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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5400 produtos de "Neurociência"

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  • Aβ42 agonist-1
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    Aβ42 agonist-1

    CAS:
    <p>Aβ42 agonist-1 is a small molecule compound with anti-cancer activity and NF-κB inhibitory properties, inducing Aβ42 aggregation.</p>
    Fórmula:C15H11NO2
    Pureza:99.77%
    Cor e Forma:Solid
    Peso molecular:237.25

    Ref: TM-T85792

  • ZK 93426 hydrochloride
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    ZK 93426 hydrochloride

    CAS:
    <p>benzodiazepine receptor antagonist,competitive</p>
    Fórmula:C18H21ClN2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:348.82

    Ref: TM-T23562

  • Flucopride
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    Flucopride

    CAS:
    <p>Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.</p>
    Fórmula:C22H33FN2O2
    Cor e Forma:Solid
    Peso molecular:376.51

    Ref: TM-T201815

  • AGH-107
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    AGH-107

    CAS:
    <p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>
    Fórmula:C13H12IN3
    Cor e Forma:Solid
    Peso molecular:337.16

    Ref: TM-T201735

  • ASP-2205
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    ASP-2205

    CAS:
    <p>ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.</p>
    Fórmula:C19H28N2O
    Cor e Forma:Solid
    Peso molecular:300.44

    Ref: TM-T201450

  • U92016A hydrochloride
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    U92016A hydrochloride

    CAS:
    <p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>
    Fórmula:C19H26ClN3
    Cor e Forma:Solid
    Peso molecular:331.89

    Ref: TM-T60990

  • Logotipo do CymitQuimica
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    Aβ-IN-2

    <p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>
    Fórmula:C37H51NO
    Cor e Forma:Solid
    Peso molecular:525.81

    Ref: TM-T63689

  • YM-31636 free base
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    YM-31636 free base

    CAS:
    <p>YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.</p>
    Fórmula:C14H11N3S
    Cor e Forma:Solid
    Peso molecular:253.32

    Ref: TM-T201587

  • Logotipo do CymitQuimica
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    Monoamine Oxidase B inhibitor 1

    <p>Potent, selective MAO-B inhibitor; reversible; oral; crosses BBB; IC50=0.02 nM; potential for Parkinson's research.</p>
    Fórmula:C18H15FO3
    Cor e Forma:Solid
    Peso molecular:298.31

    Ref: TM-T60656

  • Revexepride
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    Revexepride

    CAS:
    <p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>
    Fórmula:C21H32ClN3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:425.95

    Ref: TM-T16737

  • Fletazepam
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    Fletazepam

    CAS:
    <p>Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.</p>
    Fórmula:C17H13ClF4N2
    Cor e Forma:Solid
    Peso molecular:356.74

    Ref: TM-T201147

  • F 14679
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    F 14679

    CAS:
    <p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>
    Fórmula:C21H25ClF2N4O
    Pureza:99.09%
    Cor e Forma:Solid
    Peso molecular:422.9

    Ref: TM-T62269

  • Logotipo do CymitQuimica
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    AChE/BChE-IN-19

    CAS:
    <p>AChE/BChE-IN-19 (compound 12) is a nicotinic hydrazine derivative that acts as an inhibitor of AChE (IC50=21.45 nM) and BChE (IC50=18.42 nM), and it is applicable in Alzheimer's disease research.</p>
    Fórmula:C26H22N4O3
    Peso molecular:438.48

    Ref: TM-T209831

  • VU6016235
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    VU6016235

    CAS:
    <p>VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.</p>
    Fórmula:C21H22N4OS
    Cor e Forma:Solid
    Peso molecular:378.49

    Ref: TM-T201326

  • RO-1-5237
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    RO-1-5237

    CAS:
    <p>RO-1-5237, a cholinergic compound and a metabolic product of Pyridostigmine Bromide, is utilized in research for myasthenia gravis.</p>
    Fórmula:C6H8BrNO
    Cor e Forma:Solid
    Peso molecular:190.04

    Ref: TM-T200816

  • Logotipo do CymitQuimica
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    MAO-B-IN-28

    CAS:
    <p>MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 value of 1.9±0.5 nM, potentially serving as a candidate molecule for neurodegenerative disease research.</p>
    Fórmula:C19H10F3NO4S
    Peso molecular:405.35

    Ref: TM-T208337

  • LY 541850
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    LY 541850

    CAS:
    <p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>
    Fórmula:C9H13NO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:199.2

    Ref: TM-T11906

  • BRD0418
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    BRD0418

    CAS:
    <p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>
    Fórmula:C29H32N2O5
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:488.57

    Ref: TM-T30577

  • Logotipo do CymitQuimica
    Targetmol
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    CaMKIIα-IN-1

    <p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>
    Fórmula:C14H11ClO4
    Cor e Forma:Solid
    Peso molecular:278.69

    Ref: TM-T60515

  • Zanapezil fumarate
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    Zanapezil fumarate

    CAS:
    <p>Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.</p>
    Fórmula:C29H36N2O5
    Cor e Forma:Solid
    Peso molecular:492.61

    Ref: TM-T29203