Metabolismo
Gli inibitori del metabolismo sono composti che interferiscono con le vie metaboliche, alterando la produzione e l'utilizzo dell'energia all'interno delle cellule. Questi inibitori sono utilizzati per studiare la regolazione del metabolismo, il ruolo delle vie metaboliche in malattie come il cancro e il diabete e per sviluppare nuove strategie terapeutiche. Gli inibitori del metabolismo possono bersagliare vari enzimi e processi coinvolti nella glicolisi, nell'ossidazione degli acidi grassi e in altre funzioni metaboliche. Presso CymitQuimica, offriamo una vasta gamma di inibitori del metabolismo di alta qualità per supportare la tua ricerca in biochimica, disturbi metabolici e sviluppo di farmaci.
Sottocategorie di "Metabolismo"
- AhR(42 prodotti)
- Aminopeptidasi(76 prodotti)
- CETP(20 prodotti)
- Anidrasi carbonica(195 prodotti)
- Caseina chinasi(137 prodotti)
- DHFR(34 prodotti)
- Decarbossilasi(4 prodotti)
- Deidrogenasi(302 prodotti)
- FAAH(66 prodotti)
- FXR(62 prodotti)
- Fattore Xa(87 prodotti)
- Sintasi degli acidi grassi(37 prodotti)
- Ferroptosi(226 prodotti)
- GR(3 prodotti)
- GSNOR(4 prodotti)
- Glucokinasi(57 prodotti)
- Prolil-idrossilasi HIF/HIF(146 prodotti)
- Reduttasi HMG-CoA(33 prodotti)
- Idrossilasi(35 prodotti)
- IDO(84 prodotti)
- LDL(8 prodotti)
- Lipasi(107 prodotti)
- Lipidi(61 prodotti)
- Lipossigenasi(134 prodotti)
- MAO(87 prodotti)
- MPO(2 prodotti)
- NAMPT(40 prodotti)
- P450(6 prodotti)
- PAI-1(26 prodotti)
- PDE(167 prodotti)
- PED(1 prodotti)
- PKM(17 prodotti)
- PPAR(169 prodotti)
- Fosfolipasi(83 prodotti)
- ROR(47 prodotti)
- Recettore dei retinoidi(28 prodotti)
- SGK(11 prodotti)
- Tioredossina(12 prodotti)
- Transferasi(29 prodotti)
- Trasportatore(46 prodotti)
- UGT(4 prodotti)
- Inibitori della xantina ossidasi (XO)(9 prodotti)
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Trovati 9275 prodotti di "Metabolismo"
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Antidiabetic agent 5
CAS:Compound S1 (antidiabetic agent 5) is an antidiabetic agent that effectively inhibits the enzymes α-glucosidase and α-amylase, demonstrating IC50 values of 3.91 µM and 8.89 µM, respectively. It reduces sugar levels and holds potential for type-II diabetes research [1].Formula:C17H15N3O4SColore e forma:SolidPeso molecolare:357.38Etiocholanolone glucuronide
CAS:Etiocholanolone glucuronide (Etio-G) is a metabolite of Etiocholanolone, produced through the catalysis by UDP glucuronosyltransferase in the liver. Etiocholanolone glucuronide shows potential for research in metabolic-related diseases.Formula:C25H38O8Colore e forma:SolidPeso molecolare:466.564Casein kinase 1δ-IN-26
CAS:<p>Casein kinase1δ-IN-26 (compound 505) is a potent inhibitor of casein kinase 1δ. This compound is applicable in research related to neurodegenerative disorders such as Alzheimer’s disease.</p>Formula:C16H13N3O4SColore e forma:SolidPeso molecolare:343.357Nampt-IN-14
CAS:Nampt-IN-14 (example 3) is an effective NAMPT inhibitor with an IC50 of 0.2 nM, suited for use in the synthesis of antibody-drug conjugates (ADCs).Formula:C33H35N7O2Colore e forma:SolidPeso molecolare:561.68RXR antagonist 2
RXR antagonist 2 is a potent antagonist of RXR (Ki: 0.391 μM, Kd: 0.281 μM). RXR antagonist 2 has shown research potential for RXR-related diseases.Formula:C29H35F3N2O3Colore e forma:SolidPeso molecolare:516.6CHI3L1-IN-2
CAS:CHI3L1-IN-2 (Compound 36), a potent inhibitor of CHI3L1 (YKL-40), effectively blocks the interaction between CHI3L1 and heparan sulfate (CHI3L1:HSIII), demonstrating an IC 50 of 26 nM [1].Formula:C26H37ClN4Peso molecolare:441.05NAMPT activator-6
CAS:<p>NAMPT activator-6, a regulatory molecule for the optical control system of NAMPT and NAD+, can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) for light-dependent, reversible regulation of NAMPT and NAD+, thereby reducing toxicity associated with inhibitor-based PS-PROTACs. This enables antitumor activity and in vivo modulation of NAMPT and NAD+ through optical manipulation [1].</p>Formula:C17H21N5O3SColore e forma:SolidPeso molecolare:375.45Z21090
CAS:Z21090 (ZL40) is a highly effective inhibitor of PDE 4, exhibiting an IC 50 value of 37.4 nM, and possesses oral bioavailability. It is significant in the study of alcohol-related diseases [1].Formula:C12H14ClN3O3Colore e forma:SolidPeso molecolare:283.717-Hydroxyrisperidone
CAS:7-Hydroxyrisperidone (7-RispOH) is a metabolite of Risperidone. Risperidone acts as a 5-HT2 receptor blocker, an inhibitor of P-glycoprotein (P-Glycoprotein), and an antagonist of the dopamine D2 receptor.Formula:C23H27FN4O3Colore e forma:SolidPeso molecolare:426.484CIT-ALD
CAS:CIT-ALD is an aldehyde intermediate formed during the metabolism of Citalopram. It has potential applications in the research of neurological disorders.Formula:C18H14FNO2Peso molecolare:295.31UGT1A1-IN-1
CAS:UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].Formula:C22H19NO3Colore e forma:SolidPeso molecolare:345.39AChE/CA I-IN-1
AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.Formula:C14H19NO6SColore e forma:SolidPeso molecolare:329.37ZMC3
CAS:ZMC3 (NSC328784), a zinc chelator, exhibits properties as a zinc metallochaperone. It shows enhanced sensitivity in cells with the p53-R175H mutation and increases the cellular levels of ROS (reactive oxygen species).Formula:C17H20N6SeColore e forma:SolidPeso molecolare:387.34PD-224378
CAS:PD-224378 is the lactam form of glycamine (β-isomer), produced through a Maillard reaction between pregabalin and lactose.Formula:C20H35NO11Colore e forma:SolidPeso molecolare:465.492EB-0156
EB-0156: potent ER α-glucosidase inhibitor, IC50 of 0.0479/ <0.001 μM, N-substituted valerian, broad-spectrum antiviral potential.Formula:C21H32N6O7Colore e forma:SolidPeso molecolare:480.51O-Desmethyl Brinzolamide hydrochloride
CAS:O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Formula:C11H20ClN3O5S3Colore e forma:SolidPeso molecolare:405.94(E)-10-Hydroxynortriptyline maleate
CAS:(E)-10-Hydroxy Nortriptyline maleate, a derivative of antidepressant Nortriptyline, eases depression symptoms.Formula:C23H25NO5Purezza:98%Colore e forma:SolidPeso molecolare:395.455Mucidin
CAS:Mucidin is an antifungal antibiotic that inhibits electron transfer reactions within the mitochondrial respiratory chain's cytochrome bc1 complex.Formula:C16H18O3Peso molecolare:258.311,2-Dipentadecanoyl-rac-glycerol
CAS:1,2-Dipentadecanoyl-rac-glycerol (DG(15:0/15:0/0:0)) is a compound referenced in studies examining the effect of insulin on the content of 1,2-diacylglycerol in rat hearts. Insulin is observed to increase the amount of 1,2-diacylglycerol containing specific fatty acid compositions in the heart, which may be linked to cardiac contractility.Formula:C33H64O5Colore e forma:SolidPeso molecolare:540.86MAGL-IN-19
CAS:MAGL-IN-19 (compound 7o) is a highly effective and selective inhibitor of MAGL.Formula:C21H26F3N3O3Colore e forma:SolidPeso molecolare:425.45
