NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 390 produtos de "NF-κB"
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Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Cor e Forma:SolidPeso molecular:288.82NIK SMI1
CAS:NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).Fórmula:C20H19N3O4Pureza:99.04% - 99.99%Cor e Forma:SolidPeso molecular:365.38Ref: TM-T16290
1mg82,00€5mg173,00€10mg281,00€25mg563,00€50mg885,00€100mg1.425,00€200mg1.948,00€1mL*10mM (DMSO)410,00€Ergolide
CAS:Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.Fórmula:C17H22O5Pureza:99.64%Cor e Forma:SolidPeso molecular:306.35Ref: TM-T13686
1mg71,00€5mg139,00€10mg230,00€25mg374,00€50mg520,00€100mg697,00€1mL*10mM (DMSO)166,00€Naringin dihydrochalcone
CAS:Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.Fórmula:C27H34O14Pureza:99.07% - 99.73%Cor e Forma:Solid PowderPeso molecular:582.55SN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.Fórmula:C131H234N36O31SPureza:99.86%Cor e Forma:SolidPeso molecular:2841.55Methylthiouracil
CAS:Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.Fórmula:C5H6N2OSPureza:99.89% - >99.99%Cor e Forma:Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Peso molecular:142.18IMD-0560
CAS:IMD-0560 is a novel inhibitor of IκB kinase β.Fórmula:C15H8BrF6NO2Pureza:99.51%Cor e Forma:SolidPeso molecular:428.12Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Fórmula:C9H8O4Pureza:99.78% - 99.91%Cor e Forma:White Solid CrystallinePeso molecular:180.16Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Fórmula:C27H30O7Pureza:95.84% - 99.4%Cor e Forma:SolidPeso molecular:466.52Ref: TM-T16324
1mg67,00€5mg167,00€10mg289,00€25mg595,00€50mg820,00€100mg1.108,00€200mg1.440,00€1mL*10mM (DMSO)180,00€Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Fórmula:C7H5NaO3Pureza:99.36% - 99.92%Cor e Forma:White Solid AmorphousPeso molecular:160.11Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Fórmula:C23H34O5Pureza:99.12%Cor e Forma:White-Yellowish To Yellow Powder Solid PowderPeso molecular:390.51DRI-C21045
CAS:Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).Fórmula:C32H24N2O7SPureza:97.20%Cor e Forma:SolidPeso molecular:580.61Asatone
CAS:Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK pathways (ERK, JNK, p38).Fórmula:C24H32O8Pureza:99.84% - 99.92%Cor e Forma:SolidPeso molecular:448.51Ref: TM-T10383
1mg77,00€5mg167,00€10mg260,00€25mg440,00€50mg628,00€100mg872,00€200mg1.153,00€1mL*10mM (DMSO)178,00€Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Fórmula:C14H22N2OPureza:99.95% - >99.99%Cor e Forma:Needles From Benzene Or Alcohol SolidPeso molecular:234.34BAY-985
CAS:BAY-985: potent oral TBK1/IKKε inhibitor; IC50s: TBK1 (2/30 nM), IKKε (2 nM); has antitumor properties.Fórmula:C27H30F3N9OPureza:99.62%Cor e Forma:SolidPeso molecular:553.58Ref: TM-T10477
1mg163,00€5mg334,00€10mg502,00€25mg853,00€50mg1.161,00€100mg1.558,00€1mL*10mM (DMSO)408,00€Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Fórmula:C15H24O5Pureza:98% - 99.41%Cor e Forma:White SolidPeso molecular:284.35Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Fórmula:C19H24ClNO4Pureza:99.43%Cor e Forma:SolidPeso molecular:365.85Mangiferin
CAS:Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.Fórmula:C19H18O11Pureza:99.78% - 99.86%Cor e Forma:Light Yellow PowderPeso molecular:422.34Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:Yellow PowderPeso molecular:446.36Ref: TM-T2775
1g80,00€2g102,00€5g152,00€50mg34,00€100mg49,00€200mg49,00€500mg55,00€1mL*10mM (DMSO)50,00€Articaine hydrochloride
CAS:Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Fórmula:C13H21ClN2O3SPureza:99.76%Cor e Forma:White Crystalline PowderPeso molecular:320.844-Hydroxychalcone
CAS:4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.Fórmula:C15H12O2Pureza:99.75%Cor e Forma:Yellow PowderPeso molecular:224.255-Aminosalicylic Acid
CAS:5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1 (PAK1) and NF-Κb. High-Quality, Low-Cost!Fórmula:C7H7NO3Pureza:98.88% - 99.49%Cor e Forma:Purplish-Tan Solid PowderPeso molecular:153.14Guaiacol
CAS:Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.
Fórmula:C7H8O2Pureza:99.95%Cor e Forma:Colourless To Pale Yellow Solid CrystallinePeso molecular:124.14Oxaprozin
CAS:Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.Fórmula:C18H15NO3Pureza:98.53%Cor e Forma:SolidPeso molecular:293.32Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Fórmula:C28H32N2O7Pureza:99.03% - 99.67%Cor e Forma:SolidPeso molecular:508.56Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Fórmula:C14H23ClN2OPureza:99.81% - 99.92%Cor e Forma:White Crystal PowderPeso molecular:270.798Erdosteine
CAS:Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.Fórmula:C8H11NO4S2Pureza:99.65% - 99.94%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:249.31α-Lipoic Acid
CAS:α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in dietary supplements.Fórmula:C8H14O2S2Pureza:98.39% - 99.83%Cor e Forma:Forms Yellowish Flakes Light Yellow To Yellow PowderPeso molecular:206.33TBK1/IKKε-IN-2
CAS:TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.Fórmula:C26H27N5O3Pureza:98.89%Cor e Forma:SolidPeso molecular:457.52Ref: TM-T15559
1mg52,00€5mg111,00€10mg173,00€25mg278,00€50mg375,00€100mg482,00€1mL*10mM (DMSO)111,00€DCZ0415
CAS:DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders DNA repair and NF-κB activity.Fórmula:C23H20N2O2Pureza:99.34% - 99.95%Cor e Forma:SolidPeso molecular:356.42Ref: TM-T10981
1mg50,00€5mg110,00€10mg178,00€25mg334,00€50mg505,00€100mg707,00€200mg973,00€1mL*10mM (DMSO)119,00€Metaxalone
CAS:Metaxalone, sold as Skelaxin by King Pharmaceuticals, is a muscle relaxant for pain from strains and sprains.Fórmula:C12H15NO3Pureza:98.84% - 99.94%Cor e Forma:White To Almost White Crystalline Powder SolidPeso molecular:221.25Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Cor e Forma:Minute Brownish-Yellow CrystalsPeso molecular:398.39DMAPT
CAS:DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.Fórmula:C17H27NO3Pureza:99.91%Cor e Forma:SolidPeso molecular:293.4CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Fórmula:C33H45F3N2O3Pureza:95.61% - 99.59%Cor e Forma:SolidPeso molecular:574.72Ref: TM-T13604
1mg66,00€2mg96,00€5mg144,00€10mg241,00€25mg485,00€50mg700,00€100mg982,00€500mg1.953,00€1mL*10mM (DMSO)177,00€Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFórmula:C13H8O3Pureza:99.45%Cor e Forma:SolidPeso molecular:212.2Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFórmula:C7H8N4O2Pureza:99.65% - 99.98%Cor e Forma:White Solid PowderPeso molecular:180.16Theophylline monohydrate
CAS:Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calciumFórmula:C7H8N4O2·H2OPureza:99.78%Cor e Forma:SolidPeso molecular:198.18Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.41(E/Z)-BCI
CAS:(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFórmula:C22H23NOPureza:99.94%Cor e Forma:SolidPeso molecular:317.42Ref: TM-T11139
1mg80,00€5mg155,00€10mg283,00€25mg452,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)170,00€SN50 TFA
SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.Fórmula:C129H230N36O29S·XCF3COOHCor e Forma:SolidPeso molecular:2781.5 (free base)SU1261
SU1261, an IKK inhibitor, exhibits Ki values of 10 nM for IKKα and 680 nM for IKKβ. It effectively inhibits non-canonical NF-κB signaling in U2OS osteosarcoma cells.Cor e Forma:Odour SolidNF-κB-IN-10
NF-κB-IN-10 (compound E1) is an inhibitor of NF-κB that mitigates heart failure symptoms through the modulation of the Nrf2/NF-κB signaling pathway, alleviatingFórmula:C26H30N2O4Pureza:98%Cor e Forma:SolidPeso molecular:434.53NBD peptide
CAS:NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.Fórmula:C62H88N14O20Cor e Forma:SolidPeso molecular:1349.44SjDX5-271
CAS:SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.Fórmula:C137H215N47O49SCor e Forma:SolidPeso molecular:3336.52Mitogen-activated protein kinase 1
CAS:Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases.Pureza:98%Cor e Forma:SolidAnti-inflammatory agent 48
Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatoryFórmula:C24H21Cl2NO3Pureza:98%Cor e Forma:SolidPeso molecular:442.33HOIPIN-1
CAS:HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-Fórmula:C17H13NaO4Pureza:98.65%Cor e Forma:SoildPeso molecular:304.27R-HP210
R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54PS 1145 dihydrochloride
CAS:IκB kinase (IKK) inhibitorFórmula:C17H13Cl3N4OPureza:98%Cor e Forma:SolidPeso molecular:395.67Nasunin
CAS:Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.Fórmula:C42H47ClO23Cor e Forma:SolidPeso molecular:955.26Sanggenon A
CAS:Sanggenon A (Sanggenone A) exhibits anti-inflammatory properties by modulating the NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells, and itFórmula:C25H24O7Pureza:98%Cor e Forma:SolidPeso molecular:436.45Anti-inflammatory agent 60
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-cateninPureza:98%Cor e Forma:Odour SolidIKK-IN-3
CAS:IKK-IN-3: potent IKK2 inhibitor (IC50=19nM), affects IKK1(IC50=400nM).Fórmula:C17H17N5SCor e Forma:SolidPeso molecular:323.42NF-κΒ activator 1
CAS:NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.Fórmula:C16H11FN2O2SPureza:99.58%Cor e Forma:SolidPeso molecular:314.33Ref: TM-T39965
1mg95,00€5mg202,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€500mg2.213,00€1mL*10mM (DMSO)224,00€CAY10657
CAS:CAY10657 has a wide range of applications in life science related research.
Fórmula:C17H20N4O3SCor e Forma:SolidPeso molecular:360.43PROTAC STING degrader-3
PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.Cor e Forma:Odour SolidLemnalol
CAS:Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.Fórmula:C15H24OPureza:98%Cor e Forma:SolidPeso molecular:220.35Cyclo(L-Pro-L-Val)
CAS:Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.
Fórmula:C10H16N2O2Pureza:98.18%Cor e Forma:SolidPeso molecular:196.25Helenalin
CAS:Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.Fórmula:C15H18O4Pureza:98%Cor e Forma:SolidPeso molecular:262.3OT-551 HCl
CAS:OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macularFórmula:C13H24ClNO3Pureza:98.89%Cor e Forma:SolidPeso molecular:277.79Ref: TM-T28273L
1mg109,00€5mg233,00€10mg344,00€25mg532,00€50mg760,00€100mg1.054,00€200mg1.414,00€1mL*10mM (DMSO)279,00€Aloenin aglycone
CAS:Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate.Fórmula:C13H12O5Pureza:98%Cor e Forma:SolidPeso molecular:248.23NF-κB-IN-12
NF-κB-IN-12 (compound 3h) serves as a potent inhibitor of NF-κB, exhibiting an IC50 value of 1.02 μM. It is applicable for research in acute lung injury [1].Fórmula:C30H26N6O5SPureza:98%Cor e Forma:SolidPeso molecular:582.63MJ210
MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.Cor e Forma:Odour SolidHS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
Fórmula:C17H16N4O3Pureza:98.62%Cor e Forma:SolidPeso molecular:324.33IKKγ NBD Inhibitory Peptide
CAS:A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF
Fórmula:C170H259N49O42S1Pureza:98%Cor e Forma:SolidPeso molecular:3693.3CAY10512
CAS:CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.Fórmula:C15H13FOCor e Forma:SolidPeso molecular:228.26612-Oxo phytodienoic acid
CAS:12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.
Fórmula:C18H28O3Pureza:98%Cor e Forma:SolidPeso molecular:292.41Anti-inflammatory agent 51
CAS:Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury and ulcerative colitis.Fórmula:C22H22N6O6SPureza:99.76%Cor e Forma:SoildPeso molecular:498.51NF-κB Signaling Compound Library
A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;Cor e Forma:Odour SolidRef: TM-L3800
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarMurrayafoline A
CAS:Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.Fórmula:C14H13NOCor e Forma:SolidPeso molecular:211.264EN450
CAS:EN450 is a targeted cysteine degrader of NF-κB with antiproliferative activity and potential anticancer activity for the study of leukemia.Fórmula:C11H13ClN2O3SPureza:98.39%Cor e Forma:SoildPeso molecular:288.75Ref: TM-T77525
2mg44,00€5mg64,00€10mg96,00€25mg187,00€50mg288,00€100mg416,00€200mg583,00€1mL*10mM (DMSO)71,00€Coronalolic acid
CAS:Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced NF-κB activity and NO production.Fórmula:C30H46O4Pureza:98%Cor e Forma:SolidPeso molecular:470.68NF-κB-IN-9
NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dualFórmula:C62H50N4O4SCor e Forma:SolidPeso molecular:947.15Ginger extract
CAS:Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).
Cor e Forma:Solid3-(2-Hydroxyethyl) thio withaferin A
3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.Fórmula:C30H44O7SCor e Forma:SolidPeso molecular:548.73(R)-(-)-Ibuprofen
CAS:(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.Fórmula:C13H18O2Pureza:99.86%Cor e Forma:SolidPeso molecular:206.28Mesalamine impurity P
CAS:Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.Fórmula:C13H11NO6SCor e Forma:SolidPeso molecular:309.30Licoagrochalcone C
CAS:Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.Fórmula:C21H22O5Cor e Forma:SolidPeso molecular:354.47-O-Methylaloeasinol
CAS:7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.Fórmula:C20H26O9Cor e Forma:SolidPeso molecular:410.419SN50M
CAS:SN50M (NF-κB Control) is a synthetic peptide containing a hydrophobic region and mutant nuclear localization sequences that can enter cells.Fórmula:C123H215N33O30SCor e Forma:SolidPeso molecular:2668.29Anti-inflammatory agent 7
Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.Fórmula:C36H40N4O9Cor e Forma:SolidPeso molecular:672.72Gliotoxin
CAS:Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.Fórmula:C13H14N2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:326.39IVMT-Rx-3
IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.Fórmula:C69H90F3N13O24Pureza:98%Cor e Forma:SoildPeso molecular:1542.54N-Acetyldopamine dimer-2
CAS:Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.Fórmula:C20H20N2O6Cor e Forma:SolidPeso molecular:384.38Apo A-I mimetic 5A peptide
Apo A-I mimetic 5A peptide is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). It facilitates the efflux of cholesterol from inside cells, helping to reduce intracellular cholesterol accumulation. Additionally, Apo A-I mimetic 5A peptide exhibits anti-inflammatory properties, lowering inflammatory markers in blood and tissues. This peptide is used in cardiovascular disease research.Fórmula:C197H295N47O56Peso molecular:4215.16808Transcription Factor-Targeted Compound Library
Well-chosen xnum compounds with unique structures targeting transcription factor;Cor e Forma:Odour SolidRef: TM-L1380
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarSiegesbeckialide I
Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.Fórmula:C20H28O6Cor e Forma:SolidPeso molecular:364.43Halleridone
CAS:Halleridone, a natural product, is identified in Teuanchum decipiens and Abeliophyllum distichum.Fórmula:C8H10O3Cor e Forma:SolidPeso molecular:154.165TBK1/IKKε-IN-6
CAS:TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.Fórmula:C31H36F2N8O4Cor e Forma:SolidPeso molecular:622.678(−)-N-Hydroxyapiosporamide
CAS:(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both in vitro and in vivo.Fórmula:C24H31NO7Pureza:98%Cor e Forma:SolidPeso molecular:445.51Pratensein
CAS:Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.Fórmula:C16H12O6Pureza:99.90%Cor e Forma:SolidPeso molecular:300.26Diprovocim-1
CAS:Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 & CTLs against tumors with anti-PD-L1 in mice.Fórmula:C56H56N6O6Cor e Forma:SolidPeso molecular:909.1Eupenicisirenin C
CAS:Eupenicisirenin C (compound 1), a sirenin derivative, exhibits strong NF-κB inhibitory activities and suppresses the cGAS-STING pathway. Additionally, Eupenicisirenin C inhibits RANKL-induced osteoclast differentiation in bone marrow macrophage cells [1].Fórmula:C13H18O4Cor e Forma:SolidPeso molecular:238.28Antidesmone
CAS:Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.Fórmula:C19H29NO3Pureza:98%Cor e Forma:SolidPeso molecular:319.44MRT67307
CAS:Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Fórmula:C26H36N6O2Pureza:99.25% - 99.84%Cor e Forma:SolidPeso molecular:464.6NLRP3-IN-51
NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.Cor e Forma:Odour SolidAnti-osteoporosis agent-8
Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.Fórmula:C18H19F3N2O2SePeso molecular:432.05638LY2409881
CAS:LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.Fórmula:C24H29ClN6OSCor e Forma:SolidPeso molecular:485.05Anti-osteoporosis agent-4
Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.Fórmula:C26H26ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:560.02Sootepin D
CAS:Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.Fórmula:C31H48O4Pureza:98%Cor e Forma:SolidPeso molecular:484.71Narlumosbart
CAS:Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].Pureza:98%Cor e Forma:LiquidCTP-NBD
CAS:CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].Fórmula:C121H194N46O32Pureza:98%Cor e Forma:SolidPeso molecular:2805.1217-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS:DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).
Fórmula:C22H32O3Cor e Forma:SolidPeso molecular:344.495R1-ICR-5
CAS:R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.Fórmula:C54H70N8O7S2Cor e Forma:SolidPeso molecular:1007.31BIZ 114
CAS:BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.Fórmula:C24H40O3Cor e Forma:SolidPeso molecular:376.57Hesperidin methylchalcone
CAS:Hesperidin methylchalcone, from Citrus, is a potent antioxidant that inhibits NF-κB to alleviate gout arthritis in mice.Fórmula:C29H36O15Pureza:99.53%Cor e Forma:Yellow PowderPeso molecular:624.59RS 09
CAS:TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.Fórmula:C31H49N9O9Pureza:98%Cor e Forma:SolidPeso molecular:691.78SEMBL
CAS:SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.Fórmula:C12H11NO4Pureza:98%Cor e Forma:SolidPeso molecular:233.22DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Fórmula:C26H35N7O5Cor e Forma:SolidPeso molecular:525.6ML 120B dihydrochloride
CAS:MLN120B dihydrochloride: oral IKKβ inhibitor with 60 nM IC50, suppresses myeloma growth, used in arthritis research.Fórmula:C19H17Cl3N4O2Cor e Forma:SolidPeso molecular:439.72Theaflavin 3,3′-digallate
CAS:Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFórmula:C43H32O20Pureza:98.71% - 99.86%Cor e Forma:SolidPeso molecular:868.70Ref: TM-T5429
1mg87,00€5mg169,00€10mg268,00€25mg462,00€50mg647,00€100mg873,00€200mg1.153,00€1mL*10mM (DMSO)268,00€Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Fórmula:C20H18O11Pureza:97.02% - 99.94%Cor e Forma:White PowderPeso molecular:434.35Ref: TM-T6S0117
1mg55,00€5mg92,00€10mg152,00€25mg268,00€50mg395,00€100mg583,00€200mg832,00€1mL*10mM (DMSO)105,00€Sulfuretin
CAS:Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.
Fórmula:C15H10O5Pureza:98.91% - 99.86%Cor e Forma:SolidPeso molecular:270.24BEC hydrochloride
CAS:BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.Fórmula:C5H12BNO4S·ClHPureza:98.65% - 99.28%Cor e Forma:SolidPeso molecular:229.49Ref: TM-T6779
1mg39,00€5mg88,00€10mg153,00€25mg283,00€50mg464,00€100mg663,00€200mg919,00€1mL*10mM (DMSO)88,00€(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Fórmula:C16H16N6OPureza:98.44%Cor e Forma:SolidPeso molecular:308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€1mL*10mM (DMSO)105,00€Parthenolide
CAS:Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Fórmula:C15H20O3Pureza:98.19% - 99.46%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:248.32GSK8612
CAS:GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .Fórmula:C17H17BrF3N7O2SPureza:99.68% - 99.99%Cor e Forma:SolidPeso molecular:520.33(E/Z)-IT-603
CAS:(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.Fórmula:C11H9BrN2O3SPureza:99.35%Cor e Forma:SolidPeso molecular:329.17Ref: TM-T8799
1mg56,00€5mg119,00€10mg192,00€25mg356,00€50mg565,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)133,00€IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFórmula:C22H23N5O8Pureza:97.73%Cor e Forma:SolidPeso molecular:485.45Ref: TM-T9010
1mg40,00€5mg96,00€10mg135,00€25mg226,00€50mg320,00€100mg434,00€200mg602,00€1mL*10mM (DMSO)131,00€Ginsenoside Rg6
CAS:Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cellsFórmula:C42H70O12Pureza:97.34%Cor e Forma:SolidPeso molecular:767CORM-3
CAS:CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.Fórmula:C5H4ClNO5RuPureza:98%Cor e Forma:SolidPeso molecular:294.61anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFórmula:C45H74O18Pureza:99.06% - 99.11%Cor e Forma:SolidPeso molecular:903.06Dehydroevodiamine
CAS:Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressantFórmula:C19H15N3OPureza:99.54%Cor e Forma:SolidPeso molecular:301.34Galloylpaeoniflorin
CAS:Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.Fórmula:C30H32O15Pureza:99.82%Cor e Forma:SolidPeso molecular:632.572-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.
Fórmula:C11H10N2OSPureza:99.48%Cor e Forma:SolidPeso molecular:218.27Vanillic Acid
CAS:Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.Fórmula:C8H8O4Pureza:99.82%Cor e Forma:White Odourless Crystals Or PowderPeso molecular:168.15Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFórmula:C19H18NO4Pureza:98.08% - 99.18%Cor e Forma:SolidPeso molecular:324.351-Caffeoylquinic acid
CAS:1-Caffeoylquinic acid: a lignin precursor with anti-influenza, antioxidant properties, and moderates post-meal glucose release.Fórmula:C16H18O9Pureza:99.15% - 99.16%Cor e Forma:SolidPeso molecular:354.31Stachydrine
CAS:Stachydrine, found in leonurus herb, aids blood flow, blocks NF-κB pathway, and indicates citrus intake.Fórmula:C7H13NO2Pureza:99.94% - ≥95%Cor e Forma:SolidPeso molecular:143.18Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Fórmula:C42H72O14Pureza:99.42% - 99.65%Cor e Forma:SolidPeso molecular:801.01Berbamine dihydrochloride
CAS:Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Fórmula:C37H42Cl2N2O6Pureza:95% - 99.99%Cor e Forma:SolidPeso molecular:681.65Myrcene
CAS:Myrcene is a terpene that has been found in Cannabis and has antioxidative properties.Fórmula:C10H16Pureza:98%Cor e Forma:Colourless Slightly Amber Coloured LiquidPeso molecular:136.23Esculentoside A
CAS:Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.Fórmula:C42H66O16Pureza:98% - 99.85%Cor e Forma:SolidPeso molecular:826.96Forsythoside B
CAS:Forsythoside B inhibits LPS, NF-κB, inflammation, offers neuroprotection, reduces ischemia injury, and has antioxidant and antisepsis effects.Fórmula:C34H44O19Pureza:98% - 99.81%Cor e Forma:SolidPeso molecular:756.70Zingerone
CAS:Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale with potent anti-inflammatory, antidiabetic and anti-tumor properties.Fórmula:C11H14O3Pureza:99.38% - 99.85%Cor e Forma:Clear Slightly Yellow LiquidPeso molecular:194.23Necrostatin-34
CAS:Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying aFórmula:C18H16N4O2S2Pureza:98.66% - 98.8%Cor e Forma:SolidPeso molecular:384.48Ref: TM-T9095
1mg52,00€5mg116,00€10mg170,00€25mg305,00€50mg442,00€100mg615,00€200mg832,00€1mL*10mM (DMSO)135,00€WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Fórmula:C28H38O6Pureza:97.41% - 99.99%Cor e Forma:SolidPeso molecular:470.60Ref: TM-T5687
1mg80,00€5mg251,00€10mg371,00€25mg620,00€50mg880,00€100mg1.189,00€500mg2.385,00€1mL*10mM (DMSO)288,00€Ginsenoside Rb3
CAS:Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.Fórmula:C53H90O22Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:1079.27Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Fórmula:C10H7N3O4SPureza:98.89% - 99.28%Cor e Forma:SolidPeso molecular:265.25Cyclo(his-pro)
CAS:Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.Fórmula:C11H14N4O2Pureza:99.87%Cor e Forma:SolidPeso molecular:234.25Asperulosidic acid
CAS:Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.Fórmula:C18H24O12Pureza:99.47%Cor e Forma:SolidPeso molecular:432.38Ref: TM-TN1410
1mg120,00€2mg170,00€5mg260,00€10mg432,00€25mg708,00€50mg964,00€100mg1.288,00€1mL*10mM (DMSO)286,00€18α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Fórmula:C30H46O4Pureza:98.54% - 99.68%Cor e Forma:SolidPeso molecular:470.68OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Fórmula:C44H70O16Pureza:99.46% - ≥95%Cor e Forma:SolidPeso molecular:855.02Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Fórmula:C21H22O11Pureza:98.63% - 99.54%Cor e Forma:SolidPeso molecular:450.39CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Fórmula:C20H28O3Pureza:97.06% - 99.08%Cor e Forma:SolidPeso molecular:316.43TOMATIDINE HYDROCHLORIDE
CAS:Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.Fórmula:C27H46ClNO2Pureza:99.75% - ≥95%Cor e Forma:SolidPeso molecular:452.11Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Fórmula:C13H15NO2SPureza:99.76% - 99.94%Cor e Forma:White SolidPeso molecular:249.33Ref: TM-T1934
2mg34,00€5mg48,00€10mg63,00€25mg80,00€50mg117,00€100mg187,00€200mg243,00€1mL*10mM (DMSO)58,00€Ginsenoside Rg2
CAS:Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.Fórmula:C42H72O13Pureza:99.77% - 99.78%Cor e Forma:SolidPeso molecular:785.01Ref: TM-T2873
2mg37,00€5mg52,00€10mg88,00€25mg131,00€50mg188,00€100mg279,00€500mg658,00€1mL*10mM (DMSO)87,00€Dehydrodiisoeugenol
CAS:Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.Fórmula:C20H22O4Pureza:99.97%Cor e Forma:SolidPeso molecular:326.39Stachydrine Hydrochloride
CAS:Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.Fórmula:C7H14ClNO2Pureza:99.53% - 99.71%Cor e Forma:Light Yellow PastePeso molecular:179.64Ginsenoside Rg1
CAS:Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Fórmula:C42H72O14Pureza:99% - 99.92%Cor e Forma:White Crystalline PowderPeso molecular:801.01CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Fórmula:C21H25ClN2O2Pureza:99.35% - 99.86%Cor e Forma:SolidPeso molecular:372.88Kaempferol-3-O-glucorhamnoside
CAS:Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPKFórmula:C27H30O15Pureza:96.96% - 98.17%Cor e Forma:SolidPeso molecular:594.5Ref: TM-T5S0089
1mg48,00€5mg92,00€10mg136,00€25mg215,00€50mg323,00€100mg469,00€200mg647,00€1mL*10mM (DMSO)122,00€Saikosaponin D
CAS:Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.Fórmula:C42H68O13Pureza:98.34% - 99.73%Cor e Forma:White PowderPeso molecular:780.98IMD-0354
CAS:IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.Fórmula:C15H8ClF6NO2Pureza:99.65% - 99.98%Cor e Forma:SolidPeso molecular:383.67Ref: TM-T6141
2mg46,00€5mg63,00€10mg87,00€25mg155,00€50mg210,00€100mg294,00€500mg713,00€1mL*10mM (DMSO)65,00€Phellodendrine
CAS:Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.Fórmula:C20H24NO4Pureza:98.7% - 99.94%Cor e Forma:SolidPeso molecular:342.41Ref: TM-T6S0781
2mg40,00€5mg56,00€10mg80,00€25mg114,00€50mg167,00€100mg240,00€200mg355,00€1mL*10mM (DMSO)73,00€Muscone
CAS:Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.Fórmula:C16H30OPureza:98.97% - ≥98%Cor e Forma:Colourless Liquid LiquidPeso molecular:238.41BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFórmula:C15H15NO2SPureza:99.73%Cor e Forma:SolidPeso molecular:273.35Ref: TM-T8705
1mg50,00€5mg110,00€10mg170,00€25mg323,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)102,00€Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.
Fórmula:C36H49NO12Pureza:98% - 99.84%Cor e Forma:SolidPeso molecular:687.773'-Sialyllactose
CAS:3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.Fórmula:C23H39NO19Cor e Forma:SolidPeso molecular:633.55EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Fórmula:C18H18ClMnN2O4Pureza:98.39%Cor e Forma:SolidPeso molecular:416.74Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Fórmula:C25H24O6Pureza:98.68% - 99.8%Cor e Forma:SolidPeso molecular:420.45QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Fórmula:C22H20N4OPureza:99.17% - 99.18%Cor e Forma:White SolidPeso molecular:356.42Ref: TM-T6204
1mg40,00€2mg54,00€5mg88,00€10mg133,00€25mg178,00€50mg313,00€100mg465,00€200mg673,00€1mL*10mM (DMSO)87,00€BMS-345541
CAS:BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.Fórmula:C14H17N5Pureza:99.36% - 99.74%Cor e Forma:SolidPeso molecular:255.32Myrislignan
CAS:Myrislignan exhibits anti-inflammatory, anti-cancer properties, hinders NF-κB pathway, curbs A549 cell growth, and triggers apoptosis and cell cycle arrest.Fórmula:C21H26O6Pureza:98.77% - 99.41%Cor e Forma:SolidPeso molecular:374.43Ref: TM-T4S1540
1mg44,00€5mg87,00€10mg137,00€25mg236,00€50mg385,00€100mg560,00€1mL*10mM (DMSO)102,00€NF-κB-IN-1
CAS:NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathwayFórmula:C31H30O8Pureza:99.03%Cor e Forma:SolidPeso molecular:530.57Ref: TM-T9105
1mg166,00€5mg341,00€10mg550,00€25mg898,00€50mg1.216,00€100mg1.644,00€1mL*10mM (DMSO)398,00€Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Fórmula:C19H17ClN2O3Pureza:98.42% - 98.84%Cor e Forma:SolidPeso molecular:356.8Sulindac sodium
CAS:Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.Fórmula:C20H16FNaO3SCor e Forma:SolidPeso molecular:378.39Articaine
CAS:Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-Fórmula:C13H20N2O3SCor e Forma:SolidPeso molecular:284.372,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Fórmula:C8H8O3Pureza:99.75%Cor e Forma:Yellow PowderPeso molecular:152.152-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Fórmula:C15H12O2Pureza:99.6%Cor e Forma:SolidPeso molecular:224.25Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Fórmula:C48H82O18Pureza:99.13% - 99.92%Cor e Forma:SolidPeso molecular:947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€Ref: TM-T5S0754
5mg46,00€10mg58,00€25mg92,00€50mg137,00€100mg200,00€200mg295,00€1mL*10mM (DMSO)49,00€Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Fórmula:C37H40N2O6Pureza:98.92% - 99.67%Cor e Forma:White Crystal PowderPeso molecular:608.72Dauricine
CAS:1.Fórmula:C38H44N2O6Pureza:99.24% - 99.75%Cor e Forma:White PowderPeso molecular:624.77Dendrophenol
CAS:Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.Fórmula:C17H20O5Pureza:98.2% - 99.36%Cor e Forma:SolidPeso molecular:304.34Ref: TM-T3S1707
1mg99,00€2mg138,00€5mg215,00€10mg319,00€25mg530,00€50mg755,00€100mg1.018,00€1mL*10mM (DMSO)234,00€SC-514
CAS:SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
Fórmula:C9H8N2OS2Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:224.3yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Fórmula:C15H14O4Pureza:98.82% - 99.55%Cor e Forma:Pale Yellow PowderPeso molecular:258.27Ref: TM-T3S0738
1mg70,00€5mg135,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€1mL*10mM (DMSO)177,00€Iron sucrose
CAS:Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.Fórmula:C18H24Fe2O24Pureza:99.97%Cor e Forma:SolidPeso molecular:736.1Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Fórmula:C16H18O9Pureza:99.12% - 99.54%Cor e Forma:White PowderPeso molecular:354.31Ref: TM-T6S1538
1mg34,00€5mg71,00€10mg90,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€1mL*10mM (DMSO)77,00€Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.
Fórmula:C20H18O6Pureza:99.81%Cor e Forma:Off White PowderPeso molecular:354.35Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Fórmula:C15H20O3Pureza:98% - 99.37%Cor e Forma:SolidPeso molecular:248.32Ref: TM-T5688
1mg44,00€5mg113,00€10mg177,00€25mg299,00€50mg447,00€100mg623,00€500mg1.305,00€1mL*10mM (DMSO)124,00€Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Fórmula:C21H22O5Pureza:99.03% - 99.9%Cor e Forma:SolidPeso molecular:354.4Nitidine chloride
CAS:1.Fórmula:C21H18ClNO4Pureza:96.59% - 99.55%Cor e Forma:SolidPeso molecular:383.82Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Fórmula:C27H30O14Pureza:98.11% - 98.58%Cor e Forma:SolidPeso molecular:578.52Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Fórmula:C54H92O23Pureza:99.12% - 99.76%Cor e Forma:SolidPeso molecular:1109.29Convallatoxin
CAS:Convallatoxin is a natural product.Fórmula:C29H42O10Pureza:99.27% - 99.53%Cor e Forma:Prisms From Methanol + Ether SolidPeso molecular:550.64Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Fórmula:C24H30O14Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:542.49Ref: TM-T4S2326
1mg96,00€5mg264,00€10mg415,00€25mg677,00€50mg935,00€100mg1.254,00€500mg2.527,00€1mL*10mM (DMSO)315,00€Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Cor e Forma:Yellow SolidPeso molecular:384.24Ref: TM-T2399
5mg50,00€10mg60,00€25mg75,00€50mg92,00€100mg137,00€200mg213,00€500mg353,00€1mL*10mM (DMSO)50,00€Benzoyloxypaeoniflorin
CAS:Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.Fórmula:C30H32O13Pureza:98.52% - 99.96%Cor e Forma:SolidPeso molecular:600.57Ref: TM-T4S1658
1mg120,00€5mg281,00€10mg409,00€25mg660,00€50mg888,00€100mg1.224,00€1mL*10mM (DMSO)358,00€Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFórmula:C5H12N2S2Pureza:98% - >99.99%Cor e Forma:Off-White To Pale Yellow CrystalsPeso molecular:164.29Sodium Aescinate
CAS:Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.Fórmula:C54H83NaO23Pureza:95.17%Cor e Forma:SolidPeso molecular:1123.21Specnuezhenide
CAS:Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.Fórmula:C31H42O17Pureza:98% - 99.93%Cor e Forma:SolidPeso molecular:686.66Ref: TM-T3803
2mg34,00€5mg50,00€10mg80,00€25mg152,00€50mg219,00€100mg319,00€200mg474,00€1mL*10mM (DMSO)77,00€γ-Tocotrienol
CAS:γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.Fórmula:C28H42O2Pureza:97.27% - 98.13%Cor e Forma:SolidPeso molecular:410.63Ref: TM-T19768
1mg44,00€2mg58,00€5mg96,00€10mg137,00€25mg224,00€50mg333,00€100mg489,00€200mg705,00€1mL*10mM (DMSO)92,00€Ginsenoside Rk3
CAS:Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.Fórmula:C36H60O8Pureza:99.88%Cor e Forma:SolidPeso molecular:620.86Ref: TM-T6S1495
1mg80,00€5mg169,00€10mg241,00€25mg404,00€50mg597,00€100mg850,00€1mL*10mM (DMSO)268,00€MLN120B
CAS:MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).Fórmula:C19H15ClN4O2Pureza:98.92%Cor e Forma:SolidPeso molecular:366.8Ref: TM-TQ0306
1mg50,00€2mg66,00€5mg90,00€10mg152,00€25mg313,00€50mg537,00€100mg735,00€1mL*10mM (DMSO)110,00€PTP1B-IN-1
CAS:PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)Fórmula:C8H8N2O3SPureza:99.27%Cor e Forma:SolidPeso molecular:212.23MD2-TLR4-IN-1
CAS:MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.Fórmula:C22H14Cl2N4OPureza:97.74%Cor e Forma:SolidPeso molecular:421.28Ref: TM-T7672
1mg58,00€5mg128,00€10mg200,00€25mg344,00€50mg482,00€100mg637,00€200mg858,00€1mL*10mM (DMSO)141,00€Rubiadin-1-methyl ether
CAS:Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.
Fórmula:C16H12O4Pureza:98.32%Cor e Forma:SolidPeso molecular:268.26Rhynchophylline
CAS:Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.Fórmula:C22H28N2O4Pureza:99.44% - 99.98%Cor e Forma:Red Brown Or White Fine PowderPeso molecular:384.47
