Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(27 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6063 products of "Apoptosis"
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PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purity:99.40%Color and Shape:SolidMolecular weight:557.56Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurity:98% - 99.91%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:301.32Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:266.29Rhapontin
CAS:Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.Formula:C21H24O9Purity:99% - 99.91%Color and Shape:Light YellowMolecular weight:420.41Perillyl alcohol
CAS:Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.Formula:C10H16OPurity:97.36%Color and Shape:SolidMolecular weight:152.23Euscaphic acid
CAS:Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.Formula:C30H48O5Purity:98.93%Color and Shape:SolidMolecular weight:488.7Licochalcone B
CAS:Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.Formula:C16H14O5Purity:99.33% - 99.9%Color and Shape:SolidMolecular weight:286.28Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Formula:C30H41FN4O12Purity:96.19% - 99.69%Color and Shape:SolidMolecular weight:668.66Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purity:99.53% - 99.79%Color and Shape:SolidMolecular weight:553.59Pitstop 2
CAS:<p>Pitstop2 is an amphipathic protein-bound inhibitor of the clathrin terminal domain. Pitstop2 has antitumor activity. Cost-effective, quality assurance.</p>Formula:C20H13BrN2O3S2Purity:99.54%Color and Shape:SolidMolecular weight:473.36ZM 336372
CAS:ZM 336372 is a potent and selective c-Raf inhibitor.Formula:C23H23N3O3Purity:97.24% - 97.51%Color and Shape:SolidMolecular weight:389.45Notoginsenoside R1
CAS:Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.Formula:C47H80O18Purity:99.69% - 99.91%Color and Shape:SolidMolecular weight:933.13Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formula:C20H34OPurity:99.17% - ≥98%Color and Shape:SolidMolecular weight:290.48Avelumab
CAS:Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.Purity:95% - 97.17% (SDS-PAGE)Color and Shape:LiquidMolecular weight:143.8 kDaEvofosfamide
CAS:Evofosfamide (TH-302) is a hypoxia-activated prodrug that releases Br-IPM in tumors to cause DNA damage and potentially induce apoptosis.Formula:C9H16Br2N5O4PPurity:98.74% - 99.75%Color and Shape:SolidMolecular weight:449.04Buparlisib
CAS:Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).Formula:C18H21F3N6O2Purity:95.32% - 98.45%Color and Shape:SolidMolecular weight:410.39NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23SSE15206
CAS:SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance.Formula:C19H21N3O3SPurity:98.81%Color and Shape:SolidMolecular weight:371.45Amsilarotene
CAS:Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.Formula:C20H27NO3Si2Purity:98.05%Color and Shape:SolidMolecular weight:385.6Ac-DEVD-CHO acetate
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.Formula:C22H34N4O13Purity:98.54%Color and Shape:SolidMolecular weight:562.52Estramustine phosphate sodium
CAS:Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.Formula:C23H30Cl2NNa2O6PPurity:96.44% - 99.54%Color and Shape:SolidMolecular weight:564.35Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Formula:C19H20N4O·C7H8O3SPurity:99.34% - 99.87%Color and Shape:SolidMolecular weight:492.59Rigosertib sodium
CAS:Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.Formula:C21H24NNaO8SPurity:98% - 99.37%Color and Shape:SolidMolecular weight:473.47Tenovin-1
CAS:Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.Formula:C20H23N3O2SPurity:99.33%Color and Shape:SolidMolecular weight:369.48Cyclovirobuxine D
CAS:Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formula:C26H46N2OPurity:97.78% - 98%Color and Shape:SolidMolecular weight:402.66IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Formula:C21H21BrN4O5Purity:99.13%Color and Shape:SolidMolecular weight:489.32Dantrolene
CAS:Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.Formula:C14H10N4O5Purity:99.97%Color and Shape:Crystals From Aq DimethylformamideMolecular weight:314.25Tartrazine
CAS:Tartrazine, a food colorant with potential health risks, may be genotoxic and carcinogenic with long-term use.Formula:C16H9N4Na3O9S2Purity:98.77% - 98.82%Color and Shape:Yellow Solid PowderMolecular weight:534.36Iberdomide
CAS:Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).Formula:C25H27N3O5Purity:97.01%Color and Shape:SolidMolecular weight:449.5D-Pantothenic acid hemicalcium salt
CAS:D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice.Formula:C9H17NO5CaPurity:98% - 99.89%Color and Shape:White Crystalline PowderMolecular weight:239.28Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Formula:C21H19ClN4O2Purity:93.468% - 99.31%Color and Shape:SolidMolecular weight:394.85AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Formula:C20H20N6OPurity:99.52%Color and Shape:SolidMolecular weight:360.41Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Formula:C20H21N3O2·HClPurity:97.24% - 99.15%Color and Shape:SolidMolecular weight:371.86Ganoderenic acid D
CAS:Ganoderenic acid D, extracted from Ganoderma lucidum, triggers apoptosis and halts cancer cell growth.Formula:C30H40O7Purity:99.05%Color and Shape:SolidMolecular weight:512.63Niraparib hydrochloride
CAS:Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85Aspirin calcium
CAS:Aspirin calcium: used for mild/moderate pain; anti-inflammatory, antipyretic, inhibits cyclooxygenase, prostaglandin synthesis; prevents thrombosis.Formula:C18H14CaO8Color and Shape:SolidMolecular weight:398.38SHP099
CAS:SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cellsFormula:C16H19Cl2N5Purity:98.73% - 99.4%Color and Shape:SolidMolecular weight:352.26Avotaciclib trihydrochloride
CAS:Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.Formula:C13H14Cl3N7OPurity:99%Color and Shape:SolidMolecular weight:390.65Propylparaben
CAS:Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agentFormula:C10H12O3Purity:99.84%Color and Shape:White Solid CrystallineMolecular weight:180.20Navitoclax
CAS:View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.Formula:C47H55ClF3N5O6S3Purity:95.82% - >99.99%Color and Shape:Pale Yellow SolidMolecular weight:974.61Diethylnorspermine HBr
CAS:DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.Formula:C13H36Br4N4Color and Shape:SolidMolecular weight:568.075Tivantinib
CAS:Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.Formula:C23H19N3O2Purity:98% - 99.41%Color and Shape:SolidMolecular weight:369.42AKN-028 trifluoroacetate
CAS:AKN-028 trifluoroacetate causes cell cycle arrest and lowers Myc genes and tyrosine kinase activity in AML.Formula:C19H15F3N6O2Color and Shape:SolidMolecular weight:416.36Metformin glycinate
CAS:Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Formula:C6H16N6O2Color and Shape:SolidMolecular weight:204.23Maprotiline
CAS:Maprotiline blocks norepinephrine uptake, has antidepressant properties, and fights cancer by inducing apoptosis and inhibiting ERK and CRABP1.Formula:C20H23NColor and Shape:SolidMolecular weight:277.4Dihydrokaempferol
CAS:Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory activity.Formula:C15H12O6Purity:97.79% - 99.96%Color and Shape:SolidMolecular weight:288.25Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33
