EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
Found 572 products of "EGFR"
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Tyrphostin A1
CAS:Formula:C11H8N2OPurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:184.20Methyl 2,5-Dihydroxycinnamate
CAS:Formula:C10H10O4Purity:>96.0%(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:194.19Genistein
CAS:Formula:C15H10O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:270.24Tyrphostin AG 835
CAS:Formula:C18H16N2O3Purity:>98.0%(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:308.34Erlotinib Hydrochloride
CAS:Formula:C22H23N3O4·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:429.90Tyrphostin AG 490
CAS:Formula:C17H14N2O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:294.31Pelitinib
CAS:Formula:C24H23ClFN5O2Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:467.93Tyrphostin A23
CAS:Formula:C10H6N2O2Purity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:186.17Tyrphostin AG 494
CAS:Formula:C16H12N2O3Purity:>98.0%(HPLC)(N)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:280.28Lapatinib
CAS:Formula:C29H26ClFN4O4SPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:581.06Curcumin (Natural)
CAS:Formula:C21H20O6Color and Shape:Light yellow to Brown powder to crystalMolecular weight:368.39PD 153035 Hydrochloride
CAS:Formula:C16H14BrN3O2·HClPurity:>97.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:396.67Gefitinib
CAS:Formula:C22H24ClFN4O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:446.91Curcumin (Synthetic)
CAS:Formula:C21H20O6Purity:>97.0%(T)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:368.39Butein
CAS:Formula:C15H12O5Purity:>98.0%(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:272.26Tyrphostin AG528
CAS:Formula:C18H14N2O3Purity:>97.0%(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:306.32Erlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.441-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
CAS:Formula:C25H23F3N4O2Purity:98%Color and Shape:SolidMolecular weight:468.4709AZ7550 hydrochloride
CAS:<p>AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formula:C27H32ClN7O2Purity:99.65%Color and Shape:SolidMolecular weight:522.04Intetumumab
CAS:<p>Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.</p>Purity:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.6 (kDa)Barecetamab
CAS:<p>Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.</p>Purity:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidEpertinib hydrochloride
CAS:<p>Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity.</p>Formula:C30H28Cl2FN5O3Purity:99.14%Color and Shape:SolidMolecular weight:596.48Pyrotinib dimaleate
CAS:<p>Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast cancer.Cost-effective and quality-assured.</p>Formula:C40H39ClN6O11Purity:97.27% - 99.52%Color and Shape:SolidMolecular weight:815.22Mutated EGFR-IN-1
CAS:<p>Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating</p>Formula:C25H31N7OPurity:98.91%Color and Shape:SolidMolecular weight:445.56Panitumumab
CAS:<p>Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).</p>Purity:95% - 98.1% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:147 kDaLCH-7749944
CAS:<p>LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.</p>Formula:C20H22N4O2Purity:99.48%Color and Shape:SolidMolecular weight:350.41Mevastatin
CAS:<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formula:C23H34O5Purity:99.12%Color and Shape:White-Yellowish To Yellow Powder Solid PowderMolecular weight:390.512-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-
CAS:Formula:C18H13BrN4OPurity:98%Color and Shape:SolidMolecular weight:381.2260Rilzabrutinib
CAS:<p>Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).</p>Formula:C36H40FN9O3Purity:98.28% - 99.76%Color and Shape:SolidMolecular weight:665.76Khellin
CAS:<p>Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.</p>Formula:C14H12O5Purity:99.89% - 99.95%Color and Shape:Light Yellow CrystallineMolecular weight:260.24Losatuxizumab
CAS:<p>Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody with potential anti-tumor activity for the study of advanced malignant solid tumors.</p>Purity:97.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.3% (SDS-PAGE); 95.1% (SEC-HPLC)Color and Shape:LiquidAV-412
CAS:<p>AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).</p>Formula:C41H44ClFN6O7S2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:851.41Lapatinib
CAS:<p>Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.</p>Formula:C29H26ClFN4O4SPurity:99.00% - 99.81%Color and Shape:PowderMolecular weight:581.06Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Formula:C11H8N2OPurity:98%Color and Shape:SolidMolecular weight:184.1940Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47Gancotamab
CAS:<p>Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.</p>Purity:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidMargetuximab
CAS:<p>Margetuximab (MGAH-22) is a second generation anti-HER2 monoclonal antibody with anti-tumor activity.</p>Purity:95.3% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.3% (SDS-PAGE); 99.3% (SEC-HPLC)Color and Shape:Liquid(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide
CAS:Formula:C18H16N2O3Purity:97%Color and Shape:SolidMolecular weight:308.3312Petosemtamab
CAS:<p>Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.97 kDaLapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46Gefitinib
CAS:<p>Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.</p>Formula:C22H24ClFN4O3Purity:99.92% - >99.99%Color and Shape:Light-Yellow Crystalline PowderMolecular weight:446.9Allitinib
CAS:<p>Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]</p>Formula:C24H18ClFN4O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:448.88O-Desmethyl gefitinib
CAS:<p>O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.</p>Formula:C21H22ClFN4O3Purity:97.17%Color and Shape:SolidMolecular weight:432.88Rociletinib
CAS:<p>Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic</p>Formula:C27H28F3N7O3Purity:98.52% - 99.25%Color and Shape:SolidMolecular weight:555.55Erlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4·HClPurity:99.78% - 99.85%Color and Shape:White Or Off-White PowderMolecular weight:429.9(2E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide
CAS:Formula:C18H24N2OSPurity:95%Color and Shape:SolidMolecular weight:316.4610
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