Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Formula:C16H14N2O3Purity:99.57%Color and Shape:SolidMolecular weight:282.29Rosmarinic acid
CAS:<p>Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.</p>Formula:C18H16O8Purity:98.88% - 99.73%Color and Shape:Brown Fine PowderMolecular weight:360.31SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Formula:C22H22O4Purity:99.73%Color and Shape:SolidMolecular weight:350.41Vanillyl Alcohol
CAS:<p>Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.</p>Formula:C8H10O3Purity:97.02% - 98.42%Color and Shape:Crystalline White To Off-White PowderMolecular weight:154.16Pyrogallol
CAS:<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Formula:C6H6O3Purity:99.88%Color and Shape:SoildMolecular weight:126.11Ixabepilone
CAS:<p>Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.</p>Formula:C27H42N2O5SPurity:98% - 99.50%Color and Shape:SolidMolecular weight:506.7NVP 231
CAS:<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Formula:C25H25N3O2SPurity:99.16% - ≥95%Color and Shape:SolidMolecular weight:431.55Taurolidine
CAS:<p>Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.</p>Formula:C7H16N4O4S2Purity:99.79% - 99.81%Color and Shape:SolidMolecular weight:284.36DC260126
CAS:<p>DC260126 is a small-molecule antagonist of FFA1 (GPR40)</p>Formula:C16H18FNO2SPurity:99.77%Color and Shape:SolidMolecular weight:307.38Rimiducid
CAS:<p>Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.</p>Formula:C78H98N4O20Purity:99.54%Color and Shape:SolidMolecular weight:1411.63Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Formula:C13H14N4OPurity:98.67%Color and Shape:SolidMolecular weight:242.28Eriocitrin
CAS:<p>Eriocitrin: an antioxidative flavonoid; reduces exercise-induced oxidative damage and lipids; fights fatty liver and inhibits carbonic anhydrase VA.</p>Formula:C27H32O15Purity:98.41% - 99.11%Color and Shape:SolidMolecular weight:596.53Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Formula:C39H43N3O11SPurity:≥98%Color and Shape:SolidMolecular weight:761.84Mirodenafil dihydrochloride
CAS:<p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>Formula:C26H39Cl2N5O5SPurity:99.64% - 99.78%Color and Shape:SolidMolecular weight:604.59Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Formula:C28H26N4O3Purity:99.24% - 99.82%Color and Shape:Off-White PowderMolecular weight:466.53Deoxypodophyllotoxin
CAS:<p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>Formula:C22H22O7Purity:99.65% - 99.84%Color and Shape:SolidMolecular weight:398.413-O-Methylgallic acid
CAS:<p>3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and</p>Formula:C8H8O5Purity:99.56%Color and Shape:SolidMolecular weight:184.15W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Formula:C16H22Cl2N2O2SPurity:99.63%Color and Shape:White Crystalline SolidMolecular weight:377.32ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Clobenpropit dihydrobromide
CAS:<p>Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)</p>Formula:C14H19Br2ClN4SPurity:99.86%Color and Shape:SolidMolecular weight:470.7SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Formula:C19H18BrN3OPurity:98.32% - 99.98%Color and Shape:SolidMolecular weight:384.27Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Formula:C21H19NO3SPurity:98.76% - 99.13%Color and Shape:SolidMolecular weight:365.45iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Formula:C23H26N2O2SPurity:98.32% - 98.47%Color and Shape:SolidMolecular weight:394.53Alvespimycin hydrochloride
CAS:<p>Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.</p>Formula:C32H48N4O8·HClPurity:99.94%Color and Shape:SolidMolecular weight:653.21Nivolumab
CAS:<p>Nivolumab is a monoclonal antibody, a humanized IgG4 antibody to PD-1. Nivolumab has antitumor activity. Cost-effective and quality-assured.</p>Purity:98% - 98%Color and Shape:LiquidMolecular weight:146 kDaPembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Purity:95% - 99.70%Color and Shape:LiquidMolecular weight:149 kDaTorin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Formula:C24H15F3N4OPurity:98.31% - 99.32%Color and Shape:SolidMolecular weight:432.4IITZ-01
CAS:<p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>Formula:C26H23FN8OPurity:99.31%Color and Shape:SolidMolecular weight:482.51Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Formula:C20H18O5Purity:98.92%Color and Shape:SolidMolecular weight:338.35NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Formula:C19H13NO4Purity:97.1% - 98.10%Color and Shape:SolidMolecular weight:319.31CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Formula:C18H13ClF6N2O3Purity:99.80%Color and Shape:SolidMolecular weight:454.75Solamargine
CAS:<p>Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.</p>Formula:C45H73NO15Purity:99.17% - 99.96%Color and Shape:SolidMolecular weight:868.06Demethylzeylasteral
CAS:<p>Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.</p>Formula:C29H36O6Purity:98.74% - 99.82%Color and Shape:SolidMolecular weight:480.59Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Formula:C50H71N13O12Purity:95% - >99.99%Color and Shape:SolidMolecular weight:1046.18PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Dexrazoxane
CAS:<p>Dexrazoxane (ICRF-187) is a mitosis-blocking anticancer drug, iron chelator, and anthracycline cardioprotectant.</p>Formula:C11H16N4O4Purity:99.88%Color and Shape:SolidMolecular weight:268.27Olsalazine
CAS:<p>Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.</p>Formula:C14H10N2O6Purity:99.31%Color and Shape:SolidMolecular weight:302.24SEC inhibitor KL-1
CAS:<p>KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.</p>Formula:C18H16ClNO4Purity:97.42%Color and Shape:SolidMolecular weight:345.78WYE-354
CAS:<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Formula:C24H29N7O5Purity:97.86% - 99.61%Color and Shape:SolidMolecular weight:495.53EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Formula:C19H15F2NOPurity:99.71%Color and Shape:SolidMolecular weight:311.33Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Formula:C11H11NO4SPurity:98.71%Color and Shape:SolidMolecular weight:253.27Simazine
CAS:<p>Simazine (Tafazine), a chlorotriazine herbicide/pesticide, may cause reproductive harm, endocrine disruption, and cancer.</p>Formula:C7H12ClN5Purity:99.82%Color and Shape:SolidMolecular weight:201.66McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Formula:C49H76N6O11Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:925.16Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formula:C15H22N2OPurity:99.89%Color and Shape:SolidMolecular weight:246.35
