Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
Show 10 more subcategories
Found 3480 products of "Cell Cycle/Checkpoint"
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WEE1-IN-3
CAS:<p>WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.</p>Formula:C28H31N7O2Purity:98.33%Color and Shape:SolidMolecular weight:497.59ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Formula:C28H24Cl2FN5O2Purity:97.01% - 98.38%Color and Shape:SolidMolecular weight:552.43Bredinin aglycone
CAS:<p>Bredinin aglycone (SM-108) is a purine nucleotide analog.</p>Formula:C4H5N3O2Purity:99.06%Color and Shape:SolidMolecular weight:127.1Palbociclib monohydrochloride
CAS:<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>Formula:C24H29N7O2·HClPurity:99.73% - >99.99%Color and Shape:SolidMolecular weight:483.99Nolatrexed
CAS:<p>Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.</p>Formula:C14H12N4OSPurity:97.53%Color and Shape:SolidMolecular weight:284.34Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
<p>Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation</p>Formula:C76H121N19O25SPurity:98.96%Color and Shape:SolidMolecular weight:1732.95PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formula:C17H13Br2N5OS·HBrPurity:99.91%Color and Shape:SolidMolecular weight:576.1CVT-313
CAS:<p>CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.</p>Formula:C20H28N6O3Purity:97.46% - 97.97%Color and Shape:SolidMolecular weight:400.47YKL-5-124
CAS:<p>YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays</p>Formula:C28H33N7O3Purity:99.36%Color and Shape:SolidMolecular weight:515.61GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45Raltitrexed
CAS:<p>Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.</p>Formula:C21H22N4O6SPurity:98.99% - 99.29%Color and Shape:Yellow Crystalline PowderMolecular weight:458.49AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.58MKC3946
CAS:<p>MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.</p>Formula:C21H20N2O3SPurity:99.65%Color and Shape:SolidMolecular weight:380.462′-O-Methylcytidine
CAS:<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Formula:C10H15N3O5Purity:99.72%Color and Shape:SolidMolecular weight:257.24Palbociclib Isethionate
CAS:<p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>Formula:C24H29N7O2·C2H6O4SPurity:99.01% - 99.27%Color and Shape:SolidMolecular weight:573.66Arginine-glycine-aspartic acid
CAS:<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34ML264
CAS:<p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>Formula:C17H21ClN2O4SPurity:99.33% - 99.45%Color and Shape:SolidMolecular weight:384.88CCT241736
CAS:<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.3710058-F4
CAS:<p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.</p>Formula:C12H11NOS2Purity:98% - 99.87%Color and Shape:SolidMolecular weight:249.35LDN-192960 hydrochloride
CAS:<p>LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.</p>Formula:C18H22Cl2N2O2SPurity:98%Color and Shape:SolidMolecular weight:401.35Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formula:C10H9AgN4O2SPurity:99.04% - 99.58%Color and Shape:SolidMolecular weight:357.14Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4Ara-G
CAS:<p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>Formula:C10H13N5O5Purity:98.74%Color and Shape:Slightly Off White To White PowderMolecular weight:283.24Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55Didox
CAS:<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Formula:C7H7NO4Purity:99.83%Color and Shape:SolidMolecular weight:169.13T56-LIMKi
CAS:<p>T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.</p>Formula:C19H14F3N3O3Purity:98.39% - 99.57%Color and Shape:SolidMolecular weight:389.33Mycro 3
CAS:<p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>Formula:C24H17ClF2N6O4Purity:99.51% - 99.61%Color and Shape:SolidMolecular weight:526.88Tirapazamine
CAS:<p>Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.</p>Formula:C7H6N4O2Purity:96.65% - 99.87%Color and Shape:Orange-Red Crystalline PowderMolecular weight:178.15GAK inhibitor 49 hydrochloride
<p>Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.</p>Formula:C20H23ClN2O5Color and Shape:SolidMolecular weight:406.86PfDHODH-IN-1
CAS:<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formula:C14H11F3N2O2Purity:99.87%Color and Shape:SolidMolecular weight:296.24TP-353
CAS:<p>TP-353 (EOS-61973) is a CDK7 inhibitor.</p>Formula:C35H30FNO3Purity:99.12%Color and Shape:SolidMolecular weight:531.62ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formula:C31H43F6N9O12Purity:95.28% - ≥95%Color and Shape:SolidMolecular weight:847.72BI-1347
CAS:<p>BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.</p>Formula:C22H20N4OPurity:96.7% - 99.63%Color and Shape:SolidMolecular weight:356.42COH29
CAS:<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Formula:C22H16N2O5SPurity:97.04% - 98.92%Color and Shape:SolidMolecular weight:420.44Fialuridine
CAS:<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formula:C9H10FIN2O5Purity:99.71% - 99.88%Color and Shape:Less Crystals Colourless CrystalsMolecular weight:372.09Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Formula:C38H46N5NaO7S2Purity:98%Color and Shape:SolidMolecular weight:771.92SRI-29329
CAS:<p>SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).</p>Formula:C20H26ClN7Purity:99.18%Color and Shape:SolidMolecular weight:399.92NSC23005
CAS:<p>NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).</p>Formula:C13H17NO4SPurity:>99.99%Color and Shape:SolidMolecular weight:283.34Lifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Formula:C29H24Cl2N2O7SPurity:99.39% - 99.66%Color and Shape:SolidMolecular weight:615.48TH287 hydrochloride
CAS:<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formula:C11H11Cl3N4Purity:>99.99%Color and Shape:SolidMolecular weight:305.59ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formula:C10H12N6OPurity:99.69%Color and Shape:SolidMolecular weight:232.24ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Formula:C29H31N5O4Purity:99.11% - 99.59%Color and Shape:Pale Yellow SolidMolecular weight:513.59Trilaciclib
CAS:<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Formula:C24H30N8OPurity:99.624%Color and Shape:SolidMolecular weight:446.55Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Formula:CH12Na3O11PPurity:98%Color and Shape:SolidMolecular weight:300.03APTO-253 HCl
CAS:<p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>Formula:C22H15ClFN5Color and Shape:SolidMolecular weight:403.84HA-100 hydrochloride
CAS:<p>HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.</p>Formula:C13H16ClN3O2SColor and Shape:SolidMolecular weight:313.8LY3143921
CAS:<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Formula:C16H12FN5OColor and Shape:SolidMolecular weight:309.3Avotaciclib trihydrochloride
CAS:<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Formula:C13H14Cl3N7OPurity:99%Color and Shape:SolidMolecular weight:390.653'-Deoxyguanosine
CAS:<p>3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.</p>Formula:C10H13N5O4Purity:98.85% - 98.96%Color and Shape:SolidMolecular weight:267.24Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Formula:C12H17N5O4Purity:98.79%Color and Shape:White PowderMolecular weight:295.29Proguanil
CAS:<p>Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .</p>Formula:C11H16ClN5Purity:99.6%Color and Shape:SolidMolecular weight:253.73JSH-150
CAS:<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Formula:C24H33ClN6O2SPurity:99.96% - 99.96%Color and Shape:SolidMolecular weight:505.08Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Atuveciclib
CAS:<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Formula:C18H18FN5O2SPurity:98.8%Color and Shape:SolidMolecular weight:387.43Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53LY2880070
CAS:<p>LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.</p>Formula:C19H23N7O2Purity:99.77%Color and Shape:SolidMolecular weight:381.43BMS-1001
CAS:<p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>Formula:C35H34N2O7Purity:98.43%Color and Shape:SolidMolecular weight:594.7WNK-IN-11
CAS:<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Formula:C21H21Cl2N5OSPurity:98.32%Color and Shape:SolidMolecular weight:462.4BMS-5
CAS:<p>BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.</p>Formula:C17H14Cl2F2N4OSPurity:98.01% - 99.88%Color and Shape:SolidMolecular weight:431.292′-Deoxy-2′-fluoroguanosine
CAS:<p>2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).</p>Formula:C10H12FN5O4Purity:99.89%Color and Shape:SolidMolecular weight:285.23WR99210 hydrochloride(47326-86-3 free base)
CAS:<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Formula:C14H19Cl4N5O2Purity:97.77% - 99.8%Color and Shape:SolidMolecular weight:431.14LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.02Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Formula:C18H22BrN5O3Purity:98.86% - 99.87%Color and Shape:SolidMolecular weight:436.3TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33GNF2133 hydrochloride
CAS:<p>GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.</p>Formula:C24H31ClN6O2Color and Shape:SolidMolecular weight:471.0Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Formula:C38H47N5O7S2Purity:99.45% - 99.92%Color and Shape:SolidMolecular weight:749.94Aurora kinase inhibitor-3
CAS:<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4SBC-115337
CAS:<p>SBC-115337 is a PCSK9 inhibitor.</p>Formula:C29H19N3O4Purity:99.41%Color and Shape:SolidMolecular weight:473.48Y16 acetate(429653-73-6 free base)
<p>Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA</p>Formula:C51H74N14O13Purity:98%Color and Shape:SolidMolecular weight:1091.24Pritelivir
CAS:<p>Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).</p>Formula:C18H18N4O3S2Purity:97.96% - 99.42%Color and Shape:SolidMolecular weight:402.49Senexin A
CAS:<p>Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.</p>Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32LY2334737
CAS:<p>LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.</p>Formula:C17H25F2N3O5Purity:98.82%Color and Shape:SolidMolecular weight:389.39MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.465-BrdU
CAS:<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Formula:C9H11BrN2O5Purity:99.54% - 99.87%Color and Shape:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:307.1Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formula:C22H39ClN2O6SPurity:98.81% - >99.99%Color and Shape:White SolidMolecular weight:495.07ON-013100
CAS:<p>ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.</p>Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.4410074-G5
CAS:<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Formula:C18H12N4O3Purity:99.51% - 99.67%Color and Shape:SolidMolecular weight:332.31A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.32Fadraciclib
CAS:<p>Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).</p>Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52HMN-214
CAS:<p>HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.</p>Formula:C22H20N2O5SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:424.47TAK-960
CAS:<p>TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.</p>Formula:C27H34F3N7O3Purity:97.06%Color and Shape:SolidMolecular weight:561.6Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formula:C29H42F3N9O9Purity:98.99% - 99.54%Color and Shape:SolidMolecular weight:717.697BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17Hu7691
CAS:<p>Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.</p>Formula:C22H22ClF3N4OPurity:99.81%Color and Shape:SolidMolecular weight:450.88Seliciclib
CAS:<p>Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.</p>Formula:C19H26N6OPurity:97.15% - 99.89%Color and Shape:White To Off-White SolidMolecular weight:354.45InhA-IN-2
CAS:<p>N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.</p>Formula:C16H15ClN2O2S2Purity:98.4%Color and Shape:SolidMolecular weight:366.89360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Formula:C19H18BrIN4O2Purity:98.38% - 98.73%Color and Shape:SolidMolecular weight:541.18Mogroside I E1
CAS:<p>Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.</p>Formula:C36H62O9Purity:98.62% - 99.71%Color and Shape:SolidMolecular weight:638.87Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29Sarecycline free base
CAS:<p>Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.</p>Formula:C24H29N3O8Purity:98%Color and Shape:SolidMolecular weight:487.5AZD-5438
CAS:<p>AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).</p>Formula:C18H21N5O2SPurity:99.73% - 99.87%Color and Shape:SolidMolecular weight:371.46SPHINX
CAS:<p>SPHINX is a new generation inhibitor of SPRK1</p>Formula:C17H17F3N2O3Purity:99.29%Color and Shape:SolidMolecular weight:354.32
