Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6068 products of "Apoptosis"
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Fimepinostat
CAS:Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.Formula:C23H24N8O4SPurity:98.27% - 99.87%Color and Shape:SolidMolecular weight:508.55Ref: TM-T2078
2mg47.00€5mg70.00€10mg97.00€25mg175.00€50mg311.00€100mg512.00€500mg1,093.00€1mL*10mM (DMSO)79.00€YUM70
CAS:YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.Formula:C21H19ClN2O4Purity:97.25%Color and Shape:SolidMolecular weight:398.84Ref: TM-T8901
1mg48.00€5mg96.00€10mg135.00€25mg264.00€50mg389.00€100mg553.00€200mg750.00€1mL*10mM (DMSO)96.00€LYN-1604 hydrochloride
CAS:LYN-1604 HCl activates ULK1 (EC50: 18.94 nM); key for studying TNBC.Formula:C33H44Cl3N3O2Color and Shape:SolidMolecular weight:621.08BIX01294 (hydrochloride hydrate)
CAS:BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.Formula:C28H43Cl3N6O3Color and Shape:SolidMolecular weight:618.04PF-3758309 dihydrochloride
PF-3758309 dihydrochloride is a potent PAK4 inhibitor (Kd = 2.7 nM, Ki = 18.7 nM), oral, ATP-competitive; blocks cell growth, induces apoptosis.Formula:C25H32Cl2N8OSColor and Shape:SolidMolecular weight:563.55SKI V
CAS:<p>SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),</p>Formula:C15H10O4Purity:98.78%Color and Shape:SolidMolecular weight:254.24UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Ref: TM-T8662
1mgTo inquire2mg49.00€5mg80.00€10mg111.00€25mg160.00€50mg202.00€100mg283.00€200mg419.00€1mL*10mM (DMSO)89.00€Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1030.29Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4Ref: TM-T4518
1mg96.00€5mg227.00€10mg329.00€25mg548.00€50mg782.00€100mg1,035.00€1mL*10mM (DMSO)To inquireTeneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formula:C22H30N6OSBrHPurity:97.83% - 99.92%Color and Shape:SolidMolecular weight:628.869-Methoxycamptothecin
CAS:9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.Formula:C21H18N2O5Purity:98.49% - 99.56%Color and Shape:SolidMolecular weight:378.38Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Formula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.54E1rcat
CAS:4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formula:C28H18N2O6Purity:99.47%Color and Shape:SolidMolecular weight:478.454-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurity:97.18%Color and Shape:SolidMolecular weight:313.42Ref: TM-T8794
2mg37.00€5mg56.00€10mg90.00€25mg164.00€50mg259.00€100mg424.00€200mg600.00€1mL*10mM (DMSO)62.00€Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:588.27UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Formula:C32H43N5O2Purity:98% - 99.04%Color and Shape:SolidMolecular weight:529.72Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Formula:C22H24N2O7SPurity:98.13% - 99.95%Color and Shape:SolidMolecular weight:460.50RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purity:98.49% - 99.55%Color and Shape:SolidMolecular weight:292.37Ref: TM-T1798
1mg35.00€5mg66.00€10mg96.00€25mg187.00€50mg279.00€100mg420.00€200mg607.00€1mL*10mM (DMSO)89.00€Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Formula:C9H10O5Purity:98.4% - 99.74%Color and Shape:SolidMolecular weight:198.17TPCA-1
CAS:TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinasesFormula:C12H10FN3O2SPurity:95.03% - 97.86%Color and Shape:SolidMolecular weight:279.29Kumatakenin
CAS:Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.Formula:C17H14O6Purity:97.44% - 98.41%Color and Shape:SolidMolecular weight:314.29BG45
CAS:BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.Formula:C11H10N4OPurity:99.77%Color and Shape:SolidMolecular weight:214.22Epoxomicin
CAS:Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.Formula:C28H50N4O7Purity:98.65% - 98.86%Color and Shape:White To Off-White SolidMolecular weight:554.72Ref: TM-T6830
1mg125.00€5mg311.00€10mg502.00€25mg817.00€50mg1,130.00€100mg1,501.00€500mg3,022.00€1mL*10mM (DMSO)375.00€LDN-57444
CAS:LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .Formula:C17H11Cl3N2O3Purity:97.8% - 99.87%Color and Shape:SolidMolecular weight:397.64K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:SolidMolecular weight:719.91Eltrombopag
CAS:Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the plateletFormula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47Brassinolide
CAS:Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.Formula:C28H48O6Purity:98% - 99.189%Color and Shape:Off-White SolidMolecular weight:480.68DD1
CAS:DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.Formula:C16H14N2O3Purity:99.57%Color and Shape:SolidMolecular weight:282.29Ref: TM-T8978
1mg74.00€5mg138.00€10mg226.00€25mg356.00€50mg492.00€100mg665.00€200mg898.00€1mL*10mM (DMSO)145.00€SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Ref: TM-T8922
1mg46.00€5mg80.00€10mg116.00€25mg227.00€50mg359.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)105.00€Millepachine
CAS:Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.Formula:C22H22O4Purity:99.73%Color and Shape:SolidMolecular weight:350.41Ref: TM-T38815
1mg55.00€5mg116.00€10mg156.00€25mg259.00€50mg378.00€100mg567.00€200mg748.00€1mL*10mM (DMSO)134.00€Vanillyl Alcohol
CAS:Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.Formula:C8H10O3Purity:97.02% - 98.42%Color and Shape:Crystalline White To Off-White PowderMolecular weight:154.16Ixabepilone
CAS:Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.Formula:C27H42N2O5SPurity:98% - 99.50%Color and Shape:SolidMolecular weight:506.7Ref: TM-T6864
1mg57.00€2mg93.00€5mg188.00€10mg344.00€25mg560.00€50mg815.00€100mg1,093.00€200mg1,473.00€1mL*10mM (DMSO)217.00€CCCP
CAS:CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.Formula:C9H5ClN4Purity:97.15% - 99.64%Color and Shape:Yellow To Orange PowderMolecular weight:204.62Deoxypodophyllotoxin
CAS:Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Formula:C22H22O7Purity:99.65% - 99.84%Color and Shape:SolidMolecular weight:398.413-O-Methylgallic acid
CAS:3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins andFormula:C8H8O5Purity:99.56%Color and Shape:SolidMolecular weight:184.15Clobenpropit dihydrobromide
CAS:Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)Formula:C14H19Br2ClN4SPurity:99.86%Color and Shape:SolidMolecular weight:470.7SCR130
CAS:SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3Flavokawain A
CAS:NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.Formula:C18H18O5Purity:97.1% - 99.72%Color and Shape:SolidMolecular weight:314.332EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formula:C21H18F3N5OPurity:98.3% - 99.76%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5168
1mg82.00€5mg159.00€10mg259.00€25mg520.00€50mg740.00€100mg1,008.00€500mg2,015.00€1mL*10mM (DMSO)168.00€HJC0152 hydrochloride
CAS:HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.Formula:C15H14Cl3N3O4Purity:99.01% - 99.06%Color and Shape:SolidMolecular weight:406.64NQDI-1
CAS:NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).Formula:C19H13NO4Purity:97.1% - 98.10%Color and Shape:SolidMolecular weight:319.31Ref: TM-T3101
5mg48.00€10mg73.00€25mg144.00€50mg259.00€100mg393.00€200mg560.00€500mg893.00€1mL*10mM (DMSO)52.00€Solamargine
CAS:Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.Formula:C45H73NO15Purity:99.17% - 99.96%Color and Shape:SolidMolecular weight:868.06Ref: TM-T4034
1mg59.00€2mg82.00€5mg115.00€10mg168.00€25mg305.00€50mg459.00€100mg692.00€200mg933.00€1mL*10mM (DMSO)166.00€PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22Ref: TM-T6932
1mg39.00€2mg49.00€5mg66.00€10mg89.00€25mg155.00€50mg222.00€100mg310.00€1mL*10mM (DMSO)56.00€EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formula:C19H15F2NOPurity:99.71%Color and Shape:SolidMolecular weight:311.33Ref: TM-T27242
1g1,510.00€1mg40.00€5mg85.00€10mg133.00€25mg235.00€50mg354.00€100mg533.00€500mg1,130.00€1mL*10mM (DMSO)93.00€Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formula:C11H11NO4SPurity:98.71%Color and Shape:SolidMolecular weight:253.27Ref: TM-T19692
1mg104.00€5mg235.00€10mg364.00€25mg582.00€50mg817.00€100mg1,121.00€1mL*10mM (DMSO)216.00€CDPPB
CAS:<p>CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).</p>Formula:C23H16N4OPurity:99.16%Color and Shape:SolidMolecular weight:364.4Iproniazid
CAS:Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.Formula:C9H13N3OPurity:98%Color and Shape:SolidMolecular weight:179.22NUN82647
CAS:NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.Formula:C15H13N3O2SPurity:98.91%Color and Shape:SolidMolecular weight:299.35Ref: TM-T8331
1mg47.00€5mg87.00€10mg140.00€25mg250.00€50mg376.00€100mg550.00€200mg743.00€1mL*10mM (DMSO)96.00€
