Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(127 products)
- FOXO1(3 products)
- IAP(65 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(24 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(91 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5622 products of "Apoptosis"
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Merck-22-6
CAS:<p>Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.</p>Formula:C40H43N7O2Color and Shape:SolidMolecular weight:653.82BP-1-108
CAS:<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Formula:C32H38N2O6SColor and Shape:SolidMolecular weight:578.72Glucocorticoid receptor modulator 1
CAS:<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Formula:C24H23ClN2O4SPurity:99.79%Color and Shape:SolidMolecular weight:470.97SMI-6860766
CAS:<p>SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.</p>Formula:C15H11BrClNOPurity:98%Color and Shape:SolidMolecular weight:336.612,3-DCPE
CAS:Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).Formula:C11H15Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:264.15WJ35435
CAS:<p>WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.</p>Formula:C20H21N3O3Purity:98%Color and Shape:SolidMolecular weight:351.4(1S,2S)-Bortezomib
CAS:(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.Formula:C19H25BN4O4Purity:99.6%Color and Shape:SolidMolecular weight:384.24BPTQ
CAS:<p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>Formula:C17H16N4SPurity:98%Color and Shape:SolidMolecular weight:308.4TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formula:C17H17NOPurity:99.76%Color and Shape:SolidMolecular weight:251.32Anticancer agent 57
CAS:<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Formula:C20H21Cl2NO2Color and Shape:SolidMolecular weight:378.29CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Formula:C35H53N7O7Color and Shape:SolidMolecular weight:683.84HX 630
CAS:<p>RXR agonist</p>Formula:C28H27NO2SPurity:98%Color and Shape:SolidMolecular weight:441.58VEGFR-2-IN-19
CAS:<p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>Formula:C21H19N3O2Color and Shape:SolidMolecular weight:345.39Imofinostat
CAS:Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells.Formula:C17H16N2O4SColor and Shape:SolidMolecular weight:344.38MG-115
CAS:<p>MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.</p>Formula:C25H39N3O5Purity:97.12%Color and Shape:White PowderMolecular weight:461.59RET-IN-6
CAS:<p>RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).</p>Formula:C30H29N7Color and Shape:SolidMolecular weight:487.6BLM-IN-1
CAS:BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.Formula:C28H35FN4OColor and Shape:SolidMolecular weight:462.6SKF1
CAS:SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.Formula:C23H37ClN2O2Purity:98%Color and Shape:SolidMolecular weight:409.01BCL6-IN-8c
CAS:BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbentFormula:C20H20ClN3O5Color and Shape:SolidMolecular weight:417.84eIF4A3-IN-2
CAS:eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formula:C25H19Br2ClN4O2Purity:98%Color and Shape:SolidMolecular weight:602.715HPP-33
CAS:5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.Formula:C20H21NO3Color and Shape:SolidMolecular weight:323.39Ivaltinostat
CAS:<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Formula:C24H33N3O4Purity:98%Color and Shape:SolidMolecular weight:427.54Tubulin polymerization-IN-24
CAS:<p>HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.</p>Formula:C22H16O3Color and Shape:SolidMolecular weight:328.36HBV-IN-23
CAS:<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Formula:C25H27N3O3SColor and Shape:SolidMolecular weight:449.57Nec-3a
CAS:<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formula:C21H18F4N2O4Color and Shape:SolidMolecular weight:438.37RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Formula:C32H33FN6O4Color and Shape:SolidMolecular weight:584.64TP-472
CAS:<p>TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).</p>Formula:C20H19N3O2Purity:98%Color and Shape:SolidMolecular weight:333.38GW7845
CAS:<p>GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.</p>Formula:C29H28N2O6Purity:98%Color and Shape:SolidMolecular weight:500.54Metoprolol fumarate
CAS:<p>Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.</p>Formula:C34H54N2O10Color and Shape:SolidMolecular weight:650.8BMH-7
CAS:<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Formula:C20H21N5OPurity:99.71%Color and Shape:SolidMolecular weight:347.41Tubulin polymerization-IN-13
CAS:<p>Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.</p>Formula:C20H21NO6Color and Shape:SolidMolecular weight:371.38Topoisomerase I inhibitor 3
CAS:<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Formula:C18H14FNO3Color and Shape:SolidMolecular weight:311.31Shield-2
CAS:<p>Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.</p>Formula:C35H51N3O7Purity:98%Color and Shape:SolidMolecular weight:625.8Anticancer agent 77
CAS:<p>Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.</p>Formula:C25H30BrN7Color and Shape:SolidMolecular weight:508.46GKK1032B
CAS:<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Formula:C32H39NO4Color and Shape:SolidMolecular weight:501.66AFG206
CAS:AFG206 is the novel first-generation type II" FLT3 inhibitor."Formula:C20H19N3O2Color and Shape:SolidMolecular weight:333.38D-Cl-amidine
CAS:<p>D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.</p>Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78AG-024322
CAS:AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.Formula:C23H20F2N6Purity:98.53%Color and Shape:SolidMolecular weight:418.44OXPHOS-IN-1
CAS:<p>OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).</p>Formula:C19H29N3O6S2Color and Shape:SolidMolecular weight:459.58ZDLD13
CAS:<p>ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.</p>Formula:C18H14N4OColor and Shape:SolidMolecular weight:302.33EGFR-IN-52
CAS:<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44SPRC
CAS:<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formula:C6H9NO2SPurity:98%Color and Shape:SolidMolecular weight:159.21DRAK2-IN-1
CAS:<p>Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).</p>Formula:C21H20N4O3Color and Shape:SolidMolecular weight:376.41Autophagy-IN-2
CAS:<p>Autophagy-IN-2 (7h) blocks autophagic flux, triggers cancer cell death, aids in triple-negative breast cancer study.</p>Formula:C17H19N5OColor and Shape:SolidMolecular weight:309.37LSD1-IN-14
CAS:<p>LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.</p>Formula:C21H24FN5Color and Shape:SolidMolecular weight:365.45BJE6-106
CAS:<p>BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).</p>Formula:C26H23NO2Color and Shape:SolidMolecular weight:381.47YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formula:C24H24N6OColor and Shape:SolidMolecular weight:412.49Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47Anticancer agent 63
CAS:<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Formula:C17H24F3NOSeColor and Shape:SolidMolecular weight:394.33CSRM617
CAS:<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Formula:C10H13N3O5Purity:98%Color and Shape:SolidMolecular weight:255.23
