Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6039 products of "Apoptosis"
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Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formula:C10H12ClN5O3Purity:99.58% - >99.99%Color and Shape:White Crystalline SolidMolecular weight:285.69TCS PrP Inhibitor 13
CAS:TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.Formula:C15H11N3O3Purity:99.7%Color and Shape:SolidMolecular weight:281.27Cyasterone
CAS:Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormula:C29H44O8Purity:99.32% - 99.70%Color and Shape:SolidMolecular weight:520.65Formosanin C
CAS:Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.Formula:C51H82O20Purity:98.98% - >99.99%Color and Shape:SolidMolecular weight:1015.18Trametinib (DMSO solvate)
CAS:Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)Formula:C28H29FIN5O5SPurity:99.71% - 99.92%Color and Shape:SolidMolecular weight:693.53Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26Triptolide
CAS:Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Formula:C20H24O6Purity:97.19% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:360.40Volasertib
CAS:Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.Formula:C34H50N8O3Purity:98% - 99.72%Color and Shape:SolidMolecular weight:618.81FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66Dihydrokaempferol
CAS:Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory activity.Formula:C15H12O6Purity:97.79% - 99.96%Color and Shape:SolidMolecular weight:288.25Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33CUDC-907 mesylate
CAS:CUDC-907 mesylate targets histone deacetylase & PI3K, developed by Curis for lymphomas, thyroid cancer, multiple myeloma, breast cancer.Formula:C24H28N8O7S2Color and Shape:SolidMolecular weight:604.66Selonsertib
CAS:Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.Formula:C24H24FN7OPurity:95.04% - 99.53%Color and Shape:SolidMolecular weight:445.49Calycosin
CAS:<p>Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).</p>Formula:C16H12O5Purity:99.91% - >99.99%Color and Shape:White PowderMolecular weight:284.26Prexasertib
CAS:Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!Formula:C18H19N7O2Purity:97.3% - 98.23%Color and Shape:SolidMolecular weight:365.39CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Formula:C21H25ClN2O2Purity:99.35% - 99.86%Color and Shape:SolidMolecular weight:372.88ZYN57939
CAS:ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.Formula:C28H27N7O2SPurity:99.81%Color and Shape:SolidMolecular weight:525.62SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Formula:C16H11ClF3N3O2SPurity:99.74%Color and Shape:SolidMolecular weight:401.79Calcium dobesilate
CAS:Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.Formula:C6H5O5SCa0Purity:98.39%Color and Shape:White Or Almost PowderMolecular weight:229.2CP-461 free base
CAS:CP-461 (OSI-461) is a pde2a / 5A inhibitor, which may be used in the treatment of renal cell carcinoma, prostate cancer, and Crohn's disease.Formula:C25H21FN2OColor and Shape:SolidMolecular weight:384.45CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formula:C24H17N3O4Purity:98.84%Color and Shape:SolidMolecular weight:411.41Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formula:C19H18O9Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:390.34LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:SolidMolecular weight:539.68CHS-828
CAS:CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formula:C19H22ClN5OPurity:98% - 99.9%Color and Shape:SolidMolecular weight:371.86MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Formula:C16H13F3N6OPurity:99.76%Color and Shape:SolidMolecular weight:362.31Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purity:98.76% - 99.92%Color and Shape:SolidMolecular weight:897.1Lenaldekar
CAS:Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.Formula:C18H14N4Purity:97.73%Color and Shape:SolidMolecular weight:286.33FR 180204
CAS:FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formula:C18H13N7Purity:98% - 99.74%Color and Shape:SolidMolecular weight:327.34MG 149
CAS:MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:351.4Navitoclax dihydrochloride
CAS:Navitoclax dihydrochloride is a synthetic Bcl-2 antagonist with potential cancer-fighting properties.Formula:C47H57Cl3F3N5O6S3Color and Shape:SolidMolecular weight:1047.54CAY10703
CAS:DCA blocks PDHK in mitochondria, shifting metabolism and aiding in cancer and diabetes treatment. CAY10703, a potent DCA form, targets leukemia cells.Formula:C12H18Cl6N4O3Color and Shape:SolidMolecular weight:479.01Phenoxyethanol
CAS:Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.Formula:C8H10O2Purity:99.47%Color and Shape:Clear To Practically Clear Colourless LiquidMolecular weight:138.16Fulvestrant
CAS:Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.Formula:C32H47F5O3SPurity:99.1% - >99.99%Color and Shape:White PowderMolecular weight:606.77Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formula:C15H17ClFNO4SPurity:99.31% - >99.99%Color and Shape:SolidMolecular weight:361.82Quinacrine acetate
CAS:Quinacrine acetate is a histamine N-methyltransferase inhibitor.Formula:C25H34ClN3O3Color and Shape:SolidMolecular weight:460.01Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formula:C24H22O6Purity:98.40% - 98.59%Color and Shape:SolidMolecular weight:406.43ICCB280
CAS:<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Formula:C23H18N2O4Purity:98.04%Color and Shape:SolidMolecular weight:386.4Thalidomide-O-amido-C6-NH2 TFA
CAS:Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-basedFormula:C46H53F6N8O16Purity:95.16%Color and Shape:SolidMolecular weight:1087.95Briciclib
CAS:Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formula:C19H23O10PSPurity:98% - 99.84%Color and Shape:SolidMolecular weight:474.42Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formula:C15H10O7Purity:96.29% - 98.05%Color and Shape:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Molecular weight:302.24FB23-2
CAS:FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).Formula:C18H15Cl2N3O3Purity:97.29% - ≥95%Color and Shape:SolidMolecular weight:392.24BAY 61-3606 HCl
CAS:BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formula:C20H19ClN6O3Color and Shape:SolidMolecular weight:426.86Sodium Demethylcantharidate
CAS:Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.Formula:C8H9O5·NaPurity:99.66% - ≥98%Color and Shape:SolidMolecular weight:208.14Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formula:C15H16ClN3O5Purity:98.56%Color and Shape:SolidMolecular weight:353.76Ricolinostat
CAS:<p>Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.</p>Formula:C24H27N5O3Purity:97.17% - 99.76%Color and Shape:SolidMolecular weight:433.5
