor antagonist used in the study of neurological disorders such as Parkinson's and epilepsy.</p>Formula:C26H33NO6Purity:99.42%Color and Shape:SolidMolecular weight:455.54(E)-4-((1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopent-3-en-2-yl)amino)-4-oxobutanoic acid
Formula:C24H27NO5Molecular weight:409.484,5,6,7-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridine
CAS:Controlled Product<p>Applications 4,5,6,7-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridine (cas# 109904-25-8) is a compound useful in organic synthesis.<br></p>Formula:C26H23NSColor and Shape:NeatMolecular weight:381.532-Bromoacetic Acid
CAS:<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>Formula:C2H3BrO2Color and Shape:Light YellowMolecular weight:138.953(4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one
CAS:Controlled Product<p>Applications AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996); Robertson, I. et al.: Biochem., 47, 7485 (2008);<br></p>Formula:C11H13N3OColor and Shape:Light Yellow To BrownMolecular weight:203.24Pyridin-3-yl Dimethylcarbamate
CAS:Controlled Product<p>Applications Pyridin-3-yl dimethylcarbamate (cas# 51581-32-9) is a useful research chemical.<br></p>Formula:C8H10N2O2Color and Shape:ColourlessMolecular weight:166.18Scopoline Methobromide
CAS:<p>Applications Scopoline Methobromide is an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.<br>References Moffett, R.B.. et al.: J. Am. Chem. Soc., 77, 1245 (1955); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006)<br></p>Formula:C9H16NO2·BrColor and Shape:White To Light GreyMolecular weight:250.133-Hydroxypyridine
CAS:Controlled ProductFormula:C5H5NOColor and Shape:White To Light BeigeMolecular weight:95.102-(2-Aminoethylamino)ethanol
CAS:Controlled Product<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>Formula:C4H12N2OColor and Shape:NeatMolecular weight:104.1509Methyl Acetoacetate
CAS:Controlled Product<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>Formula:C5H8O3Color and Shape:NeatMolecular weight:116.122-Oxo Clopidogrel Hydrochloride(Mixture of Diastereomers)
CAS:Controlled Product<p>Applications The essential intermediate metabolite from which the active metabolite of Clopidogel is formed.<br>References Feliste, R., et al.: Thromb. Res., 48, 403 (1987), Savi, P., et al.: Biochem. Pharmacol., 44, 527 (1992), Herbert, J., et al.: Cardiovasc Drug. Rev., 11, 180 (1993), Sugidachi, A., et al.: B. J. Pharmacol., 132, 47 (2001)<br></p>Formula:C16H17Cl2NO3SColor and Shape:NeatMolecular weight:374.28Tacrolimus (FK506)
CAS:<p>Applications An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999)<br></p>Formula:C44H69NO12Color and Shape:NeatMolecular weight:804.02FK-506-13C,D2 (Major) (Tacrolimus) (>85%)
CAS:Controlled ProductFormula:CC43D2H67NO12Purity:>85%Color and Shape:NeatMolecular weight:807.02Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Li, X., et. al.: Lett. Org. Chem., 12, 217 (2015); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C13H13NO3SColor and Shape:NeatMolecular weight:263.31N1-Acetyl Triethylenetetramine Trihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications N1-Acetyl Triethylenetetramine is a monoacetylated metabolite of the selective CuII-chelator Triethylenetetramine (T776630).<br>References Murata, Y. et al.: Biomed. Res. Trace Elem., 4, 185 (1993): Lu, J. et al.: J. Clin. Pharmacol., 50, 647 (2010); Lu, J. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 859, 62 (2007);<br></p>Formula:C8H23Cl3N4OColor and Shape:NeatMolecular weight:297.651-(3-Hydroxypropyl)theobromine
CAS:Controlled ProductFormula:C10H14N4O3Color and Shape:White To Off-WhiteMolecular weight:238.243Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C31H38ClN7O7S2•xH2OColor and Shape:White To Off-WhiteMolecular weight:720.26(15R)-Bimatoprost Acid
CAS:Controlled Product<p>Applications (15R)-Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820). (15R)-Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor.<br>References Balapure, A.K. et al.: Biochem. Pharmacol., 38, 2375 (1989); Hellberg, M.R. et al.: J. Ocular Pharmacol. Ther., 19, 97 (2003); Krishna, P.M. et al.: J. Pharm. res., 4, 2381 (2011); Resul, B., et al.: J. Med. Chem., 36, 243 (1993)<br></p>Formula:C23H32O5Color and Shape:NeatMolecular weight:388.497Febuxostat-d9
CAS:Controlled Product<p>Applications Labelled Febuxostat (F229000). Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formula:C16D9H7N2O3SColor and Shape:NeatMolecular weight:325.43Ethyl 2-Chloracetoacetate
CAS:<p>Applications Ethyl 2-Chloracetoacetate is used in the preparation of oxazoles and thiazoles as agonists for peroxisome proliferator-activated receptor δ. It is also used to synthesize dimethylimidazothiadiazolecarbohydrazides with anticancer activities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sznaidman, M., et al.: Bioorg. Med. chem. Lett., 13, 1517 (2003); Terzioglu, N., et al.: Eur. J. Med. Chem., 38, 781 (2003)<br></p>Formula:C6H9ClO3Color and Shape:NeatMolecular weight:164.59N-Demethylivabradine
CAS:Controlled ProductFormula:C26H34N2O5Color and Shape:Light Brown To BrownMolecular weight:454.56
![(E)-4-((1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopent-3-en-2-yl)amino)-4-oxobutanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FST-EA%2Fthumb-webp%2FEA-CP-S18147.webp&w=3840&q=75)
![4,5,6,7-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FT295795.webp&w=3840&q=75)
