Amino Acids (AA)

<p>N2,N6-Bis-cbz-L-lysine is a synthetic acid transporter that is used to inhibit the transport of lysine across the cell membrane. It is an amide, which can be synthesized from lysine and benzoyl chloride. This compound has been shown to have an inhibitory effect on tumor growth in vitro and in vivo. N2,N6-Bis-cbz-L-lysine is active when targeting acidic environments such as tumors. The carbonyl group of this molecule reacts with the hydroxyl group at C4′ on the ribose ring of nucleosides to form a 1,2 diol moiety. This reaction leads to inhibition of DNA synthesis by preventing RNA polymerase from binding to DNA.</p>

<p>H-Pro-Pro-Pro-Pro-OH is a proteolytic enzyme that has been shown to have potential applications in drug design. The enzyme is able to cleave proteins, such as albumin, at different sites. It can be used to optimize the design of therapeutic drugs by highlighting the parameters that are important for successful protein cleavage. The enzyme has also been shown to have toxicological properties and interacts with serum albumin. H-Pro-Pro-Pro-Pro-OH is a protease that can be found in human serum.</p>

<p>Please enquire for more information about Fmoc-Tyr(Et)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Apelin-12 is a peptide hormone that belongs to the group of apelin family. It is an endogenous agonist for the apelin receptor and has been shown to affect metabolic and cardiovascular regulation. Apelin-12 has been found to increase systolic blood pressure, which may be due to its ability to inhibit the synthesis of nitric oxide in the heart. It also exhibits anti-inflammatory properties, which have been shown in vivo using a model of colitis induced by dextran sulfate sodium (DSS). The biological properties of this hormone are not yet fully understood. However, it is known that it has effects on cardiac contractility and myocardial infarct size in vivo. Further investigation into this protein's role in inflammatory diseases and metabolic disorders may lead to new treatments for these conditions.</p>

<p>Ac-Ser-Asp-Lys-Pro-OH is a tetrapeptide that has been shown to stimulate the growth of cells in vitro. It has been found to inhibit the production of interleukin-1β and tumor necrosis factor α, which are cytokines that are involved in inflammation. Ac-Ser-Asp-Lys-Pro-OH stimulates the production of growth factor β1 and collagen, which may be due to its ability to bind to toll like receptor 4 (TLR4). Acetylserotonin has been shown to have antiinflammatory and antifibrotic properties in animal models. Acetylserotonin also inhibits cancer cell growth and reduces drug resistance.</p>

<p>Please enquire for more information about Z-Thr(Bzl)-OH·DCHA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Leu-Asp-Gln-Trp-Phe-Gly-NH2 is a peptide that was found to inhibit the activity of vasoactive intestinal peptide (VIP). It binds to VIP with high affinity and competitively inhibits its binding to VIP receptors. Ac-Leu-Asp-Gln-Trp-Phe-Gly-NH2 has an inhibitory effect on the maximal response of VIP in tissues, such as the intestine. This peptide also has an irritant effect on the intestine, which may be due to its competitive inhibition of VIP receptor sites. Ac-Leu-Asp-Gln-Trp-Phe Gly NH2 has been shown to have a concentration response curve for inhibiting the activity of Vip.</p>

<p>Antifreeze Polypeptide 6 (AFP6) is a protein that belongs to the family of antifreeze proteins. AFP6 binds to ion channels and prevents the flow of ions, which prevents the formation of ice crystals. It also has been shown to interact with other proteins, such as receptors and peptides. This protein has been shown to be a research tool for studying cell biology and pharmacology. The CAS number for AFP6 is 122604-16-4.</p>

<p>Please enquire for more information about (Des-Gly10,D-His2,D-Ser4,D-Leu6,Pro-NHEt 9)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Prepro VIP (81-122) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polyphemusin II-derived peptide H-Arg-Arg-2-Nal-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit (PIIH) is a cyclic polypeptide with a disulfide bond. PIIH binds to the alpha4beta1 integrin receptor, which is involved in the adhesion of leukocytes to endothelial cells and the migration of monocytes and lymphocytes. PIIH has been shown to be a potent inhibitor of chemokine binding to cxcr4, an important regulator of inflammatory response in mouse tumor models. PIIH also inhibits hiv infection as it inhibits the release of virus from infected cells. This pharmacological effect is mediated by its ability to bind HIV gp120 and block gp120 binding to CD4 receptors on target cells.</p>

<p>Please enquire for more information about H-D-Cys(4-methoxytrityl)-2-chlorotrityl resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-b-Ala-Ala-Pro-OH is a reaction component that can be used in the synthesis of peptides and other compounds. It is a building block for the preparation of complex compounds, such as small molecules, polymers and natural products. Fmoc-b-Ala-Ala-Pro-OH has been shown to be useful in the synthesis of various types of reagents, including antibiotics and pharmaceuticals. This chemical has been reported as a useful scaffold for the preparation of high quality research chemicals. Fmoc-b-Ala-Ala-Pro is also an intermediate in the synthesis of speciality chemicals and fine chemicals.</p>

<p>Please enquire for more information about Fmoc-Mating Factor a TFA salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ([13C6]Leu6)-Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Neuropeptide Y (porcine) trifluoroacetate salt H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu -Ala -Arg Tyr Tyr Ser Ala Leu Arg His Tyr Ile Asn Leu Ile Thr Arg Gln Arg Tyr NH2 trifluoroacetate salt is a peroxidase enzyme that is biotinylated and purified from porcine sources. It has been used as an antiserum in the development of a plate sealer.</p>

<p>H-Pro-Glu-OH is a homologous peptide that belongs to the group of proteins. It is synthesized in the cells by polymerase chain reaction and can be used for diagnosis of infectious diseases. It has been shown to induce antibody response in mice. H-Pro-Glu-OH is also active against Mycobacterium tuberculosis, which may be due to its ability to bind to the tyrosine kinase domain on protein genes. This peptide has been shown to have anti-inflammatory properties, inhibiting fatty acid production and leading to necrotic cell death.</p>

<p>1-Boc-1-methylhydrazine is a molecule that is used as a chemical intermediate for pharmaceuticals. It has been shown to inhibit the proteasome pathway by targeting the ubiquitin-proteasome system, which is involved in protein degradation and cell growth regulation. 1-Boc-1-methylhydrazine has synergistic effects when combined with other inhibitors of the ubiquitin proteasome system, such as anamorelin. It was found to be effective at inhibiting the growth of k562 cells but not normal cells, suggesting that it may have therapeutic applications for inflammatory bowel disease.</p>

<p>Suc-Ala-Leu-Pro-Phe-AMC tfluoroacetic acid is a synthetic peptide that has been shown to have the ability to inhibit the function of an enzyme called isomerase. It binds to the catalytic region of the enzyme and blocks its activity, which prevents the production of amino acid molecules. Suc-Ala-Leu-Pro-Phe-AMC tfluoroacetic acid also has immunosuppressive properties, which are due to its ability to bind to regulatory domains in cells and prevent their transcriptional activation. This molecule also has a catalytic function and can be used as a building block for synthesizing other molecules with similar functions.</p>

<p>Please enquire for more information about Big Endothelin-3 (22-41) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-Glu(OBzl)-Ala-Arg-AMC·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>ACTH is a hormone that belongs to the class of endogenous peptides. It is synthesized and secreted by the anterior pituitary gland in response to adrenocorticotropic hormone (ACTH) from the hypothalamus. ACTH has a high affinity for cells with receptors for ACTH and has been shown to stimulate cyclase activity, leading to increased production of cAMP. ACTH also binds to membranes and micelles, which are lipid bilayers with hydrophobic regions. The binding of ACTH at these sites alters the physical properties of these structures by increasing their permeability or solubility. This leads to changes in their functions, including modulation of membrane-bound enzymes such as adenylate cyclase activity.</p>

<p>Dansyl-Tyr-Val-Gly-OH trifluoroacetate salt is a glyoxylate analog that can be used as a substrate in the kinetic assays for glyoxalase I. The enzyme catalyses the conversion of this compound to Dansylglyoxal, which can be detected by absorbance at 360 nm. The second order rate constant and acidic pH of the reaction have been determined using biophysical experiments and expressed as a function of substrate concentration. Inactivates papilloma virus, which is the virus that causes genital warts, at low concentrations.</p>

<p>Please enquire for more information about ACTH (1-14) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt is a synthetic, hydroxamic acid that inhibits the activity of collagenase, gelatinase and stromelysin. It also has inhibitory activities against metalloproteinases, such as matrix metalloproteinases and serine proteinases. 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt has been shown to inhibit the production of proinflammatory cytokines in human skin fibroblasts. This agent also induces the production of granulocytes in vitro.</p>

<p>Please enquire for more information about H-Thr-Gly-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Tyr-Tyr-Tyr-OMe is a chiral, fluorinated, enantiomeric molecule that is synthesized by the reaction of an aryloxybenzene with tetrahydropyran and chlorine. This product has been used in asymmetric synthesis as a building block for pyrazole derivatives. It has also been used to produce alcohols and dialkylamino compounds.</p>

<p>Glutathione-monoethyl ester (reduced) H-Glu(Cys-Gly-OEt)-OH is a polymerase chain reaction (PCR) enhancer that consists of a glutathione monoester and an ethyl ester. Glutathione monoethyl ester (reduced) H-Glu(Cys-Gly-OEt)-OH is used as a cancer therapeutics agent in the treatment of cells with high levels of reactive oxygen species. It also inhibits drug efflux from cells and induces apoptosis in endothelial cells, which can lead to the inhibition of tumor growth. Glutathione monoethyl ester (reduced) H-Glu(Cys-Gly-OEt)-OH has been shown to cause changes in intracytoplasmic sperm and protein thiols in PC12 cells, which may be related to its ability to inhibit cell proliferation.</p>

<p>Please enquire for more information about (Leu116)-Prepro-Neuromedin U (104-136) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Mca-Pro-Lys-Pro-Leu-Ala-Leu-Dap (Dnp)-Ala-Arg-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PHM-27 is a human protein that contains a c-terminal histidine and n-terminal lysine. It contains an amino acid composition of histidine, valine, alanine, aspartic acid, glycine, serine, threonine, arginine, and methionine. PHM-27 is present in the cardiovascular system, nervous system, gastrointestinal system, and respiratory system. It has been shown to be involved in the synthesis of peptides important for blood clotting.</p>

<p>Please enquire for more information about H-Lys-Lys-Lys-Trp-Lys-Lys-Lys-OH acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Gly-p-iodo-Phe-Trp-OH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Amino-2-methoxy-dibenzofuran (3AMD) is a cytotoxic agent that is used in the treatment of bladder carcinoma. 3AMD inhibits DNA synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. 3AMD has been shown to be a potent inhibitor of cyclen-dependent kinases and to induce DNA damage in human cells. 3AMD also has significant cytotoxicity against malignant cells and has been shown to inhibit the growth of tumours in mice. 3AMD may have carcinogenic potential due to its structural similarity with other carcinogens such as aniline and aminobiphenyl.</p>

<p>Please enquire for more information about Boc-Gly-Phe-OBzl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Arg-Arg-4MbetaNA·3 HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Osteostatin is a recombinant human protein that inhibits bone growth by binding to and neutralizing the effect of forskolin. Osteostatin also has an inhibitory effect on cancer cells, as it inhibits mitochondrial pathways and prevents the activation of factor receptors. Osteostatin blocks the synthesis of cAMP, which is necessary for cell proliferation in cancer cells. The inhibition of cAMP levels leads to a decrease in the production of proteins that stimulate bone growth, such as runx2.</p>

<p>Please enquire for more information about Biotinyl-epsilon-aminocaproyl-D-Phe-Pro-Arg-chloromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Leptin (138-167) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Methoxyphenylboronic acid is a photophysical molecule that can be used as an analytical reagent in plant physiology and analytical chemistry. 3-Methoxyphenylboronic acid reacts reversibly with copper ions to form a complex. The binding constants of the copper complex depend on the pH of the solution, which can be altered by adding a phosphate derivative to the solution. This reaction was investigated using cross-coupling techniques and showed that the binding constants for this complex are dependent on the type of solvent used. 3-Methoxyphenylboronic acid has also been used to measure glucose levels in blood samples.</p>

<p>Please enquire for more information about H-D-Leu-bNA·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Mbs-D-Arg-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>3-Hydroxy-5-methylisoxazole (3HM) is a bacterial strain that belongs to the class of slow-release antibiotics. It is designed to release its active form, 3-hydroxy-5-methylisoxazole carboxylic acid, over time. The release process can be controlled by the ratio of 3HM and citric acid in the solution and by temperature changes. Titration calorimetry has shown that 3HM releases heat when it interacts with hydrochloric acid in a reaction solution. The detection sensitivity for this compound is 0.1 μM, which is lower than that for most other compounds of this type. Optimum concentrations are between 10 μM and 20 μM with a kinetic data of 0.0004/s at 20 μM concentration and an analytical method using vitro assays.</p>

<p>Gastrin I (human) Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp, is a peptide that belongs to the family of cholecystokinin. It is synthesized by solid phase synthesis on a carboxyl group with an efficiency of more than 95%. Gastrin I (human) Pyr-Gly-Pro-Trp... has been shown to be selective towards amide bond cleavage and has high yield. It is also stable in acidic conditions and can be detritylated with phenoxy.</p>

<p>Please enquire for more information about HIV Protease Substrate III-B (Native Sequence) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Angiotensin I/II 1-6 is a peptide containing amino acids 1-6; derived from from Angiotensin I/II.</p>

<p>Please enquire for more information about H-Ser-AMC hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glycylglycine is a hydrophobic amino acid that is found in collagen and other proteins. It has been shown to inhibit the activity of proteinases such as chymotrypsin, trypsin, and elastase, which are enzymes that break down proteins. Glycylglycine is a fluorescent molecule that can be detected by fluorescence microscopy and has been used in the study of protein-protein interactions. Glycylglycine is an acidic amino acid with an amino acid composition that consists of about 20% glycine, 40% hydroxyphenylalanine, 30% serine and 10% threonine. The spatial specificity of this compound has been studied using sephacryl electrophoresis, which showed it was localized to the extracellular matrix and in cell culture supernatants. Aminocoumarins are glycylglycines with an attached aminocoumarin group. Hydrolysis of gly</p>

<p>Please enquire for more information about (Deamino-Cys1,D-Orn 8)-Vasopressin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (His(1-Me)2)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ac-Met-Asp-Lys-Val-Leu-Asn-Arg-Glu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Osteocalcin (7-19) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Methylpentyl chloroformate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Phenylalanine benzyl ester hydrochloride is an ester of L-phenylalanine and benzoic acid. It has a solubility of 1.9g/L in water, 2.1g/L in methanol, and 0.8g/L in acetonitrile at 20°C. The melting point is 119°C to 120°C and the boiling point is 243°C to 244°C at atmospheric pressure. This compound can be synthesized by reacting formamide with L-phenylalanine chloride in the presence of hexamethylphosphoramide as a catalyst.</p>

<p>Pz-Pro-Leu-Gly-Pro-D-Arg-OH trifluoroacetate salt is a synthetic substrate that can be used for the synthesis of cyclic peptides. It has been shown to act as a competitive inhibitor of the serine protease, chymotrypsin, and cytochalasin B. Pz-Pro-Leu-Gly-Pro-D-Arg is a soluble substrate that can be used in tissue culture experiments with caco2 cells. This compound also has high solubility and is stable at pH values between 5 and 12. The optimum pH for this compound is 8.</p>

<p>Please enquire for more information about Boc-4-Abz-OSu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (3,5-Diiodo-Tyr1,D-Ala2,N-Me-Phe4,glycinol5)-Enkephalin acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Leu-Gly-Tyr-OH is a tripeptide that plays a role in cell proliferation, endothelial cell function and endothelial cell proliferation. H-Leu-Gly-Tyr-OH has been shown to be an inhibitor of the production of prostaglandin, which is involved in atherogenesis. H-Leu-Gly-Tyr-OH also inhibits the functions of cells by linking with amide bonds and hydrolysates.</p>

<p>Please enquire for more information about N-2-Cyanoethyl-Val-Leu-anilide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Boc-15-amino-4,7,10,13-tetraoxapentadecanoic acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Boc-15-amino-4,7,10,13-tetraoxapentadecanoic acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Please enquire for more information about H-D-Tyr(tBu)-allyl ester·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>BQ-123 is a cyclic peptide that has been shown to have a binding affinity for the serotonin receptor. The binding of BQ-123 to the receptor leads to a reduction in intracellular calcium concentration, which may be due to the inhibition of serine protease activity. This agent also inhibits the production of tumour necrosis factor-α (TNF-α) and has an inhibitory effect on cardiac contractility.</p>

<p>Spantide I is a peptide that is a member of the Galanin family. It has been shown to have a proliferative effect on retinal cells in vitro, and may be effective in treating diabetic retinopathy. Spantide I also inhibits the production of pancreatic enzymes and choroidal neovascularization. It is a diagnostic marker for cancer and other diseases, as well as being used in the treatment of hepatitis. The sequences for Spantide I are GG-S-P-A-N-T-I-D-E--I--H--Gly--Trp--Thr--Leu--Asn--Ser--Ala--Gly--Tyr--Leu--Leu---Gly---Pro---D----Arg---Pro-----Lys---Pro-------Gln-------D------Trp------Phe------D------Trp------Leu-------Leu-----NH2</p>

<p>The Fmoc-His(Boc)-OPfp is a synthetic peptide that has been shown to bind to angiotensin. It is chemically reactive and can be used in diagnostic assays for the detection of angiotensin. The Fmoc-His(Boc)-OPfp can also be used as a feedback control for sequence analysis, where it monitors the reaction sequence by binding to the last amino acid in the peptide. This binding prevents the formation of an enzyme with the enzyme reaction necessary for cell wall biosynthesis, inhibiting protein synthesis and cell division.</p>

<p>Neuropeptide AF is a peptide that is synthesized in the brain and has been shown to have a wide range of biological activities. It has been shown to block growth factor-β1, activate the ryanodine receptor, and cause neuronal death. Neuropeptide AF also activates the polymerase chain reaction (PCR) and can be used as a potential biomarker for Alzheimer's disease. Neuropeptide AF has been shown to decrease body mass index and improve long-term efficacy in patients with chronic heart disease. There is also evidence that Neuropeptide AF binds calcium ions, which may play a role in structural heart disease or cardiac function.</p>

<p>Please enquire for more information about Boc-D-Cys(NPys)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-Val-Leu-Arg-4MbNA·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Gly-Arg-Gly-Asp-Ser-Cys-OH trifluoroacetate salt is a photoelectron that binds to the integrin receptor. It has been shown that H-Gly-Arg-Gly-Asp-Ser-Cys-OH trifluoroacetate salt can inhibit protein synthesis in mesenchymal stromal cells. H Gly Arg Gly Asp Ser Cys OH trifluoroacetate salt can also be used as a reagent to determine the presence of amide bonds and to identify proteins. This compound may have biotechnological applications due to its biochemical properties.</p>

<p>Kemptide is a substrate molecule that has been shown to inhibit the enzyme activity of some protein kinases. Kemptide is a 3-amino acid peptide that contains the amino acids L-leucine, L-arginine, and L-arginine. It was originally isolated from an extract of human brain tissue and has been shown to inhibit the activity of protein kinase C (PKC), phosphorylase kinase, and glycogen synthase kinase 3β in vitro assays. Kemptide also inhibits the expression of genes encoding PKCα1, PKCα2, PKCδ, PKCε, PKCγ1, PKCγ2, PKCζ in t84 cells. The inhibition of these genes suggests that kemptide may be useful as a drug candidate for inhibiting protein kinases in vivo.</p>

<p>(R)-2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-enone is an organic compound that has been shown to induce apoptosis in prostate cancer cells. The mechanism of this induction is not yet fully understood, but it may be due to the inhibition of the synthesis of proteins required for cell division. It also had a significant effect on locomotor activity in mice. This compound has been shown to have acute toxicities, and its phase transition temperature is below room temperature. It can be used as a fumigant and an inorganic acid, and it has been proposed as a potential fluorescence probe for natural compounds.</p>

<p>Fibrinopeptide B (FPB) is a protein fragment of the blood clotting process. It is a member of the group of fibrinopeptides, which are formed by proteolytic cleavage of the precursor prothrombin. FPB is a low molecular weight peptide with an amino acid sequence that contains tryptophan and arginine residues, which are susceptible to oxidation by radiation. The presence of FPB in plasma can be used as an indicator for exposure to ionizing radiation. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry has been used to identify and quantify FPB in human plasma samples. This technique has also been applied to monitor the proteomic profile of activated platelets with high sensitivity using matrix molecules such as glycerol, ethylene glycol, and formamide as matrices for MALDI analysis.</p>

<p>Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzylpyrrolidinium is a natural compound that has been isolated from the Indian Ocean sea hare Dolabella auricularia. It has shown significant cytotoxicity against cancer cells as well as significant immunosuppressive activities in animals. Dolastatin 15 is an analog of dolastatin 10 and has been shown to be active against hepatitis B and C virus. It also has antiinflammatory properties and may be effective in combating autoimmune diseases. The synthesis of this compound is an asymmetric synthesis with a hydroxyl group on one side of the molecule and an amide on the other side.</p>

<p>Z-NHNH2·HCl is an amide containing a tetrapeptide. It has been used as a diagnostic agent for the detection of caerulein, a peptide that is produced by the pancreas in response to the presence of cholecystokinin (CCK). The monomers were prepared by reacting azide with benzyl chloroacetanilides and then cyclizing the product with triethylene glycol. The soybean extract was hydrolyzed with HCl to produce Z-NHNH2·HCl.</p>

<p>Please enquire for more information about (Tyr0)-Fibrinopeptide A (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Lys-(Des-Arg9)-Bradykinin trifluoroacetate salt H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH trifluoroacetate salt (KBP) is a peptide that increases blood pressure by binding to the b2 receptor. This drug has been shown to be a potent pressor in animals and humans, with a concentration response curve similar to that of epinephrine. KBP binds to the extracellular domain of the b2 receptor, which activates this receptor and promotes the release of growth factors, such as epidermal growth factor (EGF). The high affinity of KBP for the b2 receptor is thought to be due to its ability to sequester EGF.</p>

<p>Please enquire for more information about H-Ala-Ala-Ala-Tyr-Ala-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-O-tert-butyl-L-trans-4-hydroxyproline is a synthetic, cleavable peptide that can be used as a biomaterial. It is synthesized by coupling Fmoc-O-(tert-butoxycarbonyl)-L-trans(4R)-hydroxyproline with the amino acid N,N'-diisopropylcarbodiimide and 4-(dimethylamino)pyridine in a microwave reactor. The peptide has been shown to inhibit the enzyme matrix metalloproteinase 9 (MMP9), which plays an important role in tumor cell invasion and metastasis. This compound also has the ability to form conjugates with other molecules, such as lipopeptides, which may improve its therapeutic potential.</p>

<p>Suc-Ala-Gly-Pro-Phe-pNA is an amide that has been synthesized for the stabilization of proteins, peptides and nucleic acids. It has shown to be effective in preventing isomerization of casein and phosphatase (casein kinase II) by stabilizing the alpha helix structure. Suc-Ala-Gly-Pro-Phe-pNA also prevents fk506 binding to endoplasmic reticulum protein tyrosine kinases and isomerizes tyrosine to phenylalanine. The tetrapeptide sequence has been shown to be similar to sequences found in cellular proteins. This compound is a synthetic analog of the natural amino acid proline and can be used as a substitute in peptides or nucleotide sequences, due to its ability to stabilize these molecules against proteolysis or hydrolysis.</p>

<p>Please enquire for more information about (Gly21)-Amyloid b-Protein (1-40) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-Pro-DHPP resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Suc-Ala-His-Pro-Phe-pNA is an amide that binds to the casein kinase II, phosphatase, and inhibits cellular growth. The biochemical and cell specific activity of this drug target has been shown using biochemical and cellular assays. Suc-Ala-His-Pro-Phe-pNA has potent inhibitory activity against the enzyme phosphatase, which is a drug target for many diseases such as cancer. This compound also inhibits fk506 binding to endoplasmic reticulum protein FKBP12, which is a drug target for immunosuppressive therapy in organ transplantation. Suc-Ala-His-Pro-Phe-pNA has been shown to have high protease activity towards peptidyl substrates.</p>

<p>Please enquire for more information about Boc-Gly-PAM resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Met-Phe-Gly-OH is a hydrophobic amino acid. It has been shown to be present in human proteins, and it has been used as a marker for determining the sequence of amino acids in peptides. H-Met-Phe-Gly-OH is an acidic tripeptide that can be analysed using reversed phase high performance liquid chromatography (RPHPLC). This tripeptide is found in the peptide transporter, which transports amino acids across cellular membranes. The structural studies of H-Met-Phe-Gly-OH have revealed that this tripeptide has an alpha helix conformation, with two hydrogen bonds from the backbone amides to the backbone carbonyl groups.</p>

<p>Please enquire for more information about Ac-Phg-OMe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bis(4-methylphenyl) sulfone is an industrial chemical used in the manufacture of other chemicals. It is a sulfone that contains a hydroxyl group and a methylating agent. The reaction solution must be anhydrous and contain sodium carbonate, chloride, and methylating agent. The product can be synthesized by the Suzuki coupling reaction between an alkyl halide and an aryl boronic acid. This process requires activation energies of about 40-45 kcal/mol to drive the reaction forward. The hydrochloric acid reacts with the hydroxyl group on the sulfone to form a chlorosulfonic acid intermediate, which reacts with methylene chloride to produce bis(4-methylphenyl) sulfone. The carbonyl group on this intermediate is activated by adding methoxy groups, which are then replaced by chlorine atoms in order to form bis(4-chlorophenyl) sulfone.</p>

<p>Please enquire for more information about (D-Pro2,D-Trp6·8, Nle 10)-Neurokinin B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Methoxy-4-(trifluoromethyl)coumarin is a potent and selective aromatase inhibitor. It inhibits the activity of the enzyme, which converts testosterone to estradiol. The inhibition of this enzyme may be beneficial in the treatment of breast cancer. This compound has also been shown to inhibit the activity of P450 enzymes and coumarin derivatives, which are involved in drug metabolism and detoxification.</p>

<p>H-Met-Lys-OH formiate salt is an industrial chemical that can be used in the preparation of pharmaceutical preparations. It has been shown to have a potential to lower blood pressure and reduce the risk of cardiovascular diseases. H-Met-Lys-OH formiate salt is a lysine derivative that contains two amino acid residues, namely lysine and methionine. H-Met-Lys-OH formiate salt can be used as a therapeutic agent for prostate cancer by targeting tp53 mutations and radical prostatectomy. It can also be used as an antibacterial agent against gram-negative bacteria, such as Escherichia coli (E. coli).</p>

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<p>Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.</p>

<p>H-Asp-Asn-Gln-OH is a basic amino acid that is cleaved by endopeptidase to form H-Asp, H-Asn, and H-Gln. It is also cleaved by serine proteases to form the amino acid residues of arginyl, aspartyl, and glutamyl. The residue sequence can be determined through hplc analyses of microsomal proteins. This amino acid has been shown to have a regulatory effect on the metabolism of other amino acids in rat liver cells. Asparaginyl and glutamyl are essential for the synthesis of proproteins.</p>