Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(6 products)
- Caspase(151 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(106 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(59 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6041 products of "Apoptosis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Mollugin
CAS:Controlled ProductApplications Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.
References Zhang, L. et al.: Biochem. Biophys. Res. Comm., 450, 247 (2014); Idhayadhulla, A. et al.: Bioorg. Chem., 52, 77 (2014);Formula:C17H16O4Color and Shape:NeatMolecular weight:284.31(R)-Irofulven
CAS:Controlled ProductApplications Semi-synrhetic antitumor agent derived from Illudin S. Inhibits DNA synthesis and induces apoptosis in tumor cells. Antineoplastic.
References Woynarowski, J.M., et al.: Biochem. Pharmacol., 54, 1181 (1997), Alexandre, J., et al.: Clin. Cancer Res., 10, 3377 (2004), Senzer, N., et al.: Am. J. Clin. Oncol., 28, 36 (2005),Formula:C15H18O3Color and Shape:NeatMolecular weight:246.31Camptothecin
CAS:Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.Formula:C20H16N2O4Purity:99.52% - 99.88%Color and Shape:Solid PowderMolecular weight:348.35SAR405838
CAS:MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.Formula:C29H34Cl2FN3O3Purity:98.63%Color and Shape:SolidMolecular weight:562.5Ref: TM-T6585
1mg49.00€2mg90.00€5mg133.00€10mg213.00€25mg419.00€50mg617.00€100mg879.00€500mg1,776.00€Dibenz[a,h]anthracene
CAS:Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell
Formula:C22H14Purity:99.97%Color and Shape:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Molecular weight:278.35L-Cystathionine
CAS:L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.
Formula:C7H14N2O4SPurity:96.43% - >99.99%Color and Shape:SolidMolecular weight:222.26NPB
CAS:NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)Formula:C29H31Cl2N3O2Purity:99.93%Color and Shape:SolidMolecular weight:524.48Ref: TM-T12249
1mg52.00€5mg105.00€10mg170.00€25mg279.00€50mg386.00€100mg510.00€200mg700.00€1mL*10mM (DMSO)117.00€Riviciclib hydrochloride
CAS:Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.Formula:C21H20ClNO5·HClPurity:99.51%Color and Shape:SolidMolecular weight:438.3SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formula:C28H30ClN5O4SPurity:98.62% - 99.53%Color and Shape:Orange PowderMolecular weight:568.09Ref: TM-T6154
1mg44.00€2mg56.00€5mg92.00€10mg142.00€25mg268.00€50mg442.00€100mg652.00€1mL*10mM (DMSO)142.00€Flurochloridone
CAS:Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.Formula:C12H10Cl2F3NOPurity:99.86%Color and Shape:SolidMolecular weight:312.12Cot inhibitor-2
CAS:Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.Formula:C26H25Cl2FN8Purity:99.85%Color and Shape:SolidMolecular weight:539.43Ref: TM-T10866
1mg72.00€5mg158.00€10mg243.00€25mg512.00€50mg753.00€100mg1,074.00€200mg1,444.00€1mL*10mM (DMSO)180.00€C1A
CAS:C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.Formula:C22H25Cl2N3O4SColor and Shape:SolidMolecular weight:498.42Anticancer agent 67
CAS:Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.Formula:C26H24F2N6O2S2Color and Shape:SolidMolecular weight:554.63SMBA2
CAS:SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.Formula:C8H16N4Purity:98%Color and Shape:SolidMolecular weight:168.24RC-33 HCl
CAS:RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.Formula:C21H28ClNPurity:98%Color and Shape:SolidMolecular weight:329.91Jolkinolide B
CAS:Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.
Formula:C20H26O4Purity:99.39% - 99.7%Color and Shape:SolidMolecular weight:330.42WK-298
CAS:WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.Formula:C35H38Cl2N6OPurity:98%Color and Shape:SolidMolecular weight:629.62NVS-CECR2-1
CAS:NVS-CECR2-1 is a CECR2 inhibitor with anti-tumor activity that inhibits chromatin binding of the CECR2 BRD.Formula:C27H37N5O2SPurity:98.68%Color and Shape:SolidMolecular weight:495.68IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purity:98%Color and Shape:SolidMolecular weight:179.26MI-389
CAS:MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.Formula:C35H35FN6O6Purity:98.12%Color and Shape:SolidMolecular weight:654.69Ref: TM-T33380
1mg88.00€5mg204.00€10mg304.00€25mg476.00€50mg811.00€100mg1,401.00€1mL*10mM (DMSO)276.00€A 410099.1
CAS:A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formula:C27H41ClN4O3Purity:99.30%Color and Shape:SolidMolecular weight:505.1Quinidine Monosulfate
CAS:Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.Formula:C40H50N4O8SColor and Shape:SolidMolecular weight:746.92APPA
CAS:APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition ofFormula:C14H13NO3Purity:98%Color and Shape:SolidMolecular weight:243.265HPP-33
CAS:5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.Formula:C20H21NO3Color and Shape:SolidMolecular weight:323.39Mcl-1 inhibitor 10
CAS:Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.Formula:C21H15F3O4Color and Shape:SolidMolecular weight:388.34Anti-osteoporosis agent-1
CAS:Anti-osteoporosis agent-1 (comp 4aa) is an effective RPA (replication protein A) inhibitor, demonstrating potency with an IC50 value of 18 μM [1].Formula:C20H19ClN2O2Color and Shape:SolidMolecular weight:354.83Ramentaceone
CAS:Ramentaceone is an antineoplastic.Formula:C11H8O3Purity:98%Color and Shape:SolidMolecular weight:188.18MIR96-IN-1
CAS:MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.Formula:C33H48N8O2Color and Shape:SolidMolecular weight:588.79STK17A/B-IN-1
CAS:STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.Formula:C26H27N7OColor and Shape:SolidMolecular weight:453.54B-Raf IN 9
CAS:B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).Formula:C23H20N4OSColor and Shape:SolidMolecular weight:400.5PI3Kα-IN-7
CAS:PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.
Formula:C17H22N8O2SColor and Shape:SolidMolecular weight:402.47VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.Formula:C26H20Cl2F3N5O3S2Color and Shape:SolidMolecular weight:642.5Metaproterenol
CAS:Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).Formula:C11H17NO3Purity:98%Color and Shape:SolidMolecular weight:211.26Apoptotic agent-1
CAS:Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.Formula:C12H6ClN5O2SColor and Shape:SolidMolecular weight:319.73LG190178
CAS:LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.
Formula:C28H42O5Color and Shape:SolidMolecular weight:458.63Theophylline sodium glycinate
CAS:Theophylline sodium glycinate inhibits PDE3, treats asthma/COPD, blocks adenosine receptors, activates HDAC, reduces inflammation and induces apoptosis.Formula:C9H12N5NaO4Color and Shape:SolidMolecular weight:277.216MMP-9-IN-3
CAS:MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.Formula:C29H25N3O4Color and Shape:SolidMolecular weight:479.53ZMF-10
CAS:ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.Formula:C19H17F6N7OColor and Shape:SolidMolecular weight:473.38αβ-Tubulin-IN-1
CAS:αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.Formula:C25H19N3O3Color and Shape:SolidMolecular weight:409.44PDPOB
CAS:PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.Formula:C15H20O5Color and Shape:SolidMolecular weight:280.32GLS1 Inhibitor-4
CAS:GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.Formula:C29H27F3N10O2S2Purity:98%Color and Shape:SolidMolecular weight:668.72EGFR-IN-88
CAS:EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormula:C22H18Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:473.37MR2938
CAS:MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Formula:C21H24N4O3Color and Shape:SolidMolecular weight:380.44BMS-566394
CAS:BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formula:C22H21F3N4O4Color and Shape:SolidMolecular weight:462.42p53 Activator 2
CAS:p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.Formula:C20H21N5O2Color and Shape:SolidMolecular weight:363.41(S)-PERK-IN-5
CAS:(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).Formula:C25H26F2N4O3Color and Shape:SolidMolecular weight:468.5Se-Methylselenocysteine hydrochloride
CAS:Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54Anticancer agent 83
CAS:Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.Formula:C20H19N5OSColor and Shape:SolidMolecular weight:377.46
![Dibenz[a,h]anthracene](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT31425.webp&w=3840&q=75)
