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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5400 produtos de "Neurociência"

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  • Aβ-IN-2


    <p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>
    Fórmula:C37H51NO
    Cor e Forma:Solid
    Peso molecular:525.81
  • AChE-IN-5


    <p>AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.</p>
    Fórmula:C38H45N5O
    Cor e Forma:Solid
    Peso molecular:587.8
  • Rocavorexant

    CAS:
    <p>Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.</p>
    Fórmula:C18H19F3N8O
    Cor e Forma:Solid
    Peso molecular:420.392
  • COX-2-IN-47

    CAS:
    <p>COX-2-IN-47 (compound 6c) is a selective inhibitor of COX-2, exhibiting an IC50 of 0.03 μM. This compound also displays antiedema activity.</p>
    Fórmula:C18H18N2O4
    Cor e Forma:Solid
    Peso molecular:326.35
  • FCOB02

    CAS:
    <p>FCOB02 is a monoamine oxidase B (MAO-B) ligand. It can be labeled as [18F]FCOB02, serving as a 4-methylcoumarin-like targeting probe. [18F]FCOB02 demonstrates high affinity for MAO-B, with an IC50 of 10.68 nM. It is utilized for specific imaging and quantitative analysis of MAO-B in vivo.</p>
    Fórmula:C16H12FNO3
    Cor e Forma:Solid
    Peso molecular:285.27
  • THRX-194556

    CAS:
    <p>THRX-194556 is an agonist of the 5-HT4 receptor. It is applicable in the study of gastrointestinal functional disorders and Alzheimer's disease.</p>
    Fórmula:C28H41N5O5S
    Cor e Forma:Solid
    Peso molecular:559.721
  • LB-102

    CAS:
    <p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>
    Fórmula:C18H29N3O4S
    Cor e Forma:Solid
    Peso molecular:383.51
  • MAO-B-IN-6


    <p>MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.</p>
    Cor e Forma:Solid
  • Beloxepin

    CAS:
    <p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>
    Fórmula:C19H21NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:295.38
  • MAO-B-IN-40

    CAS:
    <p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>
    Fórmula:C17H15N3O3
    Cor e Forma:Solid
    Peso molecular:309.319
  • MMB-4

    CAS:
    <p>MMB-4 is an oxime that can reactivate cholinesterases (cholinesterases) which have been inactivated due to exposure to organophosphates such as Sarin or Soman.</p>
    Fórmula:C13H14Br2N4O2
    Cor e Forma:Solid
    Peso molecular:418.084
  • 5-HT1A modulator 4

    CAS:
    <p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>
    Fórmula:C9H14N4
    Cor e Forma:Solid
    Peso molecular:178.234
  • AChE-IN-83

    CAS:
    <p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>
    Fórmula:C10H7ClN2O2S
    Cor e Forma:Solid
    Peso molecular:254.693
  • Pareptide monohydrochloride

    CAS:
    <p>Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).</p>
    Fórmula:C14H27ClN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:334.84
  • hAChE/Aβ1-42-IN-1

    CAS:
    <p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>
    Fórmula:C20H24N6O
    Cor e Forma:Solid
    Peso molecular:364.44
  • EF1502 free base

    CAS:
    <p>EF1502 is a potent and selective GABA transporter inhibitor.</p>
    Fórmula:C22H26N2O2S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:414.58
  • (+)-Sparteine sulfate pentahydrate


    <p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>
    Fórmula:C15H38N2O9S
    Cor e Forma:Solid
    Peso molecular:422.54
  • AChE/BACE1/GSK3β-IN-1


    <p>AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.</p>
    Fórmula:C26H27FN2O4
    Cor e Forma:Solid
    Peso molecular:450.5
  • nAChR antagonist 1

    CAS:
    <p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>
    Fórmula:C19H22N4O2
    Cor e Forma:Solid
    Peso molecular:338.4
  • Revexepride

    CAS:
    <p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>
    Fórmula:C21H32ClN3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:425.95